JP4855577B2 - ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 - Google Patents
ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 Download PDFInfo
- Publication number
- JP4855577B2 JP4855577B2 JP2000552151A JP2000552151A JP4855577B2 JP 4855577 B2 JP4855577 B2 JP 4855577B2 JP 2000552151 A JP2000552151 A JP 2000552151A JP 2000552151 A JP2000552151 A JP 2000552151A JP 4855577 B2 JP4855577 B2 JP 4855577B2
- Authority
- JP
- Japan
- Prior art keywords
- strap
- protein
- prostate
- cancer
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8752098P | 1998-06-01 | 1998-06-01 | |
| US60/087,520 | 1998-06-01 | ||
| US9118398P | 1998-06-30 | 1998-06-30 | |
| US60/091,183 | 1998-06-30 | ||
| PCT/US1999/012157 WO1999062941A2 (en) | 1998-06-01 | 1999-06-01 | Serpentine transmembrane antigens expressed in human cancers and uses thereof |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008278478A Division JP4871341B2 (ja) | 1998-06-01 | 2008-10-29 | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 |
| JP2011188088A Division JP5683414B2 (ja) | 1998-06-01 | 2011-08-31 | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002517184A JP2002517184A (ja) | 2002-06-18 |
| JP2002517184A5 JP2002517184A5 (cg-RX-API-DMAC7.html) | 2005-11-17 |
| JP4855577B2 true JP4855577B2 (ja) | 2012-01-18 |
Family
ID=26777066
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000552151A Expired - Lifetime JP4855577B2 (ja) | 1998-06-01 | 1999-06-01 | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 |
| JP2008278478A Expired - Lifetime JP4871341B2 (ja) | 1998-06-01 | 2008-10-29 | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 |
| JP2011188088A Expired - Lifetime JP5683414B2 (ja) | 1998-06-01 | 2011-08-31 | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 |
| JP2014169206A Pending JP2014239695A (ja) | 1998-06-01 | 2014-08-22 | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 |
| JP2016229709A Expired - Lifetime JP6371362B2 (ja) | 1998-06-01 | 2016-11-28 | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008278478A Expired - Lifetime JP4871341B2 (ja) | 1998-06-01 | 2008-10-29 | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 |
| JP2011188088A Expired - Lifetime JP5683414B2 (ja) | 1998-06-01 | 2011-08-31 | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 |
| JP2014169206A Pending JP2014239695A (ja) | 1998-06-01 | 2014-08-22 | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 |
| JP2016229709A Expired - Lifetime JP6371362B2 (ja) | 1998-06-01 | 2016-11-28 | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (10) | US6329503B1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP1086223B1 (cg-RX-API-DMAC7.html) |
| JP (5) | JP4855577B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE437947T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU757698C (cg-RX-API-DMAC7.html) |
| CA (1) | CA2328989C (cg-RX-API-DMAC7.html) |
| CY (1) | CY1109509T1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE69941187D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1086223T3 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2329851T3 (cg-RX-API-DMAC7.html) |
| IL (2) | IL139699A0 (cg-RX-API-DMAC7.html) |
| PT (1) | PT1086223E (cg-RX-API-DMAC7.html) |
| WO (1) | WO1999062941A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6136311A (en) | 1996-05-06 | 2000-10-24 | Cornell Research Foundation, Inc. | Treatment and diagnosis of cancer |
| US20020187472A1 (en) * | 2001-03-09 | 2002-12-12 | Preeti Lal | Steap-related protein |
