AU2001241474A1 - Biosensor compositions and methods of use - Google Patents

Biosensor compositions and methods of use

Info

Publication number
AU2001241474A1
AU2001241474A1 AU2001241474A AU4147401A AU2001241474A1 AU 2001241474 A1 AU2001241474 A1 AU 2001241474A1 AU 2001241474 A AU2001241474 A AU 2001241474A AU 4147401 A AU4147401 A AU 4147401A AU 2001241474 A1 AU2001241474 A1 AU 2001241474A1
Authority
AU
Australia
Prior art keywords
methods
biosensor
compositions
biosensor compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001241474A
Inventor
Hagan P. Bayley
Stefan G. Howorka
Liviu Movileanu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Texas A&M University System
Original Assignee
Texas A&M University System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Texas A&M University System filed Critical Texas A&M University System
Publication of AU2001241474A1 publication Critical patent/AU2001241474A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • C12Q1/6874Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria
AU2001241474A 2000-02-11 2001-02-12 Biosensor compositions and methods of use Abandoned AU2001241474A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18209700P 2000-02-11 2000-02-11
US60182097 2000-02-11
PCT/US2001/004482 WO2001059453A2 (en) 2000-02-11 2001-02-12 Biosensor compositions and methods of use

Publications (1)

Publication Number Publication Date
AU2001241474A1 true AU2001241474A1 (en) 2001-08-20

Family

ID=22667045

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001241474A Abandoned AU2001241474A1 (en) 2000-02-11 2001-02-12 Biosensor compositions and methods of use

Country Status (4)

