JP5980942B2 - 冠循環のマルチスケールな解剖学的かつ機能的なモデリングの方法およびシステム - Google Patents
冠循環のマルチスケールな解剖学的かつ機能的なモデリングの方法およびシステム Download PDFInfo
- Publication number
- JP5980942B2 JP5980942B2 JP2014541362A JP2014541362A JP5980942B2 JP 5980942 B2 JP5980942 B2 JP 5980942B2 JP 2014541362 A JP2014541362 A JP 2014541362A JP 2014541362 A JP2014541362 A JP 2014541362A JP 5980942 B2 JP5980942 B2 JP 5980942B2
- Authority
- JP
- Japan
- Prior art keywords
- model
- coronary
- region
- generating
- blood flow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000004087 circulation Effects 0.000 title claims description 59
- 238000000034 method Methods 0.000 title claims description 36
- 210000004351 coronary vessel Anatomy 0.000 claims description 86
- 230000017531 blood circulation Effects 0.000 claims description 85
- 208000031481 Pathologic Constriction Diseases 0.000 claims description 83
- 230000036262 stenosis Effects 0.000 claims description 83
- 208000037804 stenosis Diseases 0.000 claims description 83
- 210000002216 heart Anatomy 0.000 claims description 60
- 238000004364 calculation method Methods 0.000 claims description 53
- 230000002966 stenotic effect Effects 0.000 claims description 49
- 238000005094 computer simulation Methods 0.000 claims description 23
- 230000000004 hemodynamic effect Effects 0.000 claims description 21
- 230000000694 effects Effects 0.000 claims description 19
- 230000001225 therapeutic effect Effects 0.000 claims description 19
- 210000000709 aorta Anatomy 0.000 claims description 14
- 230000033001 locomotion Effects 0.000 claims description 11
- 238000004088 simulation Methods 0.000 claims description 11
- 239000012530 fluid Substances 0.000 claims description 10
- 210000005240 left ventricle Anatomy 0.000 claims description 9
- 230000008878 coupling Effects 0.000 claims description 8
- 238000010168 coupling process Methods 0.000 claims description 8
- 238000005859 coupling reaction Methods 0.000 claims description 8
- 230000002792 vascular Effects 0.000 claims description 8
- 238000004590 computer program Methods 0.000 claims description 7
- 210000005003 heart tissue Anatomy 0.000 claims description 7
- 210000004088 microvessel Anatomy 0.000 claims description 7
- 230000000747 cardiac effect Effects 0.000 claims description 6
- 230000010339 dilation Effects 0.000 claims description 5
- 238000002513 implantation Methods 0.000 claims description 5
- 238000001356 surgical procedure Methods 0.000 claims description 5
- 230000001965 increasing effect Effects 0.000 claims description 3
- 230000010247 heart contraction Effects 0.000 claims description 2
- 210000004204 blood vessel Anatomy 0.000 description 29
- 230000036772 blood pressure Effects 0.000 description 23
- 208000029078 coronary artery disease Diseases 0.000 description 18
- 230000002107 myocardial effect Effects 0.000 description 13
- 238000002591 computed tomography Methods 0.000 description 10
- 230000008602 contraction Effects 0.000 description 9
- 210000001519 tissue Anatomy 0.000 description 9
- 238000013459 approach Methods 0.000 description 8
- 230000000877 morphologic effect Effects 0.000 description 8
- 238000002604 ultrasonography Methods 0.000 description 8
- 230000007246 mechanism Effects 0.000 description 7
- 210000004165 myocardium Anatomy 0.000 description 7
- 238000011156 evaluation Methods 0.000 description 6
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 230000001413 cellular effect Effects 0.000 description 5
- 230000003993 interaction Effects 0.000 description 5
- 230000002829 reductive effect Effects 0.000 description 5
- 201000000057 Coronary Stenosis Diseases 0.000 description 4
- 206010020565 Hyperaemia Diseases 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 210000001174 endocardium Anatomy 0.000 description 4
- 210000002889 endothelial cell Anatomy 0.000 description 4
- 230000012010 growth Effects 0.000 description 4
- 210000004115 mitral valve Anatomy 0.000 description 4
- 208000010125 myocardial infarction Diseases 0.000 description 4
- 230000000284 resting effect Effects 0.000 description 4
- 230000002861 ventricular Effects 0.000 description 4
- 206010011089 Coronary artery stenosis Diseases 0.000 description 3
- 210000001367 artery Anatomy 0.000 description 3
- 210000000748 cardiovascular system Anatomy 0.000 description 3
- 230000006835 compression Effects 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 230000034994 death Effects 0.000 description 3
- 231100000517 death Toxicity 0.000 description 3
