JP4475943B2 - プロスタグランジン及びそれらの類縁体の製法 - Google Patents

プロスタグランジン及びそれらの類縁体の製法 Download PDF

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Publication number
JP4475943B2
JP4475943B2 JP2003500077A JP2003500077A JP4475943B2 JP 4475943 B2 JP4475943 B2 JP 4475943B2 JP 2003500077 A JP2003500077 A JP 2003500077A JP 2003500077 A JP2003500077 A JP 2003500077A JP 4475943 B2 JP4475943 B2 JP 4475943B2
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formula
compound
group
alkyl
reaction
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Expired - Fee Related
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Japanese (ja)
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JP2005503354A (ja
JP2005503354A5 (enExample
Inventor
ケネス グリーンウッド，アラン
ムシャティ，デレク
ジョージ トンプソン，デビッド
ウィンハム クリソルド，デレク
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レゾリューション ケミカルズ リミテッド
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Publication of JP2005503354A5 publication Critical patent/JP2005503354A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F295/00—Macromolecular compounds obtained by polymerisation using successively different catalyst types without deactivating the intermediate polymer
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2003500077A 2001-05-24 2002-05-24 プロスタグランジン及びそれらの類縁体の製法 Expired - Fee Related JP4475943B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0112699.4A GB0112699D0 (en) 2001-05-24 2001-05-24 Process for the preparation of prostglandins and analogues thereof
PCT/GB2002/002462 WO2002096898A2 (en) 2001-05-24 2002-05-24 Process for the preparation of prostaglandins and analogues thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009278234A Division JP2010053149A (ja) 2001-05-24 2009-12-08 プロスタグランジン及びそれらの類縁体の製法

Publications (3)

Publication Number Publication Date
JP2005503354A JP2005503354A (ja) 2005-02-03
JP2005503354A5 JP2005503354A5 (enExample) 2006-01-05
JP4475943B2 true JP4475943B2 (ja) 2010-06-09

Family

ID=9915243

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2003500077A Expired - Fee Related JP4475943B2 (ja) 2001-05-24 2002-05-24 プロスタグランジン及びそれらの類縁体の製法
JP2009278234A Pending JP2010053149A (ja) 2001-05-24 2009-12-08 プロスタグランジン及びそれらの類縁体の製法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009278234A Pending JP2010053149A (ja) 2001-05-24 2009-12-08 プロスタグランジン及びそれらの類縁体の製法

Country Status (15)

Country Link
US (3) US20040249172A1 (enExample)
EP (2) EP2311820A1 (enExample)
JP (2) JP4475943B2 (enExample)
CN (2) CN1301986C (enExample)
AU (1) AU2002321396B2 (enExample)
BR (1) BR0209984A (enExample)
CA (1) CA2448088A1 (enExample)
GB (1) GB0112699D0 (enExample)
HU (1) HUP0400047A3 (enExample)
IL (1) IL159030A0 (enExample)
NO (1) NO329883B1 (enExample)
NZ (1) NZ529634A (enExample)
SK (1) SK14362003A3 (enExample)
WO (1) WO2002096898A2 (enExample)
ZA (1) ZA200308916B (enExample)

