BR112014011342A2 - método e sistema de modelagem anatômica e funcional multiescala de circulação coronária - Google Patents

método e sistema de modelagem anatômica e funcional multiescala de circulação coronária

Info

Publication number
BR112014011342A2
BR112014011342A2 BR112014011342A BR112014011342A BR112014011342A2 BR 112014011342 A2 BR112014011342 A2 BR 112014011342A2 BR 112014011342 A BR112014011342 A BR 112014011342A BR 112014011342 A BR112014011342 A BR 112014011342A BR 112014011342 A2 BR112014011342 A2 BR 112014011342A2
Authority
BR
Brazil
Prior art keywords
functional
model
coronary circulation
multiscale
coronary
Prior art date
Application number
BR112014011342A
Other languages
English (en)
Inventor
Kamen Ali
Georgescu Bogdan
Comaniciu Dorin
Mihai Itu Lucian
Sharma Puneet
Mihalef Viorel
Original Assignee
Siemens Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Corp filed Critical Siemens Corp
Publication of BR112014011342A2 publication Critical patent/BR112014011342A2/pt

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C10/00—Computational theoretical chemistry, i.e. ICT specially adapted for theoretical aspects of quantum chemistry, molecular mechanics, molecular dynamics or the like
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/30—Prediction of properties of chemical compounds, compositions or mixtures
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/40—Searching chemical structures or physicochemical data
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C99/00—Subject matter not provided for in other groups of this subclass
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
    • G16Z99/00—Subject matter not provided for in other main groups of this subclass
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/20—ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biomedical Technology (AREA)
  • Data Mining & Analysis (AREA)
  • Pathology (AREA)
  • Databases & Information Systems (AREA)
  • Computing Systems (AREA)
  • Evolutionary Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

abstract: method and system for multi-scale anatomical and functional modeling of coronary circulation is disclosed. a patient-specific anatomical model of coronary arteries and the heart is generated from medical image data of a patient. a multi-scale functional model of coronary circulation is generated based on the patient-specific anatomical model. blood flow is simulated in at least one stenosis region of at least one coronary artery using the multi-scale function model of coronary circulation. hemodynamic quantities, such as fractional flow reserve (ffr), are computed to determine a functional assessment of the stenosis, and virtual intervention simulations are performed using the multi-scale function model of coronary circulation for decision support and intervention planning. tradução do resumo resumo patente de invenção: "método e sistema de modelagem anatômica e funcional multiescala de circulação coronária". trata-se de um método e sistema de modelagem anatômica e funcional multiescala de circulação coronária. um modelo anatômico específico de paciente de artérias coronárias e do coração é gerado a partir dos dados de imagem médicos de um paciente. um modelo funcional multiescala de circulação coronária é gerado com base no modelo anatômico específico de paciente. o fluxo sanguíneo é simulado em pelo menos uma região de estenose de pelo menos uma artéria coronária utilizando o modelo funcional multiescala de circulação coronária. as quantidades hemodinâmicas, como reserva de fluxo fracionada (ffr), são computadas para determinar uma avaliação funcional da estenose, e simulações de intervenção virtual são realizadas utilizando o modelo funcional multiescala de circulação coronária para o apoio à decisão e planejamento de intervenção.
BR112014011342A 2011-11-10 2012-11-12 método e sistema de modelagem anatômica e funcional multiescala de circulação coronária BR112014011342A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161557935P 2011-11-10 2011-11-10
US13/672,781 US10162932B2 (en) 2011-11-10 2012-11-09 Method and system for multi-scale anatomical and functional modeling of coronary circulation
PCT/US2012/064604 WO2013071219A1 (en) 2011-11-10 2012-11-12 Method and system for multi-scale anatomical and functional modeling of coronary circulation

Publications (1)

Publication Number Publication Date
BR112014011342A2 true BR112014011342A2 (pt) 2017-05-02

