DE602006015292D1 - Zuführung von molekülen an eine lipiddoppelschicht - Google Patents

Zuführung von molekülen an eine lipiddoppelschicht

Info

Publication number
DE602006015292D1
DE602006015292D1 DE602006015292T DE602006015292T DE602006015292D1 DE 602006015292 D1 DE602006015292 D1 DE 602006015292D1 DE 602006015292 T DE602006015292 T DE 602006015292T DE 602006015292 T DE602006015292 T DE 602006015292T DE 602006015292 D1 DE602006015292 D1 DE 602006015292D1
Authority
DE
Germany
Prior art keywords
molecule
molecules
introduction
double layer
carrier surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006015292T
Other languages
German (de)
English (en)
Inventor
John Hagan Pryce Bayley
Matthew Alexander Holden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Original Assignee
Oxford University Innovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford University Innovation Ltd filed Critical Oxford University Innovation Ltd
Publication of DE602006015292D1 publication Critical patent/DE602006015292D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Sustainable Development (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
DE602006015292T 2005-03-23 2006-03-22 Zuführung von molekülen an eine lipiddoppelschicht Active DE602006015292D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0505971.2A GB0505971D0 (en) 2005-03-23 2005-03-23 Delivery of molecules to a lipid bilayer
PCT/GB2006/001057 WO2006100484A2 (en) 2005-03-23 2006-03-22 Deliver of molecules to a li id bila

Publications (1)

Publication Number Publication Date
DE602006015292D1 true DE602006015292D1 (de) 2010-08-19

Family

ID=34531741

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006015292T Active DE602006015292D1 (de) 2005-03-23 2006-03-22 Zuführung von molekülen an eine lipiddoppelschicht

Country Status (7)

Country Link
US (1) US7939270B2 (enExample)
EP (1) EP1861071B1 (enExample)
JP (1) JP5253148B2 (enExample)
AT (1) ATE473438T1 (enExample)
DE (1) DE602006015292D1 (enExample)
GB (1) GB0505971D0 (enExample)
WO (1) WO2006100484A2 (enExample)

