JP4934432B2 - キナゾリン誘導体およびキナゾリン誘導体の治療への使用 - Google Patents
キナゾリン誘導体およびキナゾリン誘導体の治療への使用 Download PDFInfo
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- JP4934432B2 JP4934432B2 JP2006554220A JP2006554220A JP4934432B2 JP 4934432 B2 JP4934432 B2 JP 4934432B2 JP 2006554220 A JP2006554220 A JP 2006554220A JP 2006554220 A JP2006554220 A JP 2006554220A JP 4934432 B2 JP4934432 B2 JP 4934432B2
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- compound
- fluorophenyl
- phenyl
- chlorophenyl
- tumor
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| US8039637B2 (en) * | 2005-06-23 | 2011-10-18 | Array Biopharma Inc. | Process for preparing benzimidazole compounds |
| AU2007249762A1 (en) * | 2006-05-15 | 2007-11-22 | Senex Biotechnology, Inc | Identification of CDKI pathway inhibitors |
| WO2008124823A1 (en) * | 2007-04-10 | 2008-10-16 | Myriad Genetics, Inc. | Method of treating melanoma |
| CN101120945B (zh) * | 2007-07-30 | 2010-11-24 | 浙江大学 | 8-芳胺基-3H-咪唑[4,5-g]喹唑啉类衍生物的用途 |
| PH12012500097A1 (en) * | 2009-07-21 | 2011-01-27 | Shanghai Inst Organic Chem | Potent small molecule inhibitors of autophagy, and methods of use thereof |
| WO2012006960A1 (en) * | 2010-07-14 | 2012-01-19 | Zhejiang Beta Pharma Inc. | NOVEL FUSED HETEROCYCLIC DERIVATIVES USEFUL AS c-MET TYROSINE KINASE INHIBITORS |
| US20140309224A1 (en) * | 2011-09-13 | 2014-10-16 | Roninson Igor B | TREATMENT OF DISEASES OR DISORDERS CAUSED BY INDUCED NFkB TRANSCRIPTIONAL ACTIVITY |
| CN103086984A (zh) * | 2011-11-03 | 2013-05-08 | 南京大学 | 一类4-苯氨基喹唑啉类衍生物及其制备方法与用途 |
| WO2013135671A1 (en) | 2012-03-13 | 2013-09-19 | Basf Se | Fungicidal pyrimidine compounds |
| CN102659692B (zh) | 2012-05-04 | 2014-04-09 | 郑州泰基鸿诺药物科技有限公司 | 双联厄洛替尼及其制备方法 |
| CN102875570B (zh) * | 2012-10-23 | 2015-11-04 | 浙江大学 | 喹唑啉衍生物及其制备方法和用途 |
| JP6464139B2 (ja) | 2013-03-14 | 2019-02-06 | コンバージーン・リミテッド・ライアビリティ・カンパニーＣｏｎｖｅｒｇｅｎｅ Ｌｌｃ | ブロモドメイン含有タンパク質の阻害のための方法および組成物 |
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| WO2015036059A1 (en) | 2013-09-16 | 2015-03-19 | Basf Se | Fungicidal pyrimidine compounds |
| RU2016112013A (ru) * | 2013-09-19 | 2017-10-24 | Пьер Фабр Медикамент | Производные хиназолина и их применение в качестве ингибиторов днк-метилтрансферазы |
| CN104926798B (zh) * | 2014-03-21 | 2019-06-18 | 江苏豪森药业集团有限公司 | 阿法替尼中间体的高纯度制备方法 |
| CA3006300C (en) | 2015-11-25 | 2024-02-27 | Convergene Llc | Bicyclic bet bromodomain inhibitors and uses thereof |
| JP7191446B2 (ja) * | 2017-01-30 | 2022-12-19 | 塩野義製薬株式会社 | キナゾリン誘導体を含有する固形製剤 |
| EP3897651A4 (en) * | 2018-12-21 | 2022-09-21 | University of Notre Dame du Lac | DISCOVERY OF BD-OXIDASE INHIBITORS FOR THE TREATMENT OF MYCOBACTERIAL DISEASES |
| EP4424379A3 (en) | 2019-04-24 | 2024-10-30 | Convergene Llc | Small molecule bromodomain inhibitors and uses thereof |
| KR102397359B1 (ko) * | 2019-09-30 | 2022-05-11 | 한국화학연구원 | 4-아미노-퀴나졸린 유도체 및 이를 포함하는 항바이러스용 조성물 |
| KR20220132543A (ko) * | 2019-12-27 | 2022-09-30 | 루핀 리미티드 | 치환된 삼환 화합물 |
| TWI807787B (zh) * | 2021-04-19 | 2023-07-01 | 大陸商昆藥集團股份有限公司 | 苯並嘧啶三環衍生物及製備方法和應用 |
| CN116444443B (zh) * | 2023-03-15 | 2025-09-05 | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 一种苯甲酰-喹唑啉酮衍生物及其制备方法与应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01246264A (ja) * | 1988-01-29 | 1989-10-02 | Eli Lilly & Co | キノリン、キナゾリンおよびシンノリン誘導体 |
| JP2000512990A (ja) * | 1996-06-24 | 2000-10-03 | ファイザー・インク | 過増殖性疾患を処置するためのフェニルアミノ置換三環式誘導体 |
| WO2002018373A1 (de) * | 2000-08-26 | 2002-03-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Chinazolin derivate, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CH492395A (de) | 1966-04-26 | 1970-06-30 | Sandoz Ag | Mittel zur Bekämpfung von Pflanzenschädlingen und Verwendung des Mittels |
| US4559157A (en) | 1983-04-21 | 1985-12-17 | Creative Products Resource Associates, Ltd. | Cosmetic applicator useful for skin moisturizing |
| LU84979A1 (fr) | 1983-08-30 | 1985-04-24 | Oreal | Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux |
| US4820508A (en) | 1987-06-23 | 1989-04-11 | Neutrogena Corporation | Skin protective composition |
| US4992478A (en) | 1988-04-04 | 1991-02-12 | Warner-Lambert Company | Antiinflammatory skin moisturizing composition and method of preparing same |
| US5480883A (en) * | 1991-05-10 | 1996-01-02 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