Family

ID=47279046

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014011342A BR112014011342A2 (pt) 2011-11-10 2012-11-12 método e sistema de modelagem anatômica e funcional multiescala de circulação coronária

Country Status (8)

Country Link
US (1) US10162932B2 (pt)
EP (1) EP2776960B1 (pt)
JP (1) JP5980942B2 (pt)
KR (1) KR20140091741A (pt)
CN (2) CN104081401A (pt)
BR (1) BR112014011342A2 (pt)
IN (1) IN2014CN03423A (pt)
WO (1) WO2013071219A1 (pt)

Families Citing this family (120)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8200466B2 (en) 2008-07-21 2012-06-12 The Board Of Trustees Of The Leland Stanford Junior University Method for tuning patient-specific cardiovascular simulations
US9405886B2 (en) 2009-03-17 2016-08-02 The Board Of Trustees Of The Leland Stanford Junior University Method for determining cardiovascular information
US8315812B2 (en) 2010-08-12 2012-11-20 Heartflow, Inc. Method and system for patient-specific modeling of blood flow
US9119540B2 (en) * 2010-09-16 2015-09-01 Siemens Aktiengesellschaft Method and system for non-invasive assessment of coronary artery disease
US8965084B2 (en) * 2012-01-19 2015-02-24 Siemens Aktiengesellschaft Blood flow computation in vessels with implanted devices
US10229615B2 (en) 2012-01-31 2019-03-12 Vascular Simulations Inc. Cardiac simulation device
US9183763B2 (en) * 2012-01-31 2015-11-10 Vascular Simulations, Llc Cardiac simulation device
US10034614B2 (en) * 2012-02-29 2018-07-31 General Electric Company Fractional flow reserve estimation
JP5946127B2 (ja) 2012-05-11 2016-07-05 富士通株式会社 シミュレーション方法、シミュレーション装置、およびシミュレーションプログラム
US8548778B1 (en) * 2012-05-14 2013-10-01 Heartflow, Inc. Method and system for providing information from a patient-specific model of blood flow
US9247918B2 (en) 2012-07-09 2016-02-02 Siemens Aktiengesellschaft Computation of hemodynamic quantities from angiographic data
GB2519909A (en) * 2012-08-10 2015-05-06 Vita Sentry Ltd Estimations of equivalent inner diameter of arterioles
US10433740B2 (en) 2012-09-12 2019-10-08 Heartflow, Inc. Systems and methods for estimating ischemia and blood flow characteristics from vessel geometry and physiology
US10398386B2 (en) 2012-09-12 2019-09-03 Heartflow, Inc. Systems and methods for estimating blood flow characteristics from vessel geometry and physiology
US9858387B2 (en) 2013-01-15 2018-01-02 CathWorks, LTD. Vascular flow assessment
US10210956B2 (en) 2012-10-24 2019-02-19 Cathworks Ltd. Diagnostically useful results in real time
US10595807B2 (en) 2012-10-24 2020-03-24 Cathworks Ltd Calculating a fractional flow reserve
EP2943902B1 (en) 2012-10-24 2020-03-11 CathWorks Ltd. Automated measurement system and method for coronary artery disease scoring
JP6358590B2 (ja) * 2013-08-09 2018-07-18 富士通株式会社 血管データ生成装置、血管データ生成方法、および血管データ生成プログラム
US9805463B2 (en) * 2013-08-27 2017-10-31 Heartflow, Inc. Systems and methods for predicting location, onset, and/or change of coronary lesions
US9462954B2 (en) * 2013-09-04 2016-10-11 Siemens Aktiengesellschaft Method and system for blood flow velocity reconstruction from medical images
