JP5832302B2 - ケラチンへの局所薬剤デリバリーにおける表面活性タンパク質の組成物、使用及び使用方法 - Google Patents

ケラチンへの局所薬剤デリバリーにおける表面活性タンパク質の組成物、使用及び使用方法 Download PDF

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Publication number
JP5832302B2
JP5832302B2 JP2011551471A JP2011551471A JP5832302B2 JP 5832302 B2 JP5832302 B2 JP 5832302B2 JP 2011551471 A JP2011551471 A JP 2011551471A JP 2011551471 A JP2011551471 A JP 2011551471A JP 5832302 B2 JP5832302 B2 JP 5832302B2
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Prior art keywords
surface active
active protein
nail
protein
hydrophobin
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JP2011551471A
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Japanese (ja)
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JP2012518669A (ja
JP2012518669A5 (enExample
Inventor
ブーテ アンドレアス
ブーテ アンドレアス
ハーフナー アンドレアス
ハーフナー アンドレアス
カウフマン フランツ
カウフマン フランツ
フィードラー バベッテ
フィードラー バベッテ
モイラー ギド
モイラー ギド
ブラッドリー ゴードン
ブラッドリー ゴードン
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BRAIN Biotech AG
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BRAIN Biotechnology Research and Information Network AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2011551471A 2009-02-26 2010-02-19 ケラチンへの局所薬剤デリバリーにおける表面活性タンパク質の組成物、使用及び使用方法 Expired - Fee Related JP5832302B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09153770 2009-02-26
EP09153770.4 2009-02-26
PCT/EP2010/052125 WO2010097344A1 (en) 2009-02-26 2010-02-19 Compositions, use and method for the use of surface active proteins in topical drug delivery across keratin

Publications (3)

Publication Number Publication Date
JP2012518669A JP2012518669A (ja) 2012-08-16
JP2012518669A5 JP2012518669A5 (enExample) 2014-07-31
JP5832302B2 true JP5832302B2 (ja) 2015-12-16

Family

ID=40834317

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011551471A Expired - Fee Related JP5832302B2 (ja) 2009-02-26 2010-02-19 ケラチンへの局所薬剤デリバリーにおける表面活性タンパク質の組成物、使用及び使用方法

Country Status (8)

Country Link
US (1) US8758730B2 (enExample)
EP (1) EP2400988B1 (enExample)
JP (1) JP5832302B2 (enExample)
KR (1) KR20110130440A (enExample)
CN (1) CN102333546B (enExample)
CA (1) CA2784516C (enExample)
WO (1) WO2010097344A1 (enExample)
ZA (1) ZA201203028B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013113451A2 (en) * 2012-01-31 2013-08-08 Unilever Plc Personal care composition
AU2013302822B2 (en) 2012-08-16 2016-06-02 Sun Pharmaceutical Industries, Inc. Method of treating onychomycosis
CN103980353A (zh) * 2014-05-21 2014-08-13 乔明强 一种疏水蛋白及其组成的药物制剂
MX2018005199A (es) * 2015-10-26 2018-07-06 Basf Se Productos para el cuidado bucal y metodos que comprenden hlps.
CN112198315B (zh) * 2020-09-11 2023-10-27 杭州奥泰生物技术股份有限公司 一种采集及检测指甲或趾甲样本中滥用药物的方法
CN112791048B (zh) * 2020-12-31 2023-01-17 海南海神同洲制药有限公司 一种硝酸舍他康唑栓及其制备方法
CN115701464B (zh) * 2021-08-02 2024-06-11 江苏金太阳纺织科技股份有限公司 超疏水整理剂及其制备方法与应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3807915A1 (de) * 1988-03-10 1989-09-21 Wella Ag Mittel zur festigung der frisur und pflege des haares
FR2673537B1 (fr) 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
WO1996041882A1 (en) 1995-06-12 1996-12-27 Proefstation Voor De Champignoncultuur Hydrophobins from edible fungi, genes, nucleotide sequences and dna-fragments encoding for said hydrophobins, and expression thereof
WO1997009960A1 (en) 1995-09-14 1997-03-20 Sorenson Pharmaceutical, Inc. Composition and method for treating diseased nails
JP4227677B2 (ja) 1996-12-10 2009-02-18 杏林製薬株式会社 被膜形成性抗真菌剤組成物
US6517863B1 (en) * 1999-01-20 2003-02-11 Usbiomaterials Corporation Compositions and methods for treating nails and adjacent tissues
GB0019283D0 (en) 2000-08-04 2000-09-27 Novartis Ag Organic compounds
FR2833490B1 (fr) 2001-12-14 2004-12-10 Oreal Utilisition cosmetique d'au moins une hydrophobine pour le traitement des matieres keratiniques et compositions mises en oeuvre
US6899890B2 (en) * 2002-03-20 2005-05-31 Kv Pharmaceutical Company Bioadhesive drug delivery system
WO2004000880A1 (en) 2002-06-21 2003-12-31 Applied Nanosystems B.V. Method of binding a compound to a surface
EP1848733B1 (de) 2005-02-07 2017-06-21 Basf Se Neue hydrophobinfusionsproteine, deren herstellung und verwendung
US20090297884A1 (en) 2005-03-30 2009-12-03 Basf Aktiengesellschaft Use of hydrophobins for the surface treatment of hardened mineral building materials, natural stone, artificial stone and ceramics
WO2006103638A2 (en) 2005-03-31 2006-10-05 Ranbaxy Laboratories Limited Topical pharmaceutical compositions of terbinafine and processes for their preparation
US20100170142A1 (en) 2005-04-01 2010-07-08 Basf Aktiengesellschaft Use of Proteins as Demulsifying Agents
DE102005029704A1 (de) * 2005-06-24 2007-01-11 Basf Ag Verwendung von Hydrophobin-Polypeptiden sowie Konjugaten aus Hydrophobin-Polypeptiden mit Wirk-oder Effektstoffen und ihre Herstellung sowie deren Einsatz in der Kosmetik
DE102005033002A1 (de) 2005-07-14 2007-01-18 Basf Ag Wässrige Monomeremulsionen enthaltend Hydrophobin
FR2892023B1 (fr) * 2005-10-14 2009-09-25 Galderma Sa Composition pharmaceutique a base d'amorolfine et d'agent filmogene hydrosoluble pour application ungueale et peri-ungueale
KR20100022482A (ko) 2007-05-24 2010-03-02 바스프 에스이 고체의 결정화에서 보조제로서의 히드로포빈의 용도
CA2698293A1 (en) 2007-09-13 2009-03-26 Thomas Subkowski Use of hydrophobin polypeptides as penetration intensifiers
CN102089051A (zh) 2008-07-11 2011-06-08 巴斯夫欧洲公司 作为形态学改变剂的两亲性蛋白质

Also Published As

Publication number Publication date
WO2010097344A1 (en) 2010-09-02
CA2784516C (en) 2020-01-07
EP2400988B1 (en) 2016-04-13
EP2400988A1 (en) 2012-01-04
JP2012518669A (ja) 2012-08-16
CA2784516A1 (en) 2011-09-02
US8758730B2 (en) 2014-06-24
CN102333546B (zh) 2014-11-26
KR20110130440A (ko) 2011-12-05
CN102333546A (zh) 2012-01-25
ZA201203028B (en) 2013-01-30
US20120058199A1 (en) 2012-03-08

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