JP4372837B2 - 核酸配列増幅 - Google Patents

核酸配列増幅 Download PDF

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Publication number
JP4372837B2
JP4372837B2 JP50543394A JP50543394A JP4372837B2 JP 4372837 B2 JP4372837 B2 JP 4372837B2 JP 50543394 A JP50543394 A JP 50543394A JP 50543394 A JP50543394 A JP 50543394A JP 4372837 B2 JP4372837 B2 JP 4372837B2
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JP
Japan
Prior art keywords
oligonucleotide
sequence
primer
target
promoter
Prior art date
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Expired - Fee Related
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JP50543394A
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English (en)
Japanese (ja)
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JPH07509368A (ja
Inventor
マクドノウ、シェロル・エイチ
カシアン、ダニエル・エル
ダッタグプタ、ナニブフシャ
マカリスター、ダイアン・エル
ハモンド、フィリップ・ダブリュー
ライダー、トマス・ビー
イーシング・ワイ・ヤング
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Gen Probe Inc
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Gen Probe Inc
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Publication of JPH07509368A publication Critical patent/JPH07509368A/ja
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Publication of JP4372837B2 publication Critical patent/JP4372837B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP50543394A 1992-08-04 1993-07-28 核酸配列増幅 Expired - Fee Related JP4372837B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92540592A 1992-08-04 1992-08-04
US925,405 1992-08-04
PCT/US1993/007138 WO1994003472A1 (en) 1992-08-04 1993-07-28 Nucleic acid sequence amplification

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2003433721A Division JP3860809B2 (ja) 1992-08-04 2003-12-26 核酸配列増幅

Publications (2)

Publication Number Publication Date
JPH07509368A JPH07509368A (ja) 1995-10-19
JP4372837B2 true JP4372837B2 (ja) 2009-11-25

Family

ID=25451694

Family Applications (3)

Application Number Title Priority Date Filing Date
JP50543394A Expired - Fee Related JP4372837B2 (ja) 1992-08-04 1993-07-28 核酸配列増幅
JP2003433721A Expired - Lifetime JP3860809B2 (ja) 1992-08-04 2003-12-26 核酸配列増幅
JP2006131455A Pending JP2006238892A (ja) 1992-08-04 2006-05-10 核酸配列増幅

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2003433721A Expired - Lifetime JP3860809B2 (ja) 1992-08-04 2003-12-26 核酸配列増幅
JP2006131455A Pending JP2006238892A (ja) 1992-08-04 2006-05-10 核酸配列増幅

Country Status (11)