JP6297699B2 (ja) * 2013-09-06 2018-03-20 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 心臓データを処理する処理装置、そのような処理装置を有するイメージングシステム、処理装置の作動方法、イメージングシステムの作動方法及びコンピュータプログラム
US10595806B2 (en) 2013-10-22 2020-03-24 Koninklijke Philips N.V. Fractional flow reserve (FFR) index with adaptive boundary condition parameters
US9092743B2 (en) 2013-10-23 2015-07-28 Stenomics, Inc. Machine learning system for assessing heart valves and surrounding cardiovascular tracts
US10424063B2 (en) 2013-10-24 2019-09-24 CathWorks, LTD. Vascular characteristic determination with correspondence modeling of a vascular tree
WO2015069202A1 (en) * 2013-11-08 2015-05-14 Piskin Senol Operation scenario flow and mechanical modeling and analysis system of cardiovascular repair operations for newborn and foetus
EP3076854B1 (en) * 2013-12-04 2022-04-20 Koninklijke Philips N.V. Local ffr estimation and visualisation for improved functional stenosis analysis
US9155512B2 (en) * 2013-12-18 2015-10-13 Heartflow, Inc. Systems and methods for predicting coronary plaque vulnerability from patient-specific anatomic image data
WO2015124388A1 (en) * 2014-02-19 2015-08-27 Koninklijke Philips N.V. Motion adaptive visualization in medical 4d imaging
JP6262027B2 (ja) 2014-03-10 2018-01-17 東芝メディカルシステムズ株式会社 医用画像処理装置
JP2015171486A (ja) * 2014-03-12 2015-10-01 国立大学法人大阪大学 血流解析システムおよび血流解析プログラム
US9390232B2 (en) * 2014-03-24 2016-07-12 Heartflow, Inc. Systems and methods for modeling changes in patient-specific blood vessel geometry and boundary conditions
US9785746B2 (en) * 2014-03-31 2017-10-10 Heartflow, Inc. Systems and methods for determining blood flow characteristics using flow ratio
US10354349B2 (en) 2014-04-01 2019-07-16 Heartflow, Inc. Systems and methods for using geometry sensitivity information for guiding workflow
US9773219B2 (en) 2014-04-01 2017-09-26 Heartflow, Inc. Systems and methods for using geometry sensitivity information for guiding workflow
US9595089B2 (en) * 2014-05-09 2017-03-14 Siemens Healthcare Gmbh Method and system for non-invasive computation of hemodynamic indices for coronary artery stenosis
JP2015217113A (ja) * 2014-05-16 2015-12-07 株式会社東芝 血管解析装置、医用画像診断装置、血管解析方法及び血管解析プログラム
CN106659400B (zh) * 2014-06-30 2021-01-05 皇家飞利浦有限公司 用于确定血流储备分数值的装置
US10130266B2 (en) 2014-06-30 2018-11-20 Siemens Healthcare Gmbh Method and system for prediction of post-stenting hemodynamic metrics for treatment planning of arterial stenosis
US9888968B2 (en) * 2014-07-22 2018-02-13 Siemens Healthcare Gmbh Method and system for automated therapy planning for arterial stenosis
US9195801B1 (en) 2014-08-05 2015-11-24 Heartflow, Inc. Systems and methods for treatment planning based on plaque progression and regression curves
US9594876B2 (en) 2014-11-04 2017-03-14 Heartflow, Inc. Systems and methods for simulation of occluded arteries and optimization of occlusion-based treatments
US9349178B1 (en) 2014-11-24 2016-05-24 Siemens Aktiengesellschaft Synthetic data-driven hemodynamic determination in medical imaging
