DE602006015292D1 - Zuführung von molekülen an eine lipiddoppelschicht - Google Patents

Zuführung von molekülen an eine lipiddoppelschicht

Info

Publication number
DE602006015292D1
DE602006015292D1 DE602006015292T DE602006015292T DE602006015292D1 DE 602006015292 D1 DE602006015292 D1 DE 602006015292D1 DE 602006015292 T DE602006015292 T DE 602006015292T DE 602006015292 T DE602006015292 T DE 602006015292T DE 602006015292 D1 DE602006015292 D1 DE 602006015292D1
Authority
DE
Germany
Prior art keywords
molecule
molecules
introduction
double layer
carrier surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006015292T
Other languages
English (en)
Inventor
John Hagan Pryce Bayley
Matthew Alexander Holden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Original Assignee
Oxford University Innovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford University Innovation Ltd filed Critical Oxford University Innovation Ltd
Publication of DE602006015292D1 publication Critical patent/DE602006015292D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Sustainable Development (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE602006015292T 2005-03-23 2006-03-22 Zuführung von molekülen an eine lipiddoppelschicht Active DE602006015292D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0505971.2A GB0505971D0 (en) 2005-03-23 2005-03-23 Delivery of molecules to a lipid bilayer
PCT/GB2006/001057 WO2006100484A2 (en) 2005-03-23 2006-03-22 Deliver of molecules to a li id bila

Publications (1)

Publication Number Publication Date
DE602006015292D1 true DE602006015292D1 (de) 2010-08-19

Family

ID=34531741

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006015292T Active DE602006015292D1 (de) 2005-03-23 2006-03-22 Zuführung von molekülen an eine lipiddoppelschicht

Country Status (7)

Country Link
US (1) US7939270B2 (de)
EP (1) EP1861071B1 (de)
JP (1) JP5253148B2 (de)
AT (1) ATE473438T1 (de)
DE (1) DE602006015292D1 (de)
GB (1) GB0505971D0 (de)
WO (1) WO2006100484A2 (de)

