JP5110697B2 - 固形製剤 - Google Patents

固形製剤 Download PDF

Info

Publication number
JP5110697B2
JP5110697B2 JP2007558257A JP2007558257A JP5110697B2 JP 5110697 B2 JP5110697 B2 JP 5110697B2 JP 2007558257 A JP2007558257 A JP 2007558257A JP 2007558257 A JP2007558257 A JP 2007558257A JP 5110697 B2 JP5110697 B2 JP 5110697B2
Authority
JP
Japan
Prior art keywords
tablet
angiotensin
solid preparation
calcium
antagonist
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2007558257A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008543729A (ja
JP2008543729A5 (enrdf_load_stackoverflow
Inventor
健司 濱浦
充 菅野
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Priority to JP2007558257A priority Critical patent/JP5110697B2/ja
Publication of JP2008543729A publication Critical patent/JP2008543729A/ja
Publication of JP2008543729A5 publication Critical patent/JP2008543729A5/ja
Application granted granted Critical
Publication of JP5110697B2 publication Critical patent/JP5110697B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2007558257A 2005-06-27 2006-06-26 固形製剤 Active JP5110697B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2007558257A JP5110697B2 (ja) 2005-06-27 2006-06-26 固形製剤

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2005187214 2005-06-27
JP2005187214 2005-06-27
PCT/JP2006/313176 WO2007001067A2 (en) 2005-06-27 2006-06-26 Solid dosage form comprising an angiotensin ii receptor antagonist and a calcium channel blocker
JP2007558257A JP5110697B2 (ja) 2005-06-27 2006-06-26 固形製剤

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012177601A Division JP5456857B2 (ja) 2005-06-27 2012-08-09 固形製剤

Publications (3)

Publication Number Publication Date
JP2008543729A JP2008543729A (ja) 2008-12-04
JP2008543729A5 JP2008543729A5 (enrdf_load_stackoverflow) 2009-08-06
JP5110697B2 true JP5110697B2 (ja) 2012-12-26

Family

ID=37460221

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007558257A Active JP5110697B2 (ja) 2005-06-27 2006-06-26 固形製剤
JP2012177601A Active JP5456857B2 (ja) 2005-06-27 2012-08-09 固形製剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012177601A Active JP5456857B2 (ja) 2005-06-27 2012-08-09 固形製剤

Country Status (3)

Country Link
JP (2) JP5110697B2 (enrdf_load_stackoverflow)
TW (1) TWI388345B (enrdf_load_stackoverflow)
WO (1) WO2007001067A2 (enrdf_load_stackoverflow)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5241511B2 (ja) * 2006-12-26 2013-07-17 第一三共株式会社 溶出性の改善された医薬組成物
JP5241512B2 (ja) * 2006-12-26 2013-07-17 第一三共株式会社 溶出性改善方法
JP5241510B2 (ja) * 2006-12-26 2013-07-17 第一三共株式会社 固形製剤

