CN110085321B - 对冠脉循环进行多尺度的解剖学和功能建模的方法和系统 - Google Patents
对冠脉循环进行多尺度的解剖学和功能建模的方法和系统 Download PDFInfo
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- CN110085321B CN110085321B CN201910202025.2A CN201910202025A CN110085321B CN 110085321 B CN110085321 B CN 110085321B CN 201910202025 A CN201910202025 A CN 201910202025A CN 110085321 B CN110085321 B CN 110085321B
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910202025.2A CN110085321B (zh) | 2011-11-10 | 2012-11-12 | 对冠脉循环进行多尺度的解剖学和功能建模的方法和系统 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161557935P | 2011-11-10 | 2011-11-10 | |
| US61/557,935 | 2011-11-10 | ||
| US13/672,781 | 2012-11-09 | ||
| US13/672,781 US10162932B2 (en) | 2011-11-10 | 2012-11-09 | Method and system for multi-scale anatomical and functional modeling of coronary circulation |
| CN201910202025.2A CN110085321B (zh) | 2011-11-10 | 2012-11-12 | 对冠脉循环进行多尺度的解剖学和功能建模的方法和系统 |
| PCT/US2012/064604 WO2013071219A1 (en) | 2011-11-10 | 2012-11-12 | Method and system for multi-scale anatomical and functional modeling of coronary circulation |
| CN201280066658.1A CN104081401A (zh) | 2011-11-10 | 2012-11-12 | 用于对冠脉循环进行多尺度的解剖学和功能建模的方法和系统 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280066658.1A Division CN104081401A (zh) | 2011-11-10 | 2012-11-12 | 用于对冠脉循环进行多尺度的解剖学和功能建模的方法和系统 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110085321A CN110085321A (zh) | 2019-08-02 |
| CN110085321B true CN110085321B (zh) | 2023-10-27 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910202025.2A Active CN110085321B (zh) | 2011-11-10 | 2012-11-12 | 对冠脉循环进行多尺度的解剖学和功能建模的方法和系统 |
| CN201280066658.1A Pending CN104081401A (zh) | 2011-11-10 | 2012-11-12 | 用于对冠脉循环进行多尺度的解剖学和功能建模的方法和系统 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280066658.1A Pending CN104081401A (zh) | 2011-11-10 | 2012-11-12 | 用于对冠脉循环进行多尺度的解剖学和功能建模的方法和系统 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10162932B2 (enExample) |
| EP (1) | EP2776960B1 (enExample) |
| JP (1) | JP5980942B2 (enExample) |
| KR (1) | KR20140091741A (enExample) |
| CN (2) | CN110085321B (enExample) |
| BR (1) | BR112014011342A2 (enExample) |
| IN (1) | IN2014CN03423A (enExample) |
| WO (1) | WO2013071219A1 (enExample) |
Families Citing this family (136)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US8200466B2 (en) | 2008-07-21 | 2012-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Method for tuning patient-specific cardiovascular simulations |
| US9405886B2 (en) | 2009-03-17 | 2016-08-02 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining cardiovascular information |
| US8315812B2 (en) | 2010-08-12 | 2012-11-20 | Heartflow, Inc. | Method and system for patient-specific modeling of blood flow |
| US9119540B2 (en) | 2010-09-16 | 2015-09-01 | Siemens Aktiengesellschaft | Method and system for non-invasive assessment of coronary artery disease |
| FR2978345B1 (fr) | 2011-07-25 | 2013-08-30 | Charam Khosrovaninejad | Dispositif chirurgical d'ancrage controle dans l'intestin. |
| US8965084B2 (en) * | 2012-01-19 | 2015-02-24 | Siemens Aktiengesellschaft | Blood flow computation in vessels with implanted devices |
| US9183763B2 (en) * | 2012-01-31 | 2015-11-10 | Vascular Simulations, Llc | Cardiac simulation device |