Families Citing this family (149)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4159298B2 (ja) 2001-09-04 2008-10-01 シャープ株式会社 電気掃除機及び機器
US9233846B2 (en) 2005-10-14 2016-01-12 The Regents Of The University Of California Formation and encapsulation of molecular bilayer and monolayer membranes
GB0523282D0 (en) 2005-11-15 2005-12-21 Isis Innovation Methods using pores
US9415422B2 (en) 2006-03-10 2016-08-16 Siemens Industry, Inc. Mail sorting system
CN101495656B (zh) * 2006-06-07 2017-02-08 纽约哥伦比亚大学理事会 采用带修饰的核苷酸通过纳米通道进行dna序列测定
GB2447043A (en) * 2007-02-20 2008-09-03 Oxford Nanolabs Ltd Lipid bilayer sensor system
US20110121840A1 (en) * 2007-02-20 2011-05-26 Gurdial Singh Sanghera Lipid Bilayer Sensor System
GB2446823A (en) * 2007-02-20 2008-08-27 Oxford Nanolabs Ltd Formulation of lipid bilayers
US8500982B2 (en) 2007-04-04 2013-08-06 The Regents Of The University Of California Compositions, devices, systems, and methods for using a nanopore
GB0716264D0 (en) 2007-08-21 2007-09-26 Isis Innovation Bilayers
GB2453377A (en) 2007-10-05 2009-04-08 Isis Innovation Transmembrane protein pores and molecular adapters therefore.
US8124191B2 (en) 2007-11-30 2012-02-28 Electronic Bio Sciences, Llc Method and apparatus for single side bilayer formation
GB0724736D0 (en) 2007-12-19 2008-01-30 Oxford Nanolabs Ltd Formation of layers of amphiphilic molecules
WO2009143425A1 (en) * 2008-05-22 2009-11-26 The Regents Of The University Of California Membrane precursors and membranes formed therefrom
WO2010004265A1 (en) 2008-07-07 2010-01-14 Oxford Nanopore Technologies Limited Enzyme-pore constructs
GB0820927D0 (en) 2008-11-14 2008-12-24 Isis Innovation Method
WO2010086602A1 (en) 2009-01-30 2010-08-05 Oxford Nanopore Technologies Limited Hybridization linkers
KR101797773B1 (ko) 2009-01-30 2017-11-15 옥스포드 나노포어 테크놀로지즈 리미티드 막횡단 시퀀싱에서 핵산 구축물용 어댑터
GB0905140D0 (en) 2009-03-25 2009-05-06 Isis Innovation Method
US9678055B2 (en) 2010-02-08 2017-06-13 Genia Technologies, Inc. Methods for forming a nanopore in a lipid bilayer
US8324914B2 (en) 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
US9605307B2 (en) 2010-02-08 2017-03-28 Genia Technologies, Inc. Systems and methods for forming a nanopore in a lipid bilayer
EP2614156B1 (de) 2010-09-07 2018-08-01 The Regents of The University of California Bis auf ein nukleotid genaue steuerung der dna-bewegung in einer nanopore mithilfe eines prozessiven enzyms
ES2641871T3 (es) 2010-12-17 2017-11-14 The Trustees Of Columbia University In The City Of New York Secuenciación de ADN mediante síntesis usando nucleótidos modificados y detección con nanoporos
US9121059B2 (en) 2010-12-22 2015-09-01 Genia Technologies, Inc. Nanopore-based single molecule characterization
GB201100516D0 (en) 2011-01-12 2011-02-23 Isis Innovation Method using fluorinated amphiphiles
US8962242B2 (en) 2011-01-24 2015-02-24 Genia Technologies, Inc. System for detecting electrical properties of a molecular complex
US9110478B2 (en) 2011-01-27 2015-08-18 Genia Technologies, Inc. Temperature regulation of measurement arrays
US9751915B2 (en) 2011-02-11 2017-09-05 Oxford Nanopore Technologies Ltd. Mutant pores
US8968539B2 (en) 2011-03-08 2015-03-03 Electronic Biosciences, Inc. Methods for voltage-induced protein incorporation into planar lipid bilayers
KR101963918B1 (ko) 2011-05-27 2019-03-29 옥스포드 나노포어 테크놀로지즈 리미티드 커플링 방법
JP6298404B2 (ja) 2011-07-25 2018-03-20 オックスフォード ナノポール テクノロジーズ リミテッド 膜貫通ポアを用いる二重鎖ポリヌクレオチド配列決定のためのヘアピンループ方法
US9150598B2 (en) * 2011-10-05 2015-10-06 The Regents Of The University Of California Masking apertures enabling automation and solution exchange in sessile bilayers
CN104039979B (zh) 2011-10-21 2016-08-24 牛津纳米孔技术公司 使用孔和Hel308解旋酶表征目标多核苷酸的酶方法
GB201119032D0 (en) 2011-11-03 2011-12-14 Isis Innovation Multisomes: encapsulated droplet networks
WO2013098561A1 (en) 2011-12-29 2013-07-04 Oxford Nanopore Technologies Limited Method for characterising a polynucelotide by using a xpd helicase
KR102086182B1 (ko) 2011-12-29 2020-03-06 옥스포드 나노포어 테크놀로지즈 리미티드 효소 방법
GB201202519D0 (en) 2012-02-13 2012-03-28 Oxford Nanopore Tech Ltd Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules
WO2013121201A1 (en) 2012-02-15 2013-08-22 Oxford Nanopore Technologies Limited Aptamer method
EP3736339B1 (de) 2012-02-16 2022-07-27 Oxford Nanopore Technologies plc Analyse von messungen eines polymers
US8986629B2 (en) 2012-02-27 2015-03-24 Genia Technologies, Inc. Sensor circuit for controlling, detecting, and measuring a molecular complex
ES2906186T3 (es) 2012-04-09 2022-04-13 Univ Columbia Método para la preparación de nanoporo y usos del mismo
AU2013246702B2 (en) 2012-04-10 2017-06-15 Oxford Nanopore Technologies Limited Mutant lysenin pores
WO2013188841A1 (en) 2012-06-15 2013-12-19 Genia Technologies, Inc. Chip set-up and high-accuracy nucleic acid sequencing
ES2779699T3 (es) 2012-06-20 2020-08-18 Univ Columbia Secuenciación de ácidos nucleicos mediante detección en nanoporos de moléculas de etiqueta
