JP5345403B2 - １−ホルムアミド−３，５−ジメチルアダマンタンの製造方法 - Google Patents

１−ホルムアミド−３，５−ジメチルアダマンタンの製造方法 Download PDF

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Publication number
JP5345403B2
JP5345403B2 JP2008556686A JP2008556686A JP5345403B2 JP 5345403 B2 JP5345403 B2 JP 5345403B2 JP 2008556686 A JP2008556686 A JP 2008556686A JP 2008556686 A JP2008556686 A JP 2008556686A JP 5345403 B2 JP5345403 B2 JP 5345403B2
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Prior art keywords
dimethyladamantane
formamide
acid
formamidation
producing
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JP2008556686A
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Japanese (ja)
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JP2009528309A (ja
JP2009528309A5 (enExample
Inventor
シュライナー，ペーター・エール
フォーキン，アンドレイ・アー
ワンカ，ルーカス
ウルフ，デレック・エム
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メルツ・ファルマ・ゲーエムベーハー・ウント・コー・カーゲーアーアー
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2008556686A 2006-03-01 2007-02-20 １−ホルムアミド−３，５−ジメチルアダマンタンの製造方法 Active JP5345403B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102006009279A DE102006009279A1 (de) 2006-03-01 2006-03-01 Verfahren zur Herstellung von 1-Formamido-3,5-dimethyladamantan
DE102006009279.1 2006-03-01
PCT/EP2007/001433 WO2007101536A1 (de) 2006-03-01 2007-02-20 Verfahren zur herstellung von 1-formamido-3,5-dimethyladamantan

Publications (3)

Publication Number Publication Date
JP2009528309A JP2009528309A (ja) 2009-08-06
JP2009528309A5 JP2009528309A5 (enExample) 2010-04-08
JP5345403B2 true JP5345403B2 (ja) 2013-11-20

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ID=38197988

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008556686A Active JP5345403B2 (ja) 2006-03-01 2007-02-20 １−ホルムアミド−３，５−ジメチルアダマンタンの製造方法

Country Status (7)

Country Link
US (1) US8138375B2 (enExample)
EP (1) EP1989175B1 (enExample)
JP (1) JP5345403B2 (enExample)
DE (1) DE102006009279A1 (enExample)
ES (1) ES2392550T3 (enExample)
RU (1) RU2455281C2 (enExample)
WO (1) WO2007101536A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2507085T3 (es) * 2008-03-20 2014-10-14 Merz Pharma Gmbh & Co. Kgaa Proceso para la fabricación de Memantina y producto intermedio
EP2103597A1 (en) * 2008-03-20 2009-09-23 Merz Pharma GmbH & Co.KGaA Process for the manufacture of memantine and intermediate product
EP2373612B1 (en) 2008-12-17 2013-04-17 Merz Pharma GmbH & Co. KGaA Method for producing memantine
JP5548702B2 (ja) * 2009-01-21 2014-07-16 メルツ・ファルマ・ゲゼルシヤフト・ミト・ベシュレンクテル・ハフツング・ウント・コンパニー・コマンデイトゲゼルシヤフト・アウフ・アクティーン メマンチンの製造方法
JP5778148B2 (ja) 2009-08-04 2015-09-16 メルク パテント ゲーエムベーハー 多環式炭水化物を含む電子デバイス
JP2013180983A (ja) * 2012-03-01 2013-09-12 Tokyo Univ Of Agriculture & Technology Ｎ置換アミド化合物の製造方法
RU2549901C1 (ru) * 2013-12-30 2015-05-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Кубанский государственный университет" (ФГБОУ ВПО "КубГУ") Способ получения n-адамантилированных амидов
EP4005565A1 (en) 2020-11-30 2022-06-01 Merz Pharmaceuticals GmbH Novel uses of adamantane derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2318461A1 (de) 1973-04-12 1974-10-31 Merz & Co Verfahren zur herstellung von 1,3,5trisubstituierten adamanta-verbindungen
JPS63159330A (ja) * 1986-12-23 1988-07-02 Kawasaki Steel Corp １，３−ジメチルアダマンタンの製造方法
JPS63295519A (ja) * 1987-05-27 1988-12-01 Kawasaki Steel Corp １，３−ジメチルアダマンタンの製造方法
SU1643528A1 (ru) * 1988-10-03 1991-04-23 Научно-производственное объединение "Комплекс" Способ получени 1-ацетаминоадамантана
DE10299048I2 (de) 1989-04-14 2006-07-13 Merz Pharma Gmbh & Co Kgaa Verwendung von Adamantan-Derivaten zur Pr{vention und Behandlung der cerebralen Isch{mie
US5117056A (en) 1990-12-21 1992-05-26 Air Products And Chemicals, Inc. Preparation of N-(1-alkoxyalkyl)formamide and bis formamides
RU2246482C2 (ru) * 2002-12-25 2005-02-20 ООО "Циклан" Способ получения гидрохлорида 1-амино-3,5-диметиладамантана
CN100345819C (zh) 2003-07-01 2007-10-31 北京德众万全药物技术开发有限公司 一种取代的金刚烷胺类化合物或其盐的制备方法
US20080275112A1 (en) 2004-07-23 2008-11-06 Schreiner Peter R Invention Concerning Aminoadamantane Compounds

Also Published As

Publication number Publication date
DE102006009279A1 (de) 2007-09-06
US8138375B2 (en) 2012-03-20
US20090299097A1 (en) 2009-12-03
JP2009528309A (ja) 2009-08-06
RU2455281C2 (ru) 2012-07-10
WO2007101536A1 (de) 2007-09-13
EP1989175B1 (de) 2012-09-19
RU2008138891A (ru) 2010-04-10
EP1989175A1 (de) 2008-11-12
ES2392550T3 (es) 2012-12-11

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