ATE272393T1 - Rekonstruktion gereinigter membranproteine in vorgefertigten liposomen - Google Patents
Rekonstruktion gereinigter membranproteine in vorgefertigten liposomenInfo
- Publication number
- ATE272393T1 ATE272393T1 AT00980600T AT00980600T ATE272393T1 AT E272393 T1 ATE272393 T1 AT E272393T1 AT 00980600 T AT00980600 T AT 00980600T AT 00980600 T AT00980600 T AT 00980600T AT E272393 T1 ATE272393 T1 AT E272393T1
- Authority
- AT
- Austria
- Prior art keywords
- liposomes
- solution
- providing
- mixture
- membrane proteins
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title abstract 7
- 108010052285 Membrane Proteins Proteins 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 abstract 4
- 102000002262 Thromboplastin Human genes 0.000 abstract 3
- 108010000499 Thromboplastin Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract 2
- 150000004670 unsaturated fatty acids Chemical class 0.000 abstract 2
- 102000018697 Membrane Proteins Human genes 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/829—Liposomes, e.g. encapsulation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Dispersion Chemistry (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/459,137 US6248353B1 (en) | 1999-12-10 | 1999-12-10 | Reconstitution of purified membrane proteins into preformed liposomes |
| PCT/US2000/031927 WO2001041740A2 (en) | 1999-12-10 | 2000-11-20 | Reconstitution of purified membrane proteins into preformed liposomes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE272393T1 true ATE272393T1 (de) | 2004-08-15 |
Family
ID=23823557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00980600T ATE272393T1 (de) | 1999-12-10 | 2000-11-20 | Rekonstruktion gereinigter membranproteine in vorgefertigten liposomen |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6248353B1 (https=) |
| EP (1) | EP1239833B1 (https=) |
| JP (1) | JP4612261B2 (https=) |
| AT (1) | ATE272393T1 (https=) |
| DE (1) | DE60012785T2 (https=) |
| ES (1) | ES2225271T3 (https=) |
| WO (1) | WO2001041740A2 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020048596A1 (en) * | 1994-12-30 | 2002-04-25 | Gregor Cevc | Preparation for the transport of an active substance across barriers |
| PT1031347E (pt) | 1999-01-27 | 2002-09-30 | Idea Ag | Transporte/imunizacao transnasal com veiculos muitissimo adaptaveis |
| ATE216875T1 (de) | 1999-01-27 | 2002-05-15 | Idea Ag | Nichtinvasive impfung durch die haut |
| WO2001001962A1 (en) * | 1999-07-05 | 2001-01-11 | Idea Ag. | A method for the improvement of transport across adaptable semi-permeable barriers |
| US6248353B1 (en) * | 1999-12-10 | 2001-06-19 | Dade Behring Inc. | Reconstitution of purified membrane proteins into preformed liposomes |
| DK1345959T3 (da) * | 2000-11-20 | 2011-09-05 | Univ Illinois | Membranscaffoldproteiner |
| US7592008B2 (en) * | 2000-11-20 | 2009-09-22 | The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois | Membrane scaffold proteins |
| US7622437B2 (en) * | 2000-11-20 | 2009-11-24 | The Board Of Trustees Of The University Of Illinois | Tissue factor compositions and methods |
| US7083958B2 (en) * | 2000-11-20 | 2006-08-01 | The Board Of Trustees Of The University Of Illinois | Membrane scaffold proteins |
| US6596543B2 (en) * | 2001-03-22 | 2003-07-22 | Dade Behring Inc. | Use of liposomes of defined composition and size for the preparation of prothrombin time reagents |
| US7015193B2 (en) * | 2001-04-20 | 2006-03-21 | University Of Vermont | Compositions and methods to control bleeding |
| WO2003075889A1 (en) * | 2002-03-05 | 2003-09-18 | Transave, Inc. | An inhalation system for prevention and treatment of intracellular infections |
| US20040105881A1 (en) * | 2002-10-11 | 2004-06-03 | Gregor Cevc | Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin |
| US20050032113A1 (en) * | 2003-07-17 | 2005-02-10 | Mitsubishi Pharma Corporation | Membrane protein library for proteome analysis and method for preparing same |
| KR101076578B1 (ko) | 2004-06-23 | 2011-10-24 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 2입자 착물을 이용한 생물학적 분자의 검출을 위한 방법 및조성물 |
| US7148067B2 (en) * | 2004-08-31 | 2006-12-12 | The Board Of Trustees Of The University Of Illinois | Thromboplastin reagents |
| JP2008519784A (ja) * | 2004-11-12 | 2008-06-12 | イデア アクチェンゲゼルシャフト | 皮膚状態の治療における拡張表面凝集体 |
| US20080260858A1 (en) * | 2005-02-16 | 2008-10-23 | The Board Of Trustees Of The University Of Illnois | Universal Procoagulant |
| AT501650A1 (de) * | 2005-02-22 | 2006-10-15 | Technoclone Ges M B H | Verfahren zur bestimmung der gerinnungsaktivierung sowie gerät zur durchführung des verfahrens |
| JP2008531692A (ja) * | 2005-03-04 | 2008-08-14 | ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・イリノイ | 凝固及び線維素溶解カスケードのモジュレーター |
| US20080248565A1 (en) * | 2007-03-01 | 2008-10-09 | Invitrogen Corporation | Isolated phospholipid-protein particles |
| US20070117179A1 (en) * | 2005-09-27 | 2007-05-24 | Invitrogen Corporation | In vitro protein synthesis systems for membrane proteins that include adolipoproteins and phospholipid-adolipoprotein particles |
| JP2007106679A (ja) * | 2005-10-11 | 2007-04-26 | Shino Test Corp | 血液凝固反応促進剤 |
| EP1939218A1 (en) * | 2006-12-29 | 2008-07-02 | Thrombotargets Europe, S.L. | Microvesicles derived from recombinant yeast having haemostatic activities and uses thereof |
| US7943168B2 (en) | 2007-03-05 | 2011-05-17 | Washington University | Nanoparticle delivery systems comprising a hydrophobic core and a lipid/surfactant layer comprising a membrane-lytic peptide |
| CA2700808C (en) | 2007-09-27 | 2017-11-14 | Immunovaccine Technologies Inc. | Use of liposomes in a carrier comprising a continuous hydrophobic phase for delivery of polynucleotides in vivo |
| EP2062661A1 (en) * | 2007-09-28 | 2009-05-27 | Proviron Holding | Organic de-icer removal |
| US20100209452A1 (en) * | 2007-10-03 | 2010-08-19 | Immunovaccine Technologies, Inc | Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof |
| WO2009046194A2 (en) * | 2007-10-05 | 2009-04-09 | The Board Of Trustees Of The University Of Illinois | Fibrin sealant |
| WO2009061697A1 (en) | 2007-11-09 | 2009-05-14 | The Board Of Trustees Of The University Of Illinois | Anticoagulant antagonist and hemophilia procoagulant |
| US20090220588A1 (en) * | 2008-02-21 | 2009-09-03 | Massachusetts Institute Of Technology | Simultaneous Delivery of Receptors and/or Co-Receptors for Growth Factor Stability and Activity |
| ES2524699T3 (es) | 2008-06-05 | 2014-12-11 | Immunovaccine Technologies Inc. | Composiciones que comprenden liposomas, un antígeno, un polinucleótido y un vehículo que comprende una fase continua de una sustancia hidrófoba |
| US8956600B2 (en) | 2009-08-10 | 2015-02-17 | Taiwan Liposome Co. Ltd. | Ophthalmic drug delivery system containing phospholipid and cholesterol |
| US10525152B2 (en) | 2009-10-09 | 2020-01-07 | Signablok, Inc. | Methods and compositions for targeted imaging |
| US10894098B2 (en) | 2012-04-09 | 2021-01-19 | Signablok, Inc. | Methods and compositions for targeted imaging |
| US12419839B2 (en) | 2009-10-09 | 2025-09-23 | Signablok, Inc. | Methods and compositions for targeted delivery of protein fragments |
| KR101458315B1 (ko) | 2013-07-19 | 2014-11-04 | 전북대학교산학협력단 | 표면 개질된 리포좀 및 그 제조방법 |
| JP6626761B2 (ja) | 2016-03-30 | 2019-12-25 | シスメックス株式会社 | プロトロンビン時間測定用試薬およびその製造方法 |
| JP6652873B2 (ja) * | 2016-03-30 | 2020-02-26 | シスメックス株式会社 | プロトロンビン時間測定用試薬、その製造方法およびプロトロンビン時間の測定方法 |
| WO2019200240A1 (en) | 2018-04-13 | 2019-10-17 | Board Of Regents, The University Of Texas System | Transmembrane stem cell factor (tm-scf) lipid nanocarriers and methods of use thereof |
| EP3819640B1 (en) * | 2018-07-06 | 2025-06-18 | PHC Corporation | Liposome-containing liquid reagent for measuring blood coagulation ability |
| JP7153519B2 (ja) | 2018-09-28 | 2022-10-14 | シスメックス株式会社 | 凝固時間測定用試薬及びその製造方法、試薬キット及び凝固時間の測定方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL238873A (https=) | 1958-05-16 | |||
| JPS56129859A (en) * | 1980-03-14 | 1981-10-12 | Sekisui Chem Co Ltd | Plastic container for blood inspection |
| US4873089A (en) * | 1985-07-12 | 1989-10-10 | Cornell Research Foundation Inc., Cornell University | Proteoliposomes as drug carriers |
| IL79114A (en) * | 1985-08-07 | 1990-09-17 | Allergan Pharma | Method and composition for making liposomes |
| JPH0650999B2 (ja) | 1988-09-12 | 1994-07-06 | 日本商事株式会社 | 血液凝固因子安定化法 |
| US5472850A (en) | 1991-04-10 | 1995-12-05 | Oklahoma Medical Research Foundation | Quantitative clotting assay for activated factor VII |
| ES2120949T4 (es) | 1990-06-28 | 2011-12-29 | Sanofi-Aventis Deutschland Gmbh 50% | Proteinas de fusión con porciones de inmunoglobulinas, su preparación y empleo. |
| US5314695A (en) | 1990-11-13 | 1994-05-24 | Corvas International, Inc. | Tissue factor based prothrombin time reagent |
| US5248590A (en) | 1991-07-22 | 1993-09-28 | Becton, Dickinson And Company | Surface modified liposomes |
| ATE163768T1 (de) * | 1991-10-04 | 1998-03-15 | Dade Int Inc | Herstellung von prothrombinzeit-reagenzien aus rekombinantem menschlichem gewebefaktor und sythetischen phospholipiden |
| AU674139B2 (en) | 1992-04-13 | 1996-12-12 | Ortho Diagnostic Systems Inc. | Synthetic phospholipid reagent |
| US5358853A (en) | 1992-08-03 | 1994-10-25 | Akzo Av | Liquid thromboplastin reagent |
| DE4243729A1 (de) | 1992-12-23 | 1994-06-30 | Behringwerke Ag | Verfahren zur Reaktivierung von gereinigten Membranproteinen |
| DE69530914T2 (de) | 1994-02-17 | 2004-03-11 | New York Blood Center, Inc. | Biologische bioadhäsive präparate, die fibrinkleber und liposomen enthalten, verfahren für ihre herstellung und verwendung |
| DE4416166C2 (de) | 1994-05-06 | 1997-11-20 | Immuno Ag | Stabiles Präparat zur Behandlung von Blutgerinnungsstörungen |
| EP1015890B1 (en) * | 1997-04-23 | 2005-11-30 | INSTRUMENTATION LABORATORY S.p.A. | Recombinant rabbit tissue factor based prothrombin time reagent |
| JP4039722B2 (ja) * | 1997-12-01 | 2008-01-30 | シスメックス株式会社 | 複合因子測定試薬 |
| US6248353B1 (en) * | 1999-12-10 | 2001-06-19 | Dade Behring Inc. | Reconstitution of purified membrane proteins into preformed liposomes |
-
1999
- 1999-12-10 US US09/459,137 patent/US6248353B1/en not_active Expired - Lifetime
-
2000
- 2000-11-20 ES ES00980600T patent/ES2225271T3/es not_active Expired - Lifetime
- 2000-11-20 AT AT00980600T patent/ATE272393T1/de active
- 2000-11-20 DE DE60012785T patent/DE60012785T2/de not_active Expired - Lifetime
- 2000-11-20 WO PCT/US2000/031927 patent/WO2001041740A2/en not_active Ceased
- 2000-11-20 JP JP2001542908A patent/JP4612261B2/ja not_active Expired - Fee Related
- 2000-11-20 EP EP00980600A patent/EP1239833B1/en not_active Expired - Lifetime
-
2001
- 2001-03-22 US US09/815,195 patent/US6706861B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2225271T3 (es) | 2005-03-16 |
| DE60012785D1 (de) | 2004-09-09 |
| US6706861B2 (en) | 2004-03-16 |
| DE60012785T2 (de) | 2005-08-11 |
| EP1239833B1 (en) | 2004-08-04 |
| WO2001041740A3 (en) | 2002-01-17 |
| WO2001041740A2 (en) | 2001-06-14 |
| JP2003516525A (ja) | 2003-05-13 |
| EP1239833A2 (en) | 2002-09-18 |
| US20020012699A1 (en) | 2002-01-31 |
| JP4612261B2 (ja) | 2011-01-12 |
| US6248353B1 (en) | 2001-06-19 |
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| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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