- 230000001419 dependent effect Effects 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 238000005206 flow analysis Methods 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 230000000544 hyperemic effect Effects 0.000 description 3
- 238000003384 imaging method Methods 0.000 description 3
- 238000007726 management method Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 230000036961 partial effect Effects 0.000 description 3
- 238000011002 quantification Methods 0.000 description 3
- 210000005241 right ventricle Anatomy 0.000 description 3
- 206010003210 Arteriosclerosis Diseases 0.000 description 2
- 230000033115 angiogenesis Effects 0.000 description 2
- 238000002583 angiography Methods 0.000 description 2
- 210000001765 aortic valve Anatomy 0.000 description 2
- 210000002565 arteriole Anatomy 0.000 description 2
- 208000011775 arteriosclerosis disease Diseases 0.000 description 2
- 230000010455 autoregulation Effects 0.000 description 2
- 230000006399 behavior Effects 0.000 description 2
- 238000004422 calculation algorithm Methods 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 208000037998 chronic venous disease Diseases 0.000 description 2
- 238000002586 coronary angiography Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000002059 diagnostic imaging Methods 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 208000028867 ischemia Diseases 0.000 description 2
- 210000005246 left atrium Anatomy 0.000 description 2
- 238000002595 magnetic resonance imaging Methods 0.000 description 2
- 230000003387 muscular Effects 0.000 description 2
- 210000003102 pulmonary valve Anatomy 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 238000007634 remodeling Methods 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 210000005245 right atrium Anatomy 0.000 description 2
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 2
- 230000009466 transformation Effects 0.000 description 2
- 210000000591 tricuspid valve Anatomy 0.000 description 2
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 208000001953 Hypotension Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003872 anastomosis Effects 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 238000002399 angioplasty Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000003915 cell function Effects 0.000 description 1
- 230000007248 cellular mechanism Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000005229 chemical vapour deposition Methods 0.000 description 1
- 230000001447 compensatory effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000002380 cytological effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000002592 echocardiography Methods 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000003511 endothelial effect Effects 0.000 description 1
- 210000003038 endothelium Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 210000003709 heart valve Anatomy 0.000 description 1
- 230000036543 hypotension Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000008338 local blood flow Effects 0.000 description 1
- 238000013178 mathematical model Methods 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 230000010016 myocardial function Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000007505 plaque formation Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001902 propagating effect Effects 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 210000003492 pulmonary vein Anatomy 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000011218 segmentation Effects 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 238000002603 single-photon emission computed tomography Methods 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
- 230000006442 vascular tone Effects 0.000 description 1
- 210000001631 vena cava inferior Anatomy 0.000 description 1
- 210000002620 vena cava superior Anatomy 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C10/00—Computational theoretical chemistry, i.e. ICT specially adapted for theoretical aspects of quantum chemistry, molecular mechanics, molecular dynamics or the like
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/30—Prediction of properties of chemical compounds, compositions or mixtures
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/40—Searching chemical structures or physicochemical data
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C99/00—Subject matter not provided for in other groups of this subclass
