JP5858931B2 - ナノ細孔内の分子を操作するためのシステムおよび方法 - Google Patents
ナノ細孔内の分子を操作するためのシステムおよび方法 Download PDFInfo
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- JP5858931B2 JP5858931B2 JP2012551978A JP2012551978A JP5858931B2 JP 5858931 B2 JP5858931 B2 JP 5858931B2 JP 2012551978 A JP2012551978 A JP 2012551978A JP 2012551978 A JP2012551978 A JP 2012551978A JP 5858931 B2 JP5858931 B2 JP 5858931B2
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- molecule
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- nanopore
- lipid bilayer
- electrical stimulus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
- G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Nanotechnology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/658,604 US8324914B2 (en) | 2010-02-08 | 2010-02-08 | Systems and methods for characterizing a molecule |
| US12/658,602 | 2010-02-08 | ||
| US12/658,591 | 2010-02-08 | ||
| US12/658,601 US20110192723A1 (en) | 2010-02-08 | 2010-02-08 | Systems and methods for manipulating a molecule in a nanopore |
| US12/658,602 US20120052188A1 (en) | 2010-02-08 | 2010-02-08 | Systems and methods for assembling a lipid bilayer on a substantially planar solid surface |
| US12/658,603 | 2010-02-08 | ||
| US12/658,591 US9605307B2 (en) | 2010-02-08 | 2010-02-08 | Systems and methods for forming a nanopore in a lipid bilayer |
| US12/658,603 US20110287414A1 (en) | 2010-02-08 | 2010-02-08 | Systems and methods for identifying a portion of a molecule |
| US12/658,601 | 2010-02-08 | ||
| US12/658,604 | 2010-02-08 | ||
| PCT/US2011/000205 WO2011097028A1 (en) | 2010-02-08 | 2011-02-04 | Systems and methods for manipulating a molecule in a nanopore |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015244065A Division JP6124982B2 (ja) | 2010-02-08 | 2015-12-15 | ナノ細孔を形成するためのシステムおよぴ方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013519088A JP2013519088A (ja) | 2013-05-23 |
| JP2013519088A5 JP2013519088A5 (cg-RX-API-DMAC7.html) | 2013-09-26 |
| JP5858931B2 true JP5858931B2 (ja) | 2016-02-10 |
Family
ID=44355716
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012551978A Active JP5858931B2 (ja) | 2010-02-08 | 2011-02-04 | ナノ細孔内の分子を操作するためのシステムおよび方法 |
| JP2015244065A Active JP6124982B2 (ja) | 2010-02-08 | 2015-12-15 | ナノ細孔を形成するためのシステムおよぴ方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015244065A Active JP6124982B2 (ja) | 2010-02-08 | 2015-12-15 | ナノ細孔を形成するためのシステムおよぴ方法 |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP2843405B8 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5858931B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN105273991B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011213234B2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2788331C (cg-RX-API-DMAC7.html) |
| GB (2) | GB2490847B8 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011097028A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (74)
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| WO2007146158A1 (en) | 2006-06-07 | 2007-12-21 | The Trustees Of Columbia University In The City Of New York | Dna sequencing by nanopore using modified nucleotides |
| US9605307B2 (en) | 2010-02-08 | 2017-03-28 | Genia Technologies, Inc. | Systems and methods for forming a nanopore in a lipid bilayer |
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| US8324914B2 (en) | 2010-02-08 | 2012-12-04 | Genia Technologies, Inc. | Systems and methods for characterizing a molecule |
| CN103282518B (zh) | 2010-12-17 | 2016-11-16 | 纽约哥伦比亚大学理事会 | 使用经修饰的核苷酸和纳米孔检测的dna边合成边测序 |
| WO2012088341A2 (en) | 2010-12-22 | 2012-06-28 | Genia Technologies, Inc. | Nanopore-based single dna molecule characterization, identification and isolation using speed bumps |
| US8962242B2 (en) | 2011-01-24 | 2015-02-24 | Genia Technologies, Inc. | System for detecting electrical properties of a molecular complex |
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| WO2013067208A1 (en) | 2011-11-02 | 2013-05-10 | Genia Technologies, Inc. | Systems and methods for determining genetic data |
| JP6178805B2 (ja) | 2012-02-16 | 2017-08-09 | ジニア テクノロジーズ, インコーポレイテッド | ナノ細孔センサーとともに使用するための二重層を作製するための方法 |
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| EP2836604B1 (en) | 2012-04-09 | 2021-09-15 | The Trustees of Columbia University in the City of New York | Method of preparation of nanopore and uses thereof |
| WO2013188841A1 (en) | 2012-06-15 | 2013-12-19 | Genia Technologies, Inc. | Chip set-up and high-accuracy nucleic acid sequencing |
| WO2013191793A1 (en) | 2012-06-20 | 2013-12-27 | The Trustees Of Columbia University In The City Of New York | Nucleic acid sequencing by nanopore detection of tag molecules |
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| US20150346188A1 (en) * | 2012-12-21 | 2015-12-03 | Ibis Biosciences, Inc. | Stabilized nanopore and micropore structures and methods for making and using the same |
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| WO2014144898A1 (en) | 2013-03-15 | 2014-09-18 | The Trustees Of Columbia University In The City Of New York | Method for detecting multiple predetermined compounds in a sample |
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| BR112012013074B1 (pt) * | 2009-12-01 | 2018-09-18 | Oxford Nanopore Technologies Limited | instrumento de análise e módulo para realizar análise bioquímica, e, método para operar um instrumento de análise para realizar análise bioquímica |
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2011
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| CA2788331A1 (en) | 2011-08-11 |
| EP2843405A2 (en) | 2015-03-04 |
| AU2011213234A2 (en) | 2013-01-10 |
| AU2011213234B2 (en) | 2015-05-14 |
| EP2843405B1 (en) | 2023-08-23 |
| EP2534284A4 (en) | 2017-01-25 |
| GB2496019B (en) | 2014-11-12 |
| CN105273991B (zh) | 2019-05-10 |
| EP2534284A1 (en) | 2012-12-19 |
| CN103298984A (zh) | 2013-09-11 |
| GB2490847A8 (en) | 2014-10-22 |
| AU2011213234A1 (en) | 2012-08-23 |
| CA2788331C (en) | 2018-04-03 |
| EP2534284B1 (en) | 2021-03-17 |
| GB2490847A (en) | 2012-11-14 |
| GB201216656D0 (en) | 2012-10-31 |
| CN103298984B (zh) | 2015-11-25 |
| JP2013519088A (ja) | 2013-05-23 |
| JP6124982B2 (ja) | 2017-05-10 |
| JP2016095314A (ja) | 2016-05-26 |
| CA2995178C (en) | 2023-09-12 |
| WO2011097028A1 (en) | 2011-08-11 |
| GB2490847B8 (en) | 2014-10-22 |
| GB2490847B (en) | 2014-04-23 |
| GB201216026D0 (en) | 2012-10-24 |
| CA2995178A1 (en) | 2011-08-11 |
| EP2843405B8 (en) | 2023-10-04 |
| GB2496019A (en) | 2013-05-01 |
| EP2843405A3 (en) | 2015-04-29 |
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