RU2012134369A - Биомаркеры иммуномодулирующих эффектов у людей, подвергнутых лечению антиметаллами против cd200 - Google Patents
Биомаркеры иммуномодулирующих эффектов у людей, подвергнутых лечению антиметаллами против cd200 Download PDFInfo
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- RU2012134369A RU2012134369A RU2012134369/15A RU2012134369A RU2012134369A RU 2012134369 A RU2012134369 A RU 2012134369A RU 2012134369/15 A RU2012134369/15 A RU 2012134369/15A RU 2012134369 A RU2012134369 A RU 2012134369A RU 2012134369 A RU2012134369 A RU 2012134369A
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- antibody
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- G01N33/5759—
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- G—PHYSICS
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
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- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
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- Public Health (AREA)
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- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29406610P | 2010-01-11 | 2010-01-11 | |
| US61/294,066 | 2010-01-11 | ||
| US33799710P | 2010-02-11 | 2010-02-11 | |
| US61/337,997 | 2010-02-11 | ||
| US40144210P | 2010-08-12 | 2010-08-12 | |
| US61/401,442 | 2010-08-12 | ||
| US41697410P | 2010-11-24 | 2010-11-24 | |
| US61/416,974 | 2010-11-24 | ||
| PCT/US2011/020750 WO2011085343A1 (en) | 2010-01-11 | 2011-01-11 | Biomarkers of immunomodulatory effects in humans treated with anti-cd200 antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2012134369A true RU2012134369A (ru) | 2014-02-20 |
Family
ID=44305832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012134369/15A RU2012134369A (ru) | 2010-01-11 | 2011-01-11 | Биомаркеры иммуномодулирующих эффектов у людей, подвергнутых лечению антиметаллами против cd200 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9180186B2 (enExample) |
| EP (1) | EP2523976B1 (enExample) |
| JP (2) | JP6012473B2 (enExample) |
| KR (1) | KR20130005264A (enExample) |
| CN (1) | CN102906115A (enExample) |
| AU (1) | AU2011203879A1 (enExample) |
| CA (1) | CA2786692A1 (enExample) |
| IN (1) | IN2012DN06309A (enExample) |
| MX (1) | MX2012008108A (enExample) |
| NZ (1) | NZ601111A (enExample) |
| RU (1) | RU2012134369A (enExample) |
| SG (1) | SG182408A1 (enExample) |
| WO (1) | WO2011085343A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11090363B2 (en) | 2009-07-10 | 2021-08-17 | University of Pittsburgh—of the Commonwealth System of Higher Education | Vasoactive intestinal peptide release from microparticles |
| US8846098B2 (en) | 2009-07-10 | 2014-09-30 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Artificial cell constructs for cellular manipulation |
| CA2789623A1 (en) | 2010-02-11 | 2011-08-18 | Alexion Pharmaceutical, Inc. | Therapeutic methods using anti-cd200 antibodies |
| JP6150734B2 (ja) | 2011-02-03 | 2017-06-21 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 同種移植片の生存を長期化するための抗cd200抗体の使用 |
| CN102698266A (zh) * | 2012-05-15 | 2012-10-03 | 中国医学科学院北京协和医院 | Cd200在制备系统性红斑狼疮治疗药物中的应用 |
| AU2013285355A1 (en) | 2012-07-06 | 2015-01-29 | Genmab B.V. | Dimeric protein with triple mutations |
| EP2956772B1 (en) * | 2013-02-14 | 2018-05-30 | Faron Pharmaceuticals OY | A method for determining acute respiratory distress syndrome (ards) related biomarkers, a method to monitor the development and treatment of ards in a patient |
| JP7022067B2 (ja) * | 2016-01-14 | 2022-02-17 | メモリアル スローン ケタリング キャンサー センター | Foxp3由来のペプチドに特異的なt細胞受容体様抗体 |
| GB201608197D0 (en) * | 2016-05-10 | 2016-06-22 | Ducentis Biotherapeutics Ltd | Novel proteins |
| WO2018075408A1 (en) | 2016-10-17 | 2018-04-26 | Alexion Pharmaceuticals, Inc. | Methods of treating acute myeloid leukemia (aml) with combinations of anti-cd200 antibodies, cytarabine, and daunorubicin |
| WO2018102594A1 (en) | 2016-12-01 | 2018-06-07 | Alexion Pharmaceuticals, Inc. | Methods of treating solid tumors with anti-cd200 antibodies |