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
- G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
- G16Z99/00—Subject matter not provided for in other main groups of this subclass
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
- G16H30/20—ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Bioinformatics & Computational Biology (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biomedical Technology (AREA)
- Databases & Information Systems (AREA)
- Pathology (AREA)
- Data Mining & Analysis (AREA)
- Computing Systems (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Evolutionary Biology (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Physiology (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161557935P | 2011-11-10 | 2011-11-10 | |
| US61/557,935 | 2011-11-10 | ||
| US13/672,781 US10162932B2 (en) | 2011-11-10 | 2012-11-09 | Method and system for multi-scale anatomical and functional modeling of coronary circulation |
| US13/672,781 | 2012-11-09 | ||
| PCT/US2012/064604 WO2013071219A1 (en) | 2011-11-10 | 2012-11-12 | Method and system for multi-scale anatomical and functional modeling of coronary circulation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014534889A JP2014534889A (ja) | 2014-12-25 |
| JP2014534889A5 JP2014534889A5 (enExample) | 2015-03-12 |
| JP5980942B2 true JP5980942B2 (ja) | 2016-08-31 |
Family
ID=47279046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014541362A Active JP5980942B2 (ja) | 2011-11-10 | 2012-11-12 | 冠循環のマルチスケールな解剖学的かつ機能的なモデリングの方法およびシステム |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10162932B2 (enExample) |
| EP (1) | EP2776960B1 (enExample) |
| JP (1) | JP5980942B2 (enExample) |
| KR (1) | KR20140091741A (enExample) |
| CN (2) | CN110085321B (enExample) |
| BR (1) | BR112014011342A2 (enExample) |
| IN (1) | IN2014CN03423A (enExample) |
| WO (1) | WO2013071219A1 (enExample) |
Families Citing this family (135)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8200466B2 (en) | 2008-07-21 | 2012-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Method for tuning patient-specific cardiovascular simulations |
| US9405886B2 (en) | 2009-03-17 | 2016-08-02 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining cardiovascular information |
| US8315812B2 (en) | 2010-08-12 | 2012-11-20 | Heartflow, Inc. | Method and system for patient-specific modeling of blood flow |
| US9119540B2 (en) * | 2010-09-16 | 2015-09-01 | Siemens Aktiengesellschaft | Method and system for non-invasive assessment of coronary artery disease |
| FR2978345B1 (fr) | 2011-07-25 | 2013-08-30 | Charam Khosrovaninejad | Dispositif chirurgical d'ancrage controle dans l'intestin. |
| US8965084B2 (en) * | 2012-01-19 | 2015-02-24 | Siemens Aktiengesellschaft | Blood flow computation in vessels with implanted devices |
| US9183763B2 (en) * | 2012-01-31 | 2015-11-10 | Vascular Simulations, Llc | Cardiac simulation device |
| US10229615B2 (en) | 2012-01-31 | 2019-03-12 | Vascular Simulations Inc. | Cardiac simulation device |
| US10034614B2 (en) * | 2012-02-29 | 2018-07-31 | General Electric Company | Fractional flow reserve estimation |
| JP5946127B2 (ja) | 2012-05-11 | 2016-07-05 | 富士通株式会社 | シミュレーション方法、シミュレーション装置、およびシミュレーションプログラム |
| US8548778B1 (en) * | 2012-05-14 | 2013-10-01 | Heartflow, Inc. | Method and system for providing information from a patient-specific model of blood flow |
| US9247918B2 (en) | 2012-07-09 | 2016-02-02 | Siemens Aktiengesellschaft | Computation of hemodynamic quantities from angiographic data |
| GB2519909A (en) * | 2012-08-10 | 2015-05-06 | Vita Sentry Ltd | Estimations of equivalent inner diameter of arterioles |
| US10398386B2 (en) | 2012-09-12 | 2019-09-03 | Heartflow, Inc. | Systems and methods for estimating blood flow characteristics from vessel geometry and physiology |
| US10433740B2 (en) | 2012-09-12 | 2019-10-08 | Heartflow, Inc. | Systems and methods for estimating ischemia and blood flow characteristics from vessel geometry and physiology |
| US10210956B2 (en) | 2012-10-24 | 2019-02-19 | Cathworks Ltd. | Diagnostically useful results in real time |
| EP2943902B1 (en) | 2012-10-24 | 2020-03-11 | CathWorks Ltd. | Automated measurement system and method for coronary artery disease scoring |
| US9858387B2 (en) * | 2013-01-15 | 2018-01-02 | CathWorks, LTD. | Vascular flow assessment |
| US10595807B2 (en) | 2012-10-24 | 2020-03-24 | Cathworks Ltd | Calculating a fractional flow reserve |
