JP5253148B2 - 脂質二重層への分子の送達 - Google Patents
脂質二重層への分子の送達 Download PDFInfo
- Publication number
- JP5253148B2 JP5253148B2 JP2008502471A JP2008502471A JP5253148B2 JP 5253148 B2 JP5253148 B2 JP 5253148B2 JP 2008502471 A JP2008502471 A JP 2008502471A JP 2008502471 A JP2008502471 A JP 2008502471A JP 5253148 B2 JP5253148 B2 JP 5253148B2
- Authority
- JP
- Japan
- Prior art keywords
- probe
- lipid bilayer
- membrane protein
- carrier surface
- planar lipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Sustainable Development (AREA)
- General Engineering & Computer Science (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0505971.2 | 2005-03-23 | ||
| GBGB0505971.2A GB0505971D0 (en) | 2005-03-23 | 2005-03-23 | Delivery of molecules to a lipid bilayer |
| PCT/GB2006/001057 WO2006100484A2 (en) | 2005-03-23 | 2006-03-22 | Deliver of molecules to a li id bila |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008537106A JP2008537106A (ja) | 2008-09-11 |
| JP2008537106A5 JP2008537106A5 (enExample) | 2009-10-15 |
| JP5253148B2 true JP5253148B2 (ja) | 2013-07-31 |
Family
ID=34531741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008502471A Expired - Fee Related JP5253148B2 (ja) | 2005-03-23 | 2006-03-22 | 脂質二重層への分子の送達 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7939270B2 (enExample) |
| EP (1) | EP1861071B1 (enExample) |
| JP (1) | JP5253148B2 (enExample) |
| AT (1) | ATE473438T1 (enExample) |
| DE (1) | DE602006015292D1 (enExample) |
| GB (1) | GB0505971D0 (enExample) |
| WO (1) | WO2006100484A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8627531B2 (en) | 2001-09-04 | 2014-01-14 | Sharp Kabushiki Kaisha | Vacuum cleaner and device having ion generator |
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| US9233846B2 (en) | 2005-10-14 | 2016-01-12 | The Regents Of The University Of California | Formation and encapsulation of molecular bilayer and monolayer membranes |
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| GB2447043A (en) * | 2007-02-20 | 2008-09-03 | Oxford Nanolabs Ltd | Lipid bilayer sensor system |
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| DE112008003078B4 (de) | 2007-11-30 | 2018-11-29 | Electronic Bio Sciences, Llc | Verfahren und Vorrichtung zur einseitigen Doppelschichtbildung |
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| US8324914B2 (en) | 2010-02-08 | 2012-12-04 | Genia Technologies, Inc. | Systems and methods for characterizing a molecule |
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| US9678055B2 (en) | 2010-02-08 | 2017-06-13 | Genia Technologies, Inc. | Methods for forming a nanopore in a lipid bilayer |
| WO2012033524A2 (en) | 2010-09-07 | 2012-03-15 | The Regents Of The University Of California | Control of dna movement in a nanopore at one nucleotide precision by a processive enzyme |
| WO2012083249A2 (en) | 2010-12-17 | 2012-06-21 | The Trustees Of Columbia University In The City Of New York | Dna sequencing by synthesis using modified nucleotides and nanopore detection |
| GB2500360B (en) | 2010-12-22 | 2019-10-23 | Genia Tech Inc | Nanopore-based single DNA molecule characterization, identification and isolation using speed bumps |
| GB201100516D0 (en) | 2011-01-12 | 2011-02-23 | Isis Innovation | Method using fluorinated amphiphiles |
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| US9110478B2 (en) | 2011-01-27 | 2015-08-18 | Genia Technologies, Inc. | Temperature regulation of measurement arrays |
| JP6169976B2 (ja) | 2011-02-11 | 2017-07-26 | オックスフォード ナノポール テクノロジーズ リミテッド | 変異体細孔 |
