JP5468112B2 - 携帯型注入ポンプにおける閉塞を検出する方法および装置 - Google Patents
携帯型注入ポンプにおける閉塞を検出する方法および装置 Download PDFInfo
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
- A61M5/16854—Monitoring, detecting, signalling or eliminating infusion flow anomalies by monitoring line pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M2005/14264—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with means for compensating influence from the environment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
- A61M2005/16863—Occlusion detection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/18—General characteristics of the apparatus with alarm
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/332—Force measuring means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/70—General characteristics of the apparatus with testing or calibration facilities
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
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- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
102,203,2304 親ねじ
103 駆動ナット
104 ピストン
105,206,301,715,2308 貯槽
106,207,2310 注入セット
107,208,302,401 筐体
110 掛止アーム
201a,432,2302 駆動軸
202,906,2405 歯車
204 プランジャ滑動部
205 貯槽ピストン
209,2305 軸受
303,1404,1802 ピストン部材
304 ピストンヘッド
305 回転駆動ねじ
306 駆動モータ
402 下方区間
404 駆動ねじ(第1駆動部材)
405 プランジャ滑動部(第2駆動部材)
406 バイアルまたは貯槽
407 プランジャまたはピストン組立体
409 Oリング封止体
410 回転防止キー
412 システムコンプライアンス取付け
420 電源
422 電子制御回路
424 雌部分
426 雄部分
428 ピストン組立体の端面
430 プランジャ滑動部の端部
431 コネクタ
433 コネクタのねじ山
434 回転防止スロット
436 長方形タブ
440 貯槽ピストン組立体の移動軸
442 リング(カラー)
701 注入ポンプ
706 センサ
711,2306 滑動部
712 雄ねじ山
713 雌ねじ山
714,2307 ストッパ
2303 歯車の組
2309 管系
2402 モータケース
2403,2404 近位軸受
2406 梁
2407 歪みゲージセンサ
2408 モータ軸
2409 筐体繋止点
2410 繋止点
2701,2901 開始ブロック
2702 第1ポンプ値を測定するブロック
2703 第2ポンプ値を測定するブロック
2704,2905 閉塞を検出するブロック
2705,2906 閉塞を示すブロック
2706,2907 注入を継続するブロック
2902 一連のポンプ値を測定するブロック
2903 一連のポンプ値のピーク値を決定するブロック
2904 ピーク値よりも後の第2値を決定するブロック
Claims (14)
- 貯槽からユーザの体内に流体を注入するために、前記貯槽に結合した1つまたは複数の駆動列構成要素とモータとを備える駆動機構を有する注入ポンプ内の閉塞を検出する方法であって、
前記駆動列構成要素の1つまたは前記モータに関連する第1パラメータを測定する段階を含み、前記第1パラメータは、モータトルクまたはモータ駆動計数のいずれかであり、
前記方法は、
前記駆動列構成要素の1つまたは前記モータに関連する別の第2パラメータを測定する段階を含み、前記第2パラメータは、駆動電流、駆動電圧、モータ駆動時間、モータ惰性回転時間、送達パルスエネルギー、モータ惰性回転計数、およびデルタエンコーダ計数のうちの1つであり、
前記方法は、
第1の組み合わせ値を生成するように、前記第1パラメータを前記第2パラメータと組み合わせる段階と、
前記第1の組み合わせ値を使用することによって、閉塞が発生したかどうかを判定する段階と
を含み、
前記第1パラメータを前記第2パラメータと組み合わせる段階は、
前記第1パラメータおよび前記第2パラメータのうち1つまたは複数を正規化因子で乗算する段階と、
オフセット値を加算する段階とを含むことを特徴とする方法。 - 前記第1パラメータを前記第2パラメータと組み合わせる段階は、前記第1パラメータを前記第2パラメータに加算する段階を含むことを特徴とする請求項1に記載の方法。
- 前記第1パラメータを前記第2パラメータと組み合わせる段階は、前記第1パラメータを前記第2パラメータで乗算する段階を含むことを特徴とする請求項1に記載の方法。
- 前記閉塞が発生したかどうかを判定する段階は、前記第1の組み合わせ値が閾値を超えた場合に、閉塞が発生したことを示す段階を含む、ことを特徴とする請求項1に記載の方法。
- 前記駆動列構成要素の1つまたは前記モータに関連する先行する第1パラメータおよび先行する第2パラメータを取り出す段階と、
第2の組み合わせ値を生成するように、前記先行する第1パラメータを前記先行する第2パラメータと組み合わせる段階とを含み、
前記第1の組み合わせ値を使用することによって、閉塞が発生したかどうかを判定する段階は、前記第1の組み合わせ値および前記第2の組み合わせ値を使用して線の傾きを計算する段階と、前記傾きが傾き閾値を超えた場合に閉塞が発生したことを示す段階とをさらに含むことを特徴とする請求項1に記載の方法。 - 1つまたは複数の先行する第1パラメータ、および1つまたは複数の先行する第2パラメータを取り出す段階と、
1つまたは複数の先行する組み合わせ値を生成するように、前記1つまたは複数の先行する第1パラメータを前記1つまたは複数の先行する第2パラメータと組み合わせる段階と、
前記1つまたは複数の先行する組み合わせ値から先行する組み合わせ値の平均を計算する段階と、
前記第1の組み合わせ値が前記先行する組み合わせ値の平均とは異なる所定量よりも大きいかどうかを判定することによって、閉塞が発生したかどうかを判定する段階とをさらに含むことを特徴とする請求項1に記載の方法。 - 前記第1の組み合わせ値を使用することによって、閉塞が発生したかどうかを判定する段階は、
前記第1の組み合わせ値を使用して、閉塞が発生したかどうかについて第1の計算を行う段階と、
前記第1の計算とは別に、第2の組み合わせ値を使用して、閉塞が発生したかどうかについての第2計算を行う段階と、前記第2の組み合わせ値は、前記第1の組み合わせ値と同じまたは異なり、
前記第1の計算および第2の計算のいずれかまたは両方が、閉塞が発生したことを示した場合、閉塞が発生したと判定する段階とを含むことを特徴とする請求項1に記載の方法。 - 貯槽からユーザの体内に流体を注入する注入ポンプであって、
筐体と、
前記筐体内に収容された1つまたは複数の駆動列構成要素およびモータを備えるとともに、前記貯槽から流体通路を通して前記ユーザの体内に流体を送達するように、前記貯槽と動作可能に結合された駆動機構と、
前記駆動列構成要素の1つまたは前記モータに関連する第1パラメータと、前記駆動列構成要素の1つまたは前記モータに関連する別の第2パラメータとを測定するように構成された1つまたは複数の電子構成要素と、
前記筐体内に収容され、かつ前記第1パラメータを前記第2パラメータと組み合わせて組み合わせ値を生成し、前記組み合わせ値を使用して、前記注入ポンプの流体通路内で閉塞が発生したかどうかを判定するように構成されたプロセッサとを備え、
前記第1パラメータは、モータトルクまたはモータ駆動計数のいずれかであり、前記第2パラメータは、駆動電流、駆動電圧、モータ駆動時間、モータ惰性回転時間、送達パルスエネルギー、モータ惰性回転計数、およびデルタエンコーダ計数のうちの1つであり、
前記プロセッサは、前記第1パラメータおよび前記第2パラメータのうち1つまたは複数を正規化因子で乗算して、オフセット値を加算するようにさらに構成されることを特徴とする注入ポンプ。 - 前記組み合わせ値の生成は、前記第1パラメータを前記第2パラメータに加算することを含むことを特徴とする請求項8に記載の注入ポンプ。
- 前記組み合わせ値の生成は、前記第1パラメータを前記第2パラメータで乗算することを含むことを特徴とする請求項8に記載の注入ポンプ。
- 前記プロセッサは、最大測定閾値方法、傾き閾値方法、分散監視方法、およびこれらの組み合わせからなる群から選択された閉塞検出方法を使用することによって、閉塞が発生したかどうかを判定するようにさらに構成されることを特徴とする請求項8に記載の注入ポンプ。
- 1つまたは複数の駆動列構成要素とモータとを備える駆動機構を有する注入ポンプ内の閉塞を検出する閉塞検出システムであって、
前記駆動列構成要素の1つまたは前記モータに関連する第1パラメータを測定する手段を備え、前記第1パラメータは、モータトルクまたはモータ駆動計数のいずれかであり、
前記閉塞検出システムは、
前記駆動列構成要素の1つまたは前記モータに関連する第2パラメータを測定する手段を備え、前記第2パラメータは、駆動電流、駆動電圧、モータ駆動時間、モータ惰性回転時間、送達パルスエネルギー、モータ惰性回転計数、およびデルタエンコーダ計数のうちの1つであり、
前記閉塞検出システムは、
組み合わせ値を生成するように、前記第1パラメータを前記第2パラメータと組み合わせる手段を具備し、前記組み合わせる手段は、前記第1パラメータおよび前記第2パラメータのうち1つまたは複数を正規化因子で乗算して、オフセット値を加算するように構成され、
前記閉塞検出システムは、
前記組み合わせ値を使用することによって、前記注入ポンプ内で閉塞が発生したかどうかを判定する手段を備えることを特徴とする閉塞検出システム。 - 前記組み合わせ値の生成は、前記第1パラメータを前記第2パラメータに加算することを含むことを特徴とする請求項12に記載の閉塞検出システム。
- 前記組み合わせ値の生成は、前記第1パラメータを前記第2パラメータで乗算することを含むことを特徴とする請求項12に記載の閉塞検出システム。
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US11/323,104 | 2005-12-30 | ||
US11/323,104 US7621893B2 (en) | 1998-10-29 | 2005-12-30 | Methods and apparatuses for detecting occlusions in an ambulatory infusion pump |
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US7766873B2 (en) | 1998-10-29 | 2010-08-03 | Medtronic Minimed, Inc. | Method and apparatus for detecting occlusions in an ambulatory infusion pump |
US7621893B2 (en) | 1998-10-29 | 2009-11-24 | Medtronic Minimed, Inc. | Methods and apparatuses for detecting occlusions in an ambulatory infusion pump |
JP4681795B2 (ja) | 2001-05-18 | 2011-05-11 | デカ・プロダクツ・リミテッド・パートナーシップ | 流体ポンプ用注入セット |
US8034026B2 (en) | 2001-05-18 | 2011-10-11 | Deka Products Limited Partnership | Infusion pump assembly |
US9955994B2 (en) | 2002-08-02 | 2018-05-01 | Flowcardia, Inc. | Ultrasound catheter having protective feature against breakage |
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