| JP6358590B2 (ja) | 2013-08-09 | 2018-07-18 | 富士通株式会社 | 血管データ生成装置、血管データ生成方法、および血管データ生成プログラム |
| US9805463B2 (en) * | 2013-08-27 | 2017-10-31 | Heartflow, Inc. | Systems and methods for predicting location, onset, and/or change of coronary lesions |
| US9462954B2 (en) * | 2013-09-04 | 2016-10-11 | Siemens Aktiengesellschaft | Method and system for blood flow velocity reconstruction from medical images |
| WO2015032647A1 (en) | 2013-09-06 | 2015-03-12 | Koninklijke Philips N.V. | Processing apparatus for processing cardiac data |
| US10595806B2 (en) | 2013-10-22 | 2020-03-24 | Koninklijke Philips N.V. | Fractional flow reserve (FFR) index with adaptive boundary condition parameters |
| US9092743B2 (en) | 2013-10-23 | 2015-07-28 | Stenomics, Inc. | Machine learning system for assessing heart valves and surrounding cardiovascular tracts |
| EP3954298A3 (en) | 2013-10-24 | 2022-03-16 | Cathworks Ltd. | Vascular characteristic determination with correspondence modeling of a vascular tree |
| WO2015069202A1 (en) * | 2013-11-08 | 2015-05-14 | Piskin Senol | Operation scenario flow and mechanical modeling and analysis system of cardiovascular repair operations for newborn and foetus |
| CN105792738B (zh) | 2013-12-04 | 2020-03-13 | 皇家飞利浦有限公司 | 用于改善功能狭窄分析的局部ffr估计和可视化 |
| US20150164451A1 (en) * | 2013-12-18 | 2015-06-18 | Heartflow, Inc. | Systems and methods for predicting coronary plaque vulnerability from patient-specific anatomic image data |
| JP6835587B2 (ja) * | 2014-02-19 | 2021-02-24 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | 医用４ｄイメージングにおける動き適応型可視化 |
| JP6262027B2 (ja) | 2014-03-10 | 2018-01-17 | 東芝メディカルシステムズ株式会社 | 医用画像処理装置 |
| JP2015171486A (ja) * | 2014-03-12 | 2015-10-01 | 国立大学法人大阪大学 | 血流解析システムおよび血流解析プログラム |
| US9390232B2 (en) | 2014-03-24 | 2016-07-12 | Heartflow, Inc. | Systems and methods for modeling changes in patient-specific blood vessel geometry and boundary conditions |
| US9087147B1 (en) * | 2014-03-31 | 2015-07-21 | Heartflow, Inc. | Systems and methods for determining blood flow characteristics using flow ratio |
| US9773219B2 (en) | 2014-04-01 | 2017-09-26 | Heartflow, Inc. | Systems and methods for using geometry sensitivity information for guiding workflow |
| US10354349B2 (en) | 2014-04-01 | 2019-07-16 | Heartflow, Inc. | Systems and methods for using geometry sensitivity information for guiding workflow |
| US9595089B2 (en) * | 2014-05-09 | 2017-03-14 | Siemens Healthcare Gmbh | Method and system for non-invasive computation of hemodynamic indices for coronary artery stenosis |
| JP2015217113A (ja) * | 2014-05-16 | 2015-12-07 | 株式会社東芝 | 血管解析装置、医用画像診断装置、血管解析方法及び血管解析プログラム |
| US10130266B2 (en) | 2014-06-30 | 2018-11-20 | Siemens Healthcare Gmbh | Method and system for prediction of post-stenting hemodynamic metrics for treatment planning of arterial stenosis |
| CN106659400B (zh) * | 2014-06-30 | 2021-01-05 | 皇家飞利浦有限公司 | 用于确定血流储备分数值的装置 |
| US9888968B2 (en) | 2014-07-22 | 2018-02-13 | Siemens Healthcare Gmbh | Method and system for automated therapy planning for arterial stenosis |
| US9195801B1 (en) | 2014-08-05 | 2015-11-24 | Heartflow, Inc. | Systems and methods for treatment planning based on plaque progression and regression curves |
| US9594876B2 (en) * | 2014-11-04 | 2017-03-14 | Heartflow, Inc. | Systems and methods for simulation of occluded arteries and optimization of occlusion-based treatments |
| US9349178B1 (en) | 2014-11-24 | 2016-05-24 | Siemens Aktiengesellschaft | Synthetic data-driven hemodynamic determination in medical imaging |
| WO2016115206A1 (en) | 2015-01-14 | 2016-07-21 | Heartflow, Inc. | Systems and methods for embolism prediction using embolus source and destination probabilities |
| DE102015202286A1 (de) | 2015-02-10 | 2016-08-11 | Siemens Healthcare Gmbh | Verfahren zur Erzeugung eines Fertigungsmodells für ein medizinisches Implantat |
| US10478130B2 (en) | 2015-02-13 | 2019-11-19 | Siemens Healthcare Gmbh | Plaque vulnerability assessment in medical imaging |
| EP3062248A1 (en) * | 2015-02-27 | 2016-08-31 | Pie Medical Imaging BV | Method and apparatus for quantitative flow analysis |
| WO2016164809A1 (en) | 2015-04-10 | 2016-10-13 | Heartflow, Inc. | System and method for vascular tree generation using patient-specific structural and functional data, and joint prior information |
| WO2016182508A1 (en) * | 2015-05-12 | 2016-11-17 | Singapore Health Services Pte Ltd | Medical image processing methods and systems |
| KR101977294B1 (ko) * | 2015-06-05 | 2019-05-10 | 서울대학교산학협력단 | 전산유체역학을 이용한 기관지 분석 방법 및 그 장치 |