Country Link
US (2) US6916665B2 (en)
EP (3) EP2083015B1 (en)
AU (1) AU2001241474A1 (en)
WO (1) WO2001059453A2 (en)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8206568B2 (en) * 1999-06-22 2012-06-26 President And Fellows Of Harvard College Material deposition techniques for control of solid state aperture surface properties
AU2002365115A1 (en) * 2001-07-20 2003-09-02 North Carolina State University Light addressable electrochemical detection of duplex structures
AU2003245272A1 (en) * 2002-05-10 2003-11-11 The Texas A And M University System Stochastic sensing through covalent interactions
US20090246879A1 (en) * 2002-12-20 2009-10-01 Callida Genomics Materials and Methods Relating to Nano-Tags and Nano-Brands
US20040180369A1 (en) * 2003-01-16 2004-09-16 North Carolina State University Photothermal detection of nucleic acid hybridization
US20100000881A1 (en) * 2003-10-30 2010-01-07 North Carolina State University Electrochemical detection of nucleic acid hybridization
US20050191651A1 (en) * 2003-10-30 2005-09-01 North Carolina State University Temperature-jump enhanced electrochemical detection of nucleic acid hybridization
EP1548444A1 (en) * 2003-12-23 2005-06-29 Paul Scherrer Institut An assay chip, and uses of said assay chip to determine molecular structures and functions
US7949472B1 (en) 2004-06-24 2011-05-24 The United States Of America As Represented By The National Aeronautics And Space Administration Rapid polymer sequencer
US20060057585A1 (en) * 2004-09-10 2006-03-16 Mcallister William H Nanostepper/sensor systems and methods of use thereof
EP1805680B1 (en) * 2004-10-06 2015-03-25 Board of Supervisors of Louisiana Channel current cheminformatics and bioengineering methods for immunological screening, single-molecule analysis, and single-molecular-interaction analysis
ATE529734T1 (en) * 2005-04-06 2011-11-15 Harvard College MOLECULAR CHARACTERIZATION WITH CARBON NANOTUBE CONTROL
KR100691806B1 (en) * 2005-08-04 2007-03-12 삼성전자주식회사 Method for short nucleic acids detection using bead and nanopore, and Detection Apparatus thereby
GB0523282D0 (en) 2005-11-15 2005-12-21 Isis Innovation Methods using pores
CN101495656B (en) * 2006-06-07 2017-02-08 纽约哥伦比亚大学理事会 DNA sequencing by nanopore using modified nucleotides
EP3798317B1 (en) * 2007-04-04 2024-01-03 The Regents of the University of California Compositions, devices, systems, and methods for using a nanopore
EP2158476B8 (en) 2007-05-08 2019-10-09 Trustees of Boston University Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
WO2008157640A2 (en) 2007-06-18 2008-12-24 Illumina, Inc. Microfabrication methods for the optimal patterning of substrates
US7906316B2 (en) * 2007-07-05 2011-03-15 The Johns Hopkins University Apparatus for detecting molecules
GB2453377A (en) 2007-10-05 2009-04-08 Isis Innovation Transmembrane protein pores and molecular adapters therefore.
US8628940B2 (en) 2008-09-24 2014-01-14 Pacific Biosciences Of California, Inc. Intermittent detection during analytical reactions
CA2991818C (en) 2008-03-28 2022-10-11 Pacific Biosciences Of California, Inc. Compositions and methods for nucleic acid sequencing
CN102144037A (en) * 2008-07-07 2011-08-03 牛津纳米孔技术有限公司 Base-detecting pore
EP2682460B1 (en) 2008-07-07 2017-04-26 Oxford Nanopore Technologies Limited Enzyme-pore constructs
US20100099198A1 (en) * 2008-07-11 2010-04-22 Board Of Regents, The University Of Texas System Apparatus and system for pattern recognition sensing for biomolecules
US8945912B2 (en) 2008-09-29 2015-02-03 The Board Of Trustees Of The University Of Illinois DNA sequencing and amplification systems using nanoscale field effect sensor arrays
GB0820927D0 (en) 2008-11-14 2008-12-24 Isis Innovation Method
JP5843614B2 (en) 2009-01-30 2016-01-13 オックスフォード ナノポア テクノロジーズ リミテッド Adapters for nucleic acid constructs in transmembrane sequencing
GB0905140D0 (en) 2009-03-25 2009-05-06 Isis Innovation Method
US9376713B2 (en) * 2009-09-23 2016-06-28 The Board Of Trustees Of The University Of Illinois Label free detection of nucleic acid amplification
AU2010301128B2 (en) 2009-09-30 2014-09-18 Quantapore, Inc. Ultrafast sequencing of biological polymers using a labeled nanopore
US8324914B2 (en) * 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
GB2490847B8 (en) * 2010-02-08 2014-09-24 Genia Technologies Inc Systems and methods for manipulating a molecule in a nanopore
US20110192723A1 (en) * 2010-02-08 2011-08-11 Genia Technologies, Inc. Systems and methods for manipulating a molecule in a nanopore
US9605307B2 (en) 2010-02-08 2017-03-28 Genia Technologies, Inc. Systems and methods for forming a nanopore in a lipid bilayer
US9678055B2 (en) 2010-02-08 2017-06-13 Genia Technologies, Inc. Methods for forming a nanopore in a lipid bilayer
US8810236B2 (en) 2010-03-09 2014-08-19 Nokia Corporation Apparatus and associated methods
US10010272B2 (en) 2010-05-27 2018-07-03 Profusa, Inc. Tissue-integrating electronic apparatus
US9395353B2 (en) 2010-07-14 2016-07-19 The Curators Of The University Of Missouri Nanopore-facilitated single molecule detection of nucleic acid
US9593370B2 (en) 2010-10-01 2017-03-14 Oxford Nanopore Technologies Ltd. Biochemical analysis apparatus and rotary valve
KR101690535B1 (en) * 2010-10-06 2017-01-09 프로퓨사 인코퍼레이티드 Tissue-integrating sensors
ES2641871T3 (en) 2010-12-17 2017-11-14 The Trustees Of Columbia University In The City Of New York DNA sequencing by synthesis using modified nucleotides and nanopore detection
WO2012088341A2 (en) 2010-12-22 2012-06-28 Genia Technologies, Inc. Nanopore-based single dna molecule characterization, identification and isolation using speed bumps
US9581563B2 (en) 2011-01-24 2017-02-28 Genia Technologies, Inc. System for communicating information from an array of sensors
US9110478B2 (en) 2011-01-27 2015-08-18 Genia Technologies, Inc. Temperature regulation of measurement arrays
CN103460040B (en) 2011-02-11 2016-08-17 牛津纳米孔技术有限公司 Saltant type hole
EP2724148A4 (en) 2011-06-24 2014-12-03 Electronic Biosciences Inc High contrast signal to noise ratio device components
CN103827320B (en) 2011-07-25 2017-04-26 牛津纳米孔技术有限公司 Hairpin loop method for double strand polynucleotide sequencing using transmembrane pores
BRMU9102088U2 (en) * 2011-08-25 2016-04-26 Univ Fed Pernambuco use of a protein nanopore for detection, identification, quantification and real time monitoring of microcystins in aqueous systems
