DE60232468D1 - Ente und damit zusammenhängende verfahren - Google Patents

Ente und damit zusammenhängende verfahren

Info

Publication number
DE60232468D1
DE60232468D1 DE60232468T DE60232468T DE60232468D1 DE 60232468 D1 DE60232468 D1 DE 60232468D1 DE 60232468 T DE60232468 T DE 60232468T DE 60232468 T DE60232468 T DE 60232468T DE 60232468 D1 DE60232468 D1 DE 60232468D1
Authority
DE
Germany
Prior art keywords
separation
duck
associated methods
channel
porous matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60232468T
Other languages
English (en)
Inventor
Richard N Zare
Maria T Dulay
Joselito P Quirino
Bryson D Bennett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
R UNIVERSITY
Original Assignee
R UNIVERSITY
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/124,654 external-priority patent/US6875348B2/en
Application filed by R UNIVERSITY filed Critical R UNIVERSITY
Application granted granted Critical
Publication of DE60232468D1 publication Critical patent/DE60232468D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206Organic carriers, supports or substrates
    • B01J20/3208Polymeric carriers, supports or substrates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244Non-macromolecular compounds
    • B01J20/3246Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3257Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such
    • B01J20/3259Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such comprising at least two different types of heteroatoms selected from nitrogen, oxygen or sulfur with at least one silicon atom
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54Sorbents specially adapted for analytical or investigative chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/80Aspects related to sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J2220/86Sorbents applied to inner surfaces of columns or capillaries
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/52Physical parameters
    • G01N2030/524Physical parameters structural properties
    • G01N2030/528Monolithic sorbent material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Folding Of Thin Sheet-Like Materials, Special Discharging Devices, And Others (AREA)
  • Catching Or Destruction (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Colloid Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE60232468T 2001-08-13 2002-08-13 Ente und damit zusammenhängende verfahren Expired - Fee Related DE60232468D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/929,275 US6866785B2 (en) 2001-08-13 2001-08-13 Photopolymerized sol-gel column and associated methods
US10/124,654 US6875348B2 (en) 2000-02-18 2002-04-16 Separation column having a photopolymerized sol-gel component and associated methods
PCT/US2002/025757 WO2003016859A2 (en) 2001-08-13 2002-08-13 Separation column having a photopolymerized sol-gel component and associated methods

Publications (1)

Publication Number Publication Date
DE60232468D1 true DE60232468D1 (de) 2009-07-09

Family

ID=25457591

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60236165T Expired - Lifetime DE60236165D1 (de) 2001-08-13 2002-08-13 Photopolymerisierte sol-gel-säule mit gebundener phase und zugehörige verfahren
DE60232468T Expired - Fee Related DE60232468D1 (de) 2001-08-13 2002-08-13 Ente und damit zusammenhängende verfahren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60236165T Expired - Lifetime DE60236165D1 (de) 2001-08-13 2002-08-13 Photopolymerisierte sol-gel-säule mit gebundener phase und zugehörige verfahren

Country Status (5)

