CY1108719T1 - Χρηση των παραγοντων που προσδενονται στον edg υποδοχεα στον καρκινο - Google Patents
Χρηση των παραγοντων που προσδενονται στον edg υποδοχεα στον καρκινοInfo
- Publication number
- CY1108719T1 CY1108719T1 CY20091100091T CY091100091T CY1108719T1 CY 1108719 T1 CY1108719 T1 CY 1108719T1 CY 20091100091 T CY20091100091 T CY 20091100091T CY 091100091 T CY091100091 T CY 091100091T CY 1108719 T1 CY1108719 T1 CY 1108719T1
- Authority
- CY
- Cyprus
- Prior art keywords
- edg
- cancer
- factors related
- sphingosine
- combination
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title 1
- 229940121846 Sphingosine 1-phosphate receptor agonist Drugs 0.000 abstract 2
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 229940127089 cytotoxic agent Drugs 0.000 abstract 2
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 230000001276 controlling effect Effects 0.000 abstract 1
- 230000002074 deregulated effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0211261A GB0211261D0 (en) | 2002-05-16 | 2002-05-16 | Organic compounds |
| US39041102P | 2002-06-20 | 2002-06-20 | |
| GB0217150A GB0217150D0 (en) | 2002-07-24 | 2002-07-24 | Organic compounds |
| US44973903P | 2003-02-24 | 2003-02-24 | |
| EP03730049A EP1505959B1 (en) | 2002-05-16 | 2003-05-15 | Use of edg receptor binding agents in cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108719T1 true CY1108719T1 (el) | 2014-04-09 |
Family
ID=29554311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20091100091T CY1108719T1 (el) | 2002-05-16 | 2009-01-27 | Χρηση των παραγοντων που προσδενονται στον edg υποδοχεα στον καρκινο |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US20090209495A1 (https=) |
| EP (3) | EP1944026B1 (https=) |
| JP (3) | JP5227492B2 (https=) |
| KR (1) | KR20120125398A (https=) |
| CN (1) | CN1652757B (https=) |
| AT (1) | ATE412408T1 (https=) |
| AU (1) | AU2003240655B2 (https=) |
| BR (1) | BR0311173A (https=) |
| CA (1) | CA2483594C (https=) |
| CY (1) | CY1108719T1 (https=) |
| DE (1) | DE60324416D1 (https=) |
| DK (1) | DK1505959T3 (https=) |
| ES (1) | ES2316758T3 (https=) |
| IL (3) | IL164838A (https=) |
| MX (1) | MXPA04011384A (https=) |
| NO (2) | NO334074B1 (https=) |
| NZ (2) | NZ560662A (https=) |
| PL (1) | PL372103A1 (https=) |
| PT (1) | PT1505959E (https=) |
| SI (1) | SI1505959T1 (https=) |
| WO (1) | WO2003097028A1 (https=) |
| ZA (1) | ZA200408575B (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20010688A1 (it) | 2001-11-21 | 2003-05-21 | Univ Roma | Composti immunoregolatori. |
| BR0306811A (pt) | 2002-01-11 | 2004-10-26 | Sankyo Co | Composto, éster farmacologicamente aceitável do mesmo, composição farmacêutica e métodos para prevenção ou tratamento de doenças autoimunes, da artrite reumatóide e da rejeição causada pelo transplante de vários órgãos em um mamìfero |
| CA2488425A1 (en) | 2002-06-07 | 2003-12-18 | Es Cell International Pte Ltd | Methods of regulating differentiation in stem cells |
| US7456157B2 (en) * | 2003-02-18 | 2008-11-25 | Kyorin Pharmaceutical Co., Ltd. | Aminophosphonic acid derivatives, addition salts thereof and S1P receptor modulators |
| GB0500020D0 (en) * | 2005-01-04 | 2005-02-09 | Novartis Ag | Organic compounds |
| JP2005272453A (ja) | 2004-02-24 | 2005-10-06 | Sankyo Co Ltd | アミノアルコール化合物 |
| US7794713B2 (en) | 2004-04-07 | 2010-09-14 | Lpath, Inc. | Compositions and methods for the treatment and prevention of hyperproliferative diseases |
| US8022225B2 (en) | 2004-08-04 | 2011-09-20 | Taisho Pharmaceutical Co., Ltd | Triazole derivative |