| US10872698B2 (en) * | 2015-07-27 | 2020-12-22 | Siemens Healthcare Gmbh | Method and system for enhancing medical image-based blood flow computations using physiological measurements |
| WO2017021201A1 (en) | 2015-08-05 | 2017-02-09 | Koninklijke Philips N.V. | Assistance device and method for an interventional hemodynamic measurement |
| JP6818492B2 (ja) | 2015-10-05 | 2021-01-20 | キヤノンメディカルシステムズ株式会社 | 画像処理装置、画像処理方法、及びプログラム |
| EP3359041B1 (en) * | 2015-10-07 | 2021-03-03 | Koninklijke Philips N.V. | Mobile ffr simulation |
| CN108348206B (zh) | 2015-11-05 | 2022-07-29 | 皇家飞利浦有限公司 | 用于无创血流储备分数(ffr)的侧支流建模 |
| JP6918794B2 (ja) | 2015-11-10 | 2021-08-11 | ハートフロー， インコーポレイテッド | 解剖モデリングシステム及びその作動方法 |
| WO2017091492A1 (en) | 2015-11-23 | 2017-06-01 | Heartflow, Inc. | Systems and methods for assessing organ and/or tissue transplantation by simulating one or more transplant characteristics |
| US11191490B2 (en) | 2015-12-02 | 2021-12-07 | Siemens Healthcare Gmbh | Personalized assessment of patients with acute coronary syndrome |
| KR101954272B1 (ko) * | 2016-01-28 | 2019-03-05 | 연세대학교 산학협력단 | 유체-구조 상호작용을 고려한 협착 병변 영역의 혈류역학 시뮬레이션 방법 |
| WO2017147500A1 (en) | 2016-02-26 | 2017-08-31 | Heartflow, Inc. | Systems and methods for identifying and modeling unresolved vessels in image-based patient-specific hemodynamic models |
| DE102016203860A1 (de) | 2016-03-09 | 2017-09-14 | Siemens Healthcare Gmbh | Vorrichtung und Verfahren zum Ermitteln zumindest eines individuellen fluiddynamischen Kennwerts einer Stenose in einem mehrere serielle Stenosen aufweisenden Gefäßsegment |
| US10971271B2 (en) * | 2016-04-12 | 2021-04-06 | Siemens Healthcare Gmbh | Method and system for personalized blood flow modeling based on wearable sensor networks |
| EP4241694A3 (en) | 2016-05-16 | 2023-12-20 | Cathworks Ltd. | Selection of vascular paths from images |
| JP7036742B2 (ja) | 2016-05-16 | 2022-03-15 | キャスワークス リミテッド | 血管評価システム |
| CN106073894B (zh) * | 2016-05-31 | 2017-08-08 | 博动医学影像科技（上海）有限公司 | 基于植入虚拟支架的血管压力降数值及血流储备分数的评估方法和系统 |
| WO2018018033A1 (en) * | 2016-07-22 | 2018-01-25 | Cornell University | Rapid prototyping and in vitro modeling of patient-specific coronary artery bypass grafts |
| US11298104B2 (en) * | 2016-08-10 | 2022-04-12 | Canon Medical Systems Corporation | Medical processing apparatus, ultrasound diagnostic apparatus, and medical processing method |
| CN106308838B (zh) * | 2016-08-29 | 2019-06-07 | 于洋 | 一种ct图像处理装置 |
| WO2018050806A1 (en) * | 2016-09-16 | 2018-03-22 | Koninklijke Philips N.V. | Apparatus and method for determining a fractional flow reserve |
| US10945606B2 (en) | 2016-09-20 | 2021-03-16 | Heartflow, Inc. | System and methods for estimation of blood flow characteristics using reduced order model and machine learning |
| WO2018089413A1 (en) * | 2016-11-08 | 2018-05-17 | President And Fellows Of Harvard College | Methodology and apparatus for simulation of medical devices |
| CN106361429B (zh) * | 2016-11-10 | 2018-09-11 | 西安电子科技大学 | 借助3d打印实现先心病手术方案术前评估装置和方法 |
| CN110268478B (zh) * | 2016-12-15 | 2023-07-28 | 斯特凡Tto有限公司 | 提供用于心血管疾病的决策支持和诊断的受试者特异性计算模型的方法和过程 |
| CN108122616B (zh) * | 2016-12-28 | 2020-12-25 | 北京昆仑医云科技有限公司 | 个体特异性的心血管模型的生成方法及其应用 |
| EP4393386A3 (en) | 2017-01-23 | 2024-09-11 | Shanghai United Imaging Healthcare Co., Ltd. | Method and system for analyzing blood flow condition |
| US11918291B2 (en) * | 2017-03-31 | 2024-03-05 | Koninklijke Philips N.V. | Simulation of transcatheter aortic valve implantation (TAVI) induced effects on coronary flow and pressure |
| CN110494081A (zh) | 2017-04-06 | 2019-11-22 | 皇家飞利浦有限公司 | 基于根据ecg信号对心肌微血管阻力的估计的冠状动脉疾病度量 |
| CN107411819B (zh) * | 2017-04-12 | 2021-08-10 | 上海大学 | 球囊血管成形手术过程实时模拟方法 |
| CN110809801A (zh) * | 2017-05-04 | 2020-02-18 | 皇家飞利浦有限公司 | 用于血管中壁面剪切应力的同时可视化和量化的系统和方法 |
| US10909676B2 (en) * | 2017-07-12 | 2021-02-02 | Siemens Healthcare Gmbh | Method and system for clinical decision support with local and remote analytics |
| CN110998744B (zh) | 2017-08-01 | 2024-04-05 | 西门子医疗有限公司 | 针对弥漫性和串联性病变中冠状动脉疾病的非侵入性评估和治疗指导 |
| KR102744520B1 (ko) | 2017-10-06 | 2024-12-20 | 에모리 유니버시티 | 하나 이상의 동맥 세그먼트에 대한 혈역학 정보를 결정하기 위한 방법 및 시스템 |
| EP3494893A1 (en) | 2017-12-05 | 2019-06-12 | Koninklijke Philips N.V. | Ultrasound imaging system and method |
| FR3072557B1 (fr) | 2017-10-19 | 2019-11-08 | Safeheal | Dispositif chirurgical complexe pour la realisation et protection d'une anastomose. |