Country Link
US (2) US6866785B2 (de)
AT (2) ATE465795T1 (de)
AU (1) AU2002326633A1 (de)
DE (2) DE60236165D1 (de)
ES (1) ES2345328T3 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6833242B2 (en) * 1997-09-23 2004-12-21 California Institute Of Technology Methods for detecting and sorting polynucleotides based on size
AU2001273057A1 (en) * 2000-06-27 2002-01-08 Fluidigm Corporation A microfluidic design automation method and system
EP2299256A3 (de) 2000-09-15 2012-10-10 California Institute Of Technology Miniaturisierte Querstromvorrichtungen und -Verfahren
WO2002065005A1 (en) * 2000-11-06 2002-08-22 California Institute Of Technology Electrostatic valves for microfluidic devices
EP1384022A4 (de) 2001-04-06 2004-08-04 California Inst Of Techn Nukleinsäure-amplifikation verwendende mikrofluidvorrichtungen
US7075162B2 (en) * 2001-08-30 2006-07-11 Fluidigm Corporation Electrostatic/electrostrictive actuation of elastomer structures using compliant electrodes
US7192629B2 (en) * 2001-10-11 2007-03-20 California Institute Of Technology Devices utilizing self-assembled gel and method of manufacture
US8440093B1 (en) 2001-10-26 2013-05-14 Fuidigm Corporation Methods and devices for electronic and magnetic sensing of the contents of microfluidic flow channels
US7691333B2 (en) * 2001-11-30 2010-04-06 Fluidigm Corporation Microfluidic device and methods of using same
WO2003048295A1 (en) 2001-11-30 2003-06-12 Fluidigm Corporation Microfluidic device and methods of using same
US20030164297A1 (en) * 2002-03-04 2003-09-04 Corning Incorporated Electrophoretic inorganic porous material
WO2003085379A2 (en) * 2002-04-01 2003-10-16 Fluidigm Corporation Microfluidic particle-analysis systems
US7312085B2 (en) * 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
WO2004000721A2 (en) * 2002-06-24 2003-12-31 Fluidigm Corporation Recirculating fluidic network and methods for using the same
US7473367B2 (en) * 2002-06-26 2009-01-06 Dionex Corporation Monolithic column
US6749749B2 (en) * 2002-06-26 2004-06-15 Isco, Inc. Separation system, components of a separation system and methods of making and using them
US20050061745A1 (en) * 2002-06-26 2005-03-24 Teledyne Isco, Inc. Separation system, components of a separation system and methods of making and using them
CA2500283A1 (en) 2002-09-25 2004-04-08 California Institute Of Technology Microfluidic large scale integration
WO2004040001A2 (en) 2002-10-02 2004-05-13 California Institute Of Technology Microfluidic nucleic acid analysis
GB0227424D0 (en) * 2002-11-25 2002-12-31 Univ Warwick Coatings
CA2521171C (en) * 2003-04-03 2013-05-28 Fluidigm Corp. Microfluidic devices and methods of using same
US7476363B2 (en) * 2003-04-03 2009-01-13 Fluidigm Corporation Microfluidic devices and methods of using same
US8828663B2 (en) * 2005-03-18 2014-09-09 Fluidigm Corporation Thermal reaction device and method for using the same
US7604965B2 (en) 2003-04-03 2009-10-20 Fluidigm Corporation Thermal reaction device and method for using the same
US20050145496A1 (en) 2003-04-03 2005-07-07 Federico Goodsaid Thermal reaction device and method for using the same
WO2004105910A2 (en) * 2003-05-28 2004-12-09 Waters Investments Limited Novel nanocomposites and their application as monolith columns
US7413712B2 (en) * 2003-08-11 2008-08-19 California Institute Of Technology Microfluidic rotary flow reactor matrix
US20050127002A1 (en) * 2003-12-12 2005-06-16 Zare Richard N. Immobilized-enzyme microreactor devices for characterization of biomolecular analytes and associated methods
CA2599591C (en) 2005-02-28 2013-01-08 University Of Virginia Patent Foundation Dna extraction using a photo-polymerized monolith in a capillary
US20070181479A1 (en) * 2005-11-21 2007-08-09 Pentax Corporation Column and method of manufacturing the column
WO2007114144A1 (ja) * 2006-03-29 2007-10-11 Daiso Co., Ltd. 修飾シリカゲル及びその利用
EP2105736A1 (de) * 2008-03-28 2009-09-30 Novartis Ag DNA-Analyse mittels Kapillar-Elektrophorese
WO2009126207A1 (en) * 2008-04-08 2009-10-15 Waters Technologies Corporation Composite materials containing nanoparticles and their use in chromatography
WO2009132330A2 (en) * 2008-04-25 2009-10-29 Biotrove, Inc. Separation cartridges and methods for fabrication and use thereof
US9129785B2 (en) 2013-08-01 2015-09-08 The Board Of Trustees Of The Leland Stanford Junior University Metal organic polymer matrices and systems for chemical and biochemical mass spectrometry and methods of use thereof
US20170184543A1 (en) * 2014-04-15 2017-06-29 University Of Washington Isotachophoretic device and methods
CN112337411B (zh) * 2020-10-13 2023-05-23 烟台大学 一种金属有机凝胶的制备方法及其应用

