JP4808316B2 - 多能性造血幹細胞の動員を刺激するためのヒト成長ホルモン - Google Patents
多能性造血幹細胞の動員を刺激するためのヒト成長ホルモン Download PDFInfo
- Publication number
- JP4808316B2 JP4808316B2 JP2000592015A JP2000592015A JP4808316B2 JP 4808316 B2 JP4808316 B2 JP 4808316B2 JP 2000592015 A JP2000592015 A JP 2000592015A JP 2000592015 A JP2000592015 A JP 2000592015A JP 4808316 B2 JP4808316 B2 JP 4808316B2
- Authority
- JP
- Japan
- Prior art keywords
- growth hormone
- cells
- administered
- csf
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98124834A EP1016413A1 (en) | 1998-12-30 | 1998-12-30 | Human growth hormone to stimulate mobilization of pluripotent hematopoietic stem cells |
| EP98124834.7 | 1998-12-30 | ||
| PCT/EP1999/010470 WO2000040260A1 (en) | 1998-12-30 | 1999-12-30 | Human growth hormone to stimulate mobilization of pluripotent hematopoietic stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002534393A JP2002534393A (ja) | 2002-10-15 |
| JP2002534393A5 JP2002534393A5 (https=) | 2010-11-18 |
| JP4808316B2 true JP4808316B2 (ja) | 2011-11-02 |
Family
ID=8233268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000592015A Expired - Fee Related JP4808316B2 (ja) | 1998-12-30 | 1999-12-30 | 多能性造血幹細胞の動員を刺激するためのヒト成長ホルモン |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20060029581A1 (https=) |
| EP (3) | EP1016413A1 (https=) |
| JP (1) | JP4808316B2 (https=) |
| AT (1) | ATE342064T1 (https=) |
| AU (2) | AU772222B2 (https=) |
| BR (1) | BR9916726A (https=) |
| CA (1) | CA2354194A1 (https=) |
| CY (1) | CY1107603T1 (https=) |
| DE (1) | DE69933581T2 (https=) |
| DK (1) | DK1140149T3 (https=) |
| ES (1) | ES2275359T3 (https=) |
| IL (2) | IL143994A0 (https=) |
| PT (1) | PT1140149E (https=) |
| SI (1) | SI1140149T1 (https=) |
| WO (1) | WO2000040260A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003535144A (ja) * | 2000-06-07 | 2003-11-25 | アプライド・リサーチ・システムズ・エイアールエス・ホールディング・ナムローゼ・フェンノートシャップ | 多能性造血幹細胞の流動を刺激するヒト成長ホルモン |
| CA2417356A1 (en) | 2000-08-01 | 2002-02-07 | Yissum Research Development Company | Directed differentiation of embryonic cells |
| ES2380009T3 (es) * | 2001-07-31 | 2012-05-07 | Genzyme Global S.A.R.L. | Métodos para movilizar las células madre/progenitoras |
| CA2540529C (en) * | 2003-10-03 | 2012-03-13 | Vib Vzw | Means and methods for the recruitment and identification of stem cells |
| JP2005289837A (ja) * | 2004-03-31 | 2005-10-20 | Juntendo | 骨髄細胞誘導剤の製造方法及び製造装置 |
| US7816320B2 (en) * | 2004-12-22 | 2010-10-19 | Ambrx, Inc. | Formulations of human growth hormone comprising a non-naturally encoded amino acid at position 35 |
| JP2013515081A (ja) * | 2009-12-21 | 2013-05-02 | アンブルックス,インコーポレイテッド | 修飾されているブタのソマトトロピンポリペプチドおよびそれらの使用 |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07101877A (ja) * | 1993-10-04 | 1995-04-18 | Mitsui Toatsu Chem Inc | 血小板減少症治療剤 |
| JPH07505527A (ja) * | 1992-03-30 | 1995-06-22 | シェリング・コーポレーション | ヒト樹状細胞のインビトロ発生およびそれらの用途 |
| JPH0892001A (ja) * | 1994-09-26 | 1996-04-09 | Asahi Medical Co Ltd | 細胞集団の保存方法 |
| WO1997003684A1 (en) * | 1995-07-21 | 1997-02-06 | THE GOVERNMENT OF THE UNITED STATES, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Method of decreasing radiation or radio-mimetic chemotherapy for hematopoietic pluripotent cell engraftment |
| JPH09506245A (ja) * | 1993-10-06 | 1997-06-24 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイテッド | 幹細胞増殖因子 |
| WO1997026326A1 (en) * | 1996-01-16 | 1997-07-24 | Depuy Orthopaedics, Inc. | Isolation of precursor cells from hematopoietic and non-hematopoietic tissues and their use |
| JPH10206423A (ja) * | 1996-11-20 | 1998-08-07 | Toa Medical Electronics Co Ltd | 幼若白血球の分類計数法 |
| JPH10295369A (ja) * | 1997-02-26 | 1998-11-10 | Japan Tobacco Inc | 造血幹細胞の製造方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5649904A (en) * | 1988-10-07 | 1997-07-22 | Sandoz Ltd. | Method of treating cancer with a fully myeloablative regimen of chemotherapy, radiation or both |
| US5199942A (en) * | 1991-06-07 | 1993-04-06 | Immunex Corporation | Method for improving autologous transplantation |