| US10229615B2 (en) | 2012-01-31 | 2019-03-12 | Vascular Simulations Inc. | Cardiac simulation device |
| US10034614B2 (en) * | 2012-02-29 | 2018-07-31 | General Electric Company | Fractional flow reserve estimation |
| JP5946127B2 (ja) | 2012-05-11 | 2016-07-05 | 富士通株式会社 | シミュレーション方法、シミュレーション装置、およびシミュレーションプログラム |
| US8548778B1 (en) * | 2012-05-14 | 2013-10-01 | Heartflow, Inc. | Method and system for providing information from a patient-specific model of blood flow |
| US9247918B2 (en) | 2012-07-09 | 2016-02-02 | Siemens Aktiengesellschaft | Computation of hemodynamic quantities from angiographic data |
| GB2519909A (en) * | 2012-08-10 | 2015-05-06 | Vita Sentry Ltd | Estimations of equivalent inner diameter of arterioles |
| US10433740B2 (en) | 2012-09-12 | 2019-10-08 | Heartflow, Inc. | Systems and methods for estimating ischemia and blood flow characteristics from vessel geometry and physiology |
| US10398386B2 (en) | 2012-09-12 | 2019-09-03 | Heartflow, Inc. | Systems and methods for estimating blood flow characteristics from vessel geometry and physiology |
| EP2943902B1 (en) | 2012-10-24 | 2020-03-11 | CathWorks Ltd. | Automated measurement system and method for coronary artery disease scoring |
| US9858387B2 (en) * | 2013-01-15 | 2018-01-02 | CathWorks, LTD. | Vascular flow assessment |
| US10595807B2 (en) | 2012-10-24 | 2020-03-24 | Cathworks Ltd | Calculating a fractional flow reserve |
| US10210956B2 (en) | 2012-10-24 | 2019-02-19 | Cathworks Ltd. | Diagnostically useful results in real time |
| JP6358590B2 (ja) * | 2013-08-09 | 2018-07-18 | 富士通株式会社 | 血管データ生成装置、血管データ生成方法、および血管データ生成プログラム |
| US9805463B2 (en) * | 2013-08-27 | 2017-10-31 | Heartflow, Inc. | Systems and methods for predicting location, onset, and/or change of coronary lesions |
| US9462954B2 (en) * | 2013-09-04 | 2016-10-11 | Siemens Aktiengesellschaft | Method and system for blood flow velocity reconstruction from medical images |
| JP6297699B2 (ja) * | 2013-09-06 | 2018-03-20 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | 心臓データを処理する処理装置、そのような処理装置を有するイメージングシステム、処理装置の作動方法、イメージングシステムの作動方法及びコンピュータプログラム |
| US10595806B2 (en) * | 2013-10-22 | 2020-03-24 | Koninklijke Philips N.V. | Fractional flow reserve (FFR) index with adaptive boundary condition parameters |
| US9092743B2 (en) | 2013-10-23 | 2015-07-28 | Stenomics, Inc. | Machine learning system for assessing heart valves and surrounding cardiovascular tracts |
| EP3954298A3 (en) | 2013-10-24 | 2022-03-16 | Cathworks Ltd. | Vascular characteristic determination with correspondence modeling of a vascular tree |
| EP3066597A1 (en) | 2013-11-08 | 2016-09-14 | Piskin, Senol | Operation scenario flow and mechanical modeling and analysis system of cardiovascular repair operations for newborn and foetus |
| CN105792738B (zh) * | 2013-12-04 | 2020-03-13 | 皇家飞利浦有限公司 | 用于改善功能狭窄分析的局部ffr估计和可视化 |
| US9220418B2 (en) * | 2013-12-18 | 2015-12-29 | Heartflow, Inc. | Systems and methods for predicting coronary plaque vulnerability from patient-specific anatomic image data |
| US20170169609A1 (en) * | 2014-02-19 | 2017-06-15 | Koninklijke Philips N.V. | Motion adaptive visualization in medical 4d imaging |
