JP4520854B2 - 哺乳動物由来のグルコーストランスポーターの発現のための、サッカロミセス・セレビジエＥｒｇ４突然変異体の使用 - Google Patents

哺乳動物由来のグルコーストランスポーターの発現のための、サッカロミセス・セレビジエＥｒｇ４突然変異体の使用 Download PDF

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JP4520854B2
JP4520854B2 JP2004536979A JP2004536979A JP4520854B2 JP 4520854 B2 JP4520854 B2 JP 4520854B2 JP 2004536979 A JP2004536979 A JP 2004536979A JP 2004536979 A JP2004536979 A JP 2004536979A JP 4520854 B2 JP4520854 B2 JP 4520854B2
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protein
yeast
glucose
yeast cell
polynucleotide
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Japanese (ja)
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JP2006517088A (ja
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ギュンター・ミュラー
ジルケ・ドルーガイ
デルテ・フォス
エックハルト・ボーレス
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サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2004536979A 2002-09-14 2003-09-04 哺乳動物由来のグルコーストランスポーターの発現のための、サッカロミセス・セレビジエＥｒｇ４突然変異体の使用 Expired - Fee Related JP4520854B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10242763A DE10242763A1 (de) 2002-09-14 2002-09-14 Verwendung von Saccharomyces cerevisiae erg4-Mutanten zur Expression von Glukosetransportern aus Säugetieren
PCT/EP2003/009812 WO2004026907A2 (de) 2002-09-14 2003-09-04 Verwendung von saccharomyces cerevisiae erg4-mutanten zur expression von glukosetransportern aus säugetieren

Publications (2)

Publication Number Publication Date
JP2006517088A JP2006517088A (ja) 2006-07-20
JP4520854B2 true JP4520854B2 (ja) 2010-08-11

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JP2004536979A Expired - Fee Related JP4520854B2 (ja) 2002-09-14 2003-09-04 哺乳動物由来のグルコーストランスポーターの発現のための、サッカロミセス・セレビジエＥｒｇ４突然変異体の使用

Country Status (15)

Country Link
EP (1) EP1539958A2 (ru)
JP (1) JP4520854B2 (ru)
KR (1) KR101233998B1 (ru)
CN (1) CN1694960B (ru)
AU (1) AU2003264257B2 (ru)
BR (1) BR0314115A (ru)
CA (1) CA2498636C (ru)
DE (1) DE10242763A1 (ru)
HK (1) HK1084401A1 (ru)
IL (2) IL167321A (ru)
MX (1) MXPA05002816A (ru)
NO (1) NO20051795L (ru)
RU (1) RU2345136C2 (ru)
WO (1) WO2004026907A2 (ru)
ZA (1) ZA200501871B (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102899328A (zh) * 2012-09-28 2013-01-30 南京农业大学 山羊葡萄糖转运载体4基因及其重组表达载体和应用
CN110408616B (zh) * 2019-07-09 2021-06-15 中南民族大学 GLUT4基因敲除的sgRNA、A549细胞系及其构建方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942398A (en) * 1998-02-26 1999-08-24 Millennium Pharmaceuticals, Inc. Nucleic acid molecules encoding glutx and uses thereof
AU5477500A (en) * 1999-06-09 2000-12-28 General Hospital Corporation, The Method of measuring plasma membrane targeting of glut4
DE10106718A1 (de) * 2001-02-14 2002-09-05 Aventis Pharma Gmbh Hefestamm von Saccharomyces cerevisiae mit funktioneller Expression eines Glut-Transporters

Also Published As

Publication number Publication date
EP1539958A2 (de) 2005-06-15
WO2004026907A2 (de) 2004-04-01
ZA200501871B (en) 2005-10-26
CN1694960A (zh) 2005-11-09
AU2003264257B2 (en) 2010-05-20
KR20050056206A (ko) 2005-06-14
BR0314115A (pt) 2005-07-12
RU2005110955A (ru) 2006-01-20
KR101233998B1 (ko) 2013-02-18
CA2498636A1 (en) 2004-04-01
CN1694960B (zh) 2010-05-12
CA2498636C (en) 2012-04-17
WO2004026907A3 (de) 2004-11-11
MXPA05002816A (es) 2005-05-27
IL197621A0 (en) 2011-08-01
DE10242763A1 (de) 2004-03-18
RU2345136C2 (ru) 2009-01-27
JP2006517088A (ja) 2006-07-20
IL197621A (en) 2014-01-30
IL167321A (en) 2013-11-28
HK1084401A1 (en) 2006-07-28
NO20051795L (no) 2005-06-08
AU2003264257A1 (en) 2004-04-08

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