| US11605447B2 (en) | 2017-10-27 | 2023-03-14 | Siemens Healthcare Gmbh | Intelligent agents for patient management |
| EP3489893B1 (en) * | 2017-11-22 | 2020-06-24 | Siemens Healthcare GmbH | Method and system for assessing a haemodynamic parameter |
| JP6530043B2 (ja) * | 2017-12-12 | 2019-06-12 | キヤノンメディカルシステムズ株式会社 | 医用画像処理装置、医用画像処理方法および記録媒体 |
| WO2019173830A1 (en) * | 2018-03-09 | 2019-09-12 | Emory University | Methods and systems for determining coronary hemodynamic characteristic(s) that is predictive of myocardial infarction |
| US11389130B2 (en) | 2018-05-02 | 2022-07-19 | Siemens Healthcare Gmbh | System and methods for fast computation of computed tomography based fractional flow reserve |
| US12100516B2 (en) * | 2018-05-31 | 2024-09-24 | Corflow Therapeutics Ag | Microfluidic coronary circulatory model |
| JP7314183B2 (ja) * | 2018-06-15 | 2023-07-25 | パイ メディカル イメージング ビー ヴイ | 定量的血行動態フロー分析のための方法および装置 |
| KR102078622B1 (ko) * | 2018-06-28 | 2020-04-07 | 연세대학교 산학협력단 | 협착 병변의 수학적 모델링을 이용한 심혈관 정보 결정 방법 |
| KR102189311B1 (ko) * | 2018-08-21 | 2020-12-09 | 두산중공업 주식회사 | 학습된 모델을 이용한 해석 장치 및 이를 위한 방법 |
| KR102138227B1 (ko) * | 2018-08-21 | 2020-07-27 | 두산중공업 주식회사 | 유동 해석을 최적화하기 위한 장치 및 이를 위한 방법 |
| EP3613351A1 (en) * | 2018-08-22 | 2020-02-26 | Koninklijke Philips N.V. | Coronary circulation using intra-cardiac echo |
| GB201820044D0 (en) * | 2018-10-29 | 2019-01-23 | Univ Oxford Innovation Ltd | Radiomic signature of an epicardial region |
| JP7464997B2 (ja) * | 2018-09-21 | 2024-04-10 | メンティス アー・ベー | 心臓シミュレーション装置 |
| CN112384137B (zh) * | 2018-11-13 | 2023-11-14 | 苏州润迈德医疗科技有限公司 | 基于造影图像获取静息态下血管评定参数的方法及装置 |
| US10964017B2 (en) * | 2018-11-15 | 2021-03-30 | General Electric Company | Deep learning for arterial analysis and assessment |
| JP7233209B2 (ja) * | 2018-12-03 | 2023-03-06 | 朝日インテック株式会社 | 心臓シミュレータ |
| EP3671494A1 (en) * | 2018-12-21 | 2020-06-24 | Dassault Systèmes | Multi-instanced simulations for large environments |
| CN109700574B (zh) * | 2018-12-21 | 2021-01-05 | 北京工业大学 | 一种基于ct影像数据制备钙化主动脉瓣的方法 |
| CN109700475B (zh) * | 2018-12-27 | 2021-01-08 | 浙江大学 | 一种冠脉搭桥参数的确定方法、装置、设备和存储介质 |
| JP7241183B2 (ja) * | 2019-01-11 | 2023-03-16 | ヘモレンズ ダイアグノスティックス エスピー．ゼット オー．オー． | 冠動脈における血行動態パラメータの患者固有モデリング |
| CN109872336B (zh) * | 2019-03-13 | 2021-07-09 | 数坤(北京)网络科技股份有限公司 | 一种血管分割方法、设备及计算机存储介质 |
| JP7532402B2 (ja) | 2019-04-01 | 2024-08-13 | キャスワークス リミテッド | 血管造影画像選択のための方法および装置 |
| US10861157B2 (en) | 2019-04-04 | 2020-12-08 | Medtronic Vascular, Inc. | System and methods for determining modified fractional flow reserve values |
| US11357573B2 (en) | 2019-04-25 | 2022-06-14 | International Business Machines Corporation | Optimum treatment planning during coronary intervention by simultaneous simulation of a continuum of outcomes |
| JP6751178B2 (ja) * | 2019-05-14 | 2020-09-02 | キヤノンメディカルシステムズ株式会社 | 医用画像処理装置、医用画像処理方法および記録媒体 |
| CN110368087B (zh) * | 2019-06-06 | 2021-01-08 | 中国人民解放军北部战区总医院 | 一种信息处理方法和装置、及可读存储介质 |
| CN110310744B (zh) * | 2019-06-10 | 2021-12-24 | 暨南大学 | 窦房结虚拟生理组织的构建方法、存储介质和计算设备 |
| EP4555935A3 (en) | 2019-09-23 | 2025-07-30 | Cathworks Ltd. | Methods, apparatus, and system for synchronization between a three-dimensional vascular model and an imaging device |
| KR102130254B1 (ko) * | 2019-10-15 | 2020-07-03 | 주식회사 실리콘사피엔스 | 대상자 고유의 혈관에 대한 혈류 시뮬레이션 방법 및 장치 |
| US12096986B2 (en) | 2019-12-05 | 2024-09-24 | The Board Of Regents Of The University Of Nebraska | Computational simulation platform for planning of interventional procedures |
| US11026749B1 (en) * | 2019-12-05 | 2021-06-08 | Board Of Regents Of The University Of Nebraska | Computational simulation platform for planning of interventional procedures |
| CN111241759B (zh) * | 2020-01-13 | 2024-03-26 | 北京工业大学 | 一种基于零维血流动力学模型的ffr快速计算方法 |
| DE102020200750A1 (de) * | 2020-01-22 | 2021-07-22 | Siemens Healthcare Gmbh | Bereitstellen eines Blutflussparametersatzes einer Gefäßmalformation |
| CN111317455B (zh) * | 2020-03-03 | 2022-02-22 | 上海联影医疗科技股份有限公司 | 血流动力学参数确定方法、装置、设备及存储介质 |
| CN111616678B (zh) * | 2020-04-17 | 2023-04-14 | 清华大学 | 一种基于智能冠状动脉支架的再狭窄监测装置及方法 |
| US11538153B2 (en) * | 2020-08-31 | 2022-12-27 | Huidan Yu | Non-invasive functional assessment technique for determining hemodynamic severity of an arterial stenosis |
| CN112617791B (zh) * | 2020-12-22 | 2022-09-20 | 杭州晟视科技有限公司 | 一种模拟血管搏动的方法、装置及存储介质 |
| WO2022136688A1 (en) * | 2020-12-23 | 2022-06-30 | Flowreserve Labs S.L. | Non-invasive method for determining a vessel damage indicator |