Families Citing this family (164)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4159298B2 (ja) 2001-09-04 2008-10-01 シャープ株式会社 電気掃除機及び機器
US9233846B2 (en) 2005-10-14 2016-01-12 The Regents Of The University Of California Formation and encapsulation of molecular bilayer and monolayer membranes
GB0523282D0 (en) 2005-11-15 2005-12-21 Isis Innovation Methods using pores
US9415422B2 (en) 2006-03-10 2016-08-16 Siemens Industry, Inc. Mail sorting system
WO2007146158A1 (en) * 2006-06-07 2007-12-21 The Trustees Of Columbia University In The City Of New York Dna sequencing by nanopore using modified nucleotides
AU2008217578A1 (en) * 2007-02-20 2008-08-28 Oxford Nanopore Technologies Limited Lipid bilayer sensor system
GB2447043A (en) * 2007-02-20 2008-09-03 Oxford Nanolabs Ltd Lipid bilayer sensor system
GB2446823A (en) * 2007-02-20 2008-08-27 Oxford Nanolabs Ltd Formulation of lipid bilayers
US20110005918A1 (en) 2007-04-04 2011-01-13 Akeson Mark A Compositions, devices, systems, and methods for using a nanopore
GB0716264D0 (en) 2007-08-21 2007-09-26 Isis Innovation Bilayers
GB2453377A (en) 2007-10-05 2009-04-08 Isis Innovation Transmembrane protein pores and molecular adapters therefore.
GB2467479B (en) * 2007-11-30 2011-12-28 Electronic Bio Sciences Llc Method and apparatus for single side bilayer formation
GB0724736D0 (en) 2007-12-19 2008-01-30 Oxford Nanolabs Ltd Formation of layers of amphiphilic molecules
WO2009143425A1 (en) * 2008-05-22 2009-11-26 The Regents Of The University Of California Membrane precursors and membranes formed therefrom
EP2307540B1 (en) 2008-07-07 2017-04-19 Oxford Nanopore Technologies Limited Enzyme-pore constructs
GB0820927D0 (en) 2008-11-14 2008-12-24 Isis Innovation Method
KR20110125226A (ko) 2009-01-30 2011-11-18 옥스포드 나노포어 테크놀로지즈 리미티드 혼성화 링커
JP5843614B2 (ja) 2009-01-30 2016-01-13 オックスフォード ナノポア テクノロジーズ リミテッド 膜貫通配列決定における核酸構築物のためのアダプター
GB0905140D0 (en) 2009-03-25 2009-05-06 Isis Innovation Method
US9605307B2 (en) 2010-02-08 2017-03-28 Genia Technologies, Inc. Systems and methods for forming a nanopore in a lipid bilayer
US8324914B2 (en) * 2010-02-08 2012-12-04 Genia Technologies, Inc. Systems and methods for characterizing a molecule
US9678055B2 (en) 2010-02-08 2017-06-13 Genia Technologies, Inc. Methods for forming a nanopore in a lipid bilayer
CN103392008B (zh) 2010-09-07 2017-10-20 加利福尼亚大学董事会 通过持续性酶以一个核苷酸的精度控制dna在纳米孔中的移动
WO2012083249A2 (en) 2010-12-17 2012-06-21 The Trustees Of Columbia University In The City Of New York Dna sequencing by synthesis using modified nucleotides and nanopore detection
US8845880B2 (en) 2010-12-22 2014-09-30 Genia Technologies, Inc. Nanopore-based single DNA molecule characterization, identification and isolation using speed bumps
GB201100516D0 (en) 2011-01-12 2011-02-23 Isis Innovation Method using fluorinated amphiphiles
US8962242B2 (en) 2011-01-24 2015-02-24 Genia Technologies, Inc. System for detecting electrical properties of a molecular complex
US9110478B2 (en) 2011-01-27 2015-08-18 Genia Technologies, Inc. Temperature regulation of measurement arrays
CN103460040B (zh) 2011-02-11 2016-08-17 牛津纳米孔技术有限公司 突变型孔
US8968539B2 (en) 2011-03-08 2015-03-03 Electronic Biosciences, Inc. Methods for voltage-induced protein incorporation into planar lipid bilayers
WO2012164270A1 (en) 2011-05-27 2012-12-06 Oxford Nanopore Technologies Limited Coupling method
IN2014DN00221A (enExample) 2011-07-25 2015-06-05 Oxford Nanopore Tech Ltd
US9150598B2 (en) * 2011-10-05 2015-10-06 The Regents Of The University Of California Masking apertures enabling automation and solution exchange in sessile bilayers
EP2987870B1 (en) 2011-10-21 2020-02-19 Oxford Nanopore Technologies Limited Method of characterizing a target polynucleotide using a transmembrane pore and molecular motor
GB201119032D0 (en) 2011-11-03 2011-12-14 Isis Innovation Multisomes: encapsulated droplet networks
JP6228128B2 (ja) 2011-12-29 2017-11-08 オックスフォード ナノポール テクノロジーズ リミテッド 酵素法