| US20060052321A1 (en) | 2002-04-05 | 2006-03-09 | Raitano Arthur B | Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer |
| US20030149531A1 (en) * | 2000-12-06 | 2003-08-07 | Hubert Rene S. | Serpentine transmembrane antigens expressed in human cancers and uses thereof |
| ES2329851T3 (es) | 1998-06-01 | 2009-12-01 | Agensys, Inc. | Nuevos antigenos transmembranables expresados en canceres humano y utilizacion de los mismos. |
| US6833438B1 (en) | 1999-06-01 | 2004-12-21 | Agensys, Inc. | Serpentine transmembrane antigens expressed in human cancers and uses thereof |
| US20040048798A1 (en) * | 1999-06-01 | 2004-03-11 | Raitano Arthur B. | Nucleic acid and corresponding protein entitle 98P4B6 useful in treatment and detection of cancer |
| US20040141975A1 (en) * | 1998-06-01 | 2004-07-22 | Raitano Arthur B. | Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer |
| US6902892B1 (en) | 1998-10-19 | 2005-06-07 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating prostate cancer |
| AU5416700A (en) * | 1999-05-20 | 2000-12-12 | Fahri Saatcioglu | Differentially expressed genes in prostate cancer |
| DK1244705T3 (da) * | 1999-12-06 | 2010-05-31 | Agensys Inc | Serpentintransmembrane antigener udtryk i human prostatacancere og anvendelser deraf |
| EP1257585A2 (en) * | 2000-02-10 | 2002-11-20 | Basf Aktiengesellschaft | Antibodies that bind human interleukin-18 and methods of making and using |
| US7611892B2 (en) * | 2000-03-24 | 2009-11-03 | President And Fellows Of Harvard College | Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
| AU2001249411B2 (en) * | 2000-03-24 | 2007-02-15 | Fahri Saatcioglu | Novel prostate-specific or testis-specific nucleic acid molecules, polypeptides,and diagnostic and therapeutic methods |
| US7189565B2 (en) | 2001-03-23 | 2007-03-13 | Fahri Saatcioglu | Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
| CN101555283B (zh) | 2001-01-17 | 2012-03-21 | 生物权威国际有限公司 | 针对非功能性p2x7受体的抗体及其在癌症和其它病情的诊断和治疗中的用途 |
| US20030194798A1 (en) | 2001-05-24 | 2003-10-16 | Surber Mark W. | Minicell compositions and methods |
| ES2537074T3 (es) * | 2001-09-06 | 2015-06-02 | Agensys, Inc. | Ácido nucleico y proteína correspondiente denominados STEAP-1 útiles en el tratamiento y la detección de cáncer |
| US7494646B2 (en) * | 2001-09-06 | 2009-02-24 | Agensys, Inc. | Antibodies and molecules derived therefrom that bind to STEAP-1 proteins |
| AU2002360670A1 (en) * | 2001-12-19 | 2003-07-09 | Wilk Patent Development Corporation | Method and related composition employing nanostructures |
| ES2541351T3 (es) | 2002-02-25 | 2015-07-17 | Vaxiion Therapeutics, Llc | Composiciones de minicélulas y procedimientos |
| AU2003256912A1 (en) * | 2002-08-16 | 2004-03-03 | Yeda Research And Development Co. Ltd. | Tumor associated antigen, peptides thereof, and use of same as anti-tumor vaccines |
| JP5840351B2 (ja) * | 2002-09-06 | 2016-01-06 | アジェンシス,インコーポレイテッド | 癌の処置および検出において有用な98p4b6と称される、核酸および対応タンパク質 |
| KR101438983B1 (ko) | 2003-11-06 | 2014-09-05 | 시애틀 지네틱스, 인크. | 리간드에 접합될 수 있는 모노메틸발린 화합물 |
| KR101215179B1 (ko) | 2004-04-22 | 2012-12-24 | 어젠시스 인코포레이티드 | Steap-1 단백질과 결합하는 항체 및 그로부터 유래된분자 |
| US8765164B2 (en) * | 2005-10-21 | 2014-07-01 | Kenneth W. Carpenter | Poly(ester urea) polymers and methods of use |
| JP2009531324A (ja) | 2006-03-20 | 2009-09-03 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 癌標的化のための操作された抗前立腺幹細胞抗原(psca)抗体 |