| JP6262027B2 (ja) | 2014-03-10 | 2018-01-17 | 東芝メディカルシステムズ株式会社 | 医用画像処理装置 |
| JP2015171486A (ja) * | 2014-03-12 | 2015-10-01 | 国立大学法人大阪大学 | 血流解析システムおよび血流解析プログラム |
| US9390232B2 (en) * | 2014-03-24 | 2016-07-12 | Heartflow, Inc. | Systems and methods for modeling changes in patient-specific blood vessel geometry and boundary conditions |
| US9785746B2 (en) * | 2014-03-31 | 2017-10-10 | Heartflow, Inc. | Systems and methods for determining blood flow characteristics using flow ratio |
| US10354349B2 (en) | 2014-04-01 | 2019-07-16 | Heartflow, Inc. | Systems and methods for using geometry sensitivity information for guiding workflow |
| US9773219B2 (en) * | 2014-04-01 | 2017-09-26 | Heartflow, Inc. | Systems and methods for using geometry sensitivity information for guiding workflow |
| US9595089B2 (en) | 2014-05-09 | 2017-03-14 | Siemens Healthcare Gmbh | Method and system for non-invasive computation of hemodynamic indices for coronary artery stenosis |
| JP2015217113A (ja) * | 2014-05-16 | 2015-12-07 | 株式会社東芝 | 血管解析装置、医用画像診断装置、血管解析方法及び血管解析プログラム |
| US10130266B2 (en) | 2014-06-30 | 2018-11-20 | Siemens Healthcare Gmbh | Method and system for prediction of post-stenting hemodynamic metrics for treatment planning of arterial stenosis |
| EP3160335B1 (en) * | 2014-06-30 | 2023-09-20 | Koninklijke Philips N.V. | Apparatus for determining a fractional flow reserve value |
| US9888968B2 (en) * | 2014-07-22 | 2018-02-13 | Siemens Healthcare Gmbh | Method and system for automated therapy planning for arterial stenosis |
| US9195801B1 (en) * | 2014-08-05 | 2015-11-24 | Heartflow, Inc. | Systems and methods for treatment planning based on plaque progression and regression curves |
| US9594876B2 (en) | 2014-11-04 | 2017-03-14 | Heartflow, Inc. | Systems and methods for simulation of occluded arteries and optimization of occlusion-based treatments |
| US9349178B1 (en) | 2014-11-24 | 2016-05-24 | Siemens Aktiengesellschaft | Synthetic data-driven hemodynamic determination in medical imaging |
| WO2016115206A1 (en) * | 2015-01-14 | 2016-07-21 | Heartflow, Inc. | Systems and methods for embolism prediction using embolus source and destination probabilities |
| DE102015202286A1 (de) | 2015-02-10 | 2016-08-11 | Siemens Healthcare Gmbh | Verfahren zur Erzeugung eines Fertigungsmodells für ein medizinisches Implantat |
| US10478130B2 (en) | 2015-02-13 | 2019-11-19 | Siemens Healthcare Gmbh | Plaque vulnerability assessment in medical imaging |
| EP3062248A1 (en) * | 2015-02-27 | 2016-08-31 | Pie Medical Imaging BV | Method and apparatus for quantitative flow analysis |
| WO2016164809A1 (en) * | 2015-04-10 | 2016-10-13 | Heartflow, Inc. | System and method for vascular tree generation using patient-specific structural and functional data, and joint prior information |
| CN107615335A (zh) * | 2015-05-12 | 2018-01-19 | 新加坡保健服务集团有限公司 | 医学图象处理方法和系统 |
| KR101977294B1 (ko) * | 2015-06-05 | 2019-05-10 | 서울대학교산학협력단 | 전산유체역학을 이용한 기관지 분석 방법 및 그 장치 |
| US10872698B2 (en) * | 2015-07-27 | 2020-12-22 | Siemens Healthcare Gmbh | Method and system for enhancing medical image-based blood flow computations using physiological measurements |