CN104136631B (zh) 2011-12-29 2017-03-01 牛津纳米孔技术公司 使用xpd解旋酶表征多核苷酸的方法
GB201202519D0 (en) 2012-02-13 2012-03-28 Oxford Nanopore Tech Ltd Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules
IN2014DN06796A (enExample) 2012-02-15 2015-05-22 Oxford Nanopore Tech Ltd
WO2013121224A1 (en) 2012-02-16 2013-08-22 Oxford Nanopore Technologies Limited Analysis of measurements of a polymer
US8986629B2 (en) 2012-02-27 2015-03-24 Genia Technologies, Inc. Sensor circuit for controlling, detecting, and measuring a molecular complex
CN107082792A (zh) 2012-04-09 2017-08-22 纽约哥伦比亚大学理事会 纳米孔的制备方法和其用途
KR102083695B1 (ko) 2012-04-10 2020-03-02 옥스포드 나노포어 테크놀로지즈 리미티드 돌연변이체 리세닌 기공
WO2013188841A1 (en) 2012-06-15 2013-12-19 Genia Technologies, Inc. Chip set-up and high-accuracy nucleic acid sequencing
EP3674412A1 (en) 2012-06-20 2020-07-01 The Trustees of Columbia University in the City of New York Nucleic acid sequencing by nanopore detection of tag molecules
WO2014013259A1 (en) 2012-07-19 2014-01-23 Oxford Nanopore Technologies Limited Ssb method
US10808231B2 (en) 2012-07-19 2020-10-20 Oxford Nanopore Technologies Limited Modified helicases
US9797009B2 (en) 2012-07-19 2017-10-24 Oxford Nanopore Technologies Limited Enzyme construct
US9551023B2 (en) 2012-09-14 2017-01-24 Oxford Nanopore Technologies Ltd. Sample preparation method
GB201219196D0 (en) 2012-10-25 2012-12-12 Isis Innovation Droplet assembly method
GB201219201D0 (en) 2012-10-25 2012-12-12 Isis Innovation Hydrogel network
US9823235B2 (en) 2012-10-26 2017-11-21 Oxford Nanopre Technologies Ltd. Droplet interfaces
GB201313121D0 (en) 2013-07-23 2013-09-04 Oxford Nanopore Tech Ltd Array of volumes of polar medium
WO2014072703A1 (en) 2012-11-06 2014-05-15 Oxford Nanopore Technologies Limited Quadruplex method
US9605309B2 (en) 2012-11-09 2017-03-28 Genia Technologies, Inc. Nucleic acid sequencing using tags
US11213797B2 (en) * 2012-12-07 2022-01-04 Oxford University Innovation Limited Droplet assembly by 3D printing
GB201222928D0 (en) 2012-12-19 2013-01-30 Oxford Nanopore Tech Ltd Analysis of a polynucleotide
EP2746772B1 (en) 2012-12-20 2016-03-23 AIT Austrian Institute of Technology GmbH Lipid membrane enveloped particles with membrane proteins
US9759711B2 (en) 2013-02-05 2017-09-12 Genia Technologies, Inc. Nanopore arrays
GB201318465D0 (en) 2013-10-18 2013-12-04 Oxford Nanopore Tech Ltd Method
GB201314695D0 (en) 2013-08-16 2013-10-02 Oxford Nanopore Tech Ltd Method
EP2964779B1 (en) 2013-03-08 2018-08-29 Oxford Nanopore Technologies Limited Use of spacer elements in a nucleic acid to control movement of a helicase
EP2971051A4 (en) 2013-03-15 2017-03-01 The Trustees of Columbia University in the City of New York Method for detecting multiple predetermined compounds in a sample
GB201313477D0 (en) 2013-07-29 2013-09-11 Univ Leuven Kath Nanopore biosensors for detection of proteins and nucleic acids
GB201316849D0 (en) 2013-09-23 2013-11-06 Isis Innovation Method
US9551697B2 (en) 2013-10-17 2017-01-24 Genia Technologies, Inc. Non-faradaic, capacitively coupled measurement in a nanopore cell array
GB201406151D0 (en) 2014-04-04 2014-05-21 Oxford Nanopore Tech Ltd Method
CN118086476A (zh) 2013-10-18 2024-05-28 牛津纳米孔科技公开有限公司 经修饰的酶
US9567630B2 (en) 2013-10-23 2017-02-14 Genia Technologies, Inc. Methods for forming lipid bilayers on biochips
WO2015061509A1 (en) 2013-10-23 2015-04-30 Genia Technologies, Inc. High speed molecular sensing with nanopores
DK3074534T3 (da) 2013-11-26 2019-07-29 Illumina Inc Fremgangsmåder til polynukleotidsekventering
EP2886663A1 (en) 2013-12-19 2015-06-24 Centre National de la Recherche Scientifique (CNRS) Nanopore sequencing using replicative polymerases and helicases
CN111534504B (zh) 2014-01-22 2024-06-21 牛津纳米孔科技公开有限公司 将一个或多个多核苷酸结合蛋白连接到靶多核苷酸的方法
GB201406155D0 (en) 2014-04-04 2014-05-21 Oxford Nanopore Tech Ltd Method
