JP4624673B2 - 化合物の経皮輸送 - Google Patents

化合物の経皮輸送 Download PDF

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Publication number
JP4624673B2
JP4624673B2 JP2003550823A JP2003550823A JP4624673B2 JP 4624673 B2 JP4624673 B2 JP 4624673B2 JP 2003550823 A JP2003550823 A JP 2003550823A JP 2003550823 A JP2003550823 A JP 2003550823A JP 4624673 B2 JP4624673 B2 JP 4624673B2
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JP
Japan
Prior art keywords
group
phosphate
chohch
coox
phosphate ester
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Expired - Fee Related
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JP2003550823A
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English (en)
Japanese (ja)
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JP2005511725A (ja
JP2005511725A5 (enExample
Inventor
マイケル ウエスト，サイモン
カナー，デイビッド
Original Assignee
バイタル ヘルス サイエンシズ プロプライアタリー リミティド
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Filing date
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Priority claimed from AUPR9463A external-priority patent/AUPR946301A0/en
Priority claimed from AU2002950711A external-priority patent/AU2002950711A0/en
Application filed by バイタル ヘルス サイエンシズ プロプライアタリー リミティド filed Critical バイタル ヘルス サイエンシズ プロプライアタリー リミティド
Publication of JP2005511725A publication Critical patent/JP2005511725A/ja
Publication of JP2005511725A5 publication Critical patent/JP2005511725A5/ja
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Publication of JP4624673B2 publication Critical patent/JP4624673B2/ja
Anticipated expiration legal-status Critical
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Addiction (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2003550823A 2001-12-13 2002-12-13 化合物の経皮輸送 Expired - Fee Related JP4624673B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPR9463A AUPR946301A0 (en) 2001-12-13 2001-12-13 Transdermal therapy
AU2002950711A AU2002950711A0 (en) 2002-08-09 2002-08-09 Transdermal transport of compounds
PCT/AU2002/001686 WO2003049774A1 (en) 2001-12-13 2002-12-13 Transdermal transport of compounds

Publications (3)

Publication Number Publication Date
JP2005511725A JP2005511725A (ja) 2005-04-28
JP2005511725A5 JP2005511725A5 (enExample) 2010-07-22
JP4624673B2 true JP4624673B2 (ja) 2011-02-02

Family

ID=25646859

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003550823A Expired - Fee Related JP4624673B2 (ja) 2001-12-13 2002-12-13 化合物の経皮輸送

Country Status (11)

Country Link
US (1) US20050089495A1 (enExample)
EP (1) EP1460995B1 (enExample)
JP (1) JP4624673B2 (enExample)
CN (1) CN1604772A (enExample)
AT (1) ATE487456T1 (enExample)
AU (1) AU2002350272B1 (enExample)
BR (1) BR0215102A (enExample)
CA (1) CA2466536C (enExample)
DE (1) DE60238276D1 (enExample)
MX (1) MXPA04005361A (enExample)
WO (1) WO2003049774A1 (enExample)

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US8008345B2 (en) 2001-07-27 2011-08-30 Vital Health Sciences Pty. Ltd. Dermal therapy using phosphate derivatives of electron transfer agents
EP1460995B1 (en) * 2001-12-13 2010-11-10 Vital Health Sciences Pty Ltd. Transdermal transport of compounds
AU2002950713A0 (en) * 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
KR20050086954A (ko) * 2003-01-17 2005-08-30 바이탈 헬스 사이언시즈 피티와이 리미티드 항증식성 화합물
AU2003901815A0 (en) * 2003-04-15 2003-05-01 Vital Health Sciences Pty Ltd Phosphate derivatives
AU2003901813A0 (en) * 2003-04-15 2003-05-01 Vital Health Sciences Pty Ltd Pharmaceutical derivatives
WO2005084678A1 (en) 2004-03-03 2005-09-15 Vital Health Sciences Pty Ltd Alkaloid formulations
EP1778289B1 (en) * 2004-08-03 2011-01-12 Vital Health Sciences Pty Ltd. Carrier for enteral administration
US20090233881A1 (en) * 2005-03-03 2009-09-17 Vital Health Sciences Pty. Ltd Compounds having anti-cancer properties
EP2548581A3 (en) * 2005-06-17 2013-02-20 Vital Health Sciences Pty Ltd. A carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
RU2008123556A (ru) * 2005-12-23 2010-01-27 Вайтал Хэлф Сайнсис Пти Лтд (Au) Составы, имеющие цитокин модулирующие свойства
JP2007308403A (ja) * 2006-05-17 2007-11-29 Kenji Yoshida 皮膚外用剤
US8491927B2 (en) * 2009-12-02 2013-07-23 Nimble Epitech, Llc Pharmaceutical composition containing a hypomethylating agent and a histone deacetylase inhibitor
ES2643643T3 (es) * 2009-12-23 2017-11-23 Phosphagenics Limited Composición portadora para suministro de un compuesto biológicamente activo
AU2011213557B2 (en) 2010-02-05 2015-05-07 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
US8652511B2 (en) 2010-03-30 2014-02-18 Phosphagenics Limited Transdermal delivery patch
WO2011120070A1 (en) * 2010-03-30 2011-10-06 Phosphagenics Limited Transdermal delivery patch
US9561243B2 (en) 2011-03-15 2017-02-07 Phosphagenics Limited Composition comprising non-neutralised tocol phosphate and a vitamin A compound
KR20160001419A (ko) * 2014-06-27 2016-01-06 포항공과대학교 산학협력단 양이온성 분자 수송체 및 음이온성 생리활성 물질을 포함하는 피부 투과용 조성물
CN108601732A (zh) 2015-12-09 2018-09-28 磷肌酸有限公司 药物制剂
IL267006B2 (en) * 2016-12-21 2024-11-01 Phosphagenics Ltd Process for phosphorylation of a complex alcohol with p4o10 at high temperatures, and products thereof
CN109589331B (zh) * 2019-02-19 2021-02-19 刘晓双 一种抑制术后静脉血栓形成的外用药物及其用途
WO2022155656A1 (en) 2021-01-13 2022-07-21 Rodan & Fields, Llc Cosmetic compositions

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US20050089495A1 (en) 2005-04-28
BR0215102A (pt) 2004-11-03
EP1460995A4 (en) 2007-11-21
CA2466536C (en) 2012-02-07
DE60238276D1 (de) 2010-12-23
WO2003049774A1 (en) 2003-06-19
CN1604772A (zh) 2005-04-06
EP1460995A1 (en) 2004-09-29
CA2466536A1 (en) 2003-06-19
ATE487456T1 (de) 2010-11-15
MXPA04005361A (es) 2004-09-27
AU2002350272B1 (en) 2003-06-23
EP1460995B1 (en) 2010-11-10

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