| WO2017021201A1 (en) | 2015-08-05 | 2017-02-09 | Koninklijke Philips N.V. | Assistance device and method for an interventional hemodynamic measurement |
| JP6818492B2 (ja) | 2015-10-05 | 2021-01-20 | キヤノンメディカルシステムズ株式会社 | 画像処理装置、画像処理方法、及びプログラム |
| WO2017060106A1 (en) * | 2015-10-07 | 2017-04-13 | Koninklijke Philips N.V. | Mobile ffr simulation |
| JP6484760B2 (ja) | 2015-11-05 | 2019-03-13 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | 非侵襲的血流予備量比（ｆｆｒ）に対する側副血流モデル化 |
| US10236084B2 (en) * | 2015-11-10 | 2019-03-19 | Heartflow, Inc. | Systems and methods for anatomical modeling using information obtained from a medical procedure |
| US10499990B2 (en) * | 2015-11-23 | 2019-12-10 | Heartflow, Inc. | Systems and methods for assessing organ and/or tissue transplantation by simulating one or more transplant characteristics |
| US11191490B2 (en) | 2015-12-02 | 2021-12-07 | Siemens Healthcare Gmbh | Personalized assessment of patients with acute coronary syndrome |
| KR101954272B1 (ko) * | 2016-01-28 | 2019-03-05 | 연세대학교 산학협력단 | 유체-구조 상호작용을 고려한 협착 병변 영역의 혈류역학 시뮬레이션 방법 |
| JP6829262B2 (ja) | 2016-02-26 | 2021-02-10 | ハートフロー， インコーポレイテッド | 画像ベースの患者固有の血流力学的モデルにおいて解像されていない血管を特定してモデル化するためのシステム及び方法 |
| DE102016203860A1 (de) * | 2016-03-09 | 2017-09-14 | Siemens Healthcare Gmbh | Vorrichtung und Verfahren zum Ermitteln zumindest eines individuellen fluiddynamischen Kennwerts einer Stenose in einem mehrere serielle Stenosen aufweisenden Gefäßsegment |
| US10971271B2 (en) * | 2016-04-12 | 2021-04-06 | Siemens Healthcare Gmbh | Method and system for personalized blood flow modeling based on wearable sensor networks |
| JP7036742B2 (ja) | 2016-05-16 | 2022-03-15 | キャスワークス リミテッド | 血管評価システム |
| IL263066B2 (en) | 2016-05-16 | 2023-09-01 | Cathworks Ltd | Selecting blood vessels from images |
| CN106073894B (zh) * | 2016-05-31 | 2017-08-08 | 博动医学影像科技（上海）有限公司 | 基于植入虚拟支架的血管压力降数值及血流储备分数的评估方法和系统 |
| CN109863501B (zh) * | 2016-07-22 | 2022-12-27 | 康奈尔大学 | 针对患者定制的冠状动脉旁路移植物的快速成型和体外建模 |
| US11298104B2 (en) * | 2016-08-10 | 2022-04-12 | Canon Medical Systems Corporation | Medical processing apparatus, ultrasound diagnostic apparatus, and medical processing method |
| CN106308838B (zh) * | 2016-08-29 | 2019-06-07 | 于洋 | 一种ct图像处理装置 |
| CN109688908B (zh) * | 2016-09-16 | 2023-01-03 | 皇家飞利浦有限公司 | 用于确定血流储备分数的装置和方法 |
| EP3516561B1 (en) | 2016-09-20 | 2024-03-13 | HeartFlow, Inc. | Method, system and non-transitory computer-readable medium for estimation of blood flow characteristics using a reduced order model and machine learning |
| WO2018089413A1 (en) * | 2016-11-08 | 2018-05-17 | President And Fellows Of Harvard College | Methodology and apparatus for simulation of medical devices |
| CN106361429B (zh) * | 2016-11-10 | 2018-09-11 | 西安电子科技大学 | 借助3d打印实现先心病手术方案术前评估装置和方法 |
| WO2018108276A1 (en) * | 2016-12-15 | 2018-06-21 | Sintef Tto As | Method and process for providing a subject-specific computational model used for decision support and making diagnosis of cardiovascular diseases |
| CN106650272B (zh) * | 2016-12-28 | 2019-02-12 | 北京昆仑医云科技有限公司 | 个体特异性的心血管模型的生成方法及其应用 |
| EP4393386A3 (en) | 2017-01-23 | 2024-09-11 | Shanghai United Imaging Healthcare Co., Ltd. | Method and system for analyzing blood flow condition |