| MX2007001661A (es) | 2004-08-13 | 2007-04-23 | Praecis Pharm Inc | Metodos y composiciones para modular la actividad del receptor de esfingosina -1 fosfato (sip). |
| EP1812797B1 (en) * | 2004-10-28 | 2013-03-20 | Lpath, Inc. | Compositions and methods for the treatment and prevention of hyperproliferative diseases |
| GB0513431D0 (en) | 2005-06-30 | 2005-08-10 | Kherion Technology Ltd | Prophylactic compositions and uses |
| GT200600350A (es) * | 2005-08-09 | 2007-03-28 | Formulaciones líquidas | |
| EP1988083B1 (en) | 2006-02-03 | 2014-04-02 | Taisho Pharmaceutical Co., Ltd. | Triazole derivative |
| JP5218737B2 (ja) | 2006-02-06 | 2013-06-26 | 大正製薬株式会社 | スフィンゴシン−1−リン酸結合阻害物質 |
| AU2007234380A1 (en) * | 2006-04-06 | 2007-10-11 | Novartis Ag | Combination of organic compounds |
| US7862812B2 (en) | 2006-05-31 | 2011-01-04 | Lpath, Inc. | Methods for decreasing immune response and treating immune conditions |
| GB0612721D0 (en) * | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
| EP1923058A1 (en) * | 2006-09-26 | 2008-05-21 | Novartis AG | Coated pharmaceutical composition comprising an S1P agonist or modulator |
| EP2083862A4 (en) * | 2006-10-27 | 2012-09-19 | Lpath Inc | COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASES AND DISORDERS |
| DK2177512T3 (da) | 2007-08-01 | 2012-06-18 | Taisho Pharmaceutical Co Ltd | S1P1-bindingshæmmer |
| EP2177521A1 (en) | 2008-10-14 | 2010-04-21 | Almirall, S.A. | New 2-Amidothiadiazole Derivatives |
| CA2743232C (en) * | 2008-11-11 | 2015-12-29 | Novartis Ag | Crystalline forms of fingolimod hcl |
| MX2011004924A (es) | 2008-11-11 | 2011-05-30 | Novartis Ag | Sales de fingolimod. |
| CN105213372A (zh) | 2008-12-22 | 2016-01-06 | 诺华股份有限公司 | S1p受体激动剂的给药方案 |
| RS66784B9 (sr) | 2008-12-22 | 2025-08-29 | Novartis Ag | Režim doziranјa agonista s1p receptora |
| EP2202232A1 (en) | 2008-12-26 | 2010-06-30 | Laboratorios Almirall, S.A. | 1,2,4-oxadiazole derivatives and their therapeutic use |
| EP2210890A1 (en) | 2009-01-19 | 2010-07-28 | Almirall, S.A. | Oxadiazole derivatives as S1P1 receptor agonists |
| EP2456752A2 (en) * | 2009-07-24 | 2012-05-30 | ratiopharm GmbH | Process for producing fingolimod salts |
| EP2305660A1 (en) | 2009-09-25 | 2011-04-06 | Almirall, S.A. | New thiadiazole derivatives |
| EP2482810A2 (en) | 2009-09-29 | 2012-08-08 | Novartis AG | Dosage regimen of an s1p receptor modulator |
| EP2343287A1 (en) | 2009-12-10 | 2011-07-13 | Almirall, S.A. | New 2-aminothiadiazole derivatives |
| EP2366702A1 (en) | 2010-03-18 | 2011-09-21 | Almirall, S.A. | New oxadiazole derivatives |
| EP2390252A1 (en) | 2010-05-19 | 2011-11-30 | Almirall, S.A. | New pyrazole derivatives |
| WO2012071524A1 (en) | 2010-11-24 | 2012-05-31 | Ratiopharm Gmbh | Arylsulfonate salts of fingolimod and processes for preparation thereof |
| FR2968556B1 (fr) | 2010-12-13 | 2013-12-27 | Centre Nat Rech Scient | Inhibiteurs des infections a vih et leurs utilisations |
| BR112013017302B1 (pt) | 2011-01-07 | 2021-12-07 | Novartis Ag | Composição farmacêutica em fase sólida |
| UA113507C2 (xx) | 2011-02-07 | 2017-02-10 | Модулятори s1p | |
| PH12014500854A1 (en) | 2011-10-21 | 2021-08-09 | Novartis Ag | Dosage regimen for an s1p receptor modulator or agonist |
| JP6033791B2 (ja) * | 2011-12-23 | 2016-11-30 | Meiji Seikaファルマ株式会社 | 新規s1p受容体調整薬 |
| WO2014025708A1 (en) | 2012-08-06 | 2014-02-13 | Biogen Idec Ma Inc. | Compounds that are s1p modulating agents and/or atx modulating agents |