| US20100036101A1 (en) * | 2006-10-10 | 2010-02-11 | Angus Gidley-Baird | Antibodies against non functional p2x7 receptor |
| WO2008043145A1 (en) * | 2006-10-10 | 2008-04-17 | Biosceptre International Limited | Hybridomas producing antibodies against non functional p2x7 receptor |
| DK2502938T3 (en) | 2006-10-27 | 2015-04-20 | Genentech Inc | Antibodies and immunoconjugates and uses thereof |
| JP5469600B2 (ja) | 2007-07-16 | 2014-04-16 | ジェネンテック, インコーポレイテッド | 抗CD79b抗体及びイムノコンジュゲートとその使用方法 |
| EP2176295B1 (en) | 2007-07-16 | 2014-11-19 | Genentech, Inc. | Humanized anti-cd79b antibodies and immunoconjugates and methods of use |
| SI2187965T1 (sl) | 2007-08-17 | 2020-03-31 | Purdue Research Foundation Office Of Technology Commercialization | Konjugati vezalca ligand-veznika PSMA in metode za uporabo |
| CA2698343C (en) | 2007-09-04 | 2018-06-12 | The Regents Of The University Of California | High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection |
| AU2008299594B2 (en) | 2007-09-14 | 2013-10-03 | Biosceptre International Limited | Purinergic (P2X) receptors in extra-cellular body fluid |
| NZ583894A (en) | 2007-09-14 | 2013-01-25 | Biosceptre Int Ltd | Antibodies that bind to a non atp binding p2x7 receptor |
| JP5951929B2 (ja) * | 2007-10-03 | 2016-07-13 | コーネル ユニヴァーシティー | Psma抗体を用いる増殖性障害の治療 |
| ES2643239T3 (es) | 2008-01-31 | 2017-11-21 | Genentech, Inc. | Anticuerpos anti-CD79b e inmunoconjugados y métodos de uso |
| AU2009266430B2 (en) | 2008-07-04 | 2014-08-14 | Biosceptre International Limited | Anti- P2X7 peptides and epitopes |
| EP2398504B1 (en) | 2009-02-17 | 2018-11-28 | Cornell Research Foundation, Inc. | Methods and kits for diagnosis of cancer and prediction of therapeutic value |
| ES2904911T3 (es) | 2009-08-20 | 2022-04-06 | Biosceptre Aust Pty Ltd | Anticuerpos anti-receptor P2X7 y fragmentos de los mismos |
| EP2506876B1 (en) | 2009-12-02 | 2016-10-12 | Imaginab, Inc. | J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use |
| WO2011075789A1 (en) | 2009-12-24 | 2011-06-30 | Biosceptre International Limited | Antibodies to non-functional oligomeric p2x7 receptors |
| US9951324B2 (en) | 2010-02-25 | 2018-04-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
| KR20130098165A (ko) | 2010-06-03 | 2013-09-04 | 제넨테크, 인크. | 항체 및 면역접합체의 이뮤노-pet 영상화 및 그의 용도 |
| US9562094B2 (en) | 2010-09-10 | 2017-02-07 | Biosceptre (Aust) Pty Ltd | Companion animal treatments |
| WO2012057765A1 (en) | 2010-10-28 | 2012-05-03 | The Board Of Regents Of The University Of Texas System | Recombinant anti-cd19 monoclonal antibodies |
| AU2015261742B2 (en) * | 2010-11-12 | 2017-10-26 | Inovio Pharmaceuticals, Inc. | Consensus prostate antigens nucleic acid molecule encoding the same and vaccine and uses comprising the same |
| KR101939150B1 (ko) * | 2010-11-12 | 2019-01-17 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 공통 전립선 항원, 이것을 암호화하는 핵산 분자, 그리고 이것을 포함하는 백신 및 용도 |
| DK2675474T3 (en) | 2011-02-15 | 2019-04-23 | Vaxiion Therapeutics Llc | THERAPEUTIC COMPOSITIONS AND PROCEDURES FOR TARGETED ADMINISTRATION OF BIOACTIVE MOLECULES BY BACK-TERIAL MINICLES BASED ON ANTIBODY AND FC-CONTAINING TAR-GETING MOLECULES |
| EP2726095B1 (en) | 2011-07-01 | 2018-06-06 | Biosceptre (Aust) Pty Ltd | Combination therapy |
| CN104067127A (zh) | 2011-11-29 | 2014-09-24 | 霍夫曼-拉罗奇有限公司 | 用于前列腺癌分析的组合物和方法 |
| KR102318999B1 (ko) | 2012-11-15 | 2021-10-29 | 엔도사이트, 인코포레이티드 | Psma 발현 세포에 의해 야기되는 질병을 치료하기 위한 컨쥬게이트 |
