JP4612261B2 - 予め作製されたリポソームへの精製膜蛋白質の再構成 - Google Patents
予め作製されたリポソームへの精製膜蛋白質の再構成 Download PDFInfo
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- JP4612261B2 JP4612261B2 JP2001542908A JP2001542908A JP4612261B2 JP 4612261 B2 JP4612261 B2 JP 4612261B2 JP 2001542908 A JP2001542908 A JP 2001542908A JP 2001542908 A JP2001542908 A JP 2001542908A JP 4612261 B2 JP4612261 B2 JP 4612261B2
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Classifications
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/829—Liposomes, e.g. encapsulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
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- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/459,137 | 1999-12-10 | ||
| US09/459,137 US6248353B1 (en) | 1999-12-10 | 1999-12-10 | Reconstitution of purified membrane proteins into preformed liposomes |
| PCT/US2000/031927 WO2001041740A2 (en) | 1999-12-10 | 2000-11-20 | Reconstitution of purified membrane proteins into preformed liposomes |
Publications (3)
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| JP2003516525A JP2003516525A (ja) | 2003-05-13 |
| JP2003516525A5 JP2003516525A5 (https=) | 2007-11-22 |
| JP4612261B2 true JP4612261B2 (ja) | 2011-01-12 |
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| JP2001542908A Expired - Fee Related JP4612261B2 (ja) | 1999-12-10 | 2000-11-20 | 予め作製されたリポソームへの精製膜蛋白質の再構成 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6248353B1 (https=) |
| EP (1) | EP1239833B1 (https=) |
| JP (1) | JP4612261B2 (https=) |
| AT (1) | ATE272393T1 (https=) |
| DE (1) | DE60012785T2 (https=) |
| ES (1) | ES2225271T3 (https=) |
| WO (1) | WO2001041740A2 (https=) |
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| US20020048596A1 (en) * | 1994-12-30 | 2002-04-25 | Gregor Cevc | Preparation for the transport of an active substance across barriers |
| PT1031347E (pt) | 1999-01-27 | 2002-09-30 | Idea Ag | Transporte/imunizacao transnasal com veiculos muitissimo adaptaveis |
| ATE216875T1 (de) | 1999-01-27 | 2002-05-15 | Idea Ag | Nichtinvasive impfung durch die haut |
| WO2001001962A1 (en) * | 1999-07-05 | 2001-01-11 | Idea Ag. | A method for the improvement of transport across adaptable semi-permeable barriers |
| US6248353B1 (en) * | 1999-12-10 | 2001-06-19 | Dade Behring Inc. | Reconstitution of purified membrane proteins into preformed liposomes |
| DK1345959T3 (da) * | 2000-11-20 | 2011-09-05 | Univ Illinois | Membranscaffoldproteiner |
| US7592008B2 (en) * | 2000-11-20 | 2009-09-22 | The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois | Membrane scaffold proteins |
| US7622437B2 (en) * | 2000-11-20 | 2009-11-24 | The Board Of Trustees Of The University Of Illinois | Tissue factor compositions and methods |
| US7083958B2 (en) * | 2000-11-20 | 2006-08-01 | The Board Of Trustees Of The University Of Illinois | Membrane scaffold proteins |
| US6596543B2 (en) * | 2001-03-22 | 2003-07-22 | Dade Behring Inc. | Use of liposomes of defined composition and size for the preparation of prothrombin time reagents |
| US7015193B2 (en) * | 2001-04-20 | 2006-03-21 | University Of Vermont | Compositions and methods to control bleeding |
| WO2003075889A1 (en) * | 2002-03-05 | 2003-09-18 | Transave, Inc. | An inhalation system for prevention and treatment of intracellular infections |
| US20040105881A1 (en) * | 2002-10-11 | 2004-06-03 | Gregor Cevc | Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin |
| US20050032113A1 (en) * | 2003-07-17 | 2005-02-10 | Mitsubishi Pharma Corporation | Membrane protein library for proteome analysis and method for preparing same |
| KR101076578B1 (ko) | 2004-06-23 | 2011-10-24 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 2입자 착물을 이용한 생물학적 분자의 검출을 위한 방법 및조성물 |
| US7148067B2 (en) * | 2004-08-31 | 2006-12-12 | The Board Of Trustees Of The University Of Illinois | Thromboplastin reagents |
| JP2008519784A (ja) * | 2004-11-12 | 2008-06-12 | イデア アクチェンゲゼルシャフト | 皮膚状態の治療における拡張表面凝集体 |
| US20080260858A1 (en) * | 2005-02-16 | 2008-10-23 | The Board Of Trustees Of The University Of Illnois | Universal Procoagulant |
| AT501650A1 (de) * | 2005-02-22 | 2006-10-15 | Technoclone Ges M B H | Verfahren zur bestimmung der gerinnungsaktivierung sowie gerät zur durchführung des verfahrens |
| JP2008531692A (ja) * | 2005-03-04 | 2008-08-14 | ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ | 凝固及び線維素溶解カスケードのモジュレーター |
| US20080248565A1 (en) * | 2007-03-01 | 2008-10-09 | Invitrogen Corporation | Isolated phospholipid-protein particles |
| US20070117179A1 (en) * | 2005-09-27 | 2007-05-24 | Invitrogen Corporation | In vitro protein synthesis systems for membrane proteins that include adolipoproteins and phospholipid-adolipoprotein particles |
| JP2007106679A (ja) * | 2005-10-11 | 2007-04-26 | Shino Test Corp | 血液凝固反応促進剤 |
| EP1939218A1 (en) * | 2006-12-29 | 2008-07-02 | Thrombotargets Europe, S.L. | Microvesicles derived from recombinant yeast having haemostatic activities and uses thereof |
| US7943168B2 (en) | 2007-03-05 | 2011-05-17 | Washington University | Nanoparticle delivery systems comprising a hydrophobic core and a lipid/surfactant layer comprising a membrane-lytic peptide |
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| JPS56129859A (en) * | 1980-03-14 | 1981-10-12 | Sekisui Chem Co Ltd | Plastic container for blood inspection |
| US4873089A (en) * | 1985-07-12 | 1989-10-10 | Cornell Research Foundation Inc., Cornell University | Proteoliposomes as drug carriers |
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| JPH0650999B2 (ja) | 1988-09-12 | 1994-07-06 | 日本商事株式会社 | 血液凝固因子安定化法 |
| US5472850A (en) | 1991-04-10 | 1995-12-05 | Oklahoma Medical Research Foundation | Quantitative clotting assay for activated factor VII |
| ES2120949T4 (es) | 1990-06-28 | 2011-12-29 | Sanofi-Aventis Deutschland Gmbh 50% | Proteinas de fusión con porciones de inmunoglobulinas, su preparación y empleo. |
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| ATE163768T1 (de) * | 1991-10-04 | 1998-03-15 | Dade Int Inc | Herstellung von prothrombinzeit-reagenzien aus rekombinantem menschlichem gewebefaktor und sythetischen phospholipiden |
| AU674139B2 (en) | 1992-04-13 | 1996-12-12 | Ortho Diagnostic Systems Inc. | Synthetic phospholipid reagent |
| US5358853A (en) | 1992-08-03 | 1994-10-25 | Akzo Av | Liquid thromboplastin reagent |
| DE4243729A1 (de) | 1992-12-23 | 1994-06-30 | Behringwerke Ag | Verfahren zur Reaktivierung von gereinigten Membranproteinen |
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| DE4416166C2 (de) | 1994-05-06 | 1997-11-20 | Immuno Ag | Stabiles Präparat zur Behandlung von Blutgerinnungsstörungen |
| EP1015890B1 (en) * | 1997-04-23 | 2005-11-30 | INSTRUMENTATION LABORATORY S.p.A. | Recombinant rabbit tissue factor based prothrombin time reagent |
| JP4039722B2 (ja) * | 1997-12-01 | 2008-01-30 | シスメックス株式会社 | 複合因子測定試薬 |
| US6248353B1 (en) * | 1999-12-10 | 2001-06-19 | Dade Behring Inc. | Reconstitution of purified membrane proteins into preformed liposomes |
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| US6706861B2 (en) | 2004-03-16 |
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| EP1239833B1 (en) | 2004-08-04 |
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| WO2001041740A2 (en) | 2001-06-14 |
| JP2003516525A (ja) | 2003-05-13 |
| ATE272393T1 (de) | 2004-08-15 |
| EP1239833A2 (en) | 2002-09-18 |
| US20020012699A1 (en) | 2002-01-31 |
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