Country Link
EP (2) EP0587298B1 (enExample)
JP (3) JP4372837B2 (enExample)
KR (1) KR100316498B1 (enExample)
AT (2) ATE346954T1 (enExample)
AU (2) AU670116B2 (enExample)
CA (1) CA2141430C (enExample)
DE (2) DE69329636T2 (enExample)
ES (1) ES2277679T3 (enExample)
NO (1) NO950381L (enExample)
TW (1) TW278099B (enExample)
WO (1) WO1994003472A1 (enExample)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981179A (en) * 1991-11-14 1999-11-09 Digene Diagnostics, Inc. Continuous amplification reaction
DE69431240T2 (de) * 1993-12-01 2003-04-17 Toyo Boseki K.K., Osaka Verfahren zur ampflifizierung und zum nachweis bestimmter nukleinsäuresequenzen mittels thermostabiler enzyme
FR2724934B1 (fr) * 1994-09-26 1997-01-24 Bio Merieux Oligonucleotide chimere et son utilisation dans l'obtention de transcrits d'un acide nucleique
US5514551A (en) * 1994-10-14 1996-05-07 Gen-Probe Incorporated Compositions for the detection of Chlamydia trachomatis
ATE194391T1 (de) * 1995-01-19 2000-07-15 Gen Probe Inc Amplifikationsoligonukleotide und sonden für borrelia, die mit lyme kranheit assoziiert sind
US5622827A (en) * 1995-02-07 1997-04-22 Gen-Probe Incorporated Amplification primers and nucleic acid probes targeted to coccidioides immitis nucleic acid
EP0826066B1 (en) 1995-05-05 2000-09-13 The Perkin-Elmer Corporation Methods and reagents for combined pcr amplification and hybridization probing assay
US5925518A (en) * 1995-05-19 1999-07-20 Akzo Nobel N.V. Nucleic acid primers for amplification of a mycobacteria RNA template
US5916777A (en) * 1995-06-07 1999-06-29 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using 3'-ribonucleotide primers
AU707691B2 (en) * 1995-06-07 1999-07-15 Gen-Probe Incorporated Nucleic acid probes and amplification oligonucleotides for neisseria species
US5652126A (en) * 1995-06-07 1997-07-29 Gen-Probe Incorporated Use of restriction endonuclease sequences for cleaving phosphorothioate oligonucleotides
US5747252A (en) * 1995-06-07 1998-05-05 Gen-Probe Incorporated Nucleic acid probes and amplification oligonucleotides for Neisseria species
US5882857A (en) * 1995-06-07 1999-03-16 Behringwerke Ag Internal positive controls for nucleic acid amplification
CA2223241C (en) * 1995-06-07 2009-11-17 Gen-Probe Incorporated Methods and kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US5932450A (en) * 1995-06-07 1999-08-03 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using digestible templates
US5710029A (en) * 1995-06-07 1998-01-20 Gen-Probe Incorporated Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US5705365A (en) * 1995-06-07 1998-01-06 Gen-Probe Incorporated Kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US5739311A (en) * 1995-06-07 1998-04-14 Gen-Probe Incorporated Enzymatic synthesis of phosphorothioate oligonucleotides using restriction endonucleases
DE69734576T2 (de) * 1996-03-01 2006-08-03 E.I. Dupont De Nemours And Co., Wilmington Methode zur vervielfältigung und zum nachweis eines gewünschten nukleinsäurefragments
WO1997044488A2 (en) 1996-05-22 1997-11-27 Gen-Probe Incorporated Compositions and methods for the detection of mycobacterium kansasii
US6013488A (en) * 1996-07-25 2000-01-11 The Institute Of Physical And Chemical Research Method for reverse transcription
US6057134A (en) * 1996-10-07 2000-05-02 Ambion, Inc. Modulating the efficiency of nucleic acid amplification reactions with 3' modified oligonucleotides
WO1998022625A1 (en) 1996-11-20 1998-05-28 The Regents Of The University Of Michigan Microfabricated isothermal nucleic acid amplification devices and methods
GB9626074D0 (en) 1996-12-16 1997-02-05 Cytocell Ltd Nucleic acids amplification assay
US6025133A (en) * 1996-12-30 2000-02-15 Gen-Probe Incorporated Promoter-sequestered oligonucleoside and method of use
US6534273B2 (en) 1997-05-02 2003-03-18 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
DK0975807T3 (da) * 1997-05-02 2007-01-29 Gen Probe Inc To-trins hybridisering og indfangning af et polynukleotid
WO1999009213A1 (en) * 1997-08-14 1999-02-25 Takara Shuzo Co., Ltd. Methods for dna amplification and kits therefor
JP2002509443A (ja) * 1997-10-31 2002-03-26 ジェン−プローブ・インコーポレーテッド 核酸検出法
US5932451A (en) * 1997-11-19 1999-08-03 Incyte Pharmaceuticals, Inc. Method for unbiased mRNA amplification
JP4438110B2 (ja) * 1998-07-01 2010-03-24 東ソー株式会社 標的核酸の定量方法
AU4739600A (en) * 1999-05-17 2000-12-05 Mcgill University Method for subtracting cdnas by suppressing the synthesis of specifically targeted mrnas
DE60022541T2 (de) 1999-07-23 2006-06-14 Gen Probe Inc Polynukleotid- amplifikationsverfahren
US6902891B2 (en) 1999-12-17 2005-06-07 Bio Merieux Process for labeling a nucleic acid
US6489114B2 (en) 1999-12-17 2002-12-03 Bio Merieux Process for labeling a ribonucleic acid, and labeled RNA fragments which are obtained thereby
JP2002051778A (ja) * 2000-05-31 2002-02-19 Tosoh Corp 小型球形ウイルス（ｓｒｓｖ）ｒｎａ検出のためのオリゴヌクレオチドおよび検出法
AU2001291513B2 (en) * 2000-10-03 2007-06-07 Id+Plus Ltd Nucleotide detection method
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WO2002034951A2 (en) 2000-10-23 2002-05-02 Gen-Probe Incorporated Compositions and methods for detecting human immunodeficiency virus 2 (hiv-2)