US9797009B2 (en) 2012-07-19 2017-10-24 Oxford Nanopore Technologies Limited Enzyme construct
BR112015001054A8 (pt) 2012-07-19 2022-08-02 Oxford Nanopore Tech Ltd Helicase monomérica que é membro da superfamília 1 ou superfamília 2, helicase hel308 isolada, método para caracterizar um polinucleotídeo alvo, e, sensor para a caracterização de um polinucleotídeo alvo
WO2014013259A1 (en) 2012-07-19 2014-01-23 Oxford Nanopore Technologies Limited Ssb method
US9551023B2 (en) 2012-09-14 2017-01-24 Oxford Nanopore Technologies Ltd. Sample preparation method
GB201219201D0 (en) 2012-10-25 2012-12-12 Isis Innovation Hydrogel network
GB201219196D0 (en) 2012-10-25 2012-12-12 Isis Innovation Droplet assembly method
GB201313121D0 (en) 2013-07-23 2013-09-04 Oxford Nanopore Tech Ltd Array of volumes of polar medium
JP6375301B2 (ja) 2012-10-26 2018-08-15 オックスフォード ナノポール テクノロジーズ リミテッド 液滴界面
US9995728B2 (en) 2012-11-06 2018-06-12 Oxford Nanopore Technologies Ltd. Quadruplex method
US9605309B2 (en) 2012-11-09 2017-03-28 Genia Technologies, Inc. Nucleic acid sequencing using tags
US11213797B2 (en) * 2012-12-07 2022-01-04 Oxford University Innovation Limited Droplet assembly by 3D printing
GB201222928D0 (en) 2012-12-19 2013-01-30 Oxford Nanopore Tech Ltd Analysis of a polynucleotide
EP2746772B1 (de) 2012-12-20 2016-03-23 AIT Austrian Institute of Technology GmbH Lipidmembran-umhüllte Partikel mit Membranproteinen
US9759711B2 (en) 2013-02-05 2017-09-12 Genia Technologies, Inc. Nanopore arrays
GB201314695D0 (en) 2013-08-16 2013-10-02 Oxford Nanopore Tech Ltd Method
EP2964779B1 (de) 2013-03-08 2018-08-29 Oxford Nanopore Technologies Limited Verwendung von spacer-elementen in einer nukleinsäure zur kontrolle der bewegung einer helicase
GB201318465D0 (en) 2013-10-18 2013-12-04 Oxford Nanopore Tech Ltd Method
EP2971051A4 (de) 2013-03-15 2017-03-01 The Trustees of Columbia University in the City of New York Verfahren zur erkennung mehrerer vordefinierter verbindungen in einer probe
GB201313477D0 (en) 2013-07-29 2013-09-11 Univ Leuven Kath Nanopore biosensors for detection of proteins and nucleic acids
GB201316849D0 (en) 2013-09-23 2013-11-06 Isis Innovation Method
US9551697B2 (en) 2013-10-17 2017-01-24 Genia Technologies, Inc. Non-faradaic, capacitively coupled measurement in a nanopore cell array
AU2014335915B2 (en) 2013-10-18 2020-12-17 Oxford Nanopore Technologies Limited Modified helicases
GB201406151D0 (en) 2014-04-04 2014-05-21 Oxford Nanopore Tech Ltd Method
US9322062B2 (en) 2013-10-23 2016-04-26 Genia Technologies, Inc. Process for biosensor well formation
CA2926138A1 (en) 2013-10-23 2015-04-30 Genia Technologies, Inc. High speed molecular sensing with nanopores
CN113528632A (zh) 2013-11-26 2021-10-22 伊鲁米那股份有限公司 用于多核苷酸测序的组合物和方法
EP2886663A1 (de) 2013-12-19 2015-06-24 Centre National de la Recherche Scientifique (CNRS) Nanoporensequenzierung mit replikativen Polymerasen und Helicasen
AU2015208919B9 (en) 2014-01-22 2021-04-01 Oxford Nanopore Technologies Limited Method for attaching one or more polynucleotide binding proteins to a target polynucleotide
GB201406155D0 (en) 2014-04-04 2014-05-21 Oxford Nanopore Tech Ltd Method
GB201403096D0 (en) 2014-02-21 2014-04-09 Oxford Nanopore Tech Ltd Sample preparation method
EP3122759B1 (de) 2014-03-24 2022-06-01 The Trustees of Columbia University in the City of New York Chemische verfahren zur herstellung von markierten nukleotiden
WO2015150786A1 (en) 2014-04-04 2015-10-08 Oxford Nanopore Technologies Limited Method for characterising a double stranded nucleic acid using a nano-pore and anchor molecules at both ends of said nucleic acid
GB201417712D0 (en) 2014-10-07 2014-11-19 Oxford Nanopore Tech Ltd Method
CN106459159B (zh) 2014-05-02 2021-11-30 牛津纳米孔技术公司 突变孔
ES2912963T3 (es) 2014-07-31 2022-05-30 Illumina Inc Sensores híbridos de nanoporo
EP3224274B1 (de) 2014-09-01 2024-02-14 Vib Vzw Mutante csgg poren
EP3204511B1 (de) 2014-10-07 2021-07-28 Oxford Nanopore Technologies Limited Mutante poren
GB201418159D0 (en) 2014-10-14 2014-11-26 Oxford Nanopore Tech Ltd Method
EP3971300B1 (de) 2014-10-16 2024-06-05 Oxford Nanopore Technologies plc Sortierung von polymeren
GB201418469D0 (en) 2014-10-17 2014-12-03 Oxford Nanopore Tech Ltd Method
GB201418512D0 (en) 2014-10-17 2014-12-03 Oxford Nanopore Tech Ltd Electrical device with detachable components
CN107438618A (zh) 2015-01-26 2017-12-05 塞勒克提斯公司 赋予结合至cd123的嵌合抗原受体用于治疗复发性/难治性急性骨髓性淋巴瘤或母细胞性浆细胞样树突状细胞肿瘤的t细胞受体敲除的工程化免疫细胞
GB201502809D0 (en) 2015-02-19 2015-04-08 Oxford Nanopore Tech Ltd Mutant pore
GB201502810D0 (en) 2015-02-19 2015-04-08 Oxford Nanopore Tech Ltd Method
CN107735686B (zh) 2015-04-14 2021-06-11 鲁汶天主教大学 具有内部蛋白质衔接子的纳米孔
CA3011830A1 (en) 2015-12-08 2017-06-15 Katholieke Universiteit Leuven Ku Leuven Research & Development Modified nanopores, compositions comprising the same, and uses thereof
CN108884150A (zh) 2016-03-02 2018-11-23 牛津纳米孔技术公司 突变孔
