GB2412528B - Confocal microscope - Google Patents

Confocal microscope

Info

Publication number
GB2412528B
GB2412528B GB0505755A GB0505755A GB2412528B GB 2412528 B GB2412528 B GB 2412528B GB 0505755 A GB0505755 A GB 0505755A GB 0505755 A GB0505755 A GB 0505755A GB 2412528 B GB2412528 B GB 2412528B
Authority
GB
United Kingdom
Prior art keywords
confocal microscope
confocal
microscope
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB0505755A
Other languages
English (en)
Other versions
GB0505755D0 (en
GB2412528A (en
Inventor
Hisashi Okugawa
Naoshi Aikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nikon Corp
Original Assignee
Nikon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nikon Corp filed Critical Nikon Corp
Publication of GB0505755D0 publication Critical patent/GB0505755D0/en
Publication of GB2412528A publication Critical patent/GB2412528A/en
Application granted granted Critical
Publication of GB2412528B publication Critical patent/GB2412528B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036—Scanning details, e.g. scanning stages
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036—Scanning details, e.g. scanning stages
    • G02B21/0044—Scanning details, e.g. scanning stages moving apertures, e.g. Nipkow disks, rotating lens arrays
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/006—Optical details of the image generation focusing arrangements; selection of the plane to be imaged
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008—Details of detection or image processing, including general computer control

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Engineering & Computer Science (AREA)
  • Microscoopes, Condenser (AREA)
GB0505755A 2004-03-22 2005-03-21 Confocal microscope Expired - Fee Related GB2412528B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2004083319A JP4677728B2 (ja) 2004-03-22 2004-03-22 共焦点顕微鏡及び共焦点顕微鏡システム

Publications (3)

Publication Number Publication Date
GB0505755D0 GB0505755D0 (en) 2005-04-27
GB2412528A GB2412528A (en) 2005-09-28
GB2412528B true GB2412528B (en) 2009-10-21

Family

ID=34545165

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0505755A Expired - Fee Related GB2412528B (en) 2004-03-22 2005-03-21 Confocal microscope

Country Status (4)

Country Link
US (1) US7271953B2 (enExample)
JP (1) JP4677728B2 (enExample)
DE (1) DE102005012993A1 (enExample)
GB (1) GB2412528B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0221014D0 (en) * 2002-09-11 2002-10-23 Medical Res Council Spectral discrimination apparatus and method
US20100049055A1 (en) * 2005-05-31 2010-02-25 W.O.M. World Of Medicine Ag Method and apparatus for visual characterization of tissue
JP2007279085A (ja) * 2006-04-03 2007-10-25 Nikon Corp 共焦点顕微鏡
US8040495B2 (en) * 2007-02-26 2011-10-18 Koninklijke Philips Electronics N.V. Method and device for optical analysis of a tissue
WO2008152802A1 (ja) 2007-06-13 2008-12-18 Nikon Corporation 共焦点顕微鏡装置
JP4968337B2 (ja) * 2007-06-15 2012-07-04 株式会社ニコン 共焦点顕微鏡装置
DE102010006662B4 (de) * 2010-02-03 2019-07-25 Diehl Defence Gmbh & Co. Kg Vorrichtung und Verfahren zum Abbilden einer Umgebung auf eine Detektoreinrichtung
DE112015001154T5 (de) 2014-04-24 2016-12-08 Olympus Corporation Mikroskop und Mikroskopie-Verfahren
CN104296687A (zh) * 2014-11-05 2015-01-21 哈尔滨工业大学 基于荧光共焦显微技术的光滑大曲率样品测量装置与方法
CN104568884B (zh) * 2014-12-31 2017-03-29 深圳先进技术研究院 基于焦点调制的荧光显微系统及方法
JP6594437B2 (ja) 2015-09-15 2019-10-23 オリンパス株式会社 顕微鏡および顕微鏡観察方法
WO2019118582A2 (en) * 2017-12-12 2019-06-20 Trustees Of Boston University Multi-z confocal imaging system
CN108759698B (zh) * 2018-08-02 2020-02-14 淮阴师范学院 多镜面透镜组镜面间距的低相干光干涉测量方法和装置
CN119173798A (zh) * 2022-05-16 2024-12-20 高露洁-棕榄公司 用于使用镜面针孔阵列对多于一个样品平面同时采样的技术

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4330347A1 (de) * 1993-09-08 1995-03-16 Leica Lasertechnik Vorrichtung zur Selektion und Detektion mindestens zweier Spektralbereiche eines Lichtstrahls
GB2344014A (en) * 1998-11-19 2000-05-24 Medical Res Council Scanning confocal optical microscope system
US6150666A (en) * 1996-12-05 2000-11-21 Leica Microsystems Heidelberg Gmbh Polyfocal representation of the surface profile of any given object

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH073508B2 (ja) * 1989-02-22 1995-01-18 浜松ホトニクス株式会社 コンフオーカルスキヤンニング顕微鏡
JPH0616927A (ja) 1992-06-30 1994-01-25 Kanebo Ltd ポリアミド樹脂組成物
US5886784A (en) * 1993-09-08 1999-03-23 Leica Lasertechink Gmbh Device for the selection and detection of at least two spectral regions in a beam of light
JPH08136815A (ja) * 1994-11-11 1996-05-31 Olympus Optical Co Ltd 共焦点走査型光学顕微鏡
US5932871A (en) * 1995-11-08 1999-08-03 Olympus Optical Co., Ltd. Microscope having a confocal point and a non-confocal point, and a confocal point detect method applied thereto
JP3816632B2 (ja) * 1997-05-14 2006-08-30 オリンパス株式会社 走査型顕微鏡
JPH11237557A (ja) * 1998-02-23 1999-08-31 Olympus Optical Co Ltd 走査型光学顕微鏡
US6423960B1 (en) * 1999-12-31 2002-07-23 Leica Microsystems Heidelberg Gmbh Method and system for processing scan-data from a confocal microscope
DE10132638A1 (de) * 2001-07-05 2003-01-16 Leica Microsystems Scanmikroskop und Verfahren zur wellenlängenabhängigen Detektion

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4330347A1 (de) * 1993-09-08 1995-03-16 Leica Lasertechnik Vorrichtung zur Selektion und Detektion mindestens zweier Spektralbereiche eines Lichtstrahls
US6150666A (en) * 1996-12-05 2000-11-21 Leica Microsystems Heidelberg Gmbh Polyfocal representation of the surface profile of any given object
GB2344014A (en) * 1998-11-19 2000-05-24 Medical Res Council Scanning confocal optical microscope system

Also Published As

Publication number Publication date
GB0505755D0 (en) 2005-04-27
GB2412528A (en) 2005-09-28
DE102005012993A1 (de) 2005-10-13
JP2005274591A (ja) 2005-10-06
JP4677728B2 (ja) 2011-04-27
US20050213206A1 (en) 2005-09-29
US7271953B2 (en) 2007-09-18

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20140321