JP6333179B2 (en) * 2012-01-20 2018-05-30 ジニア テクノロジーズ, インコーポレイテッド Nanopore-based molecular detection and sequencing
US8986629B2 (en) 2012-02-27 2015-03-24 Genia Technologies, Inc. Sensor circuit for controlling, detecting, and measuring a molecular complex
WO2013154999A2 (en) 2012-04-09 2013-10-17 The Trustees Of Columbia University In The City Of New York Method of preparation of nanopore and uses thereof
US9777049B2 (en) 2012-04-10 2017-10-03 Oxford Nanopore Technologies Ltd. Mutant lysenin pores
US9494554B2 (en) 2012-06-15 2016-11-15 Genia Technologies, Inc. Chip set-up and high-accuracy nucleic acid sequencing
WO2014013259A1 (en) 2012-07-19 2014-01-23 Oxford Nanopore Technologies Limited Ssb method
US9651539B2 (en) 2012-10-28 2017-05-16 Quantapore, Inc. Reducing background fluorescence in MEMS materials by low energy ion beam treatment
US9605309B2 (en) 2012-11-09 2017-03-28 Genia Technologies, Inc. Nucleic acid sequencing using tags
WO2014100481A2 (en) * 2012-12-20 2014-06-26 Electornic Biosciences Inc. Modified alpha hemolysin polypeptides and methods of use
US9759711B2 (en) 2013-02-05 2017-09-12 Genia Technologies, Inc. Nanopore arrays
GB201314695D0 (en) 2013-08-16 2013-10-02 Oxford Nanopore Tech Ltd Method
CN105209634B (en) 2013-03-08 2020-05-12 牛津纳米孔技术公司 Enzyme arrest method
JP6457998B2 (en) 2013-03-14 2019-01-23 プロフサ,インコーポレイテッド Method and device for correcting optical signals
US10732183B2 (en) 2013-03-15 2020-08-04 The Trustees Of Columbia University In The City Of New York Method for detecting multiple predetermined compounds in a sample
US9732379B2 (en) 2013-03-15 2017-08-15 The Curators Of The University Of Missouri Encoded nanopore sensor for multiplex nucleic acids detection
GB201313477D0 (en) 2013-07-29 2013-09-11 Univ Leuven Kath Nanopore biosensors for detection of proteins and nucleic acids
DK3351645T3 (en) 2013-05-24 2020-09-21 Illumina Cambridge Ltd Pyrophosphorolytic sequencing using nanopores
US9862997B2 (en) 2013-05-24 2018-01-09 Quantapore, Inc. Nanopore-based nucleic acid analysis with mixed FRET detection
JP2016523608A (en) 2013-06-06 2016-08-12 プロフサ,インコーポレイテッド Apparatus and method for detecting optical signal from embedded sensor
US9551697B2 (en) 2013-10-17 2017-01-24 Genia Technologies, Inc. Non-faradaic, capacitively coupled measurement in a nanopore cell array
CA2926138A1 (en) 2013-10-23 2015-04-30 Genia Technologies, Inc. High speed molecular sensing with nanopores
US9567630B2 (en) 2013-10-23 2017-02-14 Genia Technologies, Inc. Methods for forming lipid bilayers on biochips
AU2015208919B9 (en) 2014-01-22 2021-04-01 Oxford Nanopore Technologies Limited Method for attaching one or more polynucleotide binding proteins to a target polynucleotide
GB201403096D0 (en) 2014-02-21 2014-04-09 Oxford Nanopore Tech Ltd Sample preparation method
EP3122759B1 (en) 2014-03-24 2022-06-01 The Trustees of Columbia University in the City of New York Chemical methods for producing tagged nucleotides
EP3137627A1 (en) 2014-05-02 2017-03-08 Oxford Nanopore Technologies Limited Method of improving the movement of a target polynucleotide with respect to a transmembrane pore
WO2016028887A1 (en) 2014-08-19 2016-02-25 Pacific Biosciences Of California, Inc. Compositions and methods for enrichment of nucleic acids
KR20170042794A (en) 2014-09-01 2017-04-19 브이아이비 브이지더블유 Mutant csgg pores
WO2016055778A1 (en) 2014-10-07 2016-04-14 Oxford Nanopore Technologies Limited Mutant pores
JP6740222B2 (en) 2014-10-10 2020-08-12 クアンタポール, インコーポレイテッド Nanopore-based polymer analysis with fluorescent labels quenching each other
GB201418159D0 (en) 2014-10-14 2014-11-26 Oxford Nanopore Tech Ltd Method
CN107002126B (en) 2014-10-24 2021-05-25 昆塔波尔公司 Efficient optical analysis of polymers using nanostructure arrays
GB201502810D0 (en) 2015-02-19 2015-04-08 Oxford Nanopore Tech Ltd Method
GB201502809D0 (en) 2015-02-19 2015-04-08 Oxford Nanopore Tech Ltd Mutant pore
US11169138B2 (en) 2015-04-14 2021-11-09 Katholieke Universiteit Leuven Nanopores with internal protein adaptors
US20190078145A1 (en) 2015-12-08 2019-03-14 Quantapore, Inc. Method of translocating nucleic acids through nanopores
JP7237586B2 (en) 2015-12-08 2023-03-13 カトリック ユニヴェルシテット ルーヴェン カーユー ルーヴェン リサーチ アンド ディベロップメント Modified Nanopores, Compositions Containing Them and Uses Thereof
US11066702B2 (en) 2016-01-15 2021-07-20 Quantapore, Inc. Optically-based nanopore analysis with reduced background
CN108884150A (en) 2016-03-02 2018-11-23 牛津纳米孔技术公司 It is mutated hole
EP3936863A1 (en) 2016-03-21 2022-01-12 Nooma Bio, Inc. Wafer-scale assembly of insulator-membrane-insulator devices for nanopore sensing
US11486873B2 (en) 2016-03-31 2022-11-01 Ontera Inc. Multipore determination of fractional abundance of polynucleotide sequences in a sample
JP7364333B2 (en) 2016-04-06 2023-10-18 オックスフォード ナノポール テクノロジーズ ピーエルシー mutant pore
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
JP2019517252A (en) 2016-05-31 2019-06-24 クアンタポール, インコーポレイテッド Two-color nanopore sequencing
US10823721B2 (en) 2016-07-05 2020-11-03 Quantapore, Inc. Optically based nanopore sequencing
EP3500684A4 (en) 2016-08-19 2020-02-26 Quantapore Inc. Optically-based nanopore sequencing using quenching agents
GB201620450D0 (en) * 2016-12-01 2017-01-18 Oxford Nanopore Tech Ltd Method
WO2018119400A1 (en) 2016-12-22 2018-06-28 Profusa, Inc. System and single-channel luminescent sensor for and method of determining analyte value
GB201707140D0 (en) 2017-05-04 2017-06-21 Oxford Nanopore Tech Ltd Method
WO2019002893A1 (en) 2017-06-30 2019-01-03 Vib Vzw Novel protein pores
CN107505272B (en) * 2017-08-10 2020-09-25 东软威特曼生物科技(南京)有限公司 Low-density lipoprotein cholesterol detection kit and use method thereof
JP2021513962A (en) * 2018-02-15 2021-06-03 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft Nanopore protein conjugates for detection and analysis of analytes
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method
GB201809323D0 (en) 2018-06-06 2018-07-25 Oxford Nanopore Tech Ltd Method
GB201814676D0 (en) * 2018-09-10 2018-10-24 Secr Defence Improved forensic methods and products for extracting and amplifying trace DNA for DNA sequencing
RS20201166A1 (en) * 2020-09-28 2022-03-31 Univerzitet U Beogradu Detection of toxins using nanopore