WO2017174990A1 (en) 2016-04-06 2017-10-12 Oxford Nanopore Technologies Limited Mutant pore
EP4063521B1 (de) 2016-05-25 2024-02-21 Oxford Nanopore Technologies PLC Verfahren zur nanopor-sequenzierung
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
GB201609221D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
GB201611770D0 (en) 2016-07-06 2016-08-17 Oxford Nanopore Tech Microfluidic device
GB201616590D0 (en) 2016-09-29 2016-11-16 Oxford Nanopore Technologies Limited Method
JP2018059786A (ja) * 2016-10-04 2018-04-12 住友化学株式会社 嗅覚受容体複合体を用いた標的物質の検出装置及び検出方法並びに該検出装置の製造方法
GB201617886D0 (en) 2016-10-21 2016-12-07 Oxford Nanopore Technologies Limited Method
GB201620450D0 (en) 2016-12-01 2017-01-18 Oxford Nanopore Tech Ltd Method
CN110267974A (zh) 2017-02-10 2019-09-20 牛津纳米孔技术公司 修饰的纳米孔、包含其的组合物及其用途
GB201707140D0 (en) 2017-05-04 2017-06-21 Oxford Nanopore Tech Ltd Method
GB201707122D0 (en) 2017-05-04 2017-06-21 Oxford Nanopore Tech Ltd Pore
CA3066715A1 (en) 2017-06-30 2019-01-03 Vib Vzw Novel protein pores
CN111225744B (zh) * 2017-10-23 2022-05-03 豪夫迈·罗氏有限公司 使用渗透不平衡除去和重新插入膜中的蛋白纳米孔
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method
GB201808556D0 (en) 2018-05-24 2018-07-11 Oxford Nanopore Tech Ltd Method
GB201809323D0 (en) 2018-06-06 2018-07-25 Oxford Nanopore Tech Ltd Method
GB201811623D0 (en) 2018-07-16 2018-08-29 Univ Oxford Innovation Ltd Molecular hopper
US20220162692A1 (en) 2018-07-30 2022-05-26 Oxford University Innovation Limited Assemblies
GB201818216D0 (en) 2018-11-08 2018-12-26 Oxford Nanopore Tech Ltd Pore
EP3877547A1 (de) 2018-11-08 2021-09-15 Oxford Nanopore Technologies Limited Pore
GB201821155D0 (en) 2018-12-21 2019-02-06 Oxford Nanopore Tech Ltd Method
CN113574381A (zh) 2019-03-12 2021-10-29 牛津纳米孔科技公司 纳米孔感测装置、组件和操作方法
GB2580988B (en) 2019-03-19 2022-04-13 Oxford Nanopore Tech Ltd Current measurement apparatus, molecular entity sensing apparatus, method of measuring a current, method of sensing a molecular entity
US20220162568A1 (en) 2019-04-09 2022-05-26 Oxford Nanopore Technologies Limited Pore
GB201907246D0 (en) 2019-05-22 2019-07-03 Oxford Nanopore Tech Ltd Method
GB201907244D0 (en) 2019-05-22 2019-07-03 Oxford Nanopore Tech Ltd Method
GB201913997D0 (en) 2019-09-27 2019-11-13 Oxford Nanopore Tech Ltd Method
GB201915480D0 (en) 2019-10-25 2019-12-11 Oxford Nanopore Tech Ltd Improved nanopore sensing device, components and method of manufacture
GB201917060D0 (en) 2019-11-22 2020-01-08 Oxford Nanopore Tech Ltd Method
EP4070092B1 (de) 2019-12-02 2023-08-30 Oxford Nanopore Technologies PLC Verfahren zur charakterisierung eines zielpolypeptids unter verwendung einer nanopore
GB201917742D0 (en) 2019-12-04 2020-01-15 Oxford Nanopore Tech Ltd Method
GB202004944D0 (en) 2020-04-03 2020-05-20 King S College London Method
GB202016874D0 (en) 2020-10-23 2020-12-09 Oxford Nanopore Tech Ltd Nanopore support structure and manufacture thereof
GB202009349D0 (en) 2020-06-18 2020-08-05 Oxford Nanopore Tech Ltd Method
AU2021291140A1 (en) 2020-06-18 2023-02-02 Oxford Nanopore Technologies Limited Method of characterising a polynucleotide moving through a nanopore
WO2021255475A1 (en) 2020-06-18 2021-12-23 Oxford Nanopore Technologies Limited A method of selectively characterising a polynucleotide using a detector
KR20230038566A (ko) 2020-07-17 2023-03-20 옥스포드 나노포어 테크놀로지즈 피엘씨 나노포어 감지 디바이스
GB202015993D0 (en) 2020-10-08 2020-11-25 Oxford Nanopore Tech Ltd Method
WO2022243692A1 (en) 2021-05-19 2022-11-24 Oxford Nanopore Technologies Plc Methods for complement strand sequencing
GB202107192D0 (en) 2021-05-19 2021-06-30 Oxford Nanopore Tech Ltd Method
GB202107354D0 (en) 2021-05-24 2021-07-07 Oxford Nanopore Tech Ltd Method
GB202112235D0 (en) 2021-08-26 2021-10-13 Oxford Nanopore Tech Ltd Nanopore
GB202118908D0 (en) 2021-12-23 2022-02-09 Oxford Nanopore Tech Ltd Method
GB202118939D0 (en) 2021-12-23 2022-02-09 Oxford Nanopore Tech Plc Pore
GB202118906D0 (en) 2021-12-23 2022-02-09 Oxford Nanopore Tech Ltd Method
GB202204919D0 (en) 2022-04-04 2022-05-18 Oxford Nanopore Tech Plc Method
GB202205617D0 (en) 2022-04-14 2022-06-01 Oxford Nanopore Tech Plc Novel modified protein pores and enzymes
WO2023222657A1 (en) 2022-05-17 2023-11-23 Oxford Nanopore Technologies Plc Method and adaptors
GB202211607D0 (en) 2022-08-09 2022-09-21 Oxford Nanopore Tech Plc Novel pore monomers and pores
GB202211602D0 (en) 2022-08-09 2022-09-21 Oxford Nanopore Tech Plc Novel pore monomers and pores
WO2024033443A1 (en) 2022-08-09 2024-02-15 Oxford Nanopore Technologies Plc Novel pore monomers and pores
WO2024033447A1 (en) 2022-08-09 2024-02-15 Oxford Nanopore Technologies Plc De novo pores
WO2024089270A2 (en) 2022-10-28 2024-05-02 Oxford Nanopore Technologies Plc Pore monomers and pores
GB202216162D0 (en) 2022-10-31 2022-12-14 Oxford Nanopore Tech Plc Method
GB202216905D0 (en) 2022-11-11 2022-12-28 Oxford Nanopore Tech Plc Novel pore monomers and pores
GB202307486D0 (en) 2023-05-18 2023-07-05 Oxford Nanopore Tech Plc Method