| WO2014025709A1 (en) | 2012-08-06 | 2014-02-13 | Biogen Idec Ma Inc. | Compounds that are s1p modulating agents and/or atx modulating agents |
| ES2636596T3 (es) | 2012-11-20 | 2017-10-06 | Biogen Ma Inc. | Agentes moduladores de S1P y/o ATX |
| WO2014081756A1 (en) | 2012-11-20 | 2014-05-30 | Biogen Idec Ma Inc. | S1p and/or atx modulating agents |
| CA2899322A1 (en) | 2013-01-29 | 2014-08-07 | Biogen Ma Inc. | S1p modulating agents |
| US20160039825A1 (en) | 2013-03-15 | 2016-02-11 | Biogen Ma Inc. | S1p and/or atx modulating agents |
| CN103417970A (zh) * | 2013-08-15 | 2013-12-04 | 泰山医学院 | 雌激素上调内皮系统保护分子鞘氨醇1-磷酸的应用 |
| WO2016135644A1 (en) | 2015-02-26 | 2016-09-01 | Novartis Ag | Treatment of autoimmune disease in a patient receiving additionally a beta-blocker |
| US11434200B2 (en) | 2017-03-09 | 2022-09-06 | Novartis Ag | Solid forms comprising an oxime ether compound and a coformer, compositions and methods of use thereof |
| EP3443986A1 (en) | 2017-08-17 | 2019-02-20 | AC BioScience | Enhancement of chemotherapy efficiency by sphingosine-1-phosphate |
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-
2003
- 2003-05-15 PL PL03372103A patent/PL372103A1/xx not_active IP Right Cessation
- 2003-05-15 ES ES03730049T patent/ES2316758T3/es not_active Expired - Lifetime
- 2003-05-15 SI SI200331499T patent/SI1505959T1/sl unknown
- 2003-05-15 EP EP08152489.4A patent/EP1944026B1/en not_active Expired - Lifetime
- 2003-05-15 CA CA2483594A patent/CA2483594C/en not_active Expired - Fee Related
- 2003-05-15 AU AU2003240655A patent/AU2003240655B2/en not_active Ceased
- 2003-05-15 JP JP2004505027A patent/JP5227492B2/ja not_active Expired - Fee Related
- 2003-05-15 DK DK03730049T patent/DK1505959T3/da active
- 2003-05-15 WO PCT/EP2003/005125 patent/WO2003097028A1/en not_active Ceased
- 2003-05-15 EP EP03730049A patent/EP1505959B1/en not_active Expired - Lifetime
- 2003-05-15 KR KR1020127025694A patent/KR20120125398A/ko not_active Ceased
- 2003-05-15 AT AT03730049T patent/ATE412408T1/de active
- 2003-05-15 DE DE60324416T patent/DE60324416D1/de not_active Expired - Lifetime
- 2003-05-15 NZ NZ560662A patent/NZ560662A/en not_active IP Right Cessation
- 2003-05-15 CN CN038111942A patent/CN1652757B/zh not_active Expired - Fee Related
- 2003-05-15 BR BR0311173-3A patent/BR0311173A/pt not_active IP Right Cessation
- 2003-05-15 EP EP08152484.5A patent/EP1955696B1/en not_active Expired - Lifetime
- 2003-05-15 NZ NZ536513A patent/NZ536513A/en not_active IP Right Cessation
- 2003-05-15 MX MXPA04011384A patent/MXPA04011384A/es active IP Right Grant
- 2003-05-15 PT PT03730049T patent/PT1505959E/pt unknown
-
2004
- 2004-10-22 ZA ZA2004/08575A patent/ZA200408575B/en unknown
- 2004-10-25 IL IL164838A patent/IL164838A/en not_active IP Right Cessation
- 2004-12-03 NO NO20045312A patent/NO334074B1/no not_active IP Right Cessation
-
2009
- 2009-01-27 CY CY20091100091T patent/CY1108719T1/el unknown
- 2009-04-09 US US12/420,913 patent/US20090209495A1/en not_active Abandoned
- 2009-12-21 JP JP2009289475A patent/JP2010100637A/ja not_active Withdrawn
-
2013
- 2013-01-17 NO NO20130106A patent/NO20130106L/no not_active Application Discontinuation
- 2013-01-22 JP JP2013009158A patent/JP2013136584A/ja active Pending
- 2013-11-21 IL IL229559A patent/IL229559A0/en unknown
- 2013-11-21 IL IL229550A patent/IL229550A0/en unknown
-
2014
- 2014-06-23 US US14/311,838 patent/US20140303257A1/en not_active Abandoned
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