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3503712A (en) 1966-05-18 1970-03-31 Research Corp Apparatus for effecting interactions of fluids at extended solid surfaces
US3568840A (en) 1967-12-30 1971-03-09 Mitsubishi Chem Ind Packing materials for gel permeation chromatography
US3757490A (en) 1971-06-07 1973-09-11 Ja Ma Chromatographic adsorbents
US3808125A (en) 1972-08-25 1974-04-30 Phillips Petroleum Co Chromatographic apparatus
US3878092A (en) 1973-03-12 1975-04-15 Phillips Petroleum Co Chromatographic colums
US4293415A (en) 1979-04-27 1981-10-06 Hewlett-Packard Company Silica chromatographic column
US4323439A (en) 1979-12-31 1982-04-06 The Regents Of The University Of California Method and apparatus for dynamic equilibrium electrophoresis
US4790919A (en) 1984-06-28 1988-12-13 E. I. Du Pont De Nemours And Company Process for preparation of electrophoresis gel material
US4617102A (en) 1985-03-21 1986-10-14 Lifecodes Corp. Process and apparatus for purifying and concentrating DNA from crude mixtures containing DNA
US4675300A (en) 1985-09-18 1987-06-23 The Board Of Trustees Of The Leland Stanford Junior University Laser-excitation fluorescence detection electrokinetic separation
US5116495A (en) 1987-09-11 1992-05-26 Ottosensors Corporation Capillary chromatography device
US5202010A (en) 1987-11-25 1993-04-13 Princeton Biochemicals, Inc. Automated capillary electrophoresis apparatus
IL93134A (en) 1990-01-23 1997-11-20 Yissum Res Dev Co Doped sol-gel glasses for obtaining chemical interactions
US5308495A (en) 1990-01-23 1994-05-03 Yissum, Research Development Company Of The Hebrew University Of Jerusalem Chromatography processes using doped sol gel glasses as chromatographic media
US5200150A (en) * 1990-06-14 1993-04-06 Hewlett-Packard Company Preparation of gel-filled separation columns
US5085756A (en) 1990-08-21 1992-02-04 Hewlett-Packard Company Column separation system for electrophoresis with sample pretreatment
US5135627A (en) 1990-10-15 1992-08-04 Soane Technologies, Inc. Mosaic microcolumns, slabs, and separation media for electrophoresis and chromatography
US5340452A (en) 1991-02-01 1994-08-23 Beckman Instruments, Inc. On-column preconcentration of samples in capillary electrophoresis
US5453382A (en) 1991-08-05 1995-09-26 Indiana University Foundation Electrochromatographic preconcentration method
US5116471A (en) 1991-10-04 1992-05-26 Varian Associates, Inc. System and method for improving sample concentration in capillary electrophoresis
WO1993007945A1 (en) 1991-10-21 1993-04-29 Cornell Research Foundation, Inc. Column with macroporous polymer media
US5552994A (en) * 1992-09-23 1996-09-03 Onkor, Ltd. System for printing social expression cards in response to electronically transmitted orders
US5316680A (en) 1992-10-21 1994-05-31 Cornell Research Foundation, Inc. Multimodal chromatographic separation media and process for using same
US5505831A (en) 1993-01-26 1996-04-09 Bio-Rad Laboratories, Inc. Concentration of biological samples on a microliter scale and analysis by capillary electrophoresis
US5624875A (en) * 1993-07-19 1997-04-29 Merck Patent Gesellschaft Mit Beschrankter Haftung Inorganic porous material and process for making same
US5423966A (en) 1994-01-25 1995-06-13 Perkin-Elmer Corporation On line ion contaminant removal apparatus and method for capillary electrophoresis
US5653875A (en) 1994-02-04 1997-08-05 Supelco, Inc. Nucleophilic bodies bonded to siloxane and use thereof for separations from sample matrices
SE9402091D0 (sv) 1994-06-14 1994-06-14 Pharmacia Biotech Ab Kromatografikolonn
JP3498865B2 (ja) * 1994-09-26 2004-02-23 本田技研工業株式会社 小型雪上車のステップフロア
US5728457A (en) 1994-09-30 1998-03-17 Cornell Research Foundation, Inc. Porous polymeric material with gradients
US5522994A (en) 1995-02-01 1996-06-04 Cornell Research Foundation, Inc. Single column chromatographic determination of small molecules in mixtures with large molecules
WO1996027793A1 (en) 1995-03-03 1996-09-12 Alltech Associates, Inc. Apparatus/method for electrochemically modifying chromatographic material
US5800692A (en) 1995-04-17 1998-09-01 Mayo Foundation For Medical Education And Research Preseparation processor for use in capillary electrophoresis
US5637135A (en) 1995-06-26 1997-06-10 Capillary Technology Corporation Chromatographic stationary phases and adsorbents from hybrid organic-inorganic sol-gels
WO1997017384A1 (en) 1995-11-08 1997-05-15 Kirkpatrick Francis H Methods and reagents for gel electrophoresis
EP0779512B1 (de) 1995-12-14 2001-10-31 Hewlett-Packard Company, A Delaware Corporation Säule für kapillarchromatographische Trennverfahren
US5938919A (en) 1995-12-22 1999-08-17 Phenomenex Fused silica capillary columns protected by flexible shielding
US5667674A (en) 1996-01-11 1997-09-16 Minnesota Mining And Manufacturing Company Adsorption medium and method of preparing same
US5728296A (en) 1996-03-20 1998-03-17 Bio-Rad Laboratories, Inc. Selective recognition of solutes in chromatographic media by artificially created affinity
DE69630109T2 (de) 1996-05-20 2004-04-08 Agilent Technologies, Inc. (n.d.Ges.d.Staates Delaware), Palo Alto Kapillarsäule für chromatographische Trennungen und Verfahren zur Herstellung
US5647979A (en) 1996-06-14 1997-07-15 Bio-Rad Laboratories, Inc. One-step preparation of separation media for reversed-phase chromatography
US5719322A (en) 1996-09-20 1998-02-17 Uop Zeolitic capillary columns for gas chromatography
JP2002505006A (ja) * 1997-06-18 2002-02-12 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 分取クロマトグラフィーによる分離のためのモノリシック吸着剤の使用
US6136187A (en) 1997-12-09 2000-10-24 The Board Of Trustees Of The Leland Stanford Junior University Separation column containing porous matrix and method of packing column
DE69841079D1 (de) * 1998-01-23 2009-10-01 Merck Patent Gmbh Verfahren zur herstellung von inorganischem material in einer kapillare
JPH11287791A (ja) * 1998-04-01 1999-10-19 Naohiro Soga キャピラリーカラム
US6210570B1 (en) * 1998-08-21 2001-04-03 Agilent Technologies, Inc. Monolithic silica column
US6428666B1 (en) 1999-02-22 2002-08-06 Sandia National Laboratories Electrokinetic concentration of charged molecules
JP4843845B2 (ja) * 2000-07-03 2011-12-21 トヨタ自動車株式会社 燃料電池システムおよびその制御方法