WO2016115206A1 (en) * 2015-01-14 2016-07-21 Heartflow, Inc. Systems and methods for embolism prediction using embolus source and destination probabilities
DE102015202286A1 (de) * 2015-02-10 2016-08-11 Siemens Healthcare Gmbh Verfahren zur Erzeugung eines Fertigungsmodells für ein medizinisches Implantat
US10478130B2 (en) 2015-02-13 2019-11-19 Siemens Healthcare Gmbh Plaque vulnerability assessment in medical imaging
EP3062248A1 (en) * 2015-02-27 2016-08-31 Pie Medical Imaging BV Method and apparatus for quantitative flow analysis
EP3281135B1 (en) * 2015-04-10 2021-08-18 HeartFlow, Inc. System and method for vascular tree generation using patient-specific structural and functional data, and joint prior information
CN107615335A (zh) * 2015-05-12 2018-01-19 新加坡保健服务集团有限公司 医学图象处理方法和系统
KR101977294B1 (ko) * 2015-06-05 2019-05-10 서울대학교산학협력단 전산유체역학을 이용한 기관지 분석 방법 및 그 장치
US10872698B2 (en) * 2015-07-27 2020-12-22 Siemens Healthcare Gmbh Method and system for enhancing medical image-based blood flow computations using physiological measurements
WO2017021201A1 (en) 2015-08-05 2017-02-09 Koninklijke Philips N.V. Assistance device and method for an interventional hemodynamic measurement
JP6818492B2 (ja) 2015-10-05 2021-01-20 キヤノンメディカルシステムズ株式会社 画像処理装置、画像処理方法、及びプログラム
EP3359041B1 (en) * 2015-10-07 2021-03-03 Koninklijke Philips N.V. Mobile ffr simulation
WO2017076620A1 (en) 2015-11-05 2017-05-11 Koninklijke Philips N.V. Collateral flow modelling for non-invasive fractional flow reserve (ffr)
JP6918794B2 (ja) * 2015-11-10 2021-08-11 ハートフロー， インコーポレイテッド 解剖モデリングシステム及びその作動方法
EP3380968B1 (en) 2015-11-23 2021-04-28 HeartFlow, Inc. Systems and methods for assessing organ and/or tissue transplantation by simulating one or more transplant characteristics
US11191490B2 (en) 2015-12-02 2021-12-07 Siemens Healthcare Gmbh Personalized assessment of patients with acute coronary syndrome
KR101954272B1 (ko) * 2016-01-28 2019-03-05 연세대학교 산학협력단 유체-구조 상호작용을 고려한 협착 병변 영역의 혈류역학 시뮬레이션 방법
EP3420483B1 (en) 2016-02-26 2020-07-22 HeartFlow, Inc. Systems and methods for identifying and modeling unresolved vessels in image-based patient-specific hemodynamic models
DE102016203860A1 (de) * 2016-03-09 2017-09-14 Siemens Healthcare Gmbh Vorrichtung und Verfahren zum Ermitteln zumindest eines individuellen fluiddynamischen Kennwerts einer Stenose in einem mehrere serielle Stenosen aufweisenden Gefäßsegment
US10971271B2 (en) * 2016-04-12 2021-04-06 Siemens Healthcare Gmbh Method and system for personalized blood flow modeling based on wearable sensor networks
WO2017199246A1 (en) 2016-05-16 2017-11-23 Cathworks Ltd. Vascular selection from images
IL263065B1 (en) 2016-05-16 2024-04-01 Cathworks Ltd Vascular evaluation system
CN106073894B (zh) * 2016-05-31 2017-08-08 博动医学影像科技（上海）有限公司 基于植入虚拟支架的血管压力降数值及血流储备分数的评估方法和系统
EP3488386A4 (en) * 2016-07-22 2020-02-19 Cornell University FAST PROTOTYPIZATION AND IN VITRO MODELING OF PATIENT-SPECIFIC CORONAL ARTERY BYPASS IMPLANTS