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6469753B1 (en) 1996-05-03 2002-10-22 Starsight Telecast, Inc. Information system
GT200600371A (es) * 2005-08-17 2007-03-21 Formas de dosis sólidas de valsartan y amlodipina y método para hacer las mismas
US9113107B2 (en) 2005-11-08 2015-08-18 Rovi Guides, Inc. Interactive advertising and program promotion in an interactive television system
US20100237530A1 (en) * 2006-06-27 2010-09-23 Daiichi Sankyo Company, Limited Compressed preparation
US20080175872A1 (en) * 2006-09-28 2008-07-24 Osmotica Corp. Controlled Release Dosage Form Containing Lercanidipine and a Performance-enhancing Acid
US8832742B2 (en) 2006-10-06 2014-09-09 United Video Properties, Inc. Systems and methods for acquiring, categorizing and delivering media in interactive media guidance applications
KR101247583B1 (ko) * 2006-12-08 2013-03-26 한미사이언스 주식회사 암로디핀 또는 이의 약제학적 허용가능한 염, 및 로자탄또는 이의 약제학적 허용가능한 염을 함유하는 약제학적조성물
US20110027356A1 (en) * 2008-01-25 2011-02-03 Duo-Ge Combination of Oral Medicaments Bonded by a Wrapping
WO2009113420A1 (ja) * 2008-03-13 2009-09-17 第一三共株式会社 オルメサルタンメドキソミルを含む製剤の溶出性の改善
UY32126A (es) * 2008-09-25 2010-04-30 Takeda Pharmaceutical Composición farmacéutica sólida
CN102292085B (zh) * 2009-01-23 2017-01-18 韩美科学株式会社 包含氨氯地平和氯沙坦的固体药物组合物及其制备方法
UA103688C2 (uk) * 2009-06-30 2013-11-11 Санофі Тверді фармацевтичні композиції з фіксованою дозою, що містять ірбесартан і амлодипін, їх отримання і їх терапевтичне застосування
JP5886530B2 (ja) * 2010-02-26 2016-03-16 第一三共株式会社 錠剤
JP5421945B2 (ja) * 2010-03-10 2014-02-19 大日本住友製薬株式会社 イルベサルタンとアムロジピンまたはその塩を含有する医薬組成物
JP5824222B2 (ja) * 2010-03-31 2015-11-25 第一三共株式会社 固形製剤の製造方法
EP2632438A1 (en) * 2010-10-27 2013-09-04 KRKA, tovarna zdravil, d.d., Novo mesto Multilayer pharmaceutical composition comprising telmisartan and amlodipine
UY33772A (es) * 2010-12-09 2012-07-31 Lg Life Sciences Ltd Composición farmacéutica que comprende clorhidrato de lercanidipina y valsartán como componentes activos y a un método para la preparacion de la misma.
JP6041591B2 (ja) * 2011-09-13 2016-12-14 大日本住友製薬株式会社 イルベサルタンとアムロジピンまたはその塩を含有する安定化された医薬組成物
JP5854371B2 (ja) * 2012-10-12 2016-02-09 味の素株式会社 カルシウム拮抗薬／アンジオテンシンｉｉ受容体拮抗薬含有医薬製剤
MX2013001277A (es) * 2013-01-31 2014-07-30 Miguel Ángel García Pérez Composicion farmaceutica con un antagonista de los receptores de la angiotensina ii y un bloqueador de los canales de calcio para el tratamiento de la hipertension arterial.
CN103127110A (zh) * 2013-03-18 2013-06-05 吉林省博大伟业制药有限公司 含有血管紧张素ⅱ受体拮抗剂和钙通道阻断剂的复方制剂
CN103271908B (zh) * 2013-05-23 2019-02-12 浙江华海药业股份有限公司 含有替米沙坦和苯磺酸氨氯地平的口服片剂及其制备方法
ES2847904T3 (es) * 2013-07-23 2021-08-04 Daiichi Sankyo Co Ltd Medicamento para la prevención o el tratamiento de la hipertensión
CN103908539B (zh) * 2014-05-03 2017-02-01 李全浩 一种治疗高血压的中药组合物及其制备方法及应用
CN104000821B (zh) * 2014-06-02 2020-06-19 浙江华海药业股份有限公司 含有替米沙坦和苯磺酸氨氯地平的口服双层片剂及其制备方法
WO2016114725A1 (en) * 2015-01-12 2016-07-21 İlko İtaç Sanayi Ve Ticaret Anonim Şirketi A stable bilayer pharmaceutical tablet compositions comprising fixed dose of irbesartan and amlodipine
CA3015964C (en) * 2016-03-24 2021-08-03 Daiichi Sankyo Company, Limited Medicine for treating renal disease
CN109432034A (zh) * 2018-12-28 2019-03-08 乐普制药科技有限公司 一种缬沙坦氨氯地平三层片剂及其制备方法
CN110237073B (zh) * 2019-07-10 2022-12-02 安庆回音必制药股份有限公司 一种奥美沙坦酯氨氯地平片及其制备方法
CN114712319B (zh) * 2022-03-25 2024-01-09 北京诺康达医药科技股份有限公司 一种非洛地平盐酸普萘洛尔复方制剂及其制备方法
CN115227662B (zh) * 2022-06-24 2023-11-24 辰欣药业股份有限公司 一种缬沙坦氨氯地平片剂及其制备方法
CN115944600B (zh) * 2022-12-01 2024-05-28 山东齐都药业有限公司 含有替米沙坦和苯磺酸氨氯地平的口服片剂及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0859470A (ja) * 1994-08-29 1996-03-05 Sankyo Co Ltd シクロペンタ［ｄ］ピリミジン誘導体の溶出性改善製剤
US6395728B2 (en) * 1999-07-08 2002-05-28 Novartis Ag Method of treatment and pharmaceutical composition
AU2002242676B2 (en) * 2002-01-16 2008-05-29 Boehringer Ingelheim Pharma Gmbh & Co. Kg Bilayer pharmaceutical tablet comprising telmisartan and a diuretic and preparation thereof
JP3751287B2 (ja) * 2002-03-27 2006-03-01 バイエル薬品株式会社 小型化されたニフェジピン有核錠剤
WO2003080057A1 (fr) * 2002-03-27 2003-10-02 Bayer Aktiengesellschaft Comprime-noyau de taille reduite contenant de la nifedipine
EG24716A (en) * 2002-05-17 2010-06-07 Novartis Ag Combination of organic compounds
US20040198789A1 (en) * 2003-02-28 2004-10-07 Recordati Ireland Limited Lercanidipine/ARB/diuretic therapeutic combinations
JP2004300102A (ja) * 2003-03-31 2004-10-28 Kissei Pharmaceut Co Ltd 縮合複素環誘導体、それを含有する医薬組成物およびその医薬用途
WO2005070463A2 (en) * 2004-01-12 2005-08-04 Sepracor, Inc. Compositions comprising (s)-amlodipine malate and an angiotensin receptor blocker and methods of their use
JP5134963B2 (ja) * 2004-11-05 2013-01-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング テルミサルタンとアムロジピンを含む二層錠剤