| AU2014255381A1 (en) | 2013-04-17 | 2015-10-08 | Pfizer Inc. | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
| KR101782623B1 (ko) | 2013-07-10 | 2017-09-28 | 서울대학교산학협력단 | 복합 막횡단 단백질의 세포막외 펩타이드 항원 및 그의 용도 |
| GEP20237497B (en) | 2013-10-18 | 2023-04-10 | Deutsches Krebsforsch | Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer |
| US20160287731A1 (en) | 2013-11-14 | 2016-10-06 | Endocyte, Inc. | Compounds for Positron Emission Tomography |
| EP3262071B8 (en) | 2014-09-23 | 2022-05-18 | F. Hoffmann-La Roche AG | Method of using anti-cd79b immunoconjugates |
| US10188759B2 (en) | 2015-01-07 | 2019-01-29 | Endocyte, Inc. | Conjugates for imaging |
| WO2016205176A1 (en) | 2015-06-15 | 2016-12-22 | Genentech, Inc. | Antibodies and immunoconjugates |
| AU2016304764C1 (en) | 2015-08-07 | 2023-06-01 | Imaginab, Inc. | Antigen binding constructs to target molecules |
| WO2017106806A1 (en) | 2015-12-18 | 2017-06-22 | Federica Cavallo | COMPOSITIONS AND METHODS RELATED TO xCT PEPTIDES |
| US10772972B2 (en) * | 2016-09-23 | 2020-09-15 | Regeneron Pharmaceuticals, Inc. | Anti-STEAP2 antibody drug conjugates, and compositions and uses thereof |
| JP7105235B2 (ja) | 2016-12-01 | 2022-07-22 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 免疫petイメージングのための放射性標識された抗pd-l1抗体 |
| US11266745B2 (en) | 2017-02-08 | 2022-03-08 | Imaginab, Inc. | Extension sequences for diabodies |
| MX2019011769A (es) | 2017-04-03 | 2019-11-07 | Hoffmann La Roche | Anticuerpos que se unen a steap-1. |
| EP3618869A4 (en) | 2017-05-01 | 2021-01-20 | Agilvax, Inc. | COMPOSITIONS AND PROCEDURES RELATED TO XCT ANTIBODIES |
| JP7348844B2 (ja) | 2017-06-07 | 2023-09-21 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 内部移行酵素のための組成物および方法 |
| JP2021522193A (ja) | 2018-04-17 | 2021-08-30 | エンドサイト・インコーポレイテッドEndocyte, Inc. | 癌を治療する方法 |
| US12252544B2 (en) | 2018-05-17 | 2025-03-18 | Regeneron Pharmaceuticals, Inc. | Anti-CD63 antibodies, conjugates, and uses thereof |
| MY208638A (en) | 2018-07-02 | 2025-05-21 | Amgen Inc | Anti-steap1 antigen-binding protein |
| EP3823993A1 (en) * | 2018-07-18 | 2021-05-26 | Amgen Inc. | Chimeric receptors to steap1 and methods of use thereof |
| US12473265B2 (en) | 2019-05-20 | 2025-11-18 | Endocyte, Inc. | Methods for preparing PSMA conjugates |
Family Cites Families (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| US5851764A (en) * | 1990-10-25 | 1998-12-22 | The Trustees Of Columbia University In The City Of New York | Human prostate tumor inducing gene-1 and uses thereof |
| US5489525A (en) | 1992-10-08 | 1996-02-06 | The United States Of America As Represented By The Department Of Health And Human Services | Monoclonal antibodies to prostate cells |
| EP0679716A4 (en) | 1993-11-12 | 1999-06-09 | Kenichi Matsubara | GENE SIGNATURE. |
| EP0914155B1 (en) * | 1996-03-25 | 2006-02-22 | Medarex, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate specific membrane antigen |
| US5859045A (en) | 1996-05-08 | 1999-01-12 | Novo Nordisk A/S Novo Alle | Crystalline -! 3R 4R-trans-7 methoxy 2,2-dimethyl1-3-phenyl 1-4 4-12 pyrrolidin-1 -Y1!ethoxyl 1!chromane hydrogen fumarate |
| DE69734249T2 (de) * | 1996-07-15 | 2006-07-13 | Mayo Foundation For Medical Education And Research, Rochester | Verfahren zur detektion der hk2 polypeptide |
| US5824504A (en) * | 1996-09-26 | 1998-10-20 | Elshourbagy; Nabil A. | Human 7-transmembrane receptor and DNA |
| DE19641560A1 (de) * | 1996-10-09 | 1998-04-16 | Boehringer Mannheim Gmbh | Monoklonale Antikörper gegen einen Komplex aus humanem ACT und einer Serinprotease |