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US94526A (en) * 1869-09-07 Improved mail-bag
US5525464A (en) 1987-04-01 1996-06-11 Hyseq, Inc. Method of sequencing by hybridization of oligonucleotide probes
US5202231A (en) 1987-04-01 1993-04-13 Drmanac Radoje T Method of sequencing of genomes by hybridization of oligonucleotide probes
DE68926118T2 (en) * 1988-08-18 1996-08-22 Au Membrane & Biotech Res Inst IMPROVEMENTS IN SENSITIVITY AND SELECTIVITY OF ION CHANNEL MEMBRANE BIO SENSORS
EP0455705B1 (en) * 1989-01-27 1997-05-28 Australian Membrane And Biotechnology Research Institute Receptor membranes and ionophore gating
US5368712A (en) * 1989-11-02 1994-11-29 Synporin Technologies, Inc. Biologically mimetic synthetic ion channel transducers
US5373797A (en) 1992-10-19 1994-12-20 Bottoms Associates, Inc. Hem former
JPH09500102A (en) 1993-04-28 1997-01-07 ウォーセスター ファウンデーション フォー エクスペリメンタル バイオロジー Cell-directed dissolution pore forming agent
US5777078A (en) 1993-04-28 1998-07-07 Worcester Foundation For Experimental Biology Triggered pore-forming agents
EP0723598B1 (en) 1993-09-27 2004-01-14 Arch Development Corporation Methods and compositions for efficient nucleic acid sequencing
US5795782A (en) * 1995-03-17 1998-08-18 President & Fellows Of Harvard College Characterization of individual polymer molecules based on monomer-interface interactions
WO1997020203A1 (en) * 1995-11-28 1997-06-05 Thomas Schalkhammer Novel membranes and membrane dna/rna sensors
US20020042048A1 (en) 1997-01-16 2002-04-11 Radoje Drmanac Methods and compositions for detection or quantification of nucleic acid species
AU8586298A (en) * 1997-07-25 1999-02-16 University Of Massachusetts Designed protein pores as components for biosensors
CA2300940A1 (en) 1997-08-15 1999-02-25 Hyseq, Inc. Methods and compositions for detection or quantification of nucleic acid species
US6426231B1 (en) * 1998-11-18 2002-07-30 The Texas A&M University System Analyte sensing mediated by adapter/carrier molecules

