IT1392492B1 - Processo per la purificazione del latanoprost, analogo sintetico della prostaglandina pgf2alfa. - Google Patents

Processo per la purificazione del latanoprost, analogo sintetico della prostaglandina pgf2alfa.

Info

Publication number
IT1392492B1
IT1392492B1 ITMI2008A002330A ITMI20082330A IT1392492B1 IT 1392492 B1 IT1392492 B1 IT 1392492B1 IT MI2008A002330 A ITMI2008A002330 A IT MI2008A002330A IT MI20082330 A ITMI20082330 A IT MI20082330A IT 1392492 B1 IT1392492 B1 IT 1392492B1
Authority
IT
Italy
Prior art keywords
latanoprost
purification
pgf2alfa
prostaglandina
synthetic analogue
Prior art date
Application number
ITMI2008A002330A
Other languages
English (en)
Inventor
Francesca Costantino
Brisco Roberto Di
Original Assignee
Ind Chimica Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind Chimica Srl filed Critical Ind Chimica Srl
Priority to ITMI2008A002330A priority Critical patent/IT1392492B1/it
Priority to EP09180333A priority patent/EP2208724B1/en
Priority to AT09180333T priority patent/ATE536341T1/de
Publication of ITMI20082330A1 publication Critical patent/ITMI20082330A1/it
Priority to HK11100478.8A priority patent/HK1146267A1/xx
Application granted granted Critical
Publication of IT1392492B1 publication Critical patent/IT1392492B1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
ITMI2008A002330A 2008-12-24 2008-12-24 Processo per la purificazione del latanoprost, analogo sintetico della prostaglandina pgf2alfa. IT1392492B1 (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ITMI2008A002330A IT1392492B1 (it) 2008-12-24 2008-12-24 Processo per la purificazione del latanoprost, analogo sintetico della prostaglandina pgf2alfa.
EP09180333A EP2208724B1 (en) 2008-12-24 2009-12-22 Process for purification of latanoprost, synthetic analogue of prostaglandin PGF 2alfa
AT09180333T ATE536341T1 (de) 2008-12-24 2009-12-22 Verfahren zur reinigung von latanoprost
HK11100478.8A HK1146267A1 (en) 2008-12-24 2011-01-18 Process for purification of latanoprost, synthetic analogue of prostaglandin pgf 2alfa

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI2008A002330A IT1392492B1 (it) 2008-12-24 2008-12-24 Processo per la purificazione del latanoprost, analogo sintetico della prostaglandina pgf2alfa.

Publications (2)

Publication Number Publication Date
ITMI20082330A1 ITMI20082330A1 (it) 2010-06-25
IT1392492B1 true IT1392492B1 (it) 2012-03-09

Family

ID=41171094

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI2008A002330A IT1392492B1 (it) 2008-12-24 2008-12-24 Processo per la purificazione del latanoprost, analogo sintetico della prostaglandina pgf2alfa.

Country Status (4)

Country Link
EP (1) EP2208724B1 (it)
AT (1) ATE536341T1 (it)
HK (1) HK1146267A1 (it)
IT (1) IT1392492B1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU231214B1 (hu) 2014-03-13 2021-11-29 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Új eljárás nagytisztaságú prosztaglandinok előállítására
CN112832150B (zh) * 2021-01-27 2022-06-24 中交第三公路工程局有限公司 一种涵洞通道等立面垂直凿毛装置
CN115322095A (zh) * 2021-01-27 2022-11-11 Agc株式会社 他氟前列素的纯化方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1224935A3 (en) 1988-09-06 2003-03-26 Pharmacia Aktiebolag Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
HU212570B (en) 1991-06-24 1996-08-29 Chinoin Gyogyszer Es Vegyeszet Process for producing 13,14-dihydro-15(r)-17-phenyl-18,19,20-trinor-pgf2alfa-isopropylester
IL134241A (en) 2000-01-27 2006-06-11 Finetech Pharmaceutical Ltd Process for the preparation of latanoprost
GB0112699D0 (en) * 2001-05-24 2001-07-18 Resolution Chemicals Ltd Process for the preparation of prostglandins and analogues thereof
EP1406854A1 (en) 2001-07-17 2004-04-14 PHARMACIA & UPJOHN COMPANY Process and intermediates to prepare latanoprost
PL212658B1 (pl) * 2005-04-18 2012-11-30 Inst Farmaceutyczny Sposób otrzymywania pochodnych 13,14-dihydro-PGF<sub>2</sub><sub>α</sub>
ITRM20050231A1 (it) 2005-05-13 2006-11-14 Technopharma Sa Procedimento per la sintesi di derivati delle prostaglandine f.

Also Published As

Publication number Publication date
HK1146267A1 (en) 2011-05-27
ATE536341T1 (de) 2011-12-15
EP2208724A1 (en) 2010-07-21
ITMI20082330A1 (it) 2010-06-25
EP2208724B1 (en) 2011-12-07

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