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| AU2012264497B2 (en) | 2011-05-27 | 2017-06-15 | Oxford Nanopore Technologies Limited | Coupling method |
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| EP2578207A3 (en) * | 2011-10-05 | 2015-10-07 | Jacob J. Schmidt | Masking apertures enabling automation and solution exchange in sessile droplet lipid bilayers |
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| US9617591B2 (en) | 2011-12-29 | 2017-04-11 | Oxford Nanopore Technologies Ltd. | Method for characterising a polynucleotide by using a XPD helicase |
| WO2013098562A2 (en) | 2011-12-29 | 2013-07-04 | Oxford Nanopore Technologies Limited | Enzyme method |
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| US10739341B2 (en) | 2012-02-15 | 2020-08-11 | Oxford Nanopore Technologies Limited | Aptamer method |
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| ES2906186T3 (es) | 2012-04-09 | 2022-04-13 | Univ Columbia | Método para la preparación de nanoporo y usos del mismo |
| KR102083695B1 (ko) | 2012-04-10 | 2020-03-02 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 돌연변이체 리세닌 기공 |
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| WO2013191793A1 (en) | 2012-06-20 | 2013-12-27 | The Trustees Of Columbia University In The City Of New York | Nucleic acid sequencing by nanopore detection of tag molecules |
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| US10732183B2 (en) | 2013-03-15 | 2020-08-04 | The Trustees Of Columbia University In The City Of New York | Method for detecting multiple predetermined compounds in a sample |
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| KR102329836B1 (ko) | 2015-01-26 | 2021-11-19 | 셀렉티스 | 암 면역치료를 위한 항-CLL1 특이적 단일-체인 키메라 항원 수용체들(scCARS) |
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| US11169138B2 (en) | 2015-04-14 | 2021-11-09 | Katholieke Universiteit Leuven | Nanopores with internal protein adaptors |
| US10976300B2 (en) | 2015-12-08 | 2021-04-13 | Katholieke Universiteit Leuven | Modified nanopores, compositions comprising the same, and uses thereof |
| CN116200476A (zh) | 2016-03-02 | 2023-06-02 | 牛津纳米孔科技公开有限公司 | 靶分析物测定方法、突变CsgG单体及其构筑体、及聚核苷酸和寡聚孔 |
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| CN109196116B (zh) | 2016-05-25 | 2022-09-27 | 牛津纳米孔科技公开有限公司 | 一种表征靶多核苷酸的方法 |
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| JP2018059786A (ja) * | 2016-10-04 | 2018-04-12 | 住友化学株式会社 | 嗅覚受容体複合体を用いた標的物質の検出装置及び検出方法並びに該検出装置の製造方法 |
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| CN119530363A (zh) | 2017-02-10 | 2025-02-28 | 牛津纳米孔科技公开有限公司 | 修饰的纳米孔、包含其的组合物及其用途 |
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| CN110914290A (zh) | 2017-06-30 | 2020-03-24 | 弗拉芒区生物技术研究所 | 新颖蛋白孔 |
| EP4303317A3 (en) * | 2017-10-23 | 2024-04-24 | F. Hoffmann-La Roche AG | Removing and reinserting protein nanopores in a membrane using osmotic imbalance |
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| GB201807793D0 (en) | 2018-05-14 | 2018-06-27 | Oxford Nanopore Tech Ltd | Method |
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| CN121090823A (zh) | 2019-03-12 | 2025-12-09 | 牛津纳米孔科技公开有限公司 | 纳米孔感测装置、组件和操作方法 |
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| KR20250048551A (ko) | 2022-08-09 | 2025-04-09 | 옥스포드 나노포어 테크놀로지즈 피엘씨 | 신규 포어 |
| GB202211607D0 (en) | 2022-08-09 | 2022-09-21 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
| KR20250096716A (ko) | 2022-10-28 | 2025-06-27 | 옥스포드 나노포어 테크놀로지즈 피엘씨 | 포어 단량체 및 포어 |