| CN112950537A (zh) * | 2021-01-26 | 2021-06-11 | 上海友脉科技有限责任公司 | 一种冠脉血流储备分数获取系统、方法及介质 |
| US20220378506A1 (en) * | 2021-05-27 | 2022-12-01 | Board Of Regents Of The University Of Nebraska | Patient-specific computational simulation of coronary artery bypass grafting |
| CN113658701B (zh) * | 2021-08-26 | 2024-08-23 | 上海联影医疗科技股份有限公司 | 术后评估方法、计算机设备和存储介质 |
| CN113648059B (zh) * | 2021-08-26 | 2023-09-29 | 上海联影医疗科技股份有限公司 | 手术规划评估方法、计算机设备和存储介质 |
| US12315076B1 (en) | 2021-09-22 | 2025-05-27 | Cathworks Ltd. | Four-dimensional motion analysis of a patient's coronary arteries and myocardial wall |
| CN118985005A (zh) | 2022-02-10 | 2024-11-19 | 凯思沃克斯有限公司 | 用于基于机器学习的传感器分析和血管树分割的系统和方法 |
| CN115115735B (zh) * | 2022-06-29 | 2024-07-23 | 温州医科大学附属第二医院（温州医科大学附属育英儿童医院） | 一种基于多期相冠脉ct造影的内皮动应变的快速计算系统 |
| EP4410212A1 (en) * | 2023-02-02 | 2024-08-07 | Koninklijke Philips N.V. | Vascular diagnostic apparatus and method |
| US12239321B2 (en) | 2023-03-17 | 2025-03-04 | SafeHeal SAS | Systems and methods for introducing and monitoring a negative pressure device for protecting an intestinal anastomosis |
| US12446965B2 (en) | 2023-08-09 | 2025-10-21 | Cathworks Ltd. | Enhanced user interface and crosstalk analysis for vascular index measurement |
| WO2025214321A1 (zh) * | 2024-04-07 | 2025-10-16 | 深圳迈瑞生物医疗电子股份有限公司 | 一种目标部位的病变模型生成方法及装置 |
| CN119786054A (zh) * | 2024-12-26 | 2025-04-08 | 中国科学院深圳先进技术研究院 | 一种血流数值模拟方法、装置、计算机设备及存储介质 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10026666A1 (de) | 2000-05-29 | 2001-12-20 | Gunther Burgard | Verwendung von Hyaluronidase zur Prophylaxe und Behandlung von Herz-Kreislauf-Erkrankungen |
| US7912528B2 (en) * | 2003-06-25 | 2011-03-22 | Siemens Medical Solutions Usa, Inc. | Systems and methods for automated diagnosis and decision support for heart related diseases and conditions |
| CN101355904B (zh) | 2005-12-20 | 2012-01-11 | 皇家飞利浦电子股份有限公司 | 用于重建至少一部分目标的精密再现的重建单元 |
| US7860290B2 (en) | 2006-04-21 | 2010-12-28 | Siemens Medical Solutions Usa, Inc. | Three-dimensional (3D) modeling of coronary arteries |
| US7953266B2 (en) | 2007-02-06 | 2011-05-31 | Siemens Medical Solutions Usa, Inc. | Robust vessel tree modeling |
| US8098918B2 (en) | 2007-09-21 | 2012-01-17 | Siemens Corporation | Method and system for measuring left ventricle volume |
| US20110093243A1 (en) | 2007-11-14 | 2011-04-21 | Tawhai Merryn H | Method for multi-scale meshing of branching biological structures |
| WO2009099340A1 (en) * | 2008-02-04 | 2009-08-13 | Iain Alexander Anderson | Integrated-model musculoskeletal therapies |
| US9427173B2 (en) * | 2008-05-09 | 2016-08-30 | General Electric Company | Determining mechanical force on aneurysms from a fluid dynamic model driven by vessel blood flow information |
| JP5089514B2 (ja) | 2008-07-11 | 2012-12-05 | キヤノン株式会社 | 撮像装置、及び撮像システム |
| US8200466B2 (en) | 2008-07-21 | 2012-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Method for tuning patient-specific cardiovascular simulations |
| US8582854B2 (en) * | 2008-09-15 | 2013-11-12 | Siemens Aktiengesellschaft | Method and system for automatic coronary artery detection |
| US9405996B2 (en) * | 2008-09-18 | 2016-08-02 | Siemens Aktiengesellschaft | Method and system for generating a personalized anatomical heart model |
| US9405886B2 (en) | 2009-03-17 | 2016-08-02 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining cardiovascular information |
| US9715637B2 (en) | 2009-03-18 | 2017-07-25 | Siemens Healthcare Gmbh | Method and system for automatic aorta segmentation |
| US8224640B2 (en) | 2009-09-08 | 2012-07-17 | Siemens Aktiengesellschaft | Method and system for computational modeling of the aorta and heart |
| JP5721721B2 (ja) | 2009-09-23 | 2015-05-20 | ライトラボ・イメージング・インコーポレーテッド | 管腔形態および血管抵抗測定データ収集のシステム、装置および方法 |
| US8526699B2 (en) | 2010-03-12 | 2013-09-03 | Siemens Aktiengesellschaft | Method and system for automatic detection and classification of coronary stenoses in cardiac CT volumes |
| US20110270051A1 (en) * | 2010-05-03 | 2011-11-03 | Morteza Naghavi | Cardiovascular Disease Screening Method and Apparatus |
| US8682626B2 (en) | 2010-07-21 | 2014-03-25 | Siemens Aktiengesellschaft | Method and system for comprehensive patient-specific modeling of the heart |
| US8315812B2 (en) | 2010-08-12 | 2012-11-20 | Heartflow, Inc. | Method and system for patient-specific modeling of blood flow |
| US8157742B2 (en) | 2010-08-12 | 2012-04-17 | Heartflow, Inc. | Method and system for patient-specific modeling of blood flow |