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3799743A (en) 1971-11-22 1974-03-26 Alexander James Stable lysis responsive lipid bilayer
US6327410B1 (en) * 1997-03-14 2001-12-04 The Trustees Of Tufts College Target analyte sensors utilizing Microspheres
GB9712386D0 (en) * 1997-06-14 1997-08-13 Univ Coventry Biosensor
AU2536299A (en) * 1998-02-17 1999-08-30 University Of Wales College Of Medicine Method and apparatus for introducing substances into the cell plasma membrane and/or cytosol
AU763092B2 (en) * 1998-08-31 2003-07-10 Gryphon Sciences Lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides
JP3665720B2 (ja) * 1999-09-24 2005-06-29 株式会社東芝 センサデバイス
DE60213948T2 (de) * 2001-01-18 2007-03-08 Newcastle University Ventures Ltd. Biosensor mit kovalent gebundenen membranüberspannenden proteinen
WO2003095669A1 (en) 2002-05-10 2003-11-20 The Texas A & M University System Stochastic sensing through covalent interactions
JP4394916B2 (ja) * 2003-09-19 2010-01-06 独立行政法人科学技術振興機構 人工脂質二重膜の形成装置および人工脂質二重膜の形成方法、並びにその利用
WO2005071405A1 (ja) * 2004-01-21 2005-08-04 Japan Science And Technology Agency 膜タンパク質分析用平面脂質二重膜の形成方法とその装置