| ES2290964T3 (es) | 1996-10-15 | 2008-02-16 | The Regents Of The University Of California | Modelos animales de la evolucion del cancer de prostata humano. |
| WO1998018489A1 (en) | 1996-10-30 | 1998-05-07 | The Uab Research Foundation | Enhancement of tumor cell chemosensitivity and radiosensitivity using single chain intracellular antibodies |
| EP2305027B1 (en) | 1996-12-03 | 2014-07-02 | Amgen Fremont Inc. | Transgenic mammals having human Ig loci including plural VH and Vkappa regions and antibodies produced therefrom |
| CN1195851C (zh) | 1997-02-25 | 2005-04-06 | 科里克萨有限公司 | 用于前列腺癌免疫疗法的化合物及其用途 |
| DK0972201T3 (da) | 1997-02-25 | 2006-01-02 | Corixa Corp | Forbindelser til immundiagnosticering af prostatacancer og fremgangsmåder til anvendelse heraf |
| US6800746B2 (en) | 1997-02-25 | 2004-10-05 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
| WO2000035937A1 (en) | 1998-12-17 | 2000-06-22 | Human Genome Sciences, Inc. | 47 human secreted proteins |
| JP2002516572A (ja) * | 1997-05-23 | 2002-06-04 | バイオジェン,インコーポレイテッド | 組織の再生の調節 |
| ATE338117T1 (de) | 1997-08-01 | 2006-09-15 | Serono Genetics Inst Sa | 5' ests für proteine, die nicht gewebespezifisch sind |
| AU8555198A (en) | 1997-08-01 | 1999-02-22 | Genset | 5' ests for secreted proteins expressed in prostate |
| JPH11164691A (ja) | 1997-10-03 | 1999-06-22 | Rikagaku Kenkyusho | 胚盤胞cDNA |
| US20030060612A1 (en) | 1997-10-28 | 2003-03-27 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| US6255049B1 (en) * | 1998-02-27 | 2001-07-03 | The Trustees Of Columbia University In The City Of New York | Detection of metastatic cancer cells using PCTA-1 |
| US20030064397A1 (en) | 1998-05-22 | 2003-04-03 | Incyte Genomics, Inc. | Transmembrane protein differentially expressed in prostate and lung tumors |
| US6048970A (en) | 1998-05-22 | 2000-04-11 | Incyte Pharmaceuticals, Inc. | Prostate growth-associated membrane proteins |
| ES2329851T3 (es) | 1998-06-01 | 2009-12-01 | Agensys, Inc. | Nuevos antigenos transmembranables expresados en canceres humano y utilizacion de los mismos. |
| KR20010083111A (ko) | 1998-07-14 | 2001-08-31 | 길리스 스티브 | 전립선암의 치료 및 진단을 위한 조성물 및 방법 |
| WO2000077021A1 (en) | 1999-06-11 | 2000-12-21 | Human Genome Sciences, Inc. | 48 human secreted proteins |
| CN1308347C (zh) | 1999-04-28 | 2007-04-04 | 德克萨斯大学董事会 | 用于通过选择性抑制vegf来治疗癌症的组合物和方法 |
| JP2003527089A (ja) | 1999-08-17 | 2003-09-16 | インサイト・ゲノミックス・インコーポレイテッド | 膜関連タンパク質 |
| GB2354821A (en) | 1999-09-29 | 2001-04-04 | Dine O Quick | Threshold crossing counter |
| AU7994200A (en) | 1999-10-04 | 2001-05-10 | Corixa Corporation | Compositions and methods for therapy and diagnosis of prostate cancer |
| UA74798C2 (uk) | 1999-10-06 | 2006-02-15 | Байоджен Айдек Ма Інк. | Спосіб лікування раку у ссавця за допомогою поліпептиду, що протидіє взаємодії april з його рецепторами |
| WO2001034802A2 (en) | 1999-11-12 | 2001-05-17 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
| DK1244705T3 (da) | 1999-12-06 | 2010-05-31 | Agensys Inc | Serpentintransmembrane antigener udtryk i human prostatacancere og anvendelser deraf |
| AU3447401A (en) | 2000-01-14 | 2001-07-24 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
| AU2001234944A1 (en) | 2000-02-03 | 2001-08-14 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| US20020081590A1 (en) | 2000-02-04 | 2002-06-27 | Aeomica, Inc. | Methods and apparatus for predicting, confirming, and displaying functional information derived from genomic sequence |