| JP7181216B2 (ja) * | 2017-03-31 | 2022-11-30 | コーニンクレッカ フィリップス エヌ ヴェ | 経カテーテル大動脈弁移植術（ｔａｖｉ）が冠血流量及び冠動脈圧に及ぼす影響のシミュレーション |
| US11710569B2 (en) | 2017-04-06 | 2023-07-25 | Koninklijke Philips N.V. | Coronary artery disease metric based on estimation of myocardial microvascular resistance from ECG signal |
| CN107411819B (zh) * | 2017-04-12 | 2021-08-10 | 上海大学 | 球囊血管成形手术过程实时模拟方法 |
| JP7232195B2 (ja) * | 2017-05-04 | 2023-03-02 | コーニンクレッカ フィリップス エヌ ヴェ | 血管内の壁せん断応力の同時視覚化及び定量化のためのシステム及び方法 |
| US10909676B2 (en) * | 2017-07-12 | 2021-02-02 | Siemens Healthcare Gmbh | Method and system for clinical decision support with local and remote analytics |
| CN110998744B (zh) | 2017-08-01 | 2024-04-05 | 西门子医疗有限公司 | 针对弥漫性和串联性病变中冠状动脉疾病的非侵入性评估和治疗指导 |
| EP3691531A4 (en) * | 2017-10-06 | 2021-05-26 | Emory University | METHODS AND SYSTEMS FOR DETERMINING HEMODYNAMIC INFORMATION FOR ONE OR MORE ARTERIAL SEGMENTS |
| EP3494893A1 (en) | 2017-12-05 | 2019-06-12 | Koninklijke Philips N.V. | Ultrasound imaging system and method |
| FR3072557B1 (fr) | 2017-10-19 | 2019-11-08 | Safeheal | Dispositif chirurgical complexe pour la realisation et protection d'une anastomose. |
| US11605447B2 (en) | 2017-10-27 | 2023-03-14 | Siemens Healthcare Gmbh | Intelligent agents for patient management |
| EP3489893B1 (en) | 2017-11-22 | 2020-06-24 | Siemens Healthcare GmbH | Method and system for assessing a haemodynamic parameter |
| JP6530043B2 (ja) * | 2017-12-12 | 2019-06-12 | キヤノンメディカルシステムズ株式会社 | 医用画像処理装置、医用画像処理方法および記録媒体 |
| WO2019173830A1 (en) | 2018-03-09 | 2019-09-12 | Emory University | Methods and systems for determining coronary hemodynamic characteristic(s) that is predictive of myocardial infarction |
| US11389130B2 (en) | 2018-05-02 | 2022-07-19 | Siemens Healthcare Gmbh | System and methods for fast computation of computed tomography based fractional flow reserve |
| US12100516B2 (en) * | 2018-05-31 | 2024-09-24 | Corflow Therapeutics Ag | Microfluidic coronary circulatory model |
| US11083377B2 (en) * | 2018-06-15 | 2021-08-10 | Pie Medical Imaging B.V. | Method and apparatus for quantitative hemodynamic flow analysis |
| KR102078622B1 (ko) * | 2018-06-28 | 2020-04-07 | 연세대학교 산학협력단 | 협착 병변의 수학적 모델링을 이용한 심혈관 정보 결정 방법 |
| KR102189311B1 (ko) * | 2018-08-21 | 2020-12-09 | 두산중공업 주식회사 | 학습된 모델을 이용한 해석 장치 및 이를 위한 방법 |
| KR102138227B1 (ko) * | 2018-08-21 | 2020-07-27 | 두산중공업 주식회사 | 유동 해석을 최적화하기 위한 장치 및 이를 위한 방법 |
| EP3613351A1 (en) * | 2018-08-22 | 2020-02-26 | Koninklijke Philips N.V. | Coronary circulation using intra-cardiac echo |
| GB201820044D0 (en) * | 2018-10-29 | 2019-01-23 | Univ Oxford Innovation Ltd | Radiomic signature of an epicardial region |
| WO2020061483A1 (en) | 2018-09-21 | 2020-03-26 | Vascular Simulations, Inc. | Cardiac simulation device |
| WO2020098705A1 (zh) * | 2018-11-13 | 2020-05-22 | 苏州润迈德医疗科技有限公司 | 基于造影图像获取静息态下血管评定参数的方法及装置 |
| US10964017B2 (en) * | 2018-11-15 | 2021-03-30 | General Electric Company | Deep learning for arterial analysis and assessment |
| JP7233209B2 (ja) * | 2018-12-03 | 2023-03-06 | 朝日インテック株式会社 | 心臓シミュレータ |
| EP3671494A1 (en) * | 2018-12-21 | 2020-06-24 | Dassault Systèmes | Multi-instanced simulations for large environments |
