CN102333546B - 用于在跨角蛋白的局部药物递送中使用表面活性蛋白的组合物、用途和方法 - Google Patents

用于在跨角蛋白的局部药物递送中使用表面活性蛋白的组合物、用途和方法 Download PDF

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Publication number
CN102333546B
CN102333546B CN201080009474.2A CN201080009474A CN102333546B CN 102333546 B CN102333546 B CN 102333546B CN 201080009474 A CN201080009474 A CN 201080009474A CN 102333546 B CN102333546 B CN 102333546B
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China
Prior art keywords
hydrophobin
active ingredient
use according
nail
patient
Prior art date
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Expired - Fee Related
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CN201080009474.2A
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English (en)
Chinese (zh)
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CN102333546A (zh
Inventor
A·布斯
A·哈夫纳
F·考夫曼
B·费德勒
G·莫伊雷尔
G·布拉德雷
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BRAIN Biotech AG
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BASF SE
BRAIN Biotechnology Research and Information Network AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201080009474.2A 2009-02-26 2010-02-19 用于在跨角蛋白的局部药物递送中使用表面活性蛋白的组合物、用途和方法 Expired - Fee Related CN102333546B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09153770.4 2009-02-26
EP09153770 2009-02-26
PCT/EP2010/052125 WO2010097344A1 (en) 2009-02-26 2010-02-19 Compositions, use and method for the use of surface active proteins in topical drug delivery across keratin

Publications (2)

Publication Number Publication Date
CN102333546A CN102333546A (zh) 2012-01-25
CN102333546B true CN102333546B (zh) 2014-11-26

Family

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CN201080009474.2A Expired - Fee Related CN102333546B (zh) 2009-02-26 2010-02-19 用于在跨角蛋白的局部药物递送中使用表面活性蛋白的组合物、用途和方法

Country Status (8)

Country Link
US (1) US8758730B2 (enExample)
EP (1) EP2400988B1 (enExample)
JP (1) JP5832302B2 (enExample)
KR (1) KR20110130440A (enExample)
CN (1) CN102333546B (enExample)
CA (1) CA2784516C (enExample)
WO (1) WO2010097344A1 (enExample)
ZA (1) ZA201203028B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013113451A2 (en) * 2012-01-31 2013-08-08 Unilever Plc Personal care composition
WO2014028422A1 (en) * 2012-08-16 2014-02-20 Dusa Pharmaceuticals, Inc. Method of treating onychomycosis
CN103980353A (zh) * 2014-05-21 2014-08-13 乔明强 一种疏水蛋白及其组成的药物制剂
RU2759134C2 (ru) * 2015-10-26 2021-11-09 Басф Се Продукты и способы для ухода за полостью рта, содержащие hlp
CN112198315B (zh) * 2020-09-11 2023-10-27 杭州奥泰生物技术股份有限公司 一种采集及检测指甲或趾甲样本中滥用药物的方法
CN112791048B (zh) * 2020-12-31 2023-01-17 海南海神同洲制药有限公司 一种硝酸舍他康唑栓及其制备方法
CN115701464B (zh) * 2021-08-02 2024-06-11 江苏金太阳纺织科技股份有限公司 超疏水整理剂及其制备方法与应用

Citations (2)

* Cited by examiner, † Cited by third party
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US20030180366A1 (en) * 2002-03-20 2003-09-25 Kirschner Mitchell I. Bioadhesive drug delivery system
CN101203207A (zh) * 2005-06-24 2008-06-18 巴斯福股份公司 疏水蛋白-多肽和具有活性剂和效果剂的来自疏水蛋白-多肽的缀合物的应用及其制备及其在化妆品工业中的应用

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DE3807915A1 (de) * 1988-03-10 1989-09-21 Wella Ag Mittel zur festigung der frisur und pflege des haares
FR2673537B1 (fr) 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
WO1996041882A1 (en) 1995-06-12 1996-12-27 Proefstation Voor De Champignoncultuur Hydrophobins from edible fungi, genes, nucleotide sequences and dna-fragments encoding for said hydrophobins, and expression thereof
EP0866683A4 (en) 1995-09-14 1999-01-07 Sorenson Pharmaceutical Inc MEANS AND METHOD FOR TREATING DISEASE NAILS
JP4227677B2 (ja) * 1996-12-10 2009-02-18 杏林製薬株式会社 被膜形成性抗真菌剤組成物
US6517863B1 (en) * 1999-01-20 2003-02-11 Usbiomaterials Corporation Compositions and methods for treating nails and adjacent tissues
GB0019283D0 (en) 2000-08-04 2000-09-27 Novartis Ag Organic compounds
FR2833490B1 (fr) 2001-12-14 2004-12-10 Oreal Utilisition cosmetique d'au moins une hydrophobine pour le traitement des matieres keratiniques et compositions mises en oeuvre
WO2004000880A1 (en) 2002-06-21 2003-12-31 Applied Nanosystems B.V. Method of binding a compound to a surface
JP5250264B2 (ja) 2005-02-07 2013-07-31 ビーエーエスエフ ソシエタス・ヨーロピア 新規ハイドロフォビン融合タンパク質、その製造および使用
WO2006103230A1 (de) 2005-03-30 2006-10-05 Basf Aktiengesellschaft Verwendung von hydrophobinen zur oberflächenbehandlung von gehärteten mineralischen baustoffen, naturstein, kunststein und keramiken
WO2006103638A2 (en) 2005-03-31 2006-10-05 Ranbaxy Laboratories Limited Topical pharmaceutical compositions of terbinafine and processes for their preparation
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DE102005033002A1 (de) 2005-07-14 2007-01-18 Basf Ag Wässrige Monomeremulsionen enthaltend Hydrophobin
FR2892023B1 (fr) 2005-10-14 2009-09-25 Galderma Sa Composition pharmaceutique a base d'amorolfine et d'agent filmogene hydrosoluble pour application ungueale et peri-ungueale
CA2687490A1 (en) 2007-05-24 2008-11-27 Basf Se Use of hydrophobins as auxiliaries in the crystallization of solids
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Publication number Priority date Publication date Assignee Title
US20030180366A1 (en) * 2002-03-20 2003-09-25 Kirschner Mitchell I. Bioadhesive drug delivery system
CN101203207A (zh) * 2005-06-24 2008-06-18 巴斯福股份公司 疏水蛋白-多肽和具有活性剂和效果剂的来自疏水蛋白-多肽的缀合物的应用及其制备及其在化妆品工业中的应用

Non-Patent Citations (1)

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Also Published As

Publication number Publication date
CA2784516A1 (en) 2011-09-02
JP2012518669A (ja) 2012-08-16
CA2784516C (en) 2020-01-07
JP5832302B2 (ja) 2015-12-16
CN102333546A (zh) 2012-01-25
US8758730B2 (en) 2014-06-24
ZA201203028B (en) 2013-01-30
EP2400988A1 (en) 2012-01-04
EP2400988B1 (en) 2016-04-13
US20120058199A1 (en) 2012-03-08
WO2010097344A1 (en) 2010-09-02
KR20110130440A (ko) 2011-12-05

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