| WO2001060860A2 (en) | 2000-02-17 | 2001-08-23 | Millennium Predictive Medicine, Inc. | Genes differentially expressed in human prostate cancer and their use |
| AU2001249411B2 (en) | 2000-03-24 | 2007-02-15 | Fahri Saatcioglu | Novel prostate-specific or testis-specific nucleic acid molecules, polypeptides,and diagnostic and therapeutic methods |
| WO2001073032A2 (en) | 2000-03-27 | 2001-10-04 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
| US6436703B1 (en) | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| WO2001094629A2 (en) | 2000-06-05 | 2001-12-13 | Avalon Pharmaceuticals | Cancer gene determination and therapeutic screening using signature gene sets |
| CA2412223A1 (en) | 2000-06-09 | 2001-12-20 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| JP2004508019A (ja) | 2000-07-28 | 2004-03-18 | コンピュジェン インコーポレイテッド | トランスクリプトームの中に場所を占めるrna転写物及びスプライス変異体を検出するためのオリゴヌクレオチドライブラリー |
| EP1445318A2 (en) | 2000-08-24 | 2004-08-11 | Genetech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| WO2002030268A2 (en) | 2000-10-13 | 2002-04-18 | Eos Biotechnology, Inc. | Methods of diagnosis of prostate cancer, compositions and methods of screening for modulators of prostate cancer |
| CA2429343A1 (en) | 2000-11-17 | 2002-08-01 | Hyseq, Inc. | Nucleic acids and polypeptides |
| WO2002057303A2 (en) | 2001-01-12 | 2002-07-25 | Hybrigenics | Protein-protein interactions between shigella flexneri polypeptides and mammalian polypeptides |
| EP1390390A4 (en) | 2001-03-21 | 2009-07-08 | Human Genome Sciences Inc | HUMAN SECRETED PROTEINS |
| WO2003009814A2 (en) | 2001-07-25 | 2003-02-06 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer |
| US7494646B2 (en) | 2001-09-06 | 2009-02-24 | Agensys, Inc. | Antibodies and molecules derived therefrom that bind to STEAP-1 proteins |
| ES2537074T3 (es) | 2001-09-06 | 2015-06-02 | Agensys, Inc. | Ácido nucleico y proteína correspondiente denominados STEAP-1 útiles en el tratamiento y la detección de cáncer |
| EP1308459A3 (en) | 2001-11-05 | 2003-07-09 | Research Association for Biotechnology | Full-length cDNA sequences |
| US6918525B2 (en) * | 2003-05-23 | 2005-07-19 | Worktools, Inc. | Spring energized desktop stapler |
| KR101215179B1 (ko) * | 2004-04-22 | 2012-12-24 | 어젠시스 인코포레이티드 | Steap-1 단백질과 결합하는 항체 및 그로부터 유래된분자 |
| CN104447992A (zh) | 2004-09-23 | 2015-03-25 | 健泰科生物技术公司 | 半胱氨酸改造的抗体和偶联物 |
| US7056186B1 (en) * | 2005-04-06 | 2006-06-06 | Weyenberg Karey M | Cleavage-enhancing foundation garment |
-
1999
- 1999-06-01 ES ES99955273T patent/ES2329851T3/es not_active Expired - Lifetime
- 1999-06-01 JP JP2000552151A patent/JP4855577B2/ja not_active Expired - Lifetime
- 1999-06-01 EP EP99955273A patent/EP1086223B1/en not_active Expired - Lifetime
- 1999-06-01 US US09/323,873 patent/US6329503B1/en not_active Expired - Lifetime
- 1999-06-01 IL IL13969999A patent/IL139699A0/xx not_active IP Right Cessation
- 1999-06-01 AU AU43262/99A patent/AU757698C/en not_active Expired
- 1999-06-01 WO PCT/US1999/012157 patent/WO1999062941A2/en not_active Ceased
- 1999-06-01 ES ES09002996.8T patent/ES2629442T3/es not_active Expired - Lifetime
- 1999-06-01 EP EP09002996.8A patent/EP2080802B1/en not_active Expired - Lifetime
- 1999-06-01 DE DE69941187T patent/DE69941187D1/de not_active Expired - Lifetime
- 1999-06-01 PT PT99955273T patent/PT1086223E/pt unknown
- 1999-06-01 AT AT99955273T patent/ATE437947T1/de active