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GB0112699D0 (en) * 2001-05-24 2001-07-18 Resolution Chemicals Ltd Process for the preparation of prostglandins and analogues thereof
US7321057B2 (en) * 2004-08-02 2008-01-22 R-Tech Ueno, Ltd. Method for manufacturing prostaglandin analogue
PL212658B1 (pl) * 2005-04-18 2012-11-30 Inst Farmaceutyczny Sposób otrzymywania pochodnych 13,14-dihydro-PGF<sub>2</sub><sub>α</sub>
US20090287003A1 (en) * 2005-09-29 2009-11-19 Jiang Xing Chen Process for the production of intermediates for making prostaglandin derivatives such as latanaprost, travaprost, and bimatoprost
US7511168B2 (en) 2006-01-18 2009-03-31 Shih-Yi Wei Processes and intermediates for the preparations of prostaglandins
US8546114B2 (en) 2006-01-18 2013-10-01 Chirogate International Inc. Processes for the preparation of optically active cyclopentenones and cyclopentenones prepared therefrom
EP2735566A1 (en) * 2006-02-07 2014-05-28 R-Tech Ueno, Ltd. Method for preparing prostaglandin derivative
JP2008037782A (ja) * 2006-08-04 2008-02-21 Daiichi Fine Chemical Co Ltd プロスタグランジン誘導体の製造方法
US7642370B2 (en) * 2006-08-07 2010-01-05 Daiichi Fine Chemical Co., Ltd. Method for preparing prostaglandin derivative
US20090233830A1 (en) * 2008-03-14 2009-09-17 Penny Sue Dirr Automatic detergent dishwashing composition
EP2135860A1 (en) 2008-06-20 2009-12-23 Sandoz AG Improved process for the production of bimatoprost
EP2143712A1 (en) 2008-07-10 2010-01-13 Sandoz AG Improved Process for the Production of Prostaglandins and Prostaglandin Analogs
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US8519178B2 (en) * 2009-06-22 2013-08-27 Johnson Matthey Public Limited Company Method for the purification of prostaglandins
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WO2011055377A1 (en) * 2009-11-05 2011-05-12 Biocon Limited A novel process for the preparation of prostaglandins and intermediates thereof
WO2011095990A2 (en) 2010-02-03 2011-08-11 Fdc Limited Process for the purification of prostaglandins and analogues thereof
EP2495235B1 (en) 2011-03-04 2015-08-05 Newchem S.p.A. Process for the synthesis of prostaglandins and intermediates thereof
HU231203B1 (hu) * 2011-12-21 2021-10-28 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Új eljárás travoprost előállítására
TWI435752B (zh) * 2012-08-15 2014-05-01 Everlight Chem Ind Corp 使用製備型高效液相層析儀純化含氟之前列腺素之方法
US9115109B2 (en) 2013-08-15 2015-08-25 Chirogate International Inc. Processes and intermediates for the preparations of isomer free prostaglandins
HU231214B1 (hu) 2014-03-13 2021-11-29 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Új eljárás nagytisztaságú prosztaglandinok előállítására
CN104513186B (zh) * 2015-01-13 2016-10-05 宁波第二激素厂 一种光学纯的右旋氯前列醇钠的制备方法
HU231175B1 (hu) * 2015-12-04 2021-06-28 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Tetszőleges, előre meghatározott minőségű Latanoprostene bunod előállítása gravitációs kromatográfiával
EP3950672A4 (en) * 2019-03-27 2023-01-11 Kyowa Pharma Chemical Co., Ltd. PROCESS FOR PRODUCTION OF PROSTAGLANDIN
CN112608294B (zh) * 2020-12-16 2021-10-26 西安国康瑞金制药有限公司 一种拉坦前列腺素的制备方法
WO2022138586A1 (ja) * 2020-12-23 2022-06-30 協和ファーマケミカル株式会社 幾何異性体の分離方法
CN115991691B (zh) * 2023-03-23 2023-05-16 西南交通大学 一种拉坦前列素中间体的制备方法及其用途
WO2025149165A1 (en) 2024-01-12 2025-07-17 Intervet International B.V. A PROCESS FOR PURIFICATION OF INTERMEDIATES OF PROSTAGLANDIN F2Αα COMPOUNDS AND ITS USE IN THE PREPARATION OF PROSTAGLANDIN F2α COMPOUNDS

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Also Published As

Publication number Publication date
JP2010053149A (ja) 2010-03-11
US20050272877A1 (en) 2005-12-08
GB0112699D0 (en) 2001-07-18
US7268239B2 (en) 2007-09-11
AU2002321396B2 (en) 2007-10-18
CA2448088A1 (en) 2002-12-05
BR0209984A (pt) 2004-04-06
WO2002096898A3 (en) 2003-03-20
JP2005503354A (ja) 2005-02-03
NZ529634A (en) 2004-11-26
CN1533385A (zh) 2004-09-29
ZA200308916B (en) 2007-11-28
US7498458B2 (en) 2009-03-03
WO2002096898A2 (en) 2002-12-05
US20040249172A1 (en) 2004-12-09
NO329883B1 (no) 2011-01-17
SK14362003A3 (sk) 2004-05-04
CN101003503A (zh) 2007-07-25
HUP0400047A3 (en) 2007-05-02
EP1389198A2 (en) 2004-02-18
NO20035162D0 (no) 2003-11-20
US20050261374A1 (en) 2005-11-24
HUP0400047A2 (hu) 2004-04-28
IL159030A0 (en) 2004-05-12
EP2311820A1 (en) 2011-04-20
CN1301986C (zh) 2007-02-28

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