CN106308838B (zh) * 2016-08-29 2019-06-07 于洋 一种ct图像处理装置
CN109688908B (zh) * 2016-09-16 2023-01-03 皇家飞利浦有限公司 用于确定血流储备分数的装置和方法
AU2017332031B2 (en) 2016-09-20 2022-12-08 Heartflow, Inc. System and methods for estimation of blood flow characteristics using reduced order model and machine learning
WO2018089413A1 (en) * 2016-11-08 2018-05-17 President And Fellows Of Harvard College Methodology and apparatus for simulation of medical devices
CN106361429B (zh) * 2016-11-10 2018-09-11 西安电子科技大学 借助3d打印实现先心病手术方案术前评估装置和方法
JP7021224B2 (ja) * 2016-12-15 2022-02-16 シンテフ テーテーオー アクスイェ セルスカプ 心臓血管疾患の決定支援および診断のため使用される対象特異的計算モデルを提供する方法およびプロセス
CN108122616B (zh) * 2016-12-28 2020-12-25 北京昆仑医云科技有限公司 个体特异性的心血管模型的生成方法及其应用
EP3375364A4 (en) 2017-01-23 2019-01-23 Shanghai United Imaging Healthcare Co., Ltd. SYSTEM AND METHOD FOR ANALYZING THE STATUS OF BLOOD CIRCULATION
WO2018178381A1 (en) * 2017-03-31 2018-10-04 Koninklijke Philips N.V. Simulation of transcatheter aortic valve implantation (tavi) induced effects on coronary flow and pressure
WO2018184779A1 (en) 2017-04-06 2018-10-11 Koninklijke Philips N.V. Coronary artery disease metric based on estimation of myocardial microvascular resistance from ecg signal
CN107411819B (zh) * 2017-04-12 2021-08-10 上海大学 球囊血管成形手术过程实时模拟方法
EP3619716B1 (en) * 2017-05-04 2023-09-13 Koninklijke Philips N.V. System and method for concurrent visualization and quantification of wall shear stress in blood vessels
US10909676B2 (en) * 2017-07-12 2021-02-02 Siemens Healthcare Gmbh Method and system for clinical decision support with local and remote analytics
US11589924B2 (en) 2017-08-01 2023-02-28 Siemens Healthcare Gmbh Non-invasive assessment and therapy guidance for coronary artery disease in diffuse and tandem lesions
WO2019071249A1 (en) 2017-10-06 2019-04-11 Emory University METHODS AND SYSTEMS FOR DETERMINING HEMODYNAMIC INFORMATION FOR ONE OR MORE ARTERIAL SEGMENTS
EP3494893A1 (en) * 2017-12-05 2019-06-12 Koninklijke Philips N.V. Ultrasound imaging system and method
US11605447B2 (en) 2017-10-27 2023-03-14 Siemens Healthcare Gmbh Intelligent agents for patient management
EP3489893B1 (en) 2017-11-22 2020-06-24 Siemens Healthcare GmbH Method and system for assessing a haemodynamic parameter
JP6530043B2 (ja) * 2017-12-12 2019-06-12 キヤノンメディカルシステムズ株式会社 医用画像処理装置、医用画像処理方法および記録媒体
US11341645B2 (en) 2018-03-09 2022-05-24 Emory University Methods and systems for determining coronary hemodynamic characteristic(s) that is predictive of myocardial infarction
US11389130B2 (en) 2018-05-02 2022-07-19 Siemens Healthcare Gmbh System and methods for fast computation of computed tomography based fractional flow reserve
US20210366620A1 (en) * 2018-05-31 2021-11-25 Corflow Therapeutics Ag Microfluidic coronary circulatory model
WO2019238754A1 (en) * 2018-06-15 2019-12-19 Pie Medical Imaging Bv Method and apparatus for quantitative hemodynamic flow analysis
KR102078622B1 (ko) * 2018-06-28 2020-04-07 연세대학교 산학협력단 협착 병변의 수학적 모델링을 이용한 심혈관 정보 결정 방법
KR102138227B1 (ko) * 2018-08-21 2020-07-27 두산중공업 주식회사 유동 해석을 최적화하기 위한 장치 및 이를 위한 방법