| US5710158A (en) * | 1991-05-10 | 1998-01-20 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
| US6645969B1 (en) * | 1991-05-10 | 2003-11-11 | Aventis Pharmaceuticals Inc. | Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase |
| US5721237A (en) * | 1991-05-10 | 1998-02-24 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties |
| AU661533B2 (en) * | 1992-01-20 | 1995-07-27 | Astrazeneca Ab | Quinazoline derivatives |
| GB9314884D0 (en) * | 1993-07-19 | 1993-09-01 | Zeneca Ltd | Tricyclic derivatives |
| IL112248A0 (en) * | 1994-01-25 | 1995-03-30 | Warner Lambert Co | Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them |
| AU5108196A (en) * | 1995-03-20 | 1996-10-08 | Dr. Karl Thomae Gmbh | Imidazoquinazolines, drugs containing these compounds, their use and process for their preparation |
| MX9707453A (es) * | 1995-03-30 | 1997-12-31 | Pfizer | Derivados de quinazolina. |
| GB9508565D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quiazoline derivative |
| US6046206A (en) * | 1995-06-07 | 2000-04-04 | Cell Pathways, Inc. | Method of treating a patient having a precancerous lesions with amide quinazoline derivatives |
| GB9603095D0 (en) * | 1996-02-14 | 1996-04-10 | Zeneca Ltd | Quinazoline derivatives |
| GB9613021D0 (en) * | 1996-06-21 | 1996-08-28 | Pharmacia Spa | Bicyclic 4-aralkylaminopyrimidine derivatives as tyrosine kinase inhibitors |
| HUP9900790A3 (en) | 1996-08-30 | 2001-11-28 | Kyowa Hakko Kogyo Kk | Imidazoquinazoline derivatives |
| US6258820B1 (en) * | 1999-03-19 | 2001-07-10 | Parker Hughes Institute | Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines |
| ES2267748T3 (es) | 2000-04-07 | 2007-03-16 | Astrazeneca Ab | Compuestos de quinazolina. |
| US6653305B2 (en) * | 2000-08-26 | 2003-11-25 | Boehringer Ingelheim Pharma Kg | Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them |
-
2005
- 2005-02-17 JP JP2006554220A patent/JP4934432B2/ja not_active Expired - Fee Related
- 2005-02-17 CN CN2005800117828A patent/CN1956966B/zh not_active Expired - Fee Related
- 2005-02-17 ES ES05723255.5T patent/ES2554330T3/es not_active Expired - Lifetime
- 2005-02-17 BR BRPI0507903-9A patent/BRPI0507903A/pt not_active IP Right Cessation
- 2005-02-17 KR KR1020067019158A patent/KR100942865B1/ko not_active Expired - Fee Related
- 2005-02-17 EP EP13173085.5A patent/EP2650286A1/en not_active Withdrawn
- 2005-02-17 CA CA2557433A patent/CA2557433C/en not_active Expired - Fee Related
- 2005-02-17 US US11/059,376 patent/US7388014B2/en not_active Expired - Lifetime
- 2005-02-17 MX MXPA06009475A patent/MXPA06009475A/es active IP Right Grant
- 2005-02-17 AU AU2005214373A patent/AU2005214373B2/en not_active Ceased
- 2005-02-17 WO PCT/US2005/005151 patent/WO2005080352A2/en not_active Ceased
- 2005-02-17 EP EP05723255.5A patent/EP1720841B1/en not_active Expired - Lifetime
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2008
- 2008-06-16 US US12/213,182 patent/US8404698B2/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01246264A (ja) * | 1988-01-29 | 1989-10-02 | Eli Lilly & Co | キノリン、キナゾリンおよびシンノリン誘導体 |
| JP2000512990A (ja) * | 1996-06-24 | 2000-10-03 | ファイザー・インク | 過増殖性疾患を処置するためのフェニルアミノ置換三環式誘導体 |
| WO2002018373A1 (de) * | 2000-08-26 | 2002-03-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Chinazolin derivate, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung |
Also Published As
| Publication number | Publication date |
|---|---|
| US8404698B2 (en) | 2013-03-26 |
| EP1720841B1 (en) | 2015-11-04 |
| BRPI0507903A (pt) | 2007-07-10 |
| CN1956966B (zh) | 2012-04-18 |
| KR20070028340A (ko) | 2007-03-12 |
| CA2557433C (en) | 2013-05-14 |
| US20090030021A1 (en) | 2009-01-29 |
| EP1720841A2 (en) | 2006-11-15 |
| WO2005080352A3 (en) | 2006-02-16 |
| JP2007523177A (ja) | 2007-08-16 |
| US20050187231A1 (en) | 2005-08-25 |
| MXPA06009475A (es) | 2007-05-15 |
| EP2650286A1 (en) | 2013-10-16 |
| CA2557433A1 (en) | 2005-09-01 |
| KR100942865B1 (ko) | 2010-02-17 |
| AU2005214373A1 (en) | 2005-09-01 |
| US7388014B2 (en) | 2008-06-17 |
| WO2005080352A2 (en) | 2005-09-01 |
| AU2005214373B2 (en) | 2011-07-28 |
| CN1956966A (zh) | 2007-05-02 |
| ES2554330T3 (es) | 2015-12-18 |
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