Also Published As

Publication number Publication date
US7939270B2 (en) 2011-05-10
JP5253148B2 (ja) 2013-07-31
EP1861071A2 (de) 2007-12-05
EP1861071B1 (de) 2010-07-07
ATE473438T1 (de) 2010-07-15
WO2006100484A2 (en) 2006-09-28
GB0505971D0 (en) 2005-04-27
JP2008537106A (ja) 2008-09-11
US20080153150A1 (en) 2008-06-26
WO2006100484A3 (en) 2008-05-29

Similar Documents

Publication Publication Date Title
DE602006015292D1 (de) Zuführung von molekülen an eine lipiddoppelschicht
BRPI0512396A (pt) polipeptìdeos biossintéticos utilizando aminoácidos codificados não naturalmente
BRPI0816426A2 (pt) Dispositivo para investigar uma molécula, método para investigar uma molécula, substrato adequado para uso no dispositivo para investigar moléculas, método para sequenciar um ácido nucléico.
BRPI0409911A (pt) método para liberar uma molécula em uma célula, e, complexo carreador
WO2008121375A3 (en) Modified surfaces for immobilization of active molecules
WO2006076703A3 (en) Porous biosensing device
WO2010039247A3 (en) Substrates with surfaces modified with peg
WO2007001436A3 (en) Surface modification for non-specific adsorption of biological material
WO2008039769A3 (en) Methods and devices for analyzing small rna molecules
CL2011000919A1 (es) Compuestos derivados de n-fenil-4-oxo-(1,4-dihidroquinolin o 1h-quinolin)-3-carboxamida, moduladores del regulador de conductancia transmembrana de fibrosis quistica (cftr); compuestos intermediarios; composicion farmaceutica; kit farmaceutico; proceso de preparacion; y uso para el tratamiento de fibrosis quistica, diabetes, entre otros.
EA200800160A1 (ru) Композиты восстановленной ионной жидкостью целлюлозы в качестве матриц твёрдых подложек
DK2002019T3 (da) Artikel med derpå anbragte lokaliserede molekyler samt fremgangsmåde til fremstilling deraf
AU2013207599A1 (en) Process for determining one or more analytes in samples of biological origin having complex composition, and use thereof
ATE458824T1 (de) Zellfreie in-vitro-transkription und translation von membranproteinen in gebundene planare lipidschichten
DE60232468D1 (de) Ente und damit zusammenhängende verfahren
CY1110860T1 (el) Αναστροφη μεταγραφαση τελομερασης πτηνου
EP2628746A3 (de) Verfahren zur Konzentration eines Polypeptids
WO2009121034A3 (en) Multicapillary sample preparation devices and methods for processing analytes
WO2006135793A3 (en) Protein engineering with analogous contact environments
WO2007062174A3 (en) Devices and methods for high-pressure refolding of proteins
WO2006079057A3 (en) Methods and compositions for specific inhibition of protein splicing by small molecules
WO2008093828A1 (ja) 生細胞表層分子解析方法及び部材
DE602006014089D1 (de) Probeninjektor, probeninjektionsverfahren und vorrichtung zur flüssigkeitschromatographie
DE602006010187D1 (de) Einzelsequenzhybridisierungssonden
WO2011145126A3 (en) A method for the preparation of conjugates based on transglutaminase