JP2002125688A (ja) * 2000-10-30 2002-05-08 Tosoh Corp Ｃ型肝炎ウイルスの高感度検出のためのオリゴヌクレオチドおよび検出法
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AU2003253651C1 (en) 2002-06-14 2010-06-03 Gen-Probe Incorporated Compositions and methods for detecting hepatitis B virus
EP2366803B8 (en) 2002-10-16 2015-08-19 Gen-Probe Incorporated Compositions and methods for detecting west nile virus
ES2383947T3 (es) 2003-12-19 2012-06-27 Gen-Probe Incorporated Composiciones, métodos y equipos para la detección de ácidos nucleicos del vih-1 y vih-2
WO2006039564A2 (en) 2004-09-30 2006-04-13 Gen-Probe Incorporated Assay for detecting and quantifying hiv-1
WO2006137939A2 (en) 2004-11-09 2006-12-28 Gen-Probe Incorporated Compositions and methods for detecting group a streptococci
WO2006089154A1 (en) 2005-02-18 2006-08-24 Gen-Probe Incorporated Sample preparation method incorporating an alkaline shock
EP1877418B1 (en) 2005-05-06 2013-11-20 Gen-Probe Incorporated Compositions and assays to detect influenza virus a nucleic acids
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WO2007140279A2 (en) * 2006-05-24 2007-12-06 Gen-Probe Incorporated Probes and kits for determining the presence of mycobacterium tuberculosis complex organisms in a test sample and method of amplifying gram-positive bacteria and fungi employing capture probe
EP1921156A1 (en) 2006-11-10 2008-05-14 bioMerieux B.V. Improved multiplex nucleic acid amplification using blocked primers
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
EP1978111B1 (en) * 2007-04-02 2013-03-27 Gen-Probe Incorporated Compositions, kits and related methods for the detection and/or monitoring of Pseudomonas aeruginosa
EP2281070B1 (en) 2008-04-21 2015-01-21 Gen-Probe Incorporated Method for detecting chikungunya virus
EP3118208A1 (en) 2009-02-26 2017-01-18 Gen-Probe Incorporated Assay for detection of human parvovirus nuleic acid
WO2012009373A2 (en) 2010-07-12 2012-01-19 Gen-Probe Incorporated Compositions and assays to detect swine h1n1 influenza a virus, seasonal h1 influenza a virus and seasonal h3 influenza a virus nucleic acids
WO2012030856A2 (en) 2010-08-30 2012-03-08 Gen-Probe Incorporated Compositions, methods and reaction mixtures for the detection of xenotropic murine leukemia virus-related virus
EP3536810B1 (en) 2011-07-15 2023-05-10 Gen-Probe Incorporated Compositions and method for detecting human parvovirus nucleic acid and hepatitis a virus nucleic acid
EP2877952B1 (en) 2012-07-27 2023-04-12 Gen-Probe Incorporated Dual reference calibration method and system for quantifying polynucleotides
US9976175B2 (en) 2013-03-15 2018-05-22 Gen-Probe Incorporated Calibration method, apparatus and computer program product
AU2018237578B2 (en) 2017-03-24 2024-03-07 Gen-Probe Incorporated Compositions and methods for detecting or quantifying Parainfluenza virus
EP4212634A1 (en) 2017-03-24 2023-07-19 Gen-Probe Incorporated Compositions and methods for detection of flu b in samples
US11859257B2 (en) 2017-08-11 2024-01-02 Gen-Probe Incorporated Compositions and methods for detecting Staphylococcus aureus
JP2021506274A (ja) 2017-12-15 2021-02-22 ジェン−プローブ・インコーポレーテッド 毒素産生Ｃｌｏｓｔｒｉｄｉｕｍ ｄｉｆｆｉｃｉｌｅを検出するための組成物および方法
GB2597566B (en) 2018-06-13 2023-02-01 Gen Probe Inc Compositions and methods for detecting group B streptococcus nucleic acid
US12227812B2 (en) 2018-08-01 2025-02-18 Gen-Probe Incorporated Compositions and methods for detecting nucleic acids of Epstein-Barr virus
AU2019319203B8 (en) 2018-08-08 2025-10-09 Gen-Probe Incorporated Compositions, methods and kits for detecting Mycoplasma genitalium
AU2019326462B2 (en) 2018-08-21 2025-11-27 Gen-Probe Incorporated Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus
AU2019350777B2 (en) 2018-09-27 2025-11-27 Gen-Probe Incorporated Compositions and methods for detecting Bordetella pertussis and Bordetellaparapertussis nucleic acid
WO2020086546A1 (en) 2018-10-22 2020-04-30 Gen-Probe Incorporated Compositions and methods for amplifying, detecting or quantifying human polyomavirus bk virus
EP4018004B1 (en) 2019-08-23 2025-06-18 Gen-Probe Incorporated Compositions, methods and kits for detecting treponema pallidum
US20220333162A1 (en) 2019-09-05 2022-10-20 Gen-Probe Incorporated Detection of chlamydia trachomatis nucleic acid variants
AU2020402029B2 (en) 2019-12-09 2022-12-15 Gen-Probe Incorporated Quantification of polynucleotide analytes from dried samples
CA3174532A1 (en) 2020-03-04 2021-09-10 Gen-Probe Incorporated Compositions and methods for detecting sars-cov-2 nucleic acid
WO2023010008A1 (en) 2021-07-27 2023-02-02 Gen-Probe Incorporated Compositions and methods for detecting gastrointestinal pathogens
KR102544380B1 (ko) 2022-01-29 2023-06-16 (주)동방지퍼 지퍼용 슬라이더와 손잡이의 결착방법 및 이로 인해 제조된 지퍼
EP4282980A1 (en) 2022-05-23 2023-11-29 Mobidiag Oy Methods for amplifying a nucleic acid
WO2024054924A1 (en) 2022-09-08 2024-03-14 Gen-Probe Incorporated Method of detecting nucleic acid analytes using dual-specificity primers
AU2024267362A1 (en) 2023-05-05 2025-11-13 Gen-Probe Incorporated Method and system for improving specificity of analyte detection using real-time nucleic acid amplification