GB201403096D0 (en) 2014-02-21 2014-04-09 Oxford Nanopore Tech Ltd Sample preparation method
CA2943952A1 (en) 2014-03-24 2015-10-01 The Trustees Of Columbia University In The City Of New York Chemical methods for producing tagged nucleotides
CN106460061B (zh) 2014-04-04 2020-03-06 牛津纳米孔技术公司 在双链核酸分子的两端使用纳米孔和锚分子来表征所述双链核酸的方法
GB201417712D0 (en) 2014-10-07 2014-11-19 Oxford Nanopore Tech Ltd Method
CN106459159B (zh) 2014-05-02 2021-11-30 牛津纳米孔技术公司 突变孔
SG10201809900PA (en) 2014-07-31 2018-12-28 Illumina Inc Hybrid Nanopore Sensors
US10400014B2 (en) 2014-09-01 2019-09-03 Oxford Nanopore Technologies Ltd. Mutant CsgG pores
WO2016055778A1 (en) 2014-10-07 2016-04-14 Oxford Nanopore Technologies Limited Mutant pores
GB201418159D0 (en) 2014-10-14 2014-11-26 Oxford Nanopore Tech Ltd Method
EP3971300B1 (en) 2014-10-16 2024-06-05 Oxford Nanopore Technologies plc Sorting of polymers
GB201418512D0 (en) 2014-10-17 2014-12-03 Oxford Nanopore Tech Ltd Electrical device with detachable components
GB201418469D0 (en) 2014-10-17 2014-12-03 Oxford Nanopore Tech Ltd Method
AU2016212158B2 (en) 2015-01-26 2021-06-03 Allogene Therapeutics, Inc. mAb-driven chimeric antigen receptor systems for sorting/depleting engineered immune cells
GB201502810D0 (en) 2015-02-19 2015-04-08 Oxford Nanopore Tech Ltd Method
GB201502809D0 (en) 2015-02-19 2015-04-08 Oxford Nanopore Tech Ltd Mutant pore
CN107735686B (zh) 2015-04-14 2021-06-11 鲁汶天主教大学 具有内部蛋白质衔接子的纳米孔
CN109072295B (zh) 2015-12-08 2022-05-31 鲁汶大学研究与发展中心 修饰的纳米孔，包含其的组合物及其应用
US10975428B2 (en) 2016-03-02 2021-04-13 Oxford Nanopore Technologies Ltd. Mutant pore
CN118326018B (zh) 2016-04-06 2025-11-07 牛津纳米孔科技公开有限公司 突变体孔
GB201609221D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
EP4063521B1 (en) 2016-05-25 2024-02-21 Oxford Nanopore Technologies PLC Method of nanopore sequencing
GB201609220D0 (en) 2016-05-25 2016-07-06 Oxford Nanopore Tech Ltd Method
GB201611770D0 (en) 2016-07-06 2016-08-17 Oxford Nanopore Tech Microfluidic device
GB201616590D0 (en) 2016-09-29 2016-11-16 Oxford Nanopore Technologies Limited Method
JP2018059786A (ja) * 2016-10-04 2018-04-12 住友化学株式会社 嗅覚受容体複合体を用いた標的物質の検出装置及び検出方法並びに該検出装置の製造方法
GB201617886D0 (en) 2016-10-21 2016-12-07 Oxford Nanopore Technologies Limited Method
GB201620450D0 (en) 2016-12-01 2017-01-18 Oxford Nanopore Tech Ltd Method
CN119530363A (zh) 2017-02-10 2025-02-28 牛津纳米孔科技公开有限公司 修饰的纳米孔、包含其的组合物及其用途
GB201707140D0 (en) 2017-05-04 2017-06-21 Oxford Nanopore Tech Ltd Method
GB201707122D0 (en) 2017-05-04 2017-06-21 Oxford Nanopore Tech Ltd Pore
CN117106037B (zh) 2017-06-30 2025-07-25 弗拉芒区生物技术研究所 新颖蛋白孔
EP4303317A3 (en) * 2017-10-23 2024-04-24 F. Hoffmann-La Roche AG Removing and reinserting protein nanopores in a membrane using osmotic imbalance
GB2568895B (en) 2017-11-29 2021-10-27 Oxford Nanopore Tech Ltd Microfluidic device
GB201801768D0 (en) 2018-02-02 2018-03-21 Oxford Nanopore Tech Ltd Synthesis method
GB201807793D0 (en) 2018-05-14 2018-06-27 Oxford Nanopore Tech Ltd Method
GB201808556D0 (en) 2018-05-24 2018-07-11 Oxford Nanopore Tech Ltd Method
GB201809323D0 (en) 2018-06-06 2018-07-25 Oxford Nanopore Tech Ltd Method
GB201811623D0 (en) 2018-07-16 2018-08-29 Univ Oxford Innovation Ltd Molecular hopper
US20220162692A1 (en) 2018-07-30 2022-05-26 Oxford University Innovation Limited Assemblies
CN113195736A (zh) 2018-11-08 2021-07-30 牛津纳米孔科技公司 孔
GB201818216D0 (en) 2018-11-08 2018-12-26 Oxford Nanopore Tech Ltd Pore
GB201821155D0 (en) 2018-12-21 2019-02-06 Oxford Nanopore Tech Ltd Method
AU2020239385A1 (en) 2019-03-12 2021-08-26 Oxford Nanopore Technologies Plc Nanopore sensing device and methods of operation and of forming it
GB2580988B (en) 2019-03-19 2022-04-13 Oxford Nanopore Tech Ltd Current measurement apparatus, molecular entity sensing apparatus, method of measuring a current, method of sensing a molecular entity
AU2020272997A1 (en) 2019-04-09 2021-10-21 Oxford Nanopore Technologies Plc Pore
GB201907244D0 (en) 2019-05-22 2019-07-03 Oxford Nanopore Tech Ltd Method
GB201907246D0 (en) 2019-05-22 2019-07-03 Oxford Nanopore Tech Ltd Method
GB201913997D0 (en) 2019-09-27 2019-11-13 Oxford Nanopore Tech Ltd Method
GB201915480D0 (en) 2019-10-25 2019-12-11 Oxford Nanopore Tech Ltd Improved nanopore sensing device, components and method of manufacture
GB201917060D0 (en) 2019-11-22 2020-01-08 Oxford Nanopore Tech Ltd Method
JP2023503514A (ja) 2019-12-02 2023-01-30 オックスフォード ナノポール テクノロジーズ ピーエルシー ナノポアを使用する標的ペプチドの特徴付けの方法
GB201917742D0 (en) 2019-12-04 2020-01-15 Oxford Nanopore Tech Ltd Method
GB202004944D0 (en) 2020-04-03 2020-05-20 King S College London Method
GB202016874D0 (en) 2020-10-23 2020-12-09 Oxford Nanopore Tech Ltd Nanopore support structure and manufacture thereof
GB202009349D0 (en) 2020-06-18 2020-08-05 Oxford Nanopore Tech Ltd Method
US20240076729A9 (en) 2020-06-18 2024-03-07 Oxford Nanopore Technologies Plc Method
US20230295712A1 (en) 2020-06-18 2023-09-21 Oxford Nanopore Technologies Plc A method of selectively characterising a polynucleotide using a detector
KR20230038566A (ko) 2020-07-17 2023-03-20 옥스포드 나노포어 테크놀로지즈 피엘씨 나노포어 감지 디바이스
GB202015993D0 (en) 2020-10-08 2020-11-25 Oxford Nanopore Tech Ltd Method
GB202107192D0 (en) 2021-05-19 2021-06-30 Oxford Nanopore Tech Ltd Method
EP4341433A1 (en) 2021-05-19 2024-03-27 Oxford Nanopore Technologies PLC Methods for complement strand sequencing
GB202107354D0 (en) 2021-05-24 2021-07-07 Oxford Nanopore Tech Ltd Method
GB202112235D0 (en) 2021-08-26 2021-10-13 Oxford Nanopore Tech Ltd Nanopore
GB202118939D0 (en) 2021-12-23 2022-02-09 Oxford Nanopore Tech Plc Pore
GB202118906D0 (en) 2021-12-23 2022-02-09 Oxford Nanopore Tech Ltd Method
GB202118908D0 (en) 2021-12-23 2022-02-09 Oxford Nanopore Tech Ltd Method
GB202204919D0 (en) 2022-04-04 2022-05-18 Oxford Nanopore Tech Plc Method
GB202205617D0 (en) 2022-04-14 2022-06-01 Oxford Nanopore Tech Plc Novel modified protein pores and enzymes
WO2023222657A1 (en) 2022-05-17 2023-11-23 Oxford Nanopore Technologies Plc Method and adaptors
GB202211602D0 (en) 2022-08-09 2022-09-21 Oxford Nanopore Tech Plc Novel pore monomers and pores
GB202211607D0 (en) 2022-08-09 2022-09-21 Oxford Nanopore Tech Plc Novel pore monomers and pores
EP4569330A1 (en) 2022-08-09 2025-06-18 Oxford Nanopore Technologies PLC Novel pore monomers and pores
CA3262945A1 (en) 2022-08-09 2024-02-15 The Regents Of The University Of California DE NOVO PORES
CN120303290A (zh) 2022-10-28 2025-07-11 牛津纳米孔科技公开有限公司 孔单体和孔
GB202216162D0 (en) 2022-10-31 2022-12-14 Oxford Nanopore Tech Plc Method
GB202216905D0 (en) 2022-11-11 2022-12-28 Oxford Nanopore Tech Plc Novel pore monomers and pores
WO2024165853A1 (en) 2023-02-07 2024-08-15 Oxford University Innovation Limited Method of characterising a peptide, polypeptide or protein using a nanopore
GB202304324D0 (en) 2023-03-24 2023-05-10 Oxford Nanopore Tech Plc Method and kits
GB202305524D0 (en) 2023-04-14 2023-05-31 Oxford Nanopore Tech Plc Novel pore monomers and pores
GB202307141D0 (en) 2023-05-12 2023-06-28 Oxford Nanopore Tech Plc Modified helicases
GB202307486D0 (en) 2023-05-18 2023-07-05 Oxford Nanopore Tech Plc Method
GB202312709D0 (en) 2023-08-18 2023-10-04 Univ Oxford Innovation Ltd Nanopore
GB202313035D0 (en) 2023-08-25 2023-10-11 Univ Oxford Innovation Ltd Power unit
GB202315935D0 (en) 2023-10-18 2023-11-29 Oxford Nanopore Tech Ltd Novel enzymes
GB202317028D0 (en) 2023-11-06 2023-12-20 Oxford Nanopore Tech Ltd Method
WO2025160387A1 (en) * 2024-01-24 2025-07-31 The Rockefeller University Microscope for freestanding bilayer illumination
GB202405960D0 (en) 2024-04-29 2024-06-12 Oxford Nanopore Tech Plc Photo-active conjugates and their uses
GB202407055D0 (en) 2024-05-17 2024-07-03 Oxford Nanopore Tech Plc Enhanced polynucleotide sequencing
GB202407247D0 (en) 2024-05-21 2024-07-03 Oxford Nanopore Tech Plc Method
GB202407228D0 (en) 2024-05-21 2024-07-03 Oxford Nanopore Tech Plc Method

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3799743A (en) * 1971-11-22 1974-03-26 Alexander James Stable lysis responsive lipid bilayer
US6327410B1 (en) * 1997-03-14 2001-12-04 The Trustees Of Tufts College Target analyte sensors utilizing Microspheres
GB9712386D0 (en) * 1997-06-14 1997-08-13 Univ Coventry Biosensor
US6479288B1 (en) * 1998-02-17 2002-11-12 University Of Wales College Of Medicine Method and apparatus for introducing substances into the cell plasma membrane and/or cytosol
EP1107979B1 (en) * 1998-08-31 2006-07-05 Gryphon Therapeutics, Inc. Lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides
JP3665720B2 (ja) * 1999-09-24 2005-06-29 株式会社東芝 センサデバイス
NZ527036A (en) * 2001-01-18 2005-03-24 Univ Newcastle Ventures Ltd Biosensor or protein array comprising a membrane-spanning protein and a lipid membrane formed from amphiphilic molecules and membrane-spanning protein molecules
AU2003245272A1 (en) 2002-05-10 2003-11-11 The Texas A And M University System Stochastic sensing through covalent interactions
JP4394916B2 (ja) * 2003-09-19 2010-01-06 独立行政法人科学技術振興機構 人工脂質二重膜の形成装置および人工脂質二重膜の形成方法、並びにその利用
US8039247B2 (en) * 2004-01-21 2011-10-18 Japan Science And Technology Agency Method of forming planar lipid double membrane for membrane protein analysis and apparatus therefor