KR102189311B1 (ko) * 2018-08-21 2020-12-09 두산중공업 주식회사 학습된 모델을 이용한 해석 장치 및 이를 위한 방법
EP3613351A1 (en) * 2018-08-22 2020-02-26 Koninklijke Philips N.V. Coronary circulation using intra-cardiac echo
GB201820044D0 (en) * 2018-10-29 2019-01-23 Univ Oxford Innovation Ltd Radiomic signature of an epicardial region
JP7464997B2 (ja) 2018-09-21 2024-04-10 メンティス アー・ベー 心臓シミュレーション装置
EP3881758A4 (en) * 2018-11-13 2022-07-27 Suzhou Rainmed Medical Technology Co., Ltd. METHOD, DEVICE AND SYSTEM FOR DETECTING A VASCULAR EVALUATION PARAMETER BASED ON ANGIOGRAPHIC IMAGES
US10964017B2 (en) * 2018-11-15 2021-03-30 General Electric Company Deep learning for arterial analysis and assessment
JP7233209B2 (ja) * 2018-12-03 2023-03-06 朝日インテック株式会社 心臓シミュレータ
CN109700574B (zh) * 2018-12-21 2021-01-05 北京工业大学 一种基于ct影像数据制备钙化主动脉瓣的方法
CN109700475B (zh) * 2018-12-27 2021-01-08 浙江大学 一种冠脉搭桥参数的确定方法、装置、设备和存储介质
JP7241183B2 (ja) * 2019-01-11 2023-03-16 ヘモレンズ ダイアグノスティックス エスピー．ゼット オー．オー． 冠動脈における血行動態パラメータの患者固有モデリング
CN109872336B (zh) * 2019-03-13 2021-07-09 数坤(北京)网络科技股份有限公司 一种血管分割方法、设备及计算机存储介质
US10861157B2 (en) 2019-04-04 2020-12-08 Medtronic Vascular, Inc. System and methods for determining modified fractional flow reserve values
US11357573B2 (en) 2019-04-25 2022-06-14 International Business Machines Corporation Optimum treatment planning during coronary intervention by simultaneous simulation of a continuum of outcomes
JP6751178B2 (ja) * 2019-05-14 2020-09-02 キヤノンメディカルシステムズ株式会社 医用画像処理装置、医用画像処理方法および記録媒体
CN110368087B (zh) * 2019-06-06 2021-01-08 中国人民解放军北部战区总医院 一种信息处理方法和装置、及可读存储介质
CN110310744B (zh) * 2019-06-10 2021-12-24 暨南大学 窦房结虚拟生理组织的构建方法、存储介质和计算设备
KR102130254B1 (ko) * 2019-10-15 2020-07-03 주식회사 실리콘사피엔스 대상자 고유의 혈관에 대한 혈류 시뮬레이션 방법 및 장치
US11026749B1 (en) * 2019-12-05 2021-06-08 Board Of Regents Of The University Of Nebraska Computational simulation platform for planning of interventional procedures
CN111241759B (zh) * 2020-01-13 2024-03-26 北京工业大学 一种基于零维血流动力学模型的ffr快速计算方法
DE102020200750A1 (de) * 2020-01-22 2021-07-22 Siemens Healthcare Gmbh Bereitstellen eines Blutflussparametersatzes einer Gefäßmalformation
CN111317455B (zh) * 2020-03-03 2022-02-22 上海联影医疗科技股份有限公司 血流动力学参数确定方法、装置、设备及存储介质
CN111616678B (zh) * 2020-04-17 2023-04-14 清华大学 一种基于智能冠状动脉支架的再狭窄监测装置及方法
US11538153B2 (en) * 2020-08-31 2022-12-27 Huidan Yu Non-invasive functional assessment technique for determining hemodynamic severity of an arterial stenosis
CN112617791B (zh) * 2020-12-22 2022-09-20 杭州晟视科技有限公司 一种模拟血管搏动的方法、装置及存储介质
WO2022136688A1 (en) * 2020-12-23 2022-06-30 Flowreserve Labs S.L. Non-invasive method for determining a vessel damage indicator
CN112950537A (zh) * 2021-01-26 2021-06-11 上海友脉科技有限责任公司 一种冠脉血流储备分数获取系统、方法及介质
US20220378506A1 (en) * 2021-05-27 2022-12-01 Board Of Regents Of The University Of Nebraska Patient-specific computational simulation of coronary artery bypass grafting
CN113648059B (zh) * 2021-08-26 2023-09-29 上海联影医疗科技股份有限公司 手术规划评估方法、计算机设备和存储介质
CN113658701A (zh) * 2021-08-26 2021-11-16 上海联影医疗科技股份有限公司 术后评估方法、计算机设备和存储介质

