JP5241484B2 - 内皮細胞増殖及び内皮細胞遊走を減弱するためのオピオイドアンタゴニストの使用 - Google Patents

内皮細胞増殖及び内皮細胞遊走を減弱するためのオピオイドアンタゴニストの使用 Download PDF

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JP5241484B2
JP5241484B2 JP2008500798A JP2008500798A JP5241484B2 JP 5241484 B2 JP5241484 B2 JP 5241484B2 JP 2008500798 A JP2008500798 A JP 2008500798A JP 2008500798 A JP2008500798 A JP 2008500798A JP 5241484 B2 JP5241484 B2 JP 5241484B2
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opioid
endothelial cell
vegf
proliferation
migration
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JP2008531749A (ja
JP2008531749A5 (https=
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ジョナサン モス
マーク リンゲン
パトリック エイ シングルトン
ジョー ジー エヌ ガルシア
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ザ ユニヴァーシティー オヴ シカゴ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
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    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Diabetes (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2008500798A 2005-03-07 2006-03-07 内皮細胞増殖及び内皮細胞遊走を減弱するためのオピオイドアンタゴニストの使用 Expired - Lifetime JP5241484B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US65919305P 2005-03-07 2005-03-07
US60/659,193 2005-03-07
US72570305P 2005-10-12 2005-10-12
US60/725,703 2005-10-12
US73100905P 2005-10-28 2005-10-28
US60/731,009 2005-10-28
US76085106P 2006-01-20 2006-01-20
US60/760,851 2006-01-20
PCT/US2006/007892 WO2006096626A2 (en) 2005-03-07 2006-03-07 Use of opioid antagonists to attenuate endothelial cell proliferation and migration

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JP2013009283A Division JP2013107892A (ja) 2005-03-07 2013-01-22 内皮細胞増殖及び内皮細胞遊走を減弱するためのオピオイドアンタゴニストの使用

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JP2008531749A JP2008531749A (ja) 2008-08-14
JP2008531749A5 JP2008531749A5 (https=) 2011-05-12
JP5241484B2 true JP5241484B2 (ja) 2013-07-17

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JP2008500798A Expired - Lifetime JP5241484B2 (ja) 2005-03-07 2006-03-07 内皮細胞増殖及び内皮細胞遊走を減弱するためのオピオイドアンタゴニストの使用
JP2013009283A Pending JP2013107892A (ja) 2005-03-07 2013-01-22 内皮細胞増殖及び内皮細胞遊走を減弱するためのオピオイドアンタゴニストの使用

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US (2) US9662390B2 (https=)
EP (1) EP1861096B1 (https=)
JP (2) JP5241484B2 (https=)
CN (2) CN101171010B (https=)
AU (1) AU2006220682B2 (https=)
BR (1) BRPI0608818A2 (https=)
CA (1) CA2600350C (https=)
ES (1) ES2714198T3 (https=)
MX (1) MX2007010833A (https=)
WO (1) WO2006096626A2 (https=)

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