Also Published As

Publication number Publication date
DE60236165D1 (de) 2010-06-10
US20030062308A1 (en) 2003-04-03
US6866785B2 (en) 2005-03-15
ATE432117T1 (de) 2009-06-15
US6884346B2 (en) 2005-04-26
ES2345328T3 (es) 2010-09-21
ATE465795T1 (de) 2010-05-15
US20030062309A1 (en) 2003-04-03
AU2002326633A1 (en) 2003-03-03

Similar Documents

Publication Publication Date Title
DE60232468D1 (de) Ente und damit zusammenhängende verfahren
WO2003016859A3 (en) Separation column having a photopolymerized sol-gel component and associated methods
SE0202114D0 (sv) Polymer affinity matrix, a method for the production and use thereof
ATE419629T1 (de) Poröse ferro- oder ferrimagnetische glasteilchen für molekültrennung
ATE342508T1 (de) Kapseln, enthaltend feststoffpartikeln von signalerzeugenden organischen substanzen
WO2007065025A3 (en) Method of dna analysis using micro/nanochannel
ATE405841T1 (de) In-vitro-verfahren zum gleichzeitigen nachweisen und identifizieren von antibiotika unterschiedlicher klassen sowie entsprechender diagnostischer kit
WO2004036189A3 (en) Methods for separating molecules
ATE469911T1 (de) Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung
DE60328001D1 (de) Elektrochemische nachweissystemen
WO2006045103A3 (en) Device and method for removing heavy metals from contaminated samples with membranes comprising purified metallothionein
WO2006008143A3 (en) Apparatus components and methods of using apparatus components to detect the presence of an analyte
DE59912722D1 (de) Kontinuierliches verfahren zur trennung von stoffen nach molekülgrösse
CY1115474T1 (el) Χρωματογραφικη μεθοδος
GB2427374A (en) Compositions and methods for separating enantiomers
DE602004018504D1 (de) Cucurbituril enthaltendes polymer, stationäre phase und säule damit
ATE248631T1 (de) Einstufige vorrichtung und verfahren zur konzentration und säuberung biologischer moleküle
ATE358621T1 (de) Sequenzgestell
EP1265067A4 (de) Säulenpackung für die chromatographie
ES2172801T3 (es) Procedimiento y dispositivo para la purificacion y enriquecimiento de moleculas.
WO2006063041A3 (en) Integrated column, related system and method for liquid chromatography
DE69831429D1 (de) Verfahren zur langzeitlagerung von dns-molekülen, und verpackung zur durchführung dieses verfahrens
DK1476549T3 (da) Fremgangsmåde til konformations-afhængig separering af ikke-cirkulære nukleinsyrer
BRPI0507173A (pt) método para produzir polìmeros de polifenileno substituìdo
ITRM20030502A0 (it) Catalizzatori aerobici per ossidazioni alcoliche in solvente organicoe in anidride carbonica supercritica e processo per la produzione dei

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee