ATE346954T1 - Nachweis von mycobacterium tuberculosis durch vervielfältigung von nukleinsäuresequenzen - Google Patents

Nachweis von mycobacterium tuberculosis durch vervielfältigung von nukleinsäuresequenzen

Info

Publication number
ATE346954T1
ATE346954T1 AT99121906T AT99121906T ATE346954T1 AT E346954 T1 ATE346954 T1 AT E346954T1 AT 99121906 T AT99121906 T AT 99121906T AT 99121906 T AT99121906 T AT 99121906T AT E346954 T1 ATE346954 T1 AT E346954T1
Authority
AT
Austria
Prior art keywords
duplication
detection
nucleic acid
acid sequences
mycobacterium tuberculosis
Prior art date
Application number
AT99121906T
Other languages
English (en)
Inventor
Diane L Mcallister
Philip W Hammond
Y Yang Yeasing
Sherrol Mcdonough
Daniel Kacian
Nanibhushan Dattagupta
Thomas B Ryder
Original Assignee
Gen Probe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Application granted granted Critical
Publication of ATE346954T1 publication Critical patent/ATE346954T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT99121906T 1992-08-04 1993-08-04 Nachweis von mycobacterium tuberculosis durch vervielfältigung von nukleinsäuresequenzen ATE346954T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92540592A 1992-08-04 1992-08-04

Publications (1)

Publication Number Publication Date
ATE346954T1 true ATE346954T1 (de) 2006-12-15

Family

ID=25451694

Family Applications (2)

Application Number Title Priority Date Filing Date
AT99121906T ATE346954T1 (de) 1992-08-04 1993-08-04 Nachweis von mycobacterium tuberculosis durch vervielfältigung von nukleinsäuresequenzen
AT93306169T ATE197479T1 (de) 1992-08-04 1993-08-04 Verfahren zur vervielfältigung von nukleinsäuresequenzen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT93306169T ATE197479T1 (de) 1992-08-04 1993-08-04 Verfahren zur vervielfältigung von nukleinsäuresequenzen

Country Status (11)

Country Link
EP (2) EP0978570B1 (de)
JP (3) JP4372837B2 (de)
KR (1) KR100316498B1 (de)
AT (2) ATE346954T1 (de)
AU (2) AU670116B2 (de)
CA (1) CA2141430C (de)
DE (2) DE69329636T2 (de)
ES (1) ES2277679T3 (de)
NO (1) NO950381L (de)
TW (1) TW278099B (de)
WO (1) WO1994003472A1 (de)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981179A (en) * 1991-11-14 1999-11-09 Digene Diagnostics, Inc. Continuous amplification reaction
WO1995015399A1 (fr) * 1993-12-01 1995-06-08 Toyo Boseki Kabushiki Kaisha Procede d'amplification et de detection d'une sequence nucleotidique au moyen d'enzymes thermostables
FR2724934B1 (fr) * 1994-09-26 1997-01-24 Bio Merieux Oligonucleotide chimere et son utilisation dans l'obtention de transcrits d'un acide nucleique
US5514551A (en) * 1994-10-14 1996-05-07 Gen-Probe Incorporated Compositions for the detection of Chlamydia trachomatis
ES2150103T3 (es) * 1995-01-19 2000-11-16 Gen Probe Inc Oligonucleotidos de amplificacion de acido nucleico y sondas para borrelia asociados con la enfermedad de lyme.
US5622827A (en) * 1995-02-07 1997-04-22 Gen-Probe Incorporated Amplification primers and nucleic acid probes targeted to coccidioides immitis nucleic acid
ATE196322T1 (de) 1995-05-05 2000-09-15 Perkin Elmer Corp Methoden and reagentien fuer die kombination einer pcr-amplifizierung mit einem hybridisierungs-assay
US5925518A (en) * 1995-05-19 1999-07-20 Akzo Nobel N.V. Nucleic acid primers for amplification of a mycobacteria RNA template
US5652126A (en) * 1995-06-07 1997-07-29 Gen-Probe Incorporated Use of restriction endonuclease sequences for cleaving phosphorothioate oligonucleotides
US5747252A (en) * 1995-06-07 1998-05-05 Gen-Probe Incorporated Nucleic acid probes and amplification oligonucleotides for Neisseria species
AU707691B2 (en) * 1995-06-07 1999-07-15 Gen-Probe Incorporated Nucleic acid probes and amplification oligonucleotides for neisseria species
US5705365A (en) * 1995-06-07 1998-01-06 Gen-Probe Incorporated Kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
CA2223241C (en) * 1995-06-07 2009-11-17 Gen-Probe Incorporated Methods and kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US5882857A (en) * 1995-06-07 1999-03-16 Behringwerke Ag Internal positive controls for nucleic acid amplification
US5916777A (en) * 1995-06-07 1999-06-29 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using 3'-ribonucleotide primers
US5739311A (en) * 1995-06-07 1998-04-14 Gen-Probe Incorporated Enzymatic synthesis of phosphorothioate oligonucleotides using restriction endonucleases
US5932450A (en) * 1995-06-07 1999-08-03 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using digestible templates
US5710029A (en) * 1995-06-07 1998-01-20 Gen-Probe Incorporated Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
DE69734576T2 (de) * 1996-03-01 2006-08-03 E.I. Dupont De Nemours And Co., Wilmington Methode zur vervielfältigung und zum nachweis eines gewünschten nukleinsäurefragments
US6218107B1 (en) 1996-05-22 2001-04-17 Gen-Probe Incorporated Compositions and methods for detecting the presence of Mycobacterium kansassii
US6013488A (en) * 1996-07-25 2000-01-11 The Institute Of Physical And Chemical Research Method for reverse transcription
US6057134A (en) * 1996-10-07 2000-05-02 Ambion, Inc. Modulating the efficiency of nucleic acid amplification reactions with 3' modified oligonucleotides
US6379929B1 (en) 1996-11-20 2002-04-30 The Regents Of The University Of Michigan Chip-based isothermal amplification devices and methods
GB9626074D0 (en) 1996-12-16 1997-02-05 Cytocell Ltd Nucleic acids amplification assay
US6025133A (en) * 1996-12-30 2000-02-15 Gen-Probe Incorporated Promoter-sequestered oligonucleoside and method of use
US6534273B2 (en) 1997-05-02 2003-03-18 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
US6110678A (en) 1997-05-02 2000-08-29 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
DE69833864T2 (de) * 1997-08-14 2006-12-21 Takara Bio Inc., Otsu Methoden zur dns vervielfältigung und material dafür
AU1450699A (en) * 1997-10-31 1999-05-24 Gen-Probe Incorporated Methods of nucleic acid detection
US5932451A (en) * 1997-11-19 1999-08-03 Incyte Pharmaceuticals, Inc. Method for unbiased mRNA amplification
JP4438110B2 (ja) * 1998-07-01 2010-03-24 東ソー株式会社 標的核酸の定量方法
AU4739600A (en) * 1999-05-17 2000-12-05 Mcgill University Method for subtracting cdnas by suppressing the synthesis of specifically targeted mrnas
JP4796252B2 (ja) 1999-07-23 2011-10-19 ジェン−プローブ・インコーポレーテッド ポリヌクレオチド増幅方法
US6902891B2 (en) 1999-12-17 2005-06-07 Bio Merieux Process for labeling a nucleic acid
US6489114B2 (en) 1999-12-17 2002-12-03 Bio Merieux Process for labeling a ribonucleic acid, and labeled RNA fragments which are obtained thereby
JP2002051778A (ja) * 2000-05-31 2002-02-19 Tosoh Corp 小型球形ウイルス（ｓｒｓｖ）ｒｎａ検出のためのオリゴヌクレオチドおよび検出法
AUPR050700A0 (en) 2000-10-03 2000-10-26 Id+Plus Ltd Detection method
AU2001291513B2 (en) * 2000-10-03 2007-06-07 Id+Plus Ltd Nucleotide detection method
AU2002230545B2 (en) 2000-10-23 2006-09-21 Gen-Probe Incorporated Compositions and methods for detecting human immunodeficiency virus 2 (HIV-2)
JP2002125688A (ja) * 2000-10-30 2002-05-08 Tosoh Corp Ｃ型肝炎ウイルスの高感度検出のためのオリゴヌクレオチドおよび検出法
DE10119203B4 (de) * 2001-04-19 2004-09-16 Rolf Dr. Postina Verfahren zur Erzeugung von doppelsträngigen Nukleinsäuren mit einzelsträngigen Überhängen beliebiger Länge und Nukleotidzusammensetzung
ES2370169T3 (es) 2002-06-14 2011-12-13 Gen-Probe Incorporated Composiciones y métodos para detectar el virus de la hepatitis b.
WO2004036190A2 (en) 2002-10-16 2004-04-29 Gen-Probe Incorporated Compositions and methods for detecting west nile virus
WO2005061738A1 (en) 2003-12-19 2005-07-07 Gen-Probe Incorporated Compositions, methods and kits for detecting the nucleic acids of hiv-1 and hiv-2
DK2975139T3 (da) 2004-09-30 2019-12-09 Gen Probe Inc Assay til at detektere og kvantificere hiv-1
US20060223080A1 (en) 2004-11-09 2006-10-05 Gen-Probe Incorporated Compositions and methods for detecting group a streptococci
US7510837B2 (en) 2005-02-18 2009-03-31 Gen-Probe Incorporated Sample preparation method incorporating an alkaline shock
EP1877418B1 (de) 2005-05-06 2013-11-20 Gen-Probe Incorporated Zusammensetzungen und testanordnungen zur erkennung von nukleinsäuren des influenza-virus a
EP1955241B1 (de) 2005-11-14 2011-03-30 Gen-Probe Incorporated Parametrisches kalibrationsverfahren
CA2809734A1 (en) * 2006-05-24 2007-12-06 Gen-Probe Incorporated Compositions, methods and kits for determining the presence of mycobacterium tuberculosis complex organisms in a test sample
EP1921156A1 (de) * 2006-11-10 2008-05-14 bioMerieux B.V. Verbesserte multiplexe Nukleinsäureamplifikation mittels blockierter Primer
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
EP1978111B1 (de) * 2007-04-02 2013-03-27 Gen-Probe Incorporated Zusammensetzungen, Kits und zugehörige Verfahren zur Erkennung und/oder Überwachung von Pseudomonas aeruginosa
CA3128538C (en) 2008-04-21 2023-08-08 Gen-Probe Incorporated Method for detecting chikungunya virus
EP3118208A1 (de) 2009-02-26 2017-01-18 Gen-Probe Incorporated Assay zum nachweisen menschlicher parvovirennukleinsäure
US9234249B2 (en) 2010-07-12 2016-01-12 Gen-Probe Incorporated Compositions and assays to detect swine H1N1 influenza A virus, seasonal H1 influenza A virus and seasonal H3 influenza A virus nucleic acids
WO2012030856A2 (en) 2010-08-30 2012-03-08 Gen-Probe Incorporated Compositions, methods and reaction mixtures for the detection of xenotropic murine leukemia virus-related virus
EP3536809A1 (de) 2011-07-15 2019-09-11 Gen-Probe Incorporated Zusammensetzungen und verfahren zur detektion von humaner parvovirus-nukleinsäure
US9932628B2 (en) 2012-07-27 2018-04-03 Gen-Probe Incorporated Dual reference calibration method and system for quantifying polynucleotides
CN105264090B (zh) 2013-03-15 2020-04-07 简·探针公司 校准方法、设备和计算机程序产品
WO2018175868A1 (en) 2017-03-24 2018-09-27 Gen-Probe Incorporated Compositions and methods for detection of viral pathogens in samples
CA3241796A1 (en) 2017-03-24 2018-09-27 Gen-Probe Incorporated Compositions and methods for detecting or quantifying parainfluenza virus
EP3665309B1 (de) 2017-08-11 2023-02-22 Gen-Probe Incorporated Zusammensetzungen und verfahren zum nachweis von staphylococcus aureus
US20200318171A1 (en) 2017-12-15 2020-10-08 Gen-Probe Incorporated Compositions and Methods for Detecting Toxigenic Clostridium Difficile
GB2597569B (en) 2018-06-13 2023-01-25 Gen Probe Inc Compositions and methods for detecting group B streptococcus nucleic acid
AU2019314449A1 (en) 2018-08-01 2021-03-11 Gen-Probe Incorporated Compositions and methods for detecting nucleic acids of Epstein-Barr virus
CA3108105A1 (en) 2018-08-08 2020-02-13 Gen-Probe Incorporated Compositions, methods and kits for detecting mycoplasma genitalium
CA3107043A1 (en) 2018-08-21 2020-02-27 Gen-Probe Incorporated Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus
WO2020069085A2 (en) 2018-09-27 2020-04-02 Gen-Probe Incorporated Compositions and methods for detecting bordetella pertussis and bordetella parapertussis nucleic acid
EP3870722A1 (de) 2018-10-22 2021-09-01 Gen-Probe Incorporated Zusammensetzungen und verfahren zur amplifikation, detektion oder quantifizierung des menschlichen polyomavirus-bk-virus
WO2021041056A1 (en) 2019-08-23 2021-03-04 Gen-Probe Incorporated Compositions, methods and kits for detecting treponema pallidum
EP4025715A1 (de) 2019-09-05 2022-07-13 Gen-Probe Incorporated Nachweis von chlamydia-trachomatis-nukleinsäurevarianten
JP2023503946A (ja) 2019-12-09 2023-02-01 ジェン－プローブ・インコーポレーテッド 乾燥試料からのポリヌクレオチド分析物の定量化
US20230117369A1 (en) 2020-03-04 2023-04-20 Gen-Probe Incorporated Compositions and methods for detecting sars-cov-2 nucleaic acid
EP4382621A3 (de) 2021-07-27 2024-08-21 Gen-Probe Incorporated Zusammensetzungen und verfahren zum nachweis von c. coli und mindestens einer von salmonella, c. jejuni, shigella und stec
KR102544380B1 (ko) 2022-01-29 2023-06-16 (주)동방지퍼 지퍼용 슬라이더와 손잡이의 결착방법 및 이로 인해 제조된 지퍼
EP4282980A1 (de) 2022-05-23 2023-11-29 Mobidiag Oy Methoden zum verstärken einer nukleinsäure
WO2024054924A1 (en) 2022-09-08 2024-03-14 Gen-Probe Incorporated Method of detecting nucleic acid analytes using dual-specificity primers

