JP4484515B2 - 神経病症候群の治療の為のpde−4阻害剤としての、4−(4−アルコキシ−3−ヒドロキシフェニル)−2−ピロリディン誘導体。 - Google Patents

神経病症候群の治療の為のpde−4阻害剤としての、4−(4−アルコキシ−3−ヒドロキシフェニル)−2−ピロリディン誘導体。 Download PDF

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JP4484515B2
JP4484515B2 JP2003535784A JP2003535784A JP4484515B2 JP 4484515 B2 JP4484515 B2 JP 4484515B2 JP 2003535784 A JP2003535784 A JP 2003535784A JP 2003535784 A JP2003535784 A JP 2003535784A JP 4484515 B2 JP4484515 B2 JP 4484515B2
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pyrrolidone
aminocarbonylmethyl
pyridyl
cyclopentyloxy
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JP2005508961A5 (enExample
JP2005508961A (ja
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ルイピング リウ
ビボ マイケル デ
ハンスユルゲン エルンスト ヘス
アレン ホッパー
エリック ケウスター
アショク テヒム
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メモリ ファーマセチカル コーポレーション
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JP2003535784A 2001-10-16 2002-10-16 神経病症候群の治療の為のpde−4阻害剤としての、4−(4−アルコキシ−3−ヒドロキシフェニル)−2−ピロリディン誘導体。 Expired - Fee Related JP4484515B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32931401P 2001-10-16 2001-10-16
PCT/US2002/032834 WO2003032981A1 (en) 2001-10-16 2002-10-16 4-(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidone derivatives as pde-4 inhibitors for the treatment of neurological syndromes

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JP2009205533A Division JP2009286797A (ja) 2001-10-16 2009-09-07 神経病症候群の治療の為のpde−4阻害剤としての、4−(4−アルコキシ−3−ヒドロキシフェニル)−2−ピロリディン誘導体。

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JP2005508961A JP2005508961A (ja) 2005-04-07
JP2005508961A5 JP2005508961A5 (enExample) 2010-03-18
JP4484515B2 true JP4484515B2 (ja) 2010-06-16

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JP2003535784A Expired - Fee Related JP4484515B2 (ja) 2001-10-16 2002-10-16 神経病症候群の治療の為のpde−4阻害剤としての、4−(4−アルコキシ−3−ヒドロキシフェニル)−2−ピロリディン誘導体。
JP2009205533A Pending JP2009286797A (ja) 2001-10-16 2009-09-07 神経病症候群の治療の為のpde−4阻害剤としての、4−(4−アルコキシ−3−ヒドロキシフェニル)−2−ピロリディン誘導体。

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US8153646B2 (en) 2000-08-10 2012-04-10 Dart Neuroscience (Cayman) Ltd. Phosphodiesterase 4 inhibitors for cognitive and motor rehabilitation
DE60140074D1 (de) * 2000-12-14 2009-11-12 Burnham Inst Non-apoptotische formen des zelltods und verfahren zur modulation
ES2334650T3 (es) 2001-10-16 2010-03-15 Memory Pharmaceuticals Corporation Derivados de 4(4-alkoxi-3-hidroxifenil)-2-pirrolidona como inhibidores de pde-4 para el tratamiento de sindromes neurologicos.
US20030157053A1 (en) * 2002-02-19 2003-08-21 Sabina Sperandio Modulators of paraptosis and related methods
US7495016B2 (en) 2002-10-21 2009-02-24 Irm Llc Pyrrolidones with anti-HIV activity
ES2211344B1 (es) * 2002-12-26 2005-10-01 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
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