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10026666A1 (de) 2000-05-29 2001-12-20 Gunther Burgard Verwendung von Hyaluronidase zur Prophylaxe und Behandlung von Herz-Kreislauf-Erkrankungen
US7912528B2 (en) * 2003-06-25 2011-03-22 Siemens Medical Solutions Usa, Inc. Systems and methods for automated diagnosis and decision support for heart related diseases and conditions
CN101355904B (zh) 2005-12-20 2012-01-11 皇家飞利浦电子股份有限公司 用于重建至少一部分目标的精密再现的重建单元
US7860290B2 (en) 2006-04-21 2010-12-28 Siemens Medical Solutions Usa, Inc. Three-dimensional (3D) modeling of coronary arteries
US7953266B2 (en) 2007-02-06 2011-05-31 Siemens Medical Solutions Usa, Inc. Robust vessel tree modeling
US8098918B2 (en) 2007-09-21 2012-01-17 Siemens Corporation Method and system for measuring left ventricle volume
US20110093243A1 (en) 2007-11-14 2011-04-21 Tawhai Merryn H Method for multi-scale meshing of branching biological structures
WO2009099340A1 (en) * 2008-02-04 2009-08-13 Iain Alexander Anderson Integrated-model musculoskeletal therapies
US9427173B2 (en) * 2008-05-09 2016-08-30 General Electric Company Determining mechanical force on aneurysms from a fluid dynamic model driven by vessel blood flow information
JP5089514B2 (ja) 2008-07-11 2012-12-05 キヤノン株式会社 撮像装置、及び撮像システム
US8200466B2 (en) 2008-07-21 2012-06-12 The Board Of Trustees Of The Leland Stanford Junior University Method for tuning patient-specific cardiovascular simulations
US8582854B2 (en) * 2008-09-15 2013-11-12 Siemens Aktiengesellschaft Method and system for automatic coronary artery detection
US9405996B2 (en) * 2008-09-18 2016-08-02 Siemens Aktiengesellschaft Method and system for generating a personalized anatomical heart model
US9405886B2 (en) 2009-03-17 2016-08-02 The Board Of Trustees Of The Leland Stanford Junior University Method for determining cardiovascular information
US9715637B2 (en) 2009-03-18 2017-07-25 Siemens Healthcare Gmbh Method and system for automatic aorta segmentation
US8224640B2 (en) 2009-09-08 2012-07-17 Siemens Aktiengesellschaft Method and system for computational modeling of the aorta and heart
CA2926666C (en) 2009-09-23 2018-11-06 Lightlab Imaging, Inc. Lumen morphology and vascular resistance measurements data collection systems, apparatus and methods
US8526699B2 (en) 2010-03-12 2013-09-03 Siemens Aktiengesellschaft Method and system for automatic detection and classification of coronary stenoses in cardiac CT volumes
US20110270051A1 (en) * 2010-05-03 2011-11-03 Morteza Naghavi Cardiovascular Disease Screening Method and Apparatus
US8682626B2 (en) 2010-07-21 2014-03-25 Siemens Aktiengesellschaft Method and system for comprehensive patient-specific modeling of the heart
US8315812B2 (en) * 2010-08-12 2012-11-20 Heartflow, Inc. Method and system for patient-specific modeling of blood flow
US8157742B2 (en) 2010-08-12 2012-04-17 Heartflow, Inc. Method and system for patient-specific modeling of blood flow
DE102010039312B4 (de) 2010-08-13 2020-02-13 Siemens Healthcare Gmbh Verfahren zur Simulation eines Blutflusses
US9119540B2 (en) 2010-09-16 2015-09-01 Siemens Aktiengesellschaft Method and system for non-invasive assessment of coronary artery disease
DE102010043849B3 (de) 2010-11-12 2012-02-16 Siemens Aktiengesellschaft Vorrichtung und Computertomograph zur Bestimmung und Darstellung der Durchblutung des Herzmuskels
US9141763B2 (en) 2011-02-07 2015-09-22 Siemens Aktiengesellschaft Method and system for patient-specific computational modeling and simulation for coupled hemodynamic analysis of cerebral vessels