Also Published As

Publication number Publication date
WO2006100484A2 (en) 2006-09-28
US20080153150A1 (en) 2008-06-26
GB0505971D0 (en) 2005-04-27
WO2006100484A3 (en) 2008-05-29
EP1861071B1 (en) 2010-07-07
US7939270B2 (en) 2011-05-10
EP1861071A2 (en) 2007-12-05
ATE473438T1 (de) 2010-07-15
JP5253148B2 (ja) 2013-07-31
JP2008537106A (ja) 2008-09-11

Similar Documents

Publication Publication Date Title
DE602006015292D1 (de) Zuführung von molekülen an eine lipiddoppelschicht
BRPI0512396A (pt) polipeptìdeos biossintéticos utilizando aminoácidos codificados não naturalmente
BRPI0816426A2 (pt) Dispositivo para investigar uma molécula, método para investigar uma molécula, substrato adequado para uso no dispositivo para investigar moléculas, método para sequenciar um ácido nucléico.
WO2009121032A3 (en) Sample preparation devices and methods for processing analytes
WO2008121375A3 (en) Modified surfaces for immobilization of active molecules
WO2007001436A3 (en) Surface modification for non-specific adsorption of biological material
WO2006076703A3 (en) Porous biosensing device
CL2011000919A1 (es) Compuestos derivados de n-fenil-4-oxo-(1,4-dihidroquinolin o 1h-quinolin)-3-carboxamida, moduladores del regulador de conductancia transmembrana de fibrosis quistica (cftr); compuestos intermediarios; composicion farmaceutica; kit farmaceutico; proceso de preparacion; y uso para el tratamiento de fibrosis quistica, diabetes, entre otros.
WO2009020793A3 (en) Multi-polymer hydrogels
GB2433937A (en) Porous inorganic/organic hybrid materials with ordered domains for chromatographic separations and processes for their preparation
AU2013207599A1 (en) Process for determining one or more analytes in samples of biological origin having complex composition, and use thereof
EP2628746A3 (en) A process for concentration of a polypeptide
WO2009121034A3 (en) Multicapillary sample preparation devices and methods for processing analytes
WO2008093828A1 (ja) 生細胞表層分子解析方法及び部材
ATE505725T1 (de) Nukleinsäuredetektion mit poröser polymerelektrode
ATE458824T1 (de) Zellfreie in-vitro-transkription und translation von membranproteinen in gebundene planare lipidschichten
WO2006135793A3 (en) Protein engineering with analogous contact environments
WO2006079057A3 (en) Methods and compositions for specific inhibition of protein splicing by small molecules
WO2007062174A3 (en) Devices and methods for high-pressure refolding of proteins
DE602006014089D1 (de) Probeninjektor, probeninjektionsverfahren und vorrichtung zur flüssigkeitschromatographie
WO2011145126A3 (en) A method for the preparation of conjugates based on transglutaminase
WO2008124134A3 (en) High-pressure refolding of proteins in the presence of binding partners
WO2009122679A8 (ja) 透析膜
RU2008105242A (ru) Способ биотестирования загрязнителей (в частности вермипрепаратов)
DE602006010187D1 (de) Einzelsequenzhybridisierungssonden