JP5425058B2 - アルギン酸塩体を含む胃内滞留型システム - Google Patents

アルギン酸塩体を含む胃内滞留型システム Download PDF

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Publication number
JP5425058B2
JP5425058B2 JP2010510670A JP2010510670A JP5425058B2 JP 5425058 B2 JP5425058 B2 JP 5425058B2 JP 2010510670 A JP2010510670 A JP 2010510670A JP 2010510670 A JP2010510670 A JP 2010510670A JP 5425058 B2 JP5425058 B2 JP 5425058B2
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Prior art keywords
calcium
gastroretentive
gastric retention
zinc
mass
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Expired - Fee Related
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JP2010510670A
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Japanese (ja)
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JP2010529056A (ja
JP2010529056A5 (https=
Inventor
アスムッセン，ボードー
シラー，クリスティアーネ
ヴァイチース，ヴェルナー
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エルテーエス ローマン テラピー−ジステーメ アーゲー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2010510670A 2007-06-04 2008-05-27 アルギン酸塩体を含む胃内滞留型システム Expired - Fee Related JP5425058B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102007026037.9 2007-06-04
DE102007026037A DE102007026037A1 (de) 2007-06-04 2007-06-04 Gastroretentives System mit Alginat-Körper
PCT/EP2008/004188 WO2008148478A2 (de) 2007-06-04 2008-05-27 Gastroretentives system mit alginat-körper

Publications (3)

Publication Number Publication Date
JP2010529056A JP2010529056A (ja) 2010-08-26
JP2010529056A5 JP2010529056A5 (https=) 2010-10-07
JP5425058B2 true JP5425058B2 (ja) 2014-02-26

Family

ID=39942026

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010510670A Expired - Fee Related JP5425058B2 (ja) 2007-06-04 2008-05-27 アルギン酸塩体を含む胃内滞留型システム

Country Status (14)

Country Link
US (1) US20100129445A1 (https=)
EP (2) EP2497465A3 (https=)
JP (1) JP5425058B2 (https=)
KR (1) KR101268215B1 (https=)
CN (1) CN102215826A (https=)
AU (1) AU2008258881B2 (https=)
CA (1) CA2689049C (https=)
DE (1) DE102007026037A1 (https=)
IL (1) IL202518A0 (https=)
MX (1) MX2009013086A (https=)
NZ (1) NZ581740A (https=)
RU (1) RU2468790C2 (https=)
WO (1) WO2008148478A2 (https=)
ZA (1) ZA200908355B (https=)

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KR101118794B1 (ko) * 2009-11-10 2012-06-13 동아제약주식회사 비스포스포네이트를 함유하는 약학 조성물
WO2012083017A2 (en) 2010-12-16 2012-06-21 Celgene Corporation Controlled release oral dosage forms of poorly soluble drugs and uses thereof
US9532977B2 (en) 2010-12-16 2017-01-03 Celgene Corporation Controlled release oral dosage forms of poorly soluble drugs and uses thereof
DE102011051653A1 (de) * 2011-07-07 2013-01-10 Lts Lohmann Therapie-Systeme Ag Quellfähige Manteltablette
DK2858604T3 (da) 2012-06-07 2024-05-21 Epitomee Medical Ltd Ekspanderet anordning
EP2887925B1 (en) * 2012-08-27 2017-02-22 Evonik Röhm GmbH Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol
WO2014032676A1 (en) * 2012-09-03 2014-03-06 S-Biotek Holding Aps A solid oral formulation for treatment and/or prevention of overweight and/or for stabilizing blood sugar levels in an individual.
WO2015083171A1 (en) * 2013-12-05 2015-06-11 Tulip Medical Ltd. Retentive devices and systems for in-situ release of pharmaceutical active agents
WO2017083348A1 (en) 2015-11-11 2017-05-18 Celgene Corporation Controlled release oral dosage forms of poorly soluble drugs and uses thereof
CN108721246B (zh) * 2018-05-29 2021-06-25 王喆明 高分子材料构建的多单元超长效口服制剂及其制备方法
US11511093B2 (en) 2019-10-11 2022-11-29 Wonkwang University Center for Industry Academy Cooperation Gastroretentive drug delivery device having expandable structure and manufacturing method therefor
KR102278915B1 (ko) 2019-10-24 2021-07-19 중앙대학교 산학협력단 다공성 하이드로겔을 유효성분으로 함유하는 위 체류 및 약물 방출 제어형 경구용 제제
EP4477215A3 (en) 2020-12-08 2025-02-19 Ruminant Biotech Corp Limited Improvements to devices and methods for delivery of substances to animals

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US4207890A (en) 1977-01-04 1980-06-17 Mcneilab, Inc. Drug-dispensing device and method
US4735804A (en) * 1985-05-10 1988-04-05 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US4695463A (en) * 1985-05-24 1987-09-22 Warner-Lambert Company Delivery system for active ingredients and preparation thereof
US4816262A (en) 1986-08-28 1989-03-28 Universite De Montreal Controlled release tablet
IL87710A (en) 1987-09-18 1992-06-21 Ciba Geigy Ag Covered floating retard form for controlled release in gastric juice
DE3803482A1 (de) * 1988-02-05 1989-08-17 Lohmann Therapie Syst Lts Schwimmfaehiges orales therapeutisches system
US4983401A (en) 1989-05-22 1991-01-08 Kinaform Technology, Inc. Sustained release pharmaceutical preparations having pH controlled membrane coatings
US5198227A (en) 1990-01-22 1993-03-30 Mcneil-Ppc, Inc. Dual subcoated simulated capsule medicament
US5198229A (en) * 1991-06-05 1993-03-30 Alza Corporation Self-retaining gastrointestinal delivery device
ATE133331T1 (de) 1991-11-13 1996-02-15 Glaxo Canada Vorrichtung zur kontrollierten wirkstoffreigabe
DE69423643T2 (de) * 1993-10-29 2000-09-07 R.P. Scherer Corp., Troy Schäumende gelatinkapselfüllung
DE4419818C2 (de) 1994-06-07 1998-10-22 Lohmann Therapie Syst Lts Wirkstoffträger zur kontrollierten Freisetzung von Wirkstoffen im Gastrointestinaltrakt mit verzögerter Pyloruspassage und Verfahren zur Herstellung desselben
DE4431653C2 (de) 1994-09-06 2000-01-20 Lohmann Therapie Syst Lts Manteltablette zur kontrollierten Freisetzung von Wirkstoffen, ein Verfahren zu ihrer Herstellung und ihre Verwendung
DE19537090A1 (de) 1995-10-05 1997-04-10 Lohmann Therapie Syst Lts Osmotische Vorrichtung zur kontinuierlichen Freisetzung von Wirkstoffen in die Flüssigkeiten des Gastrointestinaltraktes
US20020002364A1 (en) * 1995-10-05 2002-01-03 Karsten Cremer Osmotic device for the continuous release of active compounds into the fluids of the gastrointestinal tract
FR2784583B1 (fr) * 1998-10-16 2002-01-25 Synthelabo Composition pharmaceutique a residence gastrique et a liberation controlee
US6797283B1 (en) 1998-12-23 2004-09-28 Alza Corporation Gastric retention dosage form having multiple layers
US6497902B1 (en) * 1999-12-01 2002-12-24 The Regents Of The University Of Michigan Ionically crosslinked hydrogels with adjustable gelation time
US6488962B1 (en) 2000-06-20 2002-12-03 Depomed, Inc. Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
JP2004501190A (ja) 2000-06-23 2004-01-15 テバ　ファーマシューティカル　インダストリーズ　リミティド 治療薬の胃部保留および制御された放出のための急速膨張する組成物とその組成物を含む剤形
DE60212475T2 (de) * 2001-03-14 2007-07-05 Pfizer Products Inc., Groton Pharmazeutische Tablette und ein Verfahren zu ihrer Herstellung
EP1245227A1 (en) 2001-03-31 2002-10-02 Jagotec Ag A pharmaceutical tablet system that floats in the stomach for programmed release of active substance and process of producing buoyant material contained in same
MXPA03012041A (es) 2001-07-04 2004-03-26 Sun Pharmaceutical Ind Ltd Sistema de administracion controlada de farmacos de retencion gastrica.
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WO2004002445A2 (en) 2002-06-26 2004-01-08 Cadila Healthcare Limited Novel floating dosage form
US20060003003A1 (en) 2004-06-28 2006-01-05 Bakker Johan A Oral sustained release formulation of tedisamil with gastric retention properties

Also Published As

Publication number Publication date
KR20100028621A (ko) 2010-03-12
WO2008148478A3 (de) 2009-04-09
CA2689049C (en) 2014-07-08
CA2689049A1 (en) 2008-12-11
AU2008258881B2 (en) 2013-12-19
EP2155172A2 (de) 2010-02-24
JP2010529056A (ja) 2010-08-26
EP2497465A3 (de) 2012-11-21
RU2468790C2 (ru) 2012-12-10
ZA200908355B (en) 2010-07-28
MX2009013086A (es) 2010-01-18
WO2008148478A8 (de) 2009-02-05
EP2497465A2 (de) 2012-09-12
WO2008148478A2 (de) 2008-12-11
NZ581740A (en) 2011-05-27
US20100129445A1 (en) 2010-05-27
DE102007026037A1 (de) 2008-12-11
AU2008258881A1 (en) 2008-12-11
IL202518A0 (en) 2010-06-30
RU2009147730A (ru) 2011-06-27
KR101268215B1 (ko) 2013-05-31
CN102215826A (zh) 2011-10-12

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