JP5214436B2 - 置換された環状尿素誘導体及び医薬の製造へのその使用 - Google Patents

置換された環状尿素誘導体及び医薬の製造へのその使用 Download PDF

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JP5214436B2
JP5214436B2 JP2008506989A JP2008506989A JP5214436B2 JP 5214436 B2 JP5214436 B2 JP 5214436B2 JP 2008506989 A JP2008506989 A JP 2008506989A JP 2008506989 A JP2008506989 A JP 2008506989A JP 5214436 B2 JP5214436 B2 JP 5214436B2
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JP2008538366A (ja
JP2008538366A5 (de
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フランク・ローベルト
ズンダーマン・ベルント
シック・ハンス
ゾンネンシャイン・ヘルムート
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グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/10Oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
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    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
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    • C07D235/28Sulfur atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
JP2008506989A 2005-04-19 2006-04-18 置換された環状尿素誘導体及び医薬の製造へのその使用 Expired - Fee Related JP5214436B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005018191.0 2005-04-19
DE102005018191A DE102005018191A1 (de) 2005-04-19 2005-04-19 Substituierte zyklische Harnstoff-Derivate und deren Verwendung zur Herstellung von Arzneimitteln
PCT/EP2006/003519 WO2006111346A1 (de) 2005-04-19 2006-04-18 Substituierte zyklische harnstoff-derivate und deren verwendung als vanilloid-rezeptor 1 modulatoren

Publications (3)

Publication Number Publication Date
JP2008538366A JP2008538366A (ja) 2008-10-23
JP2008538366A5 JP2008538366A5 (de) 2013-02-14
JP5214436B2 true JP5214436B2 (ja) 2013-06-19

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JP2008506989A Expired - Fee Related JP5214436B2 (ja) 2005-04-19 2006-04-18 置換された環状尿素誘導体及び医薬の製造へのその使用

Country Status (8)

Country Link
US (1) US8207182B2 (de)
EP (1) EP1874733B1 (de)
JP (1) JP5214436B2 (de)
CA (1) CA2605144C (de)
DE (1) DE102005018191A1 (de)
ES (1) ES2386796T3 (de)
PL (1) PL1874733T3 (de)
WO (1) WO2006111346A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008029168A2 (en) * 2006-09-08 2008-03-13 Summit Corporation Plc Treatment of duchenne muscular dystrophy
JP5643112B2 (ja) 2008-01-28 2014-12-17 アモーレパシフィック コーポレイションAmorepacific Corporation バニロイド受容体としての新規化合物、その異性体または薬剤学的に許容し得る塩、及びこれを含有する医薬組成物
KR101621444B1 (ko) 2008-07-02 2016-05-19 (주)아모레퍼시픽 바닐로이드 수용체 길항제로 작용하는 신규 화합물, 이의 이성질체 또는 이의 약제학적으로 허용 가능한 염, 및 이를 포함하는 약학 조성물
EP2464631A1 (de) * 2009-08-12 2012-06-20 Technion Research & Development Foundation Ltd. Polycyclische verbindungen mit der bezeichnung calixurene und ihre verwendungen
US8815265B2 (en) 2010-06-30 2014-08-26 Avon Products, Inc. Cosmetic use of N-substituted sulfonyloxybenzylamines and related compounds
CN110049971B (zh) * 2016-10-06 2023-01-13 日产化学株式会社 二胺、聚合物、液晶取向剂、液晶取向膜及液晶表示元件

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670368A1 (de) * 1966-07-16 1970-11-05 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung aralkylsubstituierter Lactame und Cyclischer Harnstoffe
JPS588503B2 (ja) 1974-12-27 1983-02-16 富士写真フイルム株式会社 カラ−シヤシンカンコウザイリヨウ
JPS58203976A (ja) * 1982-05-24 1983-11-28 Sumitomo Chem Co Ltd ベンズイミダゾリン−2−チオン誘導体の製造法
JPS63170011A (ja) * 1987-01-07 1988-07-13 Mitsubishi Monsanto Chem Co アミド系樹脂成形品およびその製造法
GB8724912D0 (en) 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
DE4300912A1 (de) * 1993-01-15 1994-07-21 Merck Patent Gmbh Chinazolinderivate
FR2722190B1 (fr) * 1994-07-05 1996-10-04 Sanofi Sa Derives de 1-benzyl-1,3-dihydro-2h-benzimidazol-2-one, leur preparation, les compositions pharmaceutique en contenant
US5612363A (en) * 1995-06-02 1997-03-18 Berlex Laboratories, Inc. N,N-di(aryl) cyclic urea derivatives as anti-coagulants
AU1592697A (en) * 1995-08-22 1997-03-19 Du Pont Merck Pharmaceutical Company, The Substituted cyclic ureas and derivatives thereof useful as retroviral protease inhibitors
CN100439332C (zh) * 2000-08-21 2008-12-03 株式会社太平洋 硫脲衍生物以及包含该衍生物的药物组合物
WO2004103281A2 (en) * 2003-05-16 2004-12-02 Georgetown University Vanilloid receptor antagonists, and methods of making and using them
WO2006104280A1 (ja) * 2005-03-31 2006-10-05 Takeda Pharmaceutical Company Limited 糖尿病の予防・治療剤

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Publication number Publication date
ES2386796T3 (es) 2012-08-30
US8207182B2 (en) 2012-06-26
EP1874733A1 (de) 2008-01-09
JP2008538366A (ja) 2008-10-23
CA2605144A1 (en) 2006-10-26
CA2605144C (en) 2014-05-27
WO2006111346A1 (de) 2006-10-26
DE102005018191A1 (de) 2006-10-26
US20080090855A1 (en) 2008-04-17
EP1874733B1 (de) 2012-06-20
PL1874733T3 (pl) 2012-09-28

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