| CN109700574B (zh) * | 2018-12-21 | 2021-01-05 | 北京工业大学 | 一种基于ct影像数据制备钙化主动脉瓣的方法 |
| CN109700475B (zh) * | 2018-12-27 | 2021-01-08 | 浙江大学 | 一种冠脉搭桥参数的确定方法、装置、设备和存储介质 |
| RS64846B1 (sr) * | 2019-01-11 | 2023-12-29 | Hemolens Diagnostics Spolka Z Ograniczona Odpowiedzialnoscia | Modelovanje hemodinamskih parametara u koronarnim arterijama specifično za pacijenta |
| CN109872336B (zh) * | 2019-03-13 | 2021-07-09 | 数坤(北京)网络科技股份有限公司 | 一种血管分割方法、设备及计算机存储介质 |
| JP7532402B2 (ja) | 2019-04-01 | 2024-08-13 | キャスワークス リミテッド | 血管造影画像選択のための方法および装置 |
| US10861157B2 (en) | 2019-04-04 | 2020-12-08 | Medtronic Vascular, Inc. | System and methods for determining modified fractional flow reserve values |
| US11357573B2 (en) | 2019-04-25 | 2022-06-14 | International Business Machines Corporation | Optimum treatment planning during coronary intervention by simultaneous simulation of a continuum of outcomes |
| JP6751178B2 (ja) * | 2019-05-14 | 2020-09-02 | キヤノンメディカルシステムズ株式会社 | 医用画像処理装置、医用画像処理方法および記録媒体 |
| CN110368087B (zh) * | 2019-06-06 | 2021-01-08 | 中国人民解放军北部战区总医院 | 一种信息处理方法和装置、及可读存储介质 |
| CN110310744B (zh) * | 2019-06-10 | 2021-12-24 | 暨南大学 | 窦房结虚拟生理组织的构建方法、存储介质和计算设备 |
| EP4033964B1 (en) | 2019-09-23 | 2025-04-09 | Cathworks Ltd. | Methods, apparatus, and system for synchronization between a three-dimensional vascular model and an imaging device |
| KR102130254B1 (ko) * | 2019-10-15 | 2020-07-03 | 주식회사 실리콘사피엔스 | 대상자 고유의 혈관에 대한 혈류 시뮬레이션 방법 및 장치 |
| US11026749B1 (en) | 2019-12-05 | 2021-06-08 | Board Of Regents Of The University Of Nebraska | Computational simulation platform for planning of interventional procedures |
| US12096986B2 (en) | 2019-12-05 | 2024-09-24 | The Board Of Regents Of The University Of Nebraska | Computational simulation platform for planning of interventional procedures |
| CN111241759B (zh) * | 2020-01-13 | 2024-03-26 | 北京工业大学 | 一种基于零维血流动力学模型的ffr快速计算方法 |
| DE102020200750A1 (de) * | 2020-01-22 | 2021-07-22 | Siemens Healthcare Gmbh | Bereitstellen eines Blutflussparametersatzes einer Gefäßmalformation |
| CN111317455B (zh) | 2020-03-03 | 2022-02-22 | 上海联影医疗科技股份有限公司 | 血流动力学参数确定方法、装置、设备及存储介质 |
| CN111616678B (zh) * | 2020-04-17 | 2023-04-14 | 清华大学 | 一种基于智能冠状动脉支架的再狭窄监测装置及方法 |
| US11538153B2 (en) * | 2020-08-31 | 2022-12-27 | Huidan Yu | Non-invasive functional assessment technique for determining hemodynamic severity of an arterial stenosis |
| CN112617791B (zh) * | 2020-12-22 | 2022-09-20 | 杭州晟视科技有限公司 | 一种模拟血管搏动的方法、装置及存储介质 |
| WO2022136688A1 (en) * | 2020-12-23 | 2022-06-30 | Flowreserve Labs S.L. | Non-invasive method for determining a vessel damage indicator |
| CN112950537A (zh) * | 2021-01-26 | 2021-06-11 | 上海友脉科技有限责任公司 | 一种冠脉血流储备分数获取系统、方法及介质 |
| WO2022250975A1 (en) * | 2021-05-27 | 2022-12-01 | Board Of Regents Of The University Of Nebraska | Patient-specific computational simulation of coronary artery bypass grafting |
| CN113658701B (zh) * | 2021-08-26 | 2024-08-23 | 上海联影医疗科技股份有限公司 | 术后评估方法、计算机设备和存储介质 |
| CN113648059B (zh) * | 2021-08-26 | 2023-09-29 | 上海联影医疗科技股份有限公司 | 手术规划评估方法、计算机设备和存储介质 |
| US12315076B1 (en) | 2021-09-22 | 2025-05-27 | Cathworks Ltd. | Four-dimensional motion analysis of a patient's coronary arteries and myocardial wall |
