JP5534497B2 - トリアゾール類の合成方法 - Google Patents

トリアゾール類の合成方法 Download PDF

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Publication number
JP5534497B2
JP5534497B2 JP2008515957A JP2008515957A JP5534497B2 JP 5534497 B2 JP5534497 B2 JP 5534497B2 JP 2008515957 A JP2008515957 A JP 2008515957A JP 2008515957 A JP2008515957 A JP 2008515957A JP 5534497 B2 JP5534497 B2 JP 5534497B2
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JP
Japan
Prior art keywords
compound
alkyl
acid
unsaturated
formula
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Expired - Fee Related
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JP2008515957A
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Japanese (ja)
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JP2008545798A (ja
JP2008545798A5 (https=
Inventor
シリ チェン，
ロンリャン ルー，
ユーシェン ウー，
チアチェン チョウ，
ロジャー ハンゼルマン，
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Melinta Subsidiary Corp
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Rib X Pharmaceuticals Inc
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Publication of JP2008545798A5 publication Critical patent/JP2008545798A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • C07F7/0814—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring is substituted at a C ring atom by Si

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2008515957A 2005-06-08 2006-06-08 トリアゾール類の合成方法 Expired - Fee Related JP5534497B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68899005P 2005-06-08 2005-06-08
US60/688,990 2005-06-08
PCT/US2006/022424 WO2006133397A2 (en) 2005-06-08 2006-06-08 Process for the synthesis of triazoles

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013077419A Division JP5923457B2 (ja) 2005-06-08 2013-04-03 トリアゾール類の合成方法

Publications (3)

Publication Number Publication Date
JP2008545798A JP2008545798A (ja) 2008-12-18
JP2008545798A5 JP2008545798A5 (https=) 2013-12-19
JP5534497B2 true JP5534497B2 (ja) 2014-07-02

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JP2008515957A Expired - Fee Related JP5534497B2 (ja) 2005-06-08 2006-06-08 トリアゾール類の合成方法
JP2013077419A Active JP5923457B2 (ja) 2005-06-08 2013-04-03 トリアゾール類の合成方法

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Country Status (7)

Country Link
US (3) US8399660B2 (https=)
EP (1) EP1904489B1 (https=)
JP (2) JP5534497B2 (https=)
KR (1) KR101394307B1 (https=)
AT (1) ATE496914T1 (https=)
DE (1) DE602006019870D1 (https=)
WO (1) WO2006133397A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013129680A (ja) * 2005-06-08 2013-07-04 Rib-X Pharmaceuticals Inc トリアゾール類の合成方法

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WO2007133803A2 (en) * 2006-05-15 2007-11-22 Rib-X Pharmaceuticals, Inc. Treatment of mycobacterial infections
WO2010005127A2 (en) * 2008-07-09 2010-01-14 Postech Academy-Industry Foundation Heterogeneous copper nanocatalyst and manufacturing methods thereof
WO2010047737A2 (en) 2008-09-02 2010-04-29 Micurx Pharmaceuticals, Inc. Antimicrobial indoline compounds for treatment of bacterial infections
CN103379917B (zh) * 2010-11-01 2016-10-12 梅琳塔治疗公司 药物组合物
US9126991B2 (en) 2012-10-04 2015-09-08 Hui-Yin Li Radezolid salts and polymorphic forms thereof
CN107205989A (zh) 2014-11-14 2017-09-26 梅琳塔治疗公司 治疗、预防或降低皮肤感染风险的方法
WO2016088103A1 (en) * 2014-12-05 2016-06-09 Sun Pharmaceutical Industries Limited A process for the preparation of tedizolid phosphate
US20170333400A1 (en) * 2016-05-17 2017-11-23 Melinta Therapeutics, Inc. Topical formulations of biaryl heterocyclic compounds and methods of use thereof
CN106749074A (zh) * 2016-11-14 2017-05-31 沈阳药科大学 一种联芳基噁唑烷酮中间体的制备方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013129680A (ja) * 2005-06-08 2013-07-04 Rib-X Pharmaceuticals Inc トリアゾール類の合成方法

Also Published As

Publication number Publication date
US8399660B2 (en) 2013-03-19
US20150158827A1 (en) 2015-06-11
WO2006133397A2 (en) 2006-12-14
US20140031402A1 (en) 2014-01-30
EP1904489B1 (en) 2011-01-26
ATE496914T1 (de) 2011-02-15
US8796465B2 (en) 2014-08-05
JP2008545798A (ja) 2008-12-18
KR20080020669A (ko) 2008-03-05
KR101394307B1 (ko) 2014-05-13
US20100234615A1 (en) 2010-09-16
WO2006133397A3 (en) 2007-05-24
DE602006019870D1 (de) 2011-03-10
EP1904489A2 (en) 2008-04-02
US9376400B2 (en) 2016-06-28
JP5923457B2 (ja) 2016-05-24
JP2013129680A (ja) 2013-07-04

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