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Also Published As

Publication number Publication date
KR100316498B1 (ko) 2002-06-20
JP2006238892A (ja) 2006-09-14
ATE346954T1 (de) 2006-12-15
DE69329636D1 (de) 2000-12-14
AU6802796A (en) 1996-12-19
ATE197479T1 (de) 2000-11-11
EP0587298A2 (en) 1994-03-16
DE69334092D1 (de) 2007-01-11
WO1994003472A1 (en) 1994-02-17
EP0978570A2 (en) 2000-02-09
KR950702999A (ko) 1995-08-23
EP0978570B1 (en) 2006-11-29
JPH07509368A (ja) 1995-10-19
AU670116B2 (en) 1996-07-04
AU4792093A (en) 1994-03-03
EP0587298B1 (en) 2000-11-08
JP2004194662A (ja) 2004-07-15
DE69334092T2 (de) 2007-07-05
CA2141430C (en) 2009-05-12
EP0587298A3 (en) 1995-08-30
EP0978570A3 (en) 2000-04-12
NO950381D0 (no) 1995-02-02
ES2277679T3 (es) 2007-07-16
AU700253B2 (en) 1998-12-24
CA2141430A1 (en) 1994-02-17
TW278099B (enExample) 1996-06-11
NO950381L (no) 1995-04-03
DE69329636T2 (de) 2001-03-01
JP3860809B2 (ja) 2006-12-20

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