| US12387325B2 (en) | 2022-02-10 | 2025-08-12 | Cath Works Ltd. | System and method for machine-learning based sensor analysis and vascular tree segmentation |
| CN115115735B (zh) * | 2022-06-29 | 2024-07-23 | 温州医科大学附属第二医院（温州医科大学附属育英儿童医院） | 一种基于多期相冠脉ct造影的内皮动应变的快速计算系统 |
| EP4410212A1 (en) * | 2023-02-02 | 2024-08-07 | Koninklijke Philips N.V. | Vascular diagnostic apparatus and method |
| US12213673B2 (en) | 2023-03-17 | 2025-02-04 | SafeHeal SAS | Systems and methods for introducing and monitoring a negative pressure device for protecting an intestinal anastomosis |
| US12446965B2 (en) | 2023-08-09 | 2025-10-21 | Cathworks Ltd. | Enhanced user interface and crosstalk analysis for vascular index measurement |
| WO2025214321A1 (zh) * | 2024-04-07 | 2025-10-16 | 深圳迈瑞生物医疗电子股份有限公司 | 一种目标部位的病变模型生成方法及装置 |
| US20250384979A1 (en) | 2024-06-12 | 2025-12-18 | Cathworks Ltd. | Systems and methods for secure sharing of cardiac assessments using qr codes |
| CN119786054A (zh) * | 2024-12-26 | 2025-04-08 | 中国科学院深圳先进技术研究院 | 一种血流数值模拟方法、装置、计算机设备及存储介质 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1914617A (zh) * | 2004-02-03 | 2007-02-14 | 美国西门子医疗解决公司 | 与心脏有关的疾病和病症的自动诊断和决策支持系统和方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10026666A1 (de) | 2000-05-29 | 2001-12-20 | Gunther Burgard | Verwendung von Hyaluronidase zur Prophylaxe und Behandlung von Herz-Kreislauf-Erkrankungen |
| JP5481069B2 (ja) | 2005-12-20 | 2014-04-23 | コーニンクレッカ フィリップス エヌ ヴェ | 対象物の少なくとも一部を細かく再現したものを再構成する再構成ユニット |
| US7860290B2 (en) | 2006-04-21 | 2010-12-28 | Siemens Medical Solutions Usa, Inc. | Three-dimensional (3D) modeling of coronary arteries |
| US7953266B2 (en) | 2007-02-06 | 2011-05-31 | Siemens Medical Solutions Usa, Inc. | Robust vessel tree modeling |
| US8098918B2 (en) | 2007-09-21 | 2012-01-17 | Siemens Corporation | Method and system for measuring left ventricle volume |
| WO2009064715A1 (en) | 2007-11-14 | 2009-05-22 | Auckland Uniservices Limited | Method for multi-scale meshing of branching biological structures |
| EP2252953A1 (en) * | 2008-02-04 | 2010-11-24 | Iain Alexander Anderson | Integrated-model musculoskeletal therapies |
| US9427173B2 (en) * | 2008-05-09 | 2016-08-30 | General Electric Company | Determining mechanical force on aneurysms from a fluid dynamic model driven by vessel blood flow information |
| JP5089514B2 (ja) | 2008-07-11 | 2012-12-05 | キヤノン株式会社 | 撮像装置、及び撮像システム |
| US8200466B2 (en) | 2008-07-21 | 2012-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Method for tuning patient-specific cardiovascular simulations |
| US8582854B2 (en) * | 2008-09-15 | 2013-11-12 | Siemens Aktiengesellschaft | Method and system for automatic coronary artery detection |
| US9405996B2 (en) * | 2008-09-18 | 2016-08-02 | Siemens Aktiengesellschaft | Method and system for generating a personalized anatomical heart model |
| US9405886B2 (en) | 2009-03-17 | 2016-08-02 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining cardiovascular information |
| US9715637B2 (en) | 2009-03-18 | 2017-07-25 | Siemens Healthcare Gmbh | Method and system for automatic aorta segmentation |