Also Published As

Publication number Publication date
CN110085321A (zh) 2019-08-02
WO2013071219A1 (en) 2013-05-16
JP2014534889A (ja) 2014-12-25
KR20140091741A (ko) 2014-07-22
CN110085321B (zh) 2023-10-27
EP2776960B1 (en) 2021-09-01
JP5980942B2 (ja) 2016-08-31
US20130132054A1 (en) 2013-05-23
CN104081401A (zh) 2014-10-01
US10162932B2 (en) 2018-12-25
EP2776960A1 (en) 2014-09-17
IN2014CN03423A (pt) 2015-07-03

Similar Documents

Publication Publication Date Title
BR112014011342A2 (pt) método e sistema de modelagem anatômica e funcional multiescala de circulação coronária
Lee et al. Identification of high-risk plaques destined to cause acute coronary syndrome using coronary computed tomographic angiography and computational fluid dynamics
Kung et al. Predictive modeling of the virtual Hemi-Fontan operation for second stage single ventricle palliation: two patient-specific cases
Lorenzen et al. Inter-observer variation in delineation of the heart and left anterior descending coronary artery in radiotherapy for breast cancer: a multi-centre study from Denmark and the UK
EP2963574A3 (en) Method and system for prediction of post-stenting hemodynamic metrics for treatment planning of arterial stenosis
Jones et al. Sources of group differences in functional connectivity: an investigation applied to autism spectrum disorder
Spaan et al. Coronary structure and perfusion in health and disease
EP2966615A3 (en) Method and system for improved hemodynamic computation in coronary arteries
JP2014534889A5 (pt)
Sakellarios et al. Patient-specific computational modeling of subendothelial LDL accumulation in a stenosed right coronary artery: effect of hemodynamic and biological factors
Napp et al. Heart against veno-arterial ECMO: competition visualized
Kretschmer et al. Dynamically generated models for medical decision support systems
Brown et al. Importance of realistic LVAD profiles for assisted aortic simulations: evaluation of optimal outflow anastomosis locations
Restrepo et al. Surgical planning of the total cavopulmonary connection: robustness analysis
Gamilov et al. Computational simulations of fractional flow reserve variability
Sarifuddin et al. Effect of diffusivity on the transport of drug eluted from drug-eluting stent
Restrepo et al. Hemodynamic impact of superior vena cava placement in the Y-graft Fontan connection
Assmann et al. Dispersive aortic cannulas reduce aortic wall shear stress affecting atherosclerotic plaque embolization
Tang et al. Cardiovascular diseases and vulnerable plaques: data, modeling, predictions and clinical applications
Carrizo et al. Functional assessment of coronary artery disease by intravascular ultrasound and computational fluid dynamics simulation
Melchionna et al. Risk assessment of atherosclerotic plaques based on global biomechanics
Romagnoli et al. Comparison between mixed and central venous oxygen saturation in patients with severe acute heart failure after cardiac surgery: a prospective observational study
Zuin et al. Mathematics and transcatheter aortic valve implantation: Use of computational fluid dynamics and finite element analysis. Is this the future?
Vuity et al. The Glasgow Anterior Stabilisation (GAS) appliance: A novel orthodontic appliance for pre-maxillary stabilisation in bilateral cleft lip and palate
Menshykau et al. Mechanistic image-based modelling: concepts and applications

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]