JP4407271B2 - チップ、反応分析装置、反応分析方法 - Google Patents

チップ、反応分析装置、反応分析方法 Download PDF

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Publication number
JP4407271B2
JP4407271B2 JP2003421957A JP2003421957A JP4407271B2 JP 4407271 B2 JP4407271 B2 JP 4407271B2 JP 2003421957 A JP2003421957 A JP 2003421957A JP 2003421957 A JP2003421957 A JP 2003421957A JP 4407271 B2 JP4407271 B2 JP 4407271B2
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substrate
flow path
liquid
chip
intermediate member
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Japanese (ja)
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JP2005181095A (ja
JP2005181095A5 (enExample
Inventor
啓 竹中
徹 藤村
康 後藤
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Hitachi Ltd
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Hitachi Ltd
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Priority to JP2003421957A priority Critical patent/JP4407271B2/ja
Priority to US10/931,064 priority patent/US7311881B2/en
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Publication of JP2005181095A5 publication Critical patent/JP2005181095A5/ja
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optical Measuring Cells (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2003421957A 2003-12-19 2003-12-19 チップ、反応分析装置、反応分析方法 Expired - Fee Related JP4407271B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2003421957A JP4407271B2 (ja) 2003-12-19 2003-12-19 チップ、反応分析装置、反応分析方法
US10/931,064 US7311881B2 (en) 2003-12-19 2004-09-01 Chips, and apparatus and method for reaction analysis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003421957A JP4407271B2 (ja) 2003-12-19 2003-12-19 チップ、反応分析装置、反応分析方法

Publications (3)

Publication Number Publication Date
JP2005181095A JP2005181095A (ja) 2005-07-07
JP2005181095A5 JP2005181095A5 (enExample) 2006-07-13
JP4407271B2 true JP4407271B2 (ja) 2010-02-03

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US (1) US7311881B2 (enExample)
JP (1) JP4407271B2 (enExample)

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EP1697719B1 (en) * 2003-12-23 2018-09-19 Ventana Medical Systems, Inc. Method and apparatus for efficient thin film fluid processing of flat surfaces
WO2006057358A1 (ja) * 2004-11-25 2006-06-01 The Furukawa Electric Co., Ltd. ファイバセンサ、ファイバセンサ装置
JP4654119B2 (ja) * 2005-11-29 2011-03-16 東京エレクトロン株式会社 塗布・現像装置及び塗布・現像方法
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JP4685691B2 (ja) * 2006-04-13 2011-05-18 株式会社日立ソリューションズ 検査チップ及び検査チップシステム
JP4941119B2 (ja) * 2006-07-14 2012-05-30 セントラル硝子株式会社 ヒートパイプ
JP5062399B2 (ja) * 2007-02-19 2012-10-31 セイコーインスツル株式会社 マイクロ流路およびマイクロリアクタ
CN101842690B (zh) * 2007-10-29 2013-06-26 皇家飞利浦电子股份有限公司 受抑全内反射生物传感器盒
KR20110016479A (ko) * 2008-06-06 2011-02-17 바이오나노매트릭스, 인크. 통합 나노유체 분석 장치, 제작 방법 및 분석 기술
JP5167194B2 (ja) * 2009-04-28 2013-03-21 株式会社日立エンジニアリング・アンド・サービス 微生物検査装置
ITTO20100068U1 (it) * 2010-04-20 2011-10-21 Eltek Spa Dispositivi microfluidici e/o attrezzature per dispositivi microfluidici
US9103787B2 (en) 2010-05-25 2015-08-11 Stmicroelectronics S.R.L. Optically accessible microfluidic diagnostic device
WO2012061818A1 (en) * 2010-11-05 2012-05-10 Life Technologies Corporation Flowcells and flowcell reaction chambers
JP5553014B2 (ja) * 2010-11-26 2014-07-16 コニカミノルタ株式会社 分析チップのプリズム部、このプリズム部を含む分析チップ、及び分析チップのプリズム部の製造方法
JP2013075984A (ja) * 2011-09-30 2013-04-25 Toshiba Corp 微細構造体の製造方法
ES2459269B1 (es) * 2012-10-04 2015-03-24 Universidad De Zaragoza Dispositivo y método de encapsulado de sistemas microfluídicos
JP6366226B2 (ja) * 2013-05-24 2018-08-01 株式会社島津製作所 マイクロチップ反応装置
JP2014235115A (ja) 2013-06-04 2014-12-15 ウシオ電機株式会社 マイクロチップおよびマイクロチップにおける金属薄膜の成膜方法
JP6234768B2 (ja) * 2013-10-21 2017-11-22 日東電工株式会社 光導波路ならびに該光導波路を用いたｓｐｒセンサセルおよび比色センサセル
WO2015063540A1 (es) * 2013-10-28 2015-05-07 Droguett Bizet Sara Micro dispositivo tipo lab-on-chip para identificar la sensibilidad antibiótica en el punto de atencion de los pacientes
EP4026616B1 (en) * 2015-08-26 2024-12-11 Emulate, Inc. Perfusion manifold assembly
CN108602064B (zh) * 2015-10-23 2021-06-29 国家科学研究中心 用于控制活体几何形状的微米流体装置
CN108118088B (zh) * 2016-11-28 2021-08-27 中国科学院大连化学物理研究所 一种基于微流控芯片的人y-str基因位点分型方法
JP6931540B2 (ja) 2017-02-27 2021-09-08 シスメックス株式会社 検体処理チップを用いた送液方法、検体処理チップの送液装置
US10429629B1 (en) * 2017-04-18 2019-10-01 Veily Life Sciences LLC Imaging and side-scatter photon detection using a single immersion objective
ES2694172A1 (es) * 2017-06-16 2018-12-18 Universidad De Zaragoza Dispositivo de encapsulado apto para aplicaciones microfluídicas
US11287404B2 (en) * 2017-12-21 2022-03-29 International Business Machines Corporation Analysis apparatus with spectrometer
WO2019147897A1 (en) * 2018-01-26 2019-08-01 Qiagen Gmbh Sequencing flowcells
CN108535241A (zh) * 2018-05-22 2018-09-14 中国科学院武汉病毒研究所 一种快速免疫检测装置及其应用
CN111889150B (zh) * 2020-07-01 2021-07-13 西安交通大学 Atp荧光微流控芯片、生物发光连续检测系统和检测方法
CN113484411A (zh) * 2021-07-14 2021-10-08 武汉洛特福动力技术有限公司 一种尿素超声波传感器
CN116786180B (zh) * 2023-04-04 2025-07-08 苏州聚阳环保科技股份有限公司 TiO2光电催化氧化法测量COD的微流控芯片及其制备办法
WO2024247692A1 (ja) * 2023-05-29 2024-12-05 富士フイルム株式会社 ノズル

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US20050136685A1 (en) 2005-06-23
JP2005181095A (ja) 2005-07-07
US7311881B2 (en) 2007-12-25

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