JP5992325B2 - 乳癌のための、ネラチニブを活用する治療計画 - Google Patents
乳癌のための、ネラチニブを活用する治療計画 Download PDFInfo
- Publication number
- JP5992325B2 JP5992325B2 JP2012504700A JP2012504700A JP5992325B2 JP 5992325 B2 JP5992325 B2 JP 5992325B2 JP 2012504700 A JP2012504700 A JP 2012504700A JP 2012504700 A JP2012504700 A JP 2012504700A JP 5992325 B2 JP5992325 B2 JP 5992325B2
- Authority
- JP
- Japan
- Prior art keywords
- composition
- therapy
- neratinib
- trastuzumab
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16679609P | 2009-04-06 | 2009-04-06 | |
| US61/166,796 | 2009-04-06 | ||
| PCT/US2010/028448 WO2010117633A1 (en) | 2009-04-06 | 2010-03-24 | Treatment regimen utilizing neratinib for breast cancer |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014247707A Division JP2015044871A (ja) | 2009-04-06 | 2014-12-08 | 乳癌のための、ネラチニブを活用する治療計画 |
| JP2016103000A Division JP2016147912A (ja) | 2009-04-06 | 2016-05-24 | 乳癌のための、ネラチニブを活用する治療計画 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012522837A JP2012522837A (ja) | 2012-09-27 |
| JP2012522837A5 JP2012522837A5 (OSRAM) | 2013-04-11 |
| JP5992325B2 true JP5992325B2 (ja) | 2016-09-14 |
Family
ID=42313339
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012504700A Active JP5992325B2 (ja) | 2009-04-06 | 2010-03-24 | 乳癌のための、ネラチニブを活用する治療計画 |
| JP2014247707A Pending JP2015044871A (ja) | 2009-04-06 | 2014-12-08 | 乳癌のための、ネラチニブを活用する治療計画 |
| JP2016103000A Withdrawn JP2016147912A (ja) | 2009-04-06 | 2016-05-24 | 乳癌のための、ネラチニブを活用する治療計画 |
| JP2017231667A Withdrawn JP2018030891A (ja) | 2009-04-06 | 2017-12-01 | 乳癌のための、ネラチニブを活用する治療計画 |
| JP2019114554A Withdrawn JP2019151671A (ja) | 2009-04-06 | 2019-06-20 | 乳癌のための、ネラチニブを活用する治療計画 |
| JP2021065698A Withdrawn JP2021100985A (ja) | 2009-04-06 | 2021-04-08 | 乳癌のための、ネラチニブを活用する治療計画 |
| JP2023060682A Withdrawn JP2023076588A (ja) | 2009-04-06 | 2023-04-04 | 乳癌のための、ネラチニブを活用する治療計画 |
Family Applications After (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014247707A Pending JP2015044871A (ja) | 2009-04-06 | 2014-12-08 | 乳癌のための、ネラチニブを活用する治療計画 |
| JP2016103000A Withdrawn JP2016147912A (ja) | 2009-04-06 | 2016-05-24 | 乳癌のための、ネラチニブを活用する治療計画 |
| JP2017231667A Withdrawn JP2018030891A (ja) | 2009-04-06 | 2017-12-01 | 乳癌のための、ネラチニブを活用する治療計画 |
| JP2019114554A Withdrawn JP2019151671A (ja) | 2009-04-06 | 2019-06-20 | 乳癌のための、ネラチニブを活用する治療計画 |
| JP2021065698A Withdrawn JP2021100985A (ja) | 2009-04-06 | 2021-04-08 | 乳癌のための、ネラチニブを活用する治療計画 |
| JP2023060682A Withdrawn JP2023076588A (ja) | 2009-04-06 | 2023-04-04 | 乳癌のための、ネラチニブを活用する治療計画 |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US9211291B2 (OSRAM) |
| EP (3) | EP4218760A3 (OSRAM) |
| JP (7) | JP5992325B2 (OSRAM) |
| KR (6) | KR20140036332A (OSRAM) |
| CN (3) | CN102369010A (OSRAM) |
| AR (1) | AR076197A1 (OSRAM) |
| AU (1) | AU2010234968B2 (OSRAM) |
| BR (1) | BRPI1012699A2 (OSRAM) |
| CA (1) | CA2755789C (OSRAM) |
| CY (2) | CY1125948T1 (OSRAM) |
| DK (1) | DK3000467T3 (OSRAM) |
| ES (2) | ES2561495T3 (OSRAM) |
| FI (2) | FI3000467T3 (OSRAM) |
| FR (1) | FR23C1027I2 (OSRAM) |
| HR (1) | HRP20230315T1 (OSRAM) |
| HU (2) | HUE061640T2 (OSRAM) |
| IL (4) | IL305394B2 (OSRAM) |
| LT (2) | LT3000467T (OSRAM) |
| LU (1) | LUC00310I2 (OSRAM) |
| MX (1) | MX356593B (OSRAM) |
| NL (1) | NL301237I2 (OSRAM) |
| NO (1) | NO2023028I1 (OSRAM) |
| NZ (1) | NZ595143A (OSRAM) |
| PL (1) | PL3000467T3 (OSRAM) |
| PT (1) | PT3000467T (OSRAM) |
| RU (2) | RU2011139363A (OSRAM) |
| SG (1) | SG174382A1 (OSRAM) |
| SI (1) | SI3000467T1 (OSRAM) |
| SM (1) | SMT202300094T1 (OSRAM) |
| TW (2) | TWI557108B (OSRAM) |
| WO (1) | WO2010117633A1 (OSRAM) |
| ZA (1) | ZA201108118B (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113952459B (zh) | 2005-02-03 | 2025-02-11 | 综合医院公司 | 治疗吉非替尼耐药性癌症的方法 |
| CN103110948A (zh) | 2005-11-04 | 2013-05-22 | 惠氏公司 | mTOR抑制剂、赫赛汀和/或HKI-272的抗肿瘤组合 |
| US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
| CN102641270A (zh) | 2008-06-17 | 2012-08-22 | 惠氏有限责任公司 | 含有hki-272和长春瑞滨的抗肿瘤组合 |
| HUE032958T2 (hu) | 2008-08-04 | 2017-11-28 | Wyeth Llc | 4-Anilino-3-ciano-kinolinok és capecitabin antineoplasztikus kombinációi |
| LT3000467T (lt) | 2009-04-06 | 2023-04-11 | Wyeth Llc | Krūties vėžio gydymo schema naudojant neratinibą |
| EP2498751B1 (en) | 2009-11-09 | 2019-04-03 | Wyeth LLC | Coated drug spheroids and uses thereof for eliminating or reducing conditions such as emesis and diarrhea |
| KR20200022187A (ko) | 2018-08-22 | 2020-03-03 | 울산대학교 산학협력단 | Nono의 발현 또는 활성 억제제를 유효성분으로 포함하는 방사선 민감성 증진용 조성물 |
| CR20220241A (es) | 2019-11-04 | 2022-08-03 | Revolution Medicines Inc | Inhibidores de ras |
| US11690915B2 (en) | 2020-09-15 | 2023-07-04 | Revolution Medicines, Inc. | Ras inhibitors |
| EP4334325A1 (en) | 2021-05-05 | 2024-03-13 | Revolution Medicines, Inc. | Ras inhibitors for the treatment of cancer |
| AR127308A1 (es) | 2021-10-08 | 2024-01-10 | Revolution Medicines Inc | Inhibidores ras |
| CN120957726A (zh) * | 2023-03-21 | 2025-11-14 | 启德医药科技(苏州)有限公司 | 抗体-药物偶联物与癌症疗法的组合及其用途 |
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