CY1108719T1 - Χρηση των παραγοντων που προσδενονται στον edg υποδοχεα στον καρκινο - Google Patents

Χρηση των παραγοντων που προσδενονται στον edg υποδοχεα στον καρκινο

Info

Publication number
CY1108719T1
CY1108719T1 CY20091100091T CY091100091T CY1108719T1 CY 1108719 T1 CY1108719 T1 CY 1108719T1 CY 20091100091 T CY20091100091 T CY 20091100091T CY 091100091 T CY091100091 T CY 091100091T CY 1108719 T1 CY1108719 T1 CY 1108719T1
Authority
CY
Cyprus
Prior art keywords
edg
cancer
factors related
sphingosine
combination
Prior art date
Application number
CY20091100091T
Other languages
English (en)
Inventor
Thomas Baumruker
Volker Brinkmann
Montagne Kenneth Richard La
Peter T Lassota
Diana Mechtcheriakova
Jeanette Marjorie Wood
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0211261A external-priority patent/GB0211261D0/en
Priority claimed from GB0217150A external-priority patent/GB0217150D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1108719T1 publication Critical patent/CY1108719T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Παρέχεται μια μέθοδος για θεραπεία συμπαγών όγκων, π.χ. της επιθετικότητας του όγκου, και συγκεκριμένα αναστολής ή ελέγχου της απορρυθμισμένης αγγειογένεσης χρησιμοποιώντας έναν αγωνιστή υποδοχέα σφιγγοσίνης-1- φωσφορικού, προαιρετικά σε συνδυασμό με χημειοθεραπευτικό παράγοντα. Η εφεύρεση επίσης περιλαμβάνει έναν συνδυασμό ενός αγωνιστή υποδοχέα σφιγγοσίνης-1-φωσφορικού με έναν χημειοθεραπευτικό παράγοντα.
CY20091100091T 2002-05-16 2009-01-27 Χρηση των παραγοντων που προσδενονται στον edg υποδοχεα στον καρκινο CY1108719T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0211261A GB0211261D0 (en) 2002-05-16 2002-05-16 Organic compounds
US39041102P 2002-06-20 2002-06-20
GB0217150A GB0217150D0 (en) 2002-07-24 2002-07-24 Organic compounds
US44973903P 2003-02-24 2003-02-24
EP03730049A EP1505959B1 (en) 2002-05-16 2003-05-15 Use of edg receptor binding agents in cancer

Publications (1)

Publication Number Publication Date
CY1108719T1 true CY1108719T1 (el) 2014-04-09

Family

ID=29554311

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100091T CY1108719T1 (el) 2002-05-16 2009-01-27 Χρηση των παραγοντων που προσδενονται στον edg υποδοχεα στον καρκινο

Country Status (23)

Country Link
US (2) US20090209495A1 (el)
EP (3) EP1955696B1 (el)
JP (3) JP5227492B2 (el)
KR (1) KR20120125398A (el)
CN (1) CN1652757B (el)
AT (1) ATE412408T1 (el)
AU (1) AU2003240655B2 (el)
BR (1) BR0311173A (el)
CA (1) CA2483594C (el)
CY (1) CY1108719T1 (el)
DE (1) DE60324416D1 (el)
DK (1) DK1505959T3 (el)
ES (1) ES2316758T3 (el)
HK (2) HK1073606A1 (el)
IL (3) IL164838A (el)
MX (1) MXPA04011384A (el)
NO (2) NO334074B1 (el)
NZ (2) NZ536513A (el)
PL (1) PL372103A1 (el)
PT (1) PT1505959E (el)
SI (1) SI1505959T1 (el)
WO (1) WO2003097028A1 (el)
ZA (1) ZA200408575B (el)

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Also Published As

Publication number Publication date
ZA200408575B (en) 2005-07-27
ES2316758T3 (es) 2009-04-16
EP1944026A3 (en) 2011-06-01
DE60324416D1 (de) 2008-12-11
CA2483594C (en) 2011-02-15
BR0311173A (pt) 2005-03-15
IL229550A0 (en) 2014-01-30
SI1505959T1 (sl) 2009-04-30
EP1955696A3 (en) 2011-05-25
CN1652757B (zh) 2012-02-08
US20090209495A1 (en) 2009-08-20
EP1505959B1 (en) 2008-10-29
CN1652757A (zh) 2005-08-10
ATE412408T1 (de) 2008-11-15
CA2483594A1 (en) 2003-11-27
NO20130106L (no) 2004-12-03
EP1944026B1 (en) 2013-06-26
US20140303257A1 (en) 2014-10-09
HK1073606A1 (en) 2005-10-14
IL164838A0 (en) 2005-12-18
EP1944026A2 (en) 2008-07-16
NO20045312L (no) 2004-12-03
HK1126127A1 (en) 2009-08-28
EP1955696B1 (en) 2014-05-28
EP1505959A1 (en) 2005-02-16
AU2003240655B2 (en) 2007-09-06
NZ536513A (en) 2007-10-26
PT1505959E (pt) 2009-02-05
JP5227492B2 (ja) 2013-07-03
JP2005529921A (ja) 2005-10-06
KR20120125398A (ko) 2012-11-14
NO334074B1 (no) 2013-12-02
IL164838A (en) 2013-12-31
DK1505959T3 (da) 2009-02-23
JP2010100637A (ja) 2010-05-06
PL372103A1 (en) 2005-07-11
MXPA04011384A (es) 2005-02-14
AU2003240655A1 (en) 2003-12-02
NZ560662A (en) 2009-09-25
EP1955696A2 (en) 2008-08-13
JP2013136584A (ja) 2013-07-11
IL229559A0 (en) 2014-01-30
WO2003097028A1 (en) 2003-11-27

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