| DE102010039312B4 (de) | 2010-08-13 | 2020-02-13 | Siemens Healthcare Gmbh | Verfahren zur Simulation eines Blutflusses |
| US9119540B2 (en) | 2010-09-16 | 2015-09-01 | Siemens Aktiengesellschaft | Method and system for non-invasive assessment of coronary artery disease |
| DE102010043849B3 (de) | 2010-11-12 | 2012-02-16 | Siemens Aktiengesellschaft | Vorrichtung und Computertomograph zur Bestimmung und Darstellung der Durchblutung des Herzmuskels |
| US9141763B2 (en) | 2011-02-07 | 2015-09-22 | Siemens Aktiengesellschaft | Method and system for patient-specific computational modeling and simulation for coupled hemodynamic analysis of cerebral vessels |
-
2012
- 2012-11-09 US US13/672,781 patent/US10162932B2/en active Active
- 2012-11-12 CN CN201910202025.2A patent/CN110085321B/zh active Active
- 2012-11-12 JP JP2014541362A patent/JP5980942B2/ja active Active
- 2012-11-12 IN IN3423CHN2014 patent/IN2014CN03423A/en unknown
- 2012-11-12 KR KR1020147015738A patent/KR20140091741A/ko not_active Ceased
- 2012-11-12 CN CN201280066658.1A patent/CN104081401A/zh active Pending
- 2012-11-12 BR BR112014011342A patent/BR112014011342A2/pt not_active Application Discontinuation
- 2012-11-12 EP EP12795185.3A patent/EP2776960B1/en active Active
- 2012-11-12 WO PCT/US2012/064604 patent/WO2013071219A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IN2014CN03423A (enExample) | 2015-07-03 |
| EP2776960A1 (en) | 2014-09-17 |
| US10162932B2 (en) | 2018-12-25 |
| JP2014534889A (ja) | 2014-12-25 |
| KR20140091741A (ko) | 2014-07-22 |
| US20130132054A1 (en) | 2013-05-23 |
| BR112014011342A2 (pt) | 2017-05-02 |
| CN110085321B (zh) | 2023-10-27 |
| WO2013071219A1 (en) | 2013-05-16 |
| EP2776960B1 (en) | 2021-09-01 |
| CN110085321A (zh) | 2019-08-02 |
| CN104081401A (zh) | 2014-10-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5980942B2 (ja) | 冠循環のマルチスケールな解剖学的かつ機能的なモデリングの方法およびシステム | |
| US12059288B2 (en) | Systems and methods for assessing the severity of plaque and/or stenotic lesions using contrast distribution predictions and measurements | |
| CN105976348B (zh) | 医学成像中的个性化全身循环 | |
| US10299862B2 (en) | Three-dimensional quantitative heart hemodynamics in medical imaging | |
| US8527251B2 (en) | Method and system for multi-component heart and aorta modeling for decision support in cardiac disease | |
| US11393593B2 (en) | Biological simulation apparatus and biological simulation apparatus control method | |
| CN105078440B (zh) | 无创计算冠状动脉狭窄的血液动力学指标的方法和系统 | |
| CN105249954B (zh) | 预测支架术后血液动力学指标的方法和系统 | |
| US10872698B2 (en) | Method and system for enhancing medical image-based blood flow computations using physiological measurements | |
| US8224640B2 (en) | Method and system for computational modeling of the aorta and heart | |
| US7828735B2 (en) | Methods for providing diagnostic information using endocardial surface data for a patient's heart | |
| KR102401542B1 (ko) | 관동맥 병변들의 위치, 발병, 및/또는 변화를 예측하기 위한 시스템들 및 방법들 | |
| CN108294735B (zh) | 用于冠状动脉狭窄的非侵入性功能评估的方法和系统 | |
| US8682626B2 (en) | Method and system for comprehensive patient-specific modeling of the heart | |
| JP5868052B2 (ja) | 包括的な患者固有の心臓のモデリング方法およびシステム | |
| CN114530252A (zh) | 冠状动脉血流动力学模拟仿真方法及装置 | |
| Khodaei et al. | Long-term prognostic impact of paravalvular leakage on coronary artery disease requires patient-specific quantification of hemodynamics | |
| Soni et al. | A comprehensive review on CFD simulations of left ventricle hemodynamics: numerical methods, experimental validation techniques, and emerging trends | |
| Ralovich et al. | Hemodynamic assessment of pre-and post-operative aortic coarctation from MRI | |
| Ding et al. | Simulating impaired left ventricular–arterial coupling in aging and disease: a systematic review | |
| Sadeghi | Impacts of Coarctation Coexisting with Other Cardiovascular Diseases on Hemodynamics Using Patient Specific Lumped Parameter and Lattice Boltzmann Modeling | |
| CN102346811B (zh) | 用于对心脏进行特定于患者的综合性建模的方法和系统 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150123 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20150123 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20151202 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20151207 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20160627 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20160727 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 5980942 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |