JP4558363B2 - 香料組成物 - Google Patents
香料組成物 Download PDFInfo
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- JP4558363B2 JP4558363B2 JP2004090937A JP2004090937A JP4558363B2 JP 4558363 B2 JP4558363 B2 JP 4558363B2 JP 2004090937 A JP2004090937 A JP 2004090937A JP 2004090937 A JP2004090937 A JP 2004090937A JP 4558363 B2 JP4558363 B2 JP 4558363B2
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- Prior art keywords
- estradiol
- amblet
- seed oil
- oil
- fragrance
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 239000003205 fragrance Substances 0.000 title description 11
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims description 28
- 229960005309 estradiol Drugs 0.000 claims description 16
- 230000028327 secretion Effects 0.000 claims description 13
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 12
- 230000000694 effects Effects 0.000 description 15
- 229940088597 hormone Drugs 0.000 description 15
- 239000005556 hormone Substances 0.000 description 15
- 229940011871 estrogen Drugs 0.000 description 10
- 239000000262 estrogen Substances 0.000 description 10
- 210000003296 saliva Anatomy 0.000 description 8
- 208000024891 symptom Diseases 0.000 description 8
- 210000003491 skin Anatomy 0.000 description 7
- 102000008186 Collagen Human genes 0.000 description 5
- 108010035532 Collagen Proteins 0.000 description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 5
- 229920001436 collagen Polymers 0.000 description 5
- 239000001262 hibiscus abelmoschus l. seed oil Substances 0.000 description 5
- 241000196324 Embryophyta Species 0.000 description 4
- 230000009245 menopause Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- NVIPUOMWGQAOIT-UHFFFAOYSA-N (E)-7-Hexadecen-16-olide Natural products O=C1CCCCCC=CCCCCCCCCO1 NVIPUOMWGQAOIT-UHFFFAOYSA-N 0.000 description 3
- NVIPUOMWGQAOIT-DUXPYHPUSA-N 7-hexadecen-1,16-olide Chemical compound O=C1CCCCC\C=C\CCCCCCCCO1 NVIPUOMWGQAOIT-DUXPYHPUSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
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- 229930182833 estradiol Natural products 0.000 description 3
- -1 for example Substances 0.000 description 3
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- 229920000742 Cotton Polymers 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 108010010803 Gelatin Proteins 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
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- DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 description 2
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- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- 230000001965 increasing effect Effects 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
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- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- DSEKYWAQQVUQTP-XEWMWGOFSA-N (2r,4r,4as,6as,6as,6br,8ar,12ar,14as,14bs)-2-hydroxy-4,4a,6a,6b,8a,11,11,14a-octamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydro-1h-picen-3-one Chemical compound C([C@H]1[C@]2(C)CC[C@@]34C)C(C)(C)CC[C@]1(C)CC[C@]2(C)[C@H]4CC[C@@]1(C)[C@H]3C[C@@H](O)C(=O)[C@@H]1C DSEKYWAQQVUQTP-XEWMWGOFSA-N 0.000 description 1
- RZRNAYUHWVFMIP-KTKRTIGZSA-N 1-oleoylglycerol Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(O)CO RZRNAYUHWVFMIP-KTKRTIGZSA-N 0.000 description 1
- 241001075517 Abelmoschus Species 0.000 description 1
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- 239000005995 Aluminium silicate Substances 0.000 description 1
- 208000019901 Anxiety disease Diseases 0.000 description 1
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 1
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 241000219104 Cucurbitaceae Species 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 238000008157 ELISA kit Methods 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- DNXHEGUUPJUMQT-CBZIJGRNSA-N Estrone Chemical compound OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 DNXHEGUUPJUMQT-CBZIJGRNSA-N 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 244000153234 Hibiscus abelmoschus Species 0.000 description 1
- 235000010616 Hibiscus abelmoschus Nutrition 0.000 description 1
- 208000033830 Hot Flashes Diseases 0.000 description 1
- 206010060800 Hot flush Diseases 0.000 description 1
- 235000019501 Lemon oil Nutrition 0.000 description 1
- 206010024264 Lethargy Diseases 0.000 description 1
- 241000219071 Malvaceae Species 0.000 description 1
- 229920000877 Melamine resin Polymers 0.000 description 1
- 239000004640 Melamine resin Substances 0.000 description 1
- 208000017657 Menopausal disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 241000237502 Ostreidae Species 0.000 description 1
- 244000170916 Paeonia officinalis Species 0.000 description 1
- 235000006484 Paeonia officinalis Nutrition 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- 241001579678 Panthea coenobita Species 0.000 description 1
- 229920002845 Poly(methacrylic acid) Chemical class 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004147 Sorbitan trioleate Substances 0.000 description 1
- PRXRUNOAOLTIEF-ADSICKODSA-N Sorbitan trioleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC PRXRUNOAOLTIEF-ADSICKODSA-N 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- 229920001807 Urea-formaldehyde Polymers 0.000 description 1
- IJCWFDPJFXGQBN-RYNSOKOISA-N [(2R)-2-[(2R,3R,4S)-4-hydroxy-3-octadecanoyloxyoxolan-2-yl]-2-octadecanoyloxyethyl] octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCCCCCCCCCCCC)[C@H]1OC[C@H](O)[C@H]1OC(=O)CCCCCCCCCCCCCCCCC IJCWFDPJFXGQBN-RYNSOKOISA-N 0.000 description 1
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- 239000008272 agar Substances 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 235000002783 ambrette Nutrition 0.000 description 1
- 244000096712 ambrette Species 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- 235000013871 bee wax Nutrition 0.000 description 1
- 239000012166 beeswax Substances 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 229940106189 ceramide Drugs 0.000 description 1
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
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- 230000000052 comparative effect Effects 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
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- 210000004207 dermis Anatomy 0.000 description 1
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- 239000000796 flavoring agent Substances 0.000 description 1
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- 210000004907 gland Anatomy 0.000 description 1
- RZRNAYUHWVFMIP-HXUWFJFHSA-N glycerol monolinoleate Natural products CCCCCCCCC=CCCCCCCCC(=O)OC[C@H](O)CO RZRNAYUHWVFMIP-HXUWFJFHSA-N 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 description 1
- 150000002515 isoflavone derivatives Chemical class 0.000 description 1
- 235000008696 isoflavones Nutrition 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000000171 lavandula angustifolia l. flower oil Substances 0.000 description 1
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- 239000000314 lubricant Substances 0.000 description 1
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- 239000002480 mineral oil Substances 0.000 description 1
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- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- 229920005615 natural polymer Polymers 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 description 1
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- 210000001672 ovary Anatomy 0.000 description 1
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Description
アンブレット・シード(種子)を産出する植物の一般名は、ニオイトロロアオイ、トロロアオイモドキと呼ばれる。この植物は熱帯アジア原産のアオイ科(Malvaceae)の一年草で、学名はAbelmoschus moschatus Moenchでオクラに似ているが果実は長さ8cm程の楕円形をしている。アンブレット・シード油と呼ばれるものには、アンブレット・シードコンクリート、アンブレット・シードアブソリュート、アンブレット・シードオイルがある。このうちアンブレット・シードコンクリートは、アンブレットの種子を揮発性溶剤で抽出し、その後溶剤を除去して得られるもので、このコンクリートをさらに水蒸気蒸留して得られるものが、アンブレット・シードアブソリュートである。通常天然香料の採取法において、アブソリュートは、コンクリートをアルコール抽出する方法で得られるが、この植物においては、アンブレット・シードコンクリートを水蒸気蒸留することにより得られるものがアンブレット・シードアブソリュートである。これは、コンクリート中に含まれる脂肪酸を除去するために行われる。また、アンブレット・シードオイルは、単にアンブレットの種子を水蒸気蒸留することによって得られるが、少量のパルミチン酸類が混入している。したがってこの精油は数ヶ月の熟成期間が必要で、熟成することにより脂肪酸臭が抑えられるという。香気は、豊かで甘く、フローラルムスキーでワイン様である。主香成分としてAmbrettolideを15%近く含有する(吉儀英記著,「香料入門」,フレグランスジャーナル社,p.213―215より)。
豊かで、きわめてフローラルムスキー香が強く、甘い香りのやや粘着性の無色のオイル。フレグランスには有用な保留剤であり、アルコールに0.01%加えるだけで保留効果が確認できる。保留剤ではあるが、フレグランスを引き立たせる効果があるといわれる(吉儀英記著,「香料入門」,フレグランスジャーナル社,p.215より)。
代表的エストロゲンである、17β−エストラジオールの唾液中の量を測定した。6名の被験者に、それぞれアンブレット・シードオイル又はアンブレットリドの香りを嗅がせ、香りを嗅ぐ前と、8分間香りを嗅がせその後10分間安静状態を保った後の、唾液中の17β−エストラジオールの濃度を比較した。
Claims (2)
- アンブレット・シード油又はアンブレットリドからなる17β−エストラジオール分泌促進剤。
- アンブレット・シード油が、アンブレット・シードアブソリュート又はアンブレット・シードオイルであることを特徴とする、請求項1記載の17β−エストラジオール分泌促進剤。
Priority Applications (1)
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JP2004090937A JP4558363B2 (ja) | 2003-06-19 | 2004-03-26 | 香料組成物 |
Applications Claiming Priority (2)
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JP2003174165 | 2003-06-19 | ||
JP2004090937A JP4558363B2 (ja) | 2003-06-19 | 2004-03-26 | 香料組成物 |
Publications (2)
Publication Number | Publication Date |
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JP2005029776A JP2005029776A (ja) | 2005-02-03 |
JP4558363B2 true JP4558363B2 (ja) | 2010-10-06 |
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JP2004090937A Expired - Lifetime JP4558363B2 (ja) | 2003-06-19 | 2004-03-26 | 香料組成物 |
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Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4550514B2 (ja) * | 2004-08-03 | 2010-09-22 | 花王株式会社 | ステロイドホルモン分泌調節剤 |
KR101531415B1 (ko) * | 2006-10-17 | 2015-06-24 | 바스프 뷰티 케어 솔루션즈 프랑스 에스에이에스 | Fgf-2 또는 fgf-베타 성장인자 보호 물질의 용도 |
US9925134B2 (en) | 2006-10-17 | 2018-03-27 | Basf Beauty Care Solutions France Sas | Use of substances to protect FGF-2 or FGF-beta growth factor |
FR2929511B1 (fr) * | 2008-04-02 | 2010-12-31 | Basf Beauty Care Solutions France Sas | Nouveau principe actif stimulant la proliferation et/ou l'activite des fibroblastes. |
JP2012031199A (ja) * | 2011-10-31 | 2012-02-16 | Kao Corp | 月経前及び/又は月経中の身体的及び/又は精神的不快の緩和剤 |
JP6498987B2 (ja) * | 2014-03-28 | 2019-04-10 | 株式会社コーセー | 透明油性化粧料 |
EP3313361B1 (en) * | 2015-06-29 | 2023-09-13 | Takasago International Corporation | Musk composition and methods of use thereof |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63501954A (ja) * | 1985-12-04 | 1988-08-04 | シエ−,デイ−ン | 医薬品の経皮施与 |
JPH0799946A (ja) * | 1993-09-30 | 1995-04-18 | Keiko Nakamura | 健康飲料 |
JPH10231496A (ja) * | 1997-02-17 | 1998-09-02 | Nagaoka Jitsugyo Kk | ハッカ組成物ならびにその製造方法 |
JP2000154394A (ja) * | 1998-11-18 | 2000-06-06 | Lion Corp | 香料組成物 |
JP2001174450A (ja) * | 1999-12-21 | 2001-06-29 | Shiseido Co Ltd | 香りの評価方法及び香りの評価質問紙 |
JP2001278763A (ja) * | 2000-03-30 | 2001-10-10 | Kobayashi Pharmaceut Co Ltd | 抗う蝕剤 |
WO2001098442A1 (fr) * | 2000-06-20 | 2001-12-27 | Shiseido Co., Ltd. | Parfums attenuant le stress et compositions attenuant le stress, contenant lesdits parfums |
JP2002255850A (ja) * | 2001-02-26 | 2002-09-11 | Shiseido Co Ltd | 皮膚老化抑制剤 |
JP2003113019A (ja) * | 2001-09-28 | 2003-04-18 | Lion Corp | 皮膚外用剤 |
JP2005519096A (ja) * | 2002-03-01 | 2005-06-30 | シーエスティー メディカル リミティド | 女性の性機能障害の治療薬 |
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2004
- 2004-03-26 JP JP2004090937A patent/JP4558363B2/ja not_active Expired - Lifetime
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JPS63501954A (ja) * | 1985-12-04 | 1988-08-04 | シエ−,デイ−ン | 医薬品の経皮施与 |
JPH0799946A (ja) * | 1993-09-30 | 1995-04-18 | Keiko Nakamura | 健康飲料 |
JPH10231496A (ja) * | 1997-02-17 | 1998-09-02 | Nagaoka Jitsugyo Kk | ハッカ組成物ならびにその製造方法 |
JP2000154394A (ja) * | 1998-11-18 | 2000-06-06 | Lion Corp | 香料組成物 |
JP2001174450A (ja) * | 1999-12-21 | 2001-06-29 | Shiseido Co Ltd | 香りの評価方法及び香りの評価質問紙 |
JP2001278763A (ja) * | 2000-03-30 | 2001-10-10 | Kobayashi Pharmaceut Co Ltd | 抗う蝕剤 |
WO2001098442A1 (fr) * | 2000-06-20 | 2001-12-27 | Shiseido Co., Ltd. | Parfums attenuant le stress et compositions attenuant le stress, contenant lesdits parfums |
JP2002255850A (ja) * | 2001-02-26 | 2002-09-11 | Shiseido Co Ltd | 皮膚老化抑制剤 |
JP2003113019A (ja) * | 2001-09-28 | 2003-04-18 | Lion Corp | 皮膚外用剤 |
JP2005519096A (ja) * | 2002-03-01 | 2005-06-30 | シーエスティー メディカル リミティド | 女性の性機能障害の治療薬 |
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