JP4677728B2 - 共焦点顕微鏡及び共焦点顕微鏡システム - Google Patents

共焦点顕微鏡及び共焦点顕微鏡システム Download PDF

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Publication number
JP4677728B2
JP4677728B2 JP2004083319A JP2004083319A JP4677728B2 JP 4677728 B2 JP4677728 B2 JP 4677728B2 JP 2004083319 A JP2004083319 A JP 2004083319A JP 2004083319 A JP2004083319 A JP 2004083319A JP 4677728 B2 JP4677728 B2 JP 4677728B2
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light
confocal microscope
reflection
light beam
region
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Expired - Fee Related
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JP2004083319A
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English (en)
Japanese (ja)
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JP2005274591A5 (enExample
JP2005274591A (ja
Inventor
久 奥川
直志 相川
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Nikon Corp
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Nikon Corp
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Publication date
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Priority to JP2004083319A priority Critical patent/JP4677728B2/ja
Priority to US11/081,731 priority patent/US7271953B2/en
Priority to DE102005012993A priority patent/DE102005012993A1/de
Priority to GB0505755A priority patent/GB2412528B/en
Publication of JP2005274591A publication Critical patent/JP2005274591A/ja
Publication of JP2005274591A5 publication Critical patent/JP2005274591A5/ja
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036—Scanning details, e.g. scanning stages
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036—Scanning details, e.g. scanning stages
    • G02B21/0044—Scanning details, e.g. scanning stages moving apertures, e.g. Nipkow disks, rotating lens arrays
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/006—Optical details of the image generation focusing arrangements; selection of the plane to be imaged
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008—Details of detection or image processing, including general computer control

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Engineering & Computer Science (AREA)
  • Microscoopes, Condenser (AREA)
JP2004083319A 2004-03-22 2004-03-22 共焦点顕微鏡及び共焦点顕微鏡システム Expired - Fee Related JP4677728B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2004083319A JP4677728B2 (ja) 2004-03-22 2004-03-22 共焦点顕微鏡及び共焦点顕微鏡システム
US11/081,731 US7271953B2 (en) 2004-03-22 2005-03-17 Confocal microscope
DE102005012993A DE102005012993A1 (de) 2004-03-22 2005-03-21 Konfokales Mikroskop
GB0505755A GB2412528B (en) 2004-03-22 2005-03-21 Confocal microscope

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2004083319A JP4677728B2 (ja) 2004-03-22 2004-03-22 共焦点顕微鏡及び共焦点顕微鏡システム

Publications (3)

Publication Number Publication Date
JP2005274591A JP2005274591A (ja) 2005-10-06
JP2005274591A5 JP2005274591A5 (enExample) 2007-06-14
JP4677728B2 true JP4677728B2 (ja) 2011-04-27

Family

ID=34545165

Family Applications (1)

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JP2004083319A Expired - Fee Related JP4677728B2 (ja) 2004-03-22 2004-03-22 共焦点顕微鏡及び共焦点顕微鏡システム

Country Status (4)

Country Link
US (1) US7271953B2 (enExample)
JP (1) JP4677728B2 (enExample)
DE (1) DE102005012993A1 (enExample)
GB (1) GB2412528B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0221014D0 (en) * 2002-09-11 2002-10-23 Medical Res Council Spectral discrimination apparatus and method
US20100049055A1 (en) * 2005-05-31 2010-02-25 W.O.M. World Of Medicine Ag Method and apparatus for visual characterization of tissue
JP2007279085A (ja) * 2006-04-03 2007-10-25 Nikon Corp 共焦点顕微鏡
US8040495B2 (en) * 2007-02-26 2011-10-18 Koninklijke Philips Electronics N.V. Method and device for optical analysis of a tissue
WO2008152802A1 (ja) 2007-06-13 2008-12-18 Nikon Corporation 共焦点顕微鏡装置
JP4968337B2 (ja) * 2007-06-15 2012-07-04 株式会社ニコン 共焦点顕微鏡装置
DE102010006662B4 (de) * 2010-02-03 2019-07-25 Diehl Defence Gmbh & Co. Kg Vorrichtung und Verfahren zum Abbilden einer Umgebung auf eine Detektoreinrichtung
DE112015001154T5 (de) 2014-04-24 2016-12-08 Olympus Corporation Mikroskop und Mikroskopie-Verfahren
CN104296687A (zh) * 2014-11-05 2015-01-21 哈尔滨工业大学 基于荧光共焦显微技术的光滑大曲率样品测量装置与方法
CN104568884B (zh) * 2014-12-31 2017-03-29 深圳先进技术研究院 基于焦点调制的荧光显微系统及方法
JP6594437B2 (ja) 2015-09-15 2019-10-23 オリンパス株式会社 顕微鏡および顕微鏡観察方法
WO2019118582A2 (en) * 2017-12-12 2019-06-20 Trustees Of Boston University Multi-z confocal imaging system
CN108759698B (zh) * 2018-08-02 2020-02-14 淮阴师范学院 多镜面透镜组镜面间距的低相干光干涉测量方法和装置
CN119173798A (zh) * 2022-05-16 2024-12-20 高露洁-棕榄公司 用于使用镜面针孔阵列对多于一个样品平面同时采样的技术

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH073508B2 (ja) * 1989-02-22 1995-01-18 浜松ホトニクス株式会社 コンフオーカルスキヤンニング顕微鏡
JPH0616927A (ja) 1992-06-30 1994-01-25 Kanebo Ltd ポリアミド樹脂組成物
US5886784A (en) * 1993-09-08 1999-03-23 Leica Lasertechink Gmbh Device for the selection and detection of at least two spectral regions in a beam of light
DE4330347C2 (de) 1993-09-08 1998-04-09 Leica Lasertechnik Verwendung einer Vorrichtung zur Selektion und Detektion mindestens zweier Spektralbereiche eines Lichtstrahls
JPH08136815A (ja) * 1994-11-11 1996-05-31 Olympus Optical Co Ltd 共焦点走査型光学顕微鏡
US5932871A (en) * 1995-11-08 1999-08-03 Olympus Optical Co., Ltd. Microscope having a confocal point and a non-confocal point, and a confocal point detect method applied thereto
DE19650391C2 (de) * 1996-12-05 2001-07-26 Leica Microsystems Anordnung zur simultanen polyfokalen Abbildung des Oberflächenprofils beliebiger Objekte
JP3816632B2 (ja) * 1997-05-14 2006-08-30 オリンパス株式会社 走査型顕微鏡
JPH11237557A (ja) * 1998-02-23 1999-08-31 Olympus Optical Co Ltd 走査型光学顕微鏡
GB9825267D0 (en) * 1998-11-19 1999-01-13 Medical Res Council Scanning confocal optical microscope system
US6423960B1 (en) * 1999-12-31 2002-07-23 Leica Microsystems Heidelberg Gmbh Method and system for processing scan-data from a confocal microscope
DE10132638A1 (de) * 2001-07-05 2003-01-16 Leica Microsystems Scanmikroskop und Verfahren zur wellenlängenabhängigen Detektion

Also Published As

Publication number Publication date
GB0505755D0 (en) 2005-04-27
GB2412528A (en) 2005-09-28
DE102005012993A1 (de) 2005-10-13
GB2412528B (en) 2009-10-21
JP2005274591A (ja) 2005-10-06
US20050213206A1 (en) 2005-09-29
US7271953B2 (en) 2007-09-18

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