| DE69430059T2 (de) * | 1993-06-15 | 2002-11-14 | British Biotech Pharmaceuticals Ltd., Cowley | Freisetzung und Mobilisierung hämatopoietischer Zellen |
| SE9804064D0 (sv) * | 1998-11-25 | 1998-11-25 | A & Science Invest Ab | Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells |
| DE69919969T2 (de) * | 1998-12-17 | 2005-09-29 | Applied Research Systems Ars Holding N.V. | Humanes Wachstumshormon zur Stimulierung der Hämatopoese und der Immunrekonstitution nach hämatopoetischer Stammzelltransplantation beim Menschen |
| JP2003535144A (ja) * | 2000-06-07 | 2003-11-25 | アプライド・リサーチ・システムズ・エイアールエス・ホールディング・ナムローゼ・フェンノートシャップ | 多能性造血幹細胞の流動を刺激するヒト成長ホルモン |
| US7220407B2 (en) * | 2003-10-27 | 2007-05-22 | Amgen Inc. | G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction |
-
1998
- 1998-12-30 EP EP98124834A patent/EP1016413A1/en not_active Withdrawn
-
1999
- 1999-12-30 WO PCT/EP1999/010470 patent/WO2000040260A1/en not_active Ceased
- 1999-12-30 DK DK99965579T patent/DK1140149T3/da active
- 1999-12-30 PT PT99965579T patent/PT1140149E/pt unknown
- 1999-12-30 IL IL14399499A patent/IL143994A0/xx unknown
- 1999-12-30 SI SI9930937T patent/SI1140149T1/sl unknown
- 1999-12-30 JP JP2000592015A patent/JP4808316B2/ja not_active Expired - Fee Related
- 1999-12-30 AT AT99965579T patent/ATE342064T1/de active
- 1999-12-30 ES ES99965579T patent/ES2275359T3/es not_active Expired - Lifetime
- 1999-12-30 EP EP06021178A patent/EP1779865A1/en not_active Withdrawn
- 1999-12-30 DE DE69933581T patent/DE69933581T2/de not_active Expired - Lifetime
- 1999-12-30 CA CA002354194A patent/CA2354194A1/en not_active Abandoned
- 1999-12-30 AU AU21039/00A patent/AU772222B2/en not_active Ceased
- 1999-12-30 BR BR9916726-3A patent/BR9916726A/pt not_active Application Discontinuation
- 1999-12-30 EP EP99965579A patent/EP1140149B1/en not_active Expired - Lifetime
-
2001
- 2001-06-26 IL IL143994A patent/IL143994A/en not_active IP Right Cessation
-
2004
- 2004-07-22 AU AU2004203355A patent/AU2004203355B2/en not_active Ceased
-
2005
- 2005-09-29 US US11/237,876 patent/US20060029581A1/en not_active Abandoned
-
2007
- 2007-01-08 CY CY20071100021T patent/CY1107603T1/el unknown
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07505527A (ja) * | 1992-03-30 | 1995-06-22 | シェリング・コーポレーション | ヒト樹状細胞のインビトロ発生およびそれらの用途 |
| JPH07101877A (ja) * | 1993-10-04 | 1995-04-18 | Mitsui Toatsu Chem Inc | 血小板減少症治療剤 |
| JPH09506245A (ja) * | 1993-10-06 | 1997-06-24 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイテッド | 幹細胞増殖因子 |
| JPH0892001A (ja) * | 1994-09-26 | 1996-04-09 | Asahi Medical Co Ltd | 細胞集団の保存方法 |
| WO1997003684A1 (en) * | 1995-07-21 | 1997-02-06 | THE GOVERNMENT OF THE UNITED STATES, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Method of decreasing radiation or radio-mimetic chemotherapy for hematopoietic pluripotent cell engraftment |
| WO1997026326A1 (en) * | 1996-01-16 | 1997-07-24 | Depuy Orthopaedics, Inc. | Isolation of precursor cells from hematopoietic and non-hematopoietic tissues and their use |
| JPH10206423A (ja) * | 1996-11-20 | 1998-08-07 | Toa Medical Electronics Co Ltd | 幼若白血球の分類計数法 |
| JPH10295369A (ja) * | 1997-02-26 | 1998-11-10 | Japan Tobacco Inc | 造血幹細胞の製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000040260A1 (en) | 2000-07-13 |
| AU2103900A (en) | 2000-07-24 |
| JP2002534393A (ja) | 2002-10-15 |
| US20060029581A1 (en) | 2006-02-09 |
| IL143994A0 (en) | 2002-04-21 |
| DE69933581T2 (de) | 2007-06-21 |
| AU2004203355B2 (en) | 2007-05-17 |
| EP1140149B1 (en) | 2006-10-11 |
| AU772222B2 (en) | 2004-04-22 |
| EP1779865A1 (en) | 2007-05-02 |
| ATE342064T1 (de) | 2006-11-15 |
| EP1016413A1 (en) | 2000-07-05 |
| SI1140149T1 (sl) | 2007-02-28 |
| DK1140149T3 (da) | 2007-02-19 |
| IL143994A (en) | 2009-06-15 |
| CY1107603T1 (el) | 2013-03-13 |
| AU2004203355A1 (en) | 2004-08-19 |
| DE69933581D1 (de) | 2006-11-23 |
| EP1140149A1 (en) | 2001-10-10 |
| BR9916726A (pt) | 2001-09-11 |
| CA2354194A1 (en) | 2000-07-13 |
| PT1140149E (pt) | 2007-01-31 |
| ES2275359T3 (es) | 2007-06-01 |
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