| GB202216162D0 (en) | 2022-10-31 | 2022-12-14 | Oxford Nanopore Tech Plc | Method |
| GB202216905D0 (en) | 2022-11-11 | 2022-12-28 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
| WO2024165853A1 (en) | 2023-02-07 | 2024-08-15 | Oxford University Innovation Limited | Method of characterising a peptide, polypeptide or protein using a nanopore |
| GB202304324D0 (en) | 2023-03-24 | 2023-05-10 | Oxford Nanopore Tech Plc | Method and kits |
| GB202305524D0 (en) | 2023-04-14 | 2023-05-31 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
| GB202307141D0 (en) | 2023-05-12 | 2023-06-28 | Oxford Nanopore Tech Plc | Modified helicases |
| GB202307486D0 (en) | 2023-05-18 | 2023-07-05 | Oxford Nanopore Tech Plc | Method |
| GB202312709D0 (en) | 2023-08-18 | 2023-10-04 | Univ Oxford Innovation Ltd | Nanopore |
| GB202313035D0 (en) | 2023-08-25 | 2023-10-11 | Univ Oxford Innovation Ltd | Power unit |
| GB202315935D0 (en) | 2023-10-18 | 2023-11-29 | Oxford Nanopore Tech Ltd | Novel enzymes |
| GB202317028D0 (en) | 2023-11-06 | 2023-12-20 | Oxford Nanopore Tech Ltd | Method |
| WO2025160387A1 (en) * | 2024-01-24 | 2025-07-31 | The Rockefeller University | Microscope for freestanding bilayer illumination |
| GB202405960D0 (en) | 2024-04-29 | 2024-06-12 | Oxford Nanopore Tech Plc | Photo-active conjugates and their uses |
| GB202407055D0 (en) | 2024-05-17 | 2024-07-03 | Oxford Nanopore Tech Plc | Enhanced polynucleotide sequencing |
| GB202407247D0 (en) | 2024-05-21 | 2024-07-03 | Oxford Nanopore Tech Plc | Method |
| GB202407228D0 (en) | 2024-05-21 | 2024-07-03 | Oxford Nanopore Tech Plc | Method |
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| US3799743A (en) | 1971-11-22 | 1974-03-26 | Alexander James | Stable lysis responsive lipid bilayer |
| US6327410B1 (en) * | 1997-03-14 | 2001-12-04 | The Trustees Of Tufts College | Target analyte sensors utilizing Microspheres |
| GB9712386D0 (en) * | 1997-06-14 | 1997-08-13 | Univ Coventry | Biosensor |
| WO1999041401A1 (en) * | 1998-02-17 | 1999-08-19 | University Of Wales College Of Medicine | Method and apparatus for introducing substances into the cell plasma membrane and/or cytosol |
| CN1325405A (zh) * | 1998-08-31 | 2001-12-05 | 格莱风科学公司 | 膜多肽的脂基质协助的化学结合和合成 |
| JP3665720B2 (ja) * | 1999-09-24 | 2005-06-29 | 株式会社東芝 | センサデバイス |
| US20040096895A1 (en) * | 2001-01-18 | 2004-05-20 | Lakey Jeremy Hugh | Biosensor with covalently attached membrane-spanning proteins |
| AU2003245272A1 (en) | 2002-05-10 | 2003-11-11 | The Texas A And M University System | Stochastic sensing through covalent interactions |
| JP4394916B2 (ja) * | 2003-09-19 | 2010-01-06 | 独立行政法人科学技術振興機構 | 人工脂質二重膜の形成装置および人工脂質二重膜の形成方法、並びにその利用 |
| EP1712909B1 (en) * | 2004-01-21 | 2012-09-19 | Japan Science and Technology Agency | Method of forming planar lipid double membrane for membrane protein analysis and apparatus therefor |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8627531B2 (en) | 2001-09-04 | 2014-01-14 | Sharp Kabushiki Kaisha | Vacuum cleaner and device having ion generator |
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| GB0505971D0 (en) | 2005-04-27 |
| WO2006100484A2 (en) | 2006-09-28 |
| US7939270B2 (en) | 2011-05-10 |
| JP2008537106A (ja) | 2008-09-11 |
| WO2006100484A3 (en) | 2008-05-29 |
| EP1861071B1 (en) | 2010-07-07 |
| DE602006015292D1 (de) | 2010-08-19 |
| ATE473438T1 (de) | 2010-07-15 |
| US20080153150A1 (en) | 2008-06-26 |
| EP1861071A2 (en) | 2007-12-05 |
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