- 1999-06-01 DK DK99955273T patent/DK1086223T3/da active
- 1999-06-01 CA CA2328989A patent/CA2328989C/en not_active Expired - Lifetime
-
2001
- 2001-12-06 US US10/010,667 patent/US6887975B2/en not_active Expired - Lifetime
- 2001-12-06 US US10/011,095 patent/US7053186B2/en not_active Expired - Lifetime
-
2003
- 2003-12-31 US US10/750,262 patent/US7166714B2/en not_active Expired - Lifetime
-
2004
- 2004-06-01 US US10/858,887 patent/US7575749B2/en not_active Expired - Lifetime
-
2005
- 2005-09-12 US US11/225,661 patent/US7642054B2/en not_active Expired - Lifetime
-
2006
- 2006-10-12 US US11/580,538 patent/US7611904B2/en not_active Expired - Fee Related
-
2008
- 2008-10-29 JP JP2008278478A patent/JP4871341B2/ja not_active Expired - Lifetime
-
2009
- 2009-10-07 US US12/575,092 patent/US7928201B2/en not_active Expired - Fee Related
- 2009-10-07 US US12/575,164 patent/US7968307B2/en not_active Expired - Fee Related
- 2009-10-15 CY CY20091101080T patent/CY1109509T1/el unknown
-
2010
- 2010-01-26 IL IL203524A patent/IL203524A/en not_active IP Right Cessation
-
2011
- 2011-06-13 US US13/134,650 patent/US8414898B2/en not_active Expired - Fee Related
- 2011-08-31 JP JP2011188088A patent/JP5683414B2/ja not_active Expired - Lifetime
-
2014
- 2014-08-22 JP JP2014169206A patent/JP2014239695A/ja active Pending
-
2016
- 2016-11-28 JP JP2016229709A patent/JP6371362B2/ja not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6371362B2 (ja) | ヒト癌で発現される新規蛇行性膜貫通抗原およびその使用 | |
| US7455991B2 (en) | Serpentine transmembrane antigens expressed in human cancers and uses thereof | |
| AU2003204605B2 (en) | Novel serpentine transmembrane antigens expressed in human cancers and uses thereof | |
| AU2006200459C1 (en) | Novel serpentine transmembrane antigens expressed in human cancers and uses thereof | |
| HK1133672A (en) | Novel serpentine transmembrane antigens expressed in human cancers and uses thereof | |
| HK1133672B (en) | Novel serpentine transmembrane antigens expressed in human cancers and uses thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20040426 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20040426 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20070620 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20070918 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20070926 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20071019 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20071026 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20071120 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20071128 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20071220 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20080702 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20081029 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20081219 |
|
| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20090105 |
|
| A912 | Re-examination (zenchi) completed and case transferred to appeal board |
Free format text: JAPANESE INTERMEDIATE CODE: A912 Effective date: 20090313 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20091002 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20110831 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20111027 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20141104 Year of fee payment: 3 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 4855577 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| EXPY | Cancellation because of completion of term |