| CN118184781A (zh) * | 2017-05-08 | 2024-06-14 | 阿迪马布有限责任公司 | 抗cd3结合结构域和包含它们的抗体以及它们的产生及使用方法 |
| WO2019067499A1 (en) | 2017-09-27 | 2019-04-04 | Alexion Pharmaceuticals, Inc. | BIOMARKER SIGNATURE FOR PREDICTING A TUMOR RESPONSE TO ANTI-CD200 THERAPY |
| US11802154B2 (en) | 2017-12-20 | 2023-10-31 | Alexion Pharmaceuticals, Inc. | Humanized anti-CD200 antibodies and uses thereof |
| US12139533B2 (en) | 2017-12-20 | 2024-11-12 | Alexion Pharmaceuticals, Inc. | Liquid formulations of anti-CD200 antibodies |
| TWI749367B (zh) * | 2018-09-14 | 2021-12-11 | 美商美國禮來大藥廠 | Cd200r促效劑抗體及其用途 |
| EP4676955A2 (en) * | 2023-03-10 | 2026-01-14 | Ultragenyx Pharmaceutical Inc. | Human fgf23-binding antibodies with improved affinity and efficacy |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US599784A (en) | 1898-03-01 | Spout attachment for bottles | ||
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4634666A (en) | 1984-01-06 | 1987-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | Human-murine hybridoma fusion partner |
| WO1985003508A1 (en) | 1984-02-08 | 1985-08-15 | Cetus Corporation | Toxin conjugates |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| ATE114723T1 (de) | 1987-03-02 | 1994-12-15 | Enzon Lab Inc | Organismus als träger für ''single chain antibody domain (scad)''. |
| DE3883899T3 (de) | 1987-03-18 | 1999-04-22 | Sb2, Inc., Danville, Calif. | Geänderte antikörper. |
| JPH0246297A (ja) | 1988-08-08 | 1990-02-15 | Takeda Chem Ind Ltd | モノクローナル抗体、抗体産生ハイブリドーマおよび抗体の製造法 |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| US6075181A (en) | 1990-01-12 | 2000-06-13 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US20040010810A1 (en) | 1990-01-12 | 2004-01-15 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US6713610B1 (en) | 1990-01-12 | 2004-03-30 | Raju Kucherlapati | Human antibodies derived from immunized xenomice |
| US6673986B1 (en) | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6657103B1 (en) | 1990-01-12 | 2003-12-02 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
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-
2011
- 2011-01-11 NZ NZ601111A patent/NZ601111A/en not_active IP Right Cessation
- 2011-01-11 KR KR1020127020337A patent/KR20130005264A/ko not_active Withdrawn
- 2011-01-11 CA CA2786692A patent/CA2786692A1/en not_active Abandoned
- 2011-01-11 IN IN6309DEN2012 patent/IN2012DN06309A/en unknown
- 2011-01-11 EP EP11732296.6A patent/EP2523976B1/en active Active
- 2011-01-11 JP JP2012548220A patent/JP6012473B2/ja not_active Expired - Fee Related
- 2011-01-11 SG SG2012050142A patent/SG182408A1/en unknown
- 2011-01-11 RU RU2012134369/15A patent/RU2012134369A/ru not_active Application Discontinuation
- 2011-01-11 US US13/521,671 patent/US9180186B2/en active Active
- 2011-01-11 WO PCT/US2011/020750 patent/WO2011085343A1/en not_active Ceased
- 2011-01-11 AU AU2011203879A patent/AU2011203879A1/en not_active Abandoned
- 2011-01-11 CN CN2011800131799A patent/CN102906115A/zh active Pending
- 2011-01-11 MX MX2012008108A patent/MX2012008108A/es not_active Application Discontinuation
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2015
- 2015-05-26 JP JP2015106061A patent/JP2015155465A/ja not_active Withdrawn
- 2015-08-17 US US14/827,693 patent/US20160033514A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2523976B1 (en) | 2018-04-25 |
| EP2523976A1 (en) | 2012-11-21 |
| US20130202602A1 (en) | 2013-08-08 |
| US9180186B2 (en) | 2015-11-10 |
| MX2012008108A (es) | 2012-10-03 |
| WO2011085343A1 (en) | 2011-07-14 |
| SG182408A1 (en) | 2012-08-30 |
| EP2523976A4 (en) | 2013-10-30 |
| US20160033514A1 (en) | 2016-02-04 |
| KR20130005264A (ko) | 2013-01-15 |
| JP2015155465A (ja) | 2015-08-27 |
| JP2013516494A (ja) | 2013-05-13 |
| JP6012473B2 (ja) | 2016-10-25 |
| NZ601111A (en) | 2014-07-25 |
| AU2011203879A1 (en) | 2012-08-02 |
| CA2786692A1 (en) | 2011-07-14 |
| IN2012DN06309A (enExample) | 2015-09-25 |
| CN102906115A (zh) | 2013-01-30 |
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