BR112014011342A2 - método e sistema de modelagem anatômica e funcional multiescala de circulação coronária - Google Patents

método e sistema de modelagem anatômica e funcional multiescala de circulação coronária

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Publication number
BR112014011342A2
BR112014011342A2 BR112014011342A BR112014011342A BR112014011342A2 BR 112014011342 A2 BR112014011342 A2 BR 112014011342A2 BR 112014011342 A BR112014011342 A BR 112014011342A BR 112014011342 A BR112014011342 A BR 112014011342A BR 112014011342 A2 BR112014011342 A2 BR 112014011342A2
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Brazil
Prior art keywords
functional
model
coronary circulation
multiscale
coronary
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BR112014011342A
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English (en)
Inventor
Kamen Ali
Georgescu Bogdan
Comaniciu Dorin
Mihai Itu Lucian
Sharma Puneet
Mihalef Viorel
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Siemens Corp
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Application filed by Siemens Corp filed Critical Siemens Corp
Publication of BR112014011342A2 publication Critical patent/BR112014011342A2/pt

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    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
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    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C10/00—Computational theoretical chemistry, i.e. ICT specially adapted for theoretical aspects of quantum chemistry, molecular mechanics, molecular dynamics or the like
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    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
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    • G16C20/30—Prediction of properties of chemical compounds, compositions or mixtures
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    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/40—Searching chemical structures or physicochemical data
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C99/00—Subject matter not provided for in other groups of this subclass
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/20—ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biomedical Technology (AREA)
  • Data Mining & Analysis (AREA)
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  • Databases & Information Systems (AREA)
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  • Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

abstract: method and system for multi-scale anatomical and functional modeling of coronary circulation is disclosed. a patient-specific anatomical model of coronary arteries and the heart is generated from medical image data of a patient. a multi-scale functional model of coronary circulation is generated based on the patient-specific anatomical model. blood flow is simulated in at least one stenosis region of at least one coronary artery using the multi-scale function model of coronary circulation. hemodynamic quantities, such as fractional flow reserve (ffr), are computed to determine a functional assessment of the stenosis, and virtual intervention simulations are performed using the multi-scale function model of coronary circulation for decision support and intervention planning. tradução do resumo resumo patente de invenção: "método e sistema de modelagem anatômica e funcional multiescala de circulação coronária". trata-se de um método e sistema de modelagem anatômica e funcional multiescala de circulação coronária. um modelo anatômico específico de paciente de artérias coronárias e do coração é gerado a partir dos dados de imagem médicos de um paciente. um modelo funcional multiescala de circulação coronária é gerado com base no modelo anatômico específico de paciente. o fluxo sanguíneo é simulado em pelo menos uma região de estenose de pelo menos uma artéria coronária utilizando o modelo funcional multiescala de circulação coronária. as quantidades hemodinâmicas, como reserva de fluxo fracionada (ffr), são computadas para determinar uma avaliação funcional da estenose, e simulações de intervenção virtual são realizadas utilizando o modelo funcional multiescala de circulação coronária para o apoio à decisão e planejamento de intervenção.
BR112014011342A 2011-11-10 2012-11-12 método e sistema de modelagem anatômica e funcional multiescala de circulação coronária BR112014011342A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161557935P 2011-11-10 2011-11-10
US13/672,781 US10162932B2 (en) 2011-11-10 2012-11-09 Method and system for multi-scale anatomical and functional modeling of coronary circulation
PCT/US2012/064604 WO2013071219A1 (en) 2011-11-10 2012-11-12 Method and system for multi-scale anatomical and functional modeling of coronary circulation

Publications (1)

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BR112014011342A2 true BR112014011342A2 (pt) 2017-05-02

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BR112014011342A BR112014011342A2 (pt) 2011-11-10 2012-11-12 método e sistema de modelagem anatômica e funcional multiescala de circulação coronária

Country Status (8)

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US (1) US10162932B2 (pt)
EP (1) EP2776960B1 (pt)
JP (1) JP5980942B2 (pt)
KR (1) KR20140091741A (pt)
CN (2) CN104081401A (pt)
BR (1) BR112014011342A2 (pt)
IN (1) IN2014CN03423A (pt)
WO (1) WO2013071219A1 (pt)

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