Also Published As

Publication number Publication date
EP2261240A3 (en) 2011-09-28
EP2083015A2 (en) 2009-07-29
EP2083015B1 (en) 2016-04-06
EP1255772A2 (en) 2002-11-13
WO2001059453A2 (en) 2001-08-16
EP2261240B1 (en) 2015-09-02
EP2083015A3 (en) 2009-11-11
WO2001059453A3 (en) 2002-04-25
EP2261240A2 (en) 2010-12-15
US6916665B2 (en) 2005-07-12
US20020094526A1 (en) 2002-07-18
US20050208574A1 (en) 2005-09-22

Similar Documents

Publication Publication Date Title
AU2001241474A1 (en) Biosensor compositions and methods of use
AU2002320058A1 (en) Magnetic-nanoparticle conjugates and methods of use
AU2001285020A1 (en) P97-active agent conjugates and their methods of use
AU2002230831A1 (en) Compositions of human proteins and method of use thereof
AU4520801A (en) Novel substituted phenanthridinones and methods of use thereof
AU2003259735A1 (en) Small-mer compositions and methods of use
AU2002225954A1 (en) Dipeptidylpeptidases and methods of use
AU2002314466A1 (en) Withasol and methods of use
AU2001234437A1 (en) Deicing compositions and methods of use
AU2001281140A1 (en) Anti-plasmodium compositions and methods of use
AU2003299441A1 (en) Nf-hev compositions and methods of use
AU2002350079A1 (en) Gel composition and methods of use
AU2002256543A1 (en) Compositions containing heteropolymers and methods of using same
AU2002213346A1 (en) Osteopontin-coated surfaces and methods of use
AU2001280721A1 (en) Compositions of iodonium compounds and methods and uses thereof
AU2001293048A1 (en) Antiviral compositions and methods of use
AU2001255696A1 (en) Telomerase inhibitors and methods of their use
AU2002363938A1 (en) Methods and use of motoneuronotropic factors
AU2962400A (en) Cleaner composition and method of use thereof
AU2001264863A1 (en) Preparation of fagopyritols and uses therefor
AU5179800A (en) Mycolactone and related compounds, compositions and methods of use
AU2001261496A1 (en) Luxo-sigma54 interactions and methods of use
AU2001268236A1 (en) Use of aicar and related compounds
AU2001249692A1 (en) Phospholipid scramblases and methods of use thereof
AU4839100A (en) Methods of using and compositions comprising n-desmethylzolpidem