JP5227492B2 - 癌におけるedgレセプター結合剤の使用 - Google Patents

癌におけるedgレセプター結合剤の使用 Download PDF

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Publication number
JP5227492B2
JP5227492B2 JP2004505027A JP2004505027A JP5227492B2 JP 5227492 B2 JP5227492 B2 JP 5227492B2 JP 2004505027 A JP2004505027 A JP 2004505027A JP 2004505027 A JP2004505027 A JP 2004505027A JP 5227492 B2 JP5227492 B2 JP 5227492B2
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JP
Japan
Prior art keywords
compound
administered
alkyl
formula
phosphate
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Expired - Fee Related
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JP2004505027A
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Japanese (ja)
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JP2005529921A5 (https=
JP2005529921A (ja
Inventor
トーマス・バウムルーカー
フォルカー・ブリンクマン
ケネス・リチャード・ラ・モンターニュ
ピーター・ティ・ラソタ
ディアナ・メヒチェリアコワ
ジャネット・マージョリー・ウッド
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ノバルティス アーゲー
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Priority claimed from GB0211261A external-priority patent/GB0211261D0/en
Priority claimed from GB0217150A external-priority patent/GB0217150D0/en
Application filed by ノバルティス アーゲー filed Critical ノバルティス アーゲー
Publication of JP2005529921A publication Critical patent/JP2005529921A/ja
Publication of JP2005529921A5 publication Critical patent/JP2005529921A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2004505027A 2002-05-16 2003-05-15 癌におけるedgレセプター結合剤の使用 Expired - Fee Related JP5227492B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB0211261.3 2002-05-16
GB0211261A GB0211261D0 (en) 2002-05-16 2002-05-16 Organic compounds
US39041102P 2002-06-20 2002-06-20
US60/390,411 2002-06-20
GB0217150A GB0217150D0 (en) 2002-07-24 2002-07-24 Organic compounds
GB0217150.2 2002-07-24
US44973903P 2003-02-24 2003-02-24
US60/449,739 2003-02-24
PCT/EP2003/005125 WO2003097028A1 (en) 2002-05-16 2003-05-15 Use of edg receptor binding agents in cancer

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2009289475A Division JP2010100637A (ja) 2002-05-16 2009-12-21 癌におけるedgレセプター結合剤の使用
JP2013009158A Division JP2013136584A (ja) 2002-05-16 2013-01-22 癌におけるedgレセプター結合剤の使用

Publications (3)

Publication Number Publication Date
JP2005529921A JP2005529921A (ja) 2005-10-06
JP2005529921A5 JP2005529921A5 (https=) 2006-06-29
JP5227492B2 true JP5227492B2 (ja) 2013-07-03

Family

ID=29554311

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2004505027A Expired - Fee Related JP5227492B2 (ja) 2002-05-16 2003-05-15 癌におけるedgレセプター結合剤の使用
JP2009289475A Withdrawn JP2010100637A (ja) 2002-05-16 2009-12-21 癌におけるedgレセプター結合剤の使用
JP2013009158A Pending JP2013136584A (ja) 2002-05-16 2013-01-22 癌におけるedgレセプター結合剤の使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2009289475A Withdrawn JP2010100637A (ja) 2002-05-16 2009-12-21 癌におけるedgレセプター結合剤の使用
JP2013009158A Pending JP2013136584A (ja) 2002-05-16 2013-01-22 癌におけるedgレセプター結合剤の使用

Country Status (22)

Country Link
US (2) US20090209495A1 (https=)
EP (3) EP1944026B1 (https=)
JP (3) JP5227492B2 (https=)
KR (1) KR20120125398A (https=)
CN (1) CN1652757B (https=)
AT (1) ATE412408T1 (https=)
AU (1) AU2003240655B2 (https=)
BR (1) BR0311173A (https=)
CA (1) CA2483594C (https=)
CY (1) CY1108719T1 (https=)
DE (1) DE60324416D1 (https=)
DK (1) DK1505959T3 (https=)
ES (1) ES2316758T3 (https=)
IL (3) IL164838A (https=)
MX (1) MXPA04011384A (https=)
NO (2) NO334074B1 (https=)
NZ (2) NZ560662A (https=)
PL (1) PL372103A1 (https=)
PT (1) PT1505959E (https=)
SI (1) SI1505959T1 (https=)
WO (1) WO2003097028A1 (https=)
ZA (1) ZA200408575B (https=)

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Also Published As

Publication number Publication date
CN1652757A (zh) 2005-08-10
HK1073606A1 (en) 2005-10-14
US20090209495A1 (en) 2009-08-20
US20140303257A1 (en) 2014-10-09
NZ536513A (en) 2007-10-26
CY1108719T1 (el) 2014-04-09
EP1944026B1 (en) 2013-06-26
AU2003240655A1 (en) 2003-12-02
JP2013136584A (ja) 2013-07-11
SI1505959T1 (sl) 2009-04-30
EP1944026A3 (en) 2011-06-01
EP1505959B1 (en) 2008-10-29
EP1955696A2 (en) 2008-08-13
JP2010100637A (ja) 2010-05-06
MXPA04011384A (es) 2005-02-14
HK1126127A1 (en) 2009-08-28
BR0311173A (pt) 2005-03-15
KR20120125398A (ko) 2012-11-14
DK1505959T3 (da) 2009-02-23
EP1955696A3 (en) 2011-05-25
NO20045312L (no) 2004-12-03
PT1505959E (pt) 2009-02-05
WO2003097028A1 (en) 2003-11-27
NO334074B1 (no) 2013-12-02
CA2483594C (en) 2011-02-15
IL164838A (en) 2013-12-31
ES2316758T3 (es) 2009-04-16
IL229550A0 (en) 2014-01-30
EP1505959A1 (en) 2005-02-16
EP1955696B1 (en) 2014-05-28
NZ560662A (en) 2009-09-25
PL372103A1 (en) 2005-07-11
CN1652757B (zh) 2012-02-08
DE60324416D1 (de) 2008-12-11
IL164838A0 (en) 2005-12-18
IL229559A0 (en) 2014-01-30
AU2003240655B2 (en) 2007-09-06
JP2005529921A (ja) 2005-10-06
CA2483594A1 (en) 2003-11-27
NO20130106L (no) 2004-12-03
ATE412408T1 (de) 2008-11-15
EP1944026A2 (en) 2008-07-16
ZA200408575B (en) 2005-07-27

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