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5241511B2 (ja) * 2006-12-26 2013-07-17 第一三共株式会社 溶出性の改善された医薬組成物
JP5241512B2 (ja) * 2006-12-26 2013-07-17 第一三共株式会社 溶出性改善方法
JP5241510B2 (ja) * 2006-12-26 2013-07-17 第一三共株式会社 固形製剤

Also Published As

Publication number Publication date
JP5456857B2 (ja) 2014-04-02
JP2012236853A (ja) 2012-12-06
WO2007001067A3 (en) 2007-07-12
TW200730202A (en) 2007-08-16
JP2008543729A (ja) 2008-12-04
TWI388345B (zh) 2013-03-11
WO2007001067A2 (en) 2007-01-04

Similar Documents

Publication Publication Date Title
JP5110697B2 (ja) 固形製剤
JP5063370B2 (ja) 湿式造粒製薬の調製方法
JP5148296B2 (ja) アンジオテンシンｉｉ受容体拮抗剤及びカルシウム拮抗剤含有医薬組成物
KR101194453B1 (ko) 동맥 경화 및 고혈압증의 예방 및 치료를 위한 의약
JP2014024874A (ja) 圧縮製剤
PL207252B1 (pl) Kompozycja farmaceutyczna zawierająca antagonistę receptorów angiotensyny II, zastosowanie antagonisty receptorów angiotensyny II oraz zastosowanie kompozycji farmaceutycznej zawierającej antagonistę receptorów angiotensyny II
JP5241510B2 (ja) 固形製剤
JP2010143933A (ja) 眼内血管新生性疾患の予防又は治療のための医薬
JP5241512B2 (ja) 溶出性改善方法
JP4107831B2 (ja) 医薬組成物
WO2009145358A2 (en) Medicament for the prophylaxis or treatment of hypertension
HK1114557B (en) Pharmaceutical preparation containing an angiotensin ii receptor antagonist and a calcium channel blocker
JPWO2008078728A1 (ja) アスコルビン酸含有医薬組成物
HK1054692B (en) Composition containing an angiotensin ii receptor antagonist and a diuretic and its use for the treatment of hypertension

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090616

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090616

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090616

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20111205

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120202

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120522

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120809

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20120824

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20121003

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20121005

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20151019

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Ref document number: 5110697

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250