| US8224640B2 (en) | 2009-09-08 | 2012-07-17 | Siemens Aktiengesellschaft | Method and system for computational modeling of the aorta and heart |
| JP5721721B2 (ja) | 2009-09-23 | 2015-05-20 | ライトラボ・イメージング・インコーポレーテッド | 管腔形態および血管抵抗測定データ収集のシステム、装置および方法 |
| US8526699B2 (en) | 2010-03-12 | 2013-09-03 | Siemens Aktiengesellschaft | Method and system for automatic detection and classification of coronary stenoses in cardiac CT volumes |
| US20110270051A1 (en) * | 2010-05-03 | 2011-11-03 | Morteza Naghavi | Cardiovascular Disease Screening Method and Apparatus |
| US8682626B2 (en) | 2010-07-21 | 2014-03-25 | Siemens Aktiengesellschaft | Method and system for comprehensive patient-specific modeling of the heart |
| US8157742B2 (en) | 2010-08-12 | 2012-04-17 | Heartflow, Inc. | Method and system for patient-specific modeling of blood flow |
| US8315812B2 (en) | 2010-08-12 | 2012-11-20 | Heartflow, Inc. | Method and system for patient-specific modeling of blood flow |
| DE102010039312B4 (de) | 2010-08-13 | 2020-02-13 | Siemens Healthcare Gmbh | Verfahren zur Simulation eines Blutflusses |
| US9119540B2 (en) | 2010-09-16 | 2015-09-01 | Siemens Aktiengesellschaft | Method and system for non-invasive assessment of coronary artery disease |
| DE102010043849B3 (de) | 2010-11-12 | 2012-02-16 | Siemens Aktiengesellschaft | Vorrichtung und Computertomograph zur Bestimmung und Darstellung der Durchblutung des Herzmuskels |
| US9141763B2 (en) | 2011-02-07 | 2015-09-22 | Siemens Aktiengesellschaft | Method and system for patient-specific computational modeling and simulation for coupled hemodynamic analysis of cerebral vessels |
-
2012
- 2012-11-09 US US13/672,781 patent/US10162932B2/en active Active
- 2012-11-12 JP JP2014541362A patent/JP5980942B2/ja active Active
- 2012-11-12 CN CN201910202025.2A patent/CN110085321B/zh active Active
- 2012-11-12 IN IN3423CHN2014 patent/IN2014CN03423A/en unknown
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1914617A (zh) * | 2004-02-03 | 2007-02-14 | 美国西门子医疗解决公司 | 与心脏有关的疾病和病症的自动诊断和决策支持系统和方法 |
Non-Patent Citations (4)
| Title |
|---|
| Alterations in regional vascular geometry produced by theoretical stent implantation influence distributions of wall shear stress:analysis of a curved coronary artery using 3D computational fluid dynamics modeling;John F LaDisa等;《BioMedical Engineering Online20065:40》;20060616;第1-11页 * |
| Multiscale modelling of the circulatory system：A preliminary analysis;Luca Formaggia等;《Computering and visualization in science》;19991231;第75-83页 * |
| Patient-specific modeling of blood flow and pressure in human coronary arteries;H.J.Kim等;《Annals of Biomedical Engineering》;20101031;第3195-3209页 * |
| 冠状与系统循环血动力学关系的模型研究;郑泰胜;中国生物医学工程学报(第02期);全文 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20130132054A1 (en) | 2013-05-23 |
| CN110085321A (zh) | 2019-08-02 |
| EP2776960B1 (en) | 2021-09-01 |
| CN104081401A (zh) | 2014-10-01 |
| US10162932B2 (en) | 2018-12-25 |
| BR112014011342A2 (pt) | 2017-05-02 |
| JP2014534889A (ja) | 2014-12-25 |
| IN2014CN03423A (enExample) | 2015-07-03 |
| JP5980942B2 (ja) | 2016-08-31 |
| WO2013071219A1 (en) | 2013-05-16 |
| EP2776960A1 (en) | 2014-09-17 |
| KR20140091741A (ko) | 2014-07-22 |
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