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988003957A1 (en) * 1986-11-24 1988-06-02 Gen-Probe Incorporated Nucleic acid probes for detection and/or quantitation of non-viral organisms
IL86724A (en) * 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
US4994368A (en) * 1987-07-23 1991-02-19 Syntex (U.S.A.) Inc. Amplification method for polynucleotide assays
DE69034177T2 (de) * 1989-07-11 2005-10-27 Gen-Probe Inc., San Diego Verfahren zur Amplifikation von Nukleinsäuresequenzen
KR950013953B1 (ko) * 1990-01-26 1995-11-18 애보트 래보라토리즈 리가제 연쇄 반응에 적용가능한 표적 핵산의 증폭 방법
AU8920191A (en) * 1990-10-31 1992-05-26 George D. Cimino Methods and compositions for minimizing inhibition of nucleic acid amplification
US5169766A (en) * 1991-06-14 1992-12-08 Life Technologies, Inc. Amplification of nucleic acid molecules
US5521300A (en) * 1991-08-13 1996-05-28 Norval B. Galloway Oligonucleotides complementary to mycobacterial nucleic acids
AU681082B2 (en) * 1992-05-06 1997-08-21 Gen-Probe Incorporated Nucleic acid sequence amplification method, composition and kit

Also Published As

Publication number Publication date
EP0978570A3 (de) 2000-04-12
JP4372837B2 (ja) 2009-11-25
NO950381L (no) 1995-04-03
AU4792093A (en) 1994-03-03
JP3860809B2 (ja) 2006-12-20
AU6802796A (en) 1996-12-19
DE69334092D1 (de) 2007-01-11
EP0587298A2 (de) 1994-03-16
AU700253B2 (en) 1998-12-24
JP2004194662A (ja) 2004-07-15
ATE197479T1 (de) 2000-11-11
DE69334092T2 (de) 2007-07-05
JP2006238892A (ja) 2006-09-14
EP0587298A3 (en) 1995-08-30
EP0587298B1 (de) 2000-11-08
KR100316498B1 (ko) 2002-06-20
DE69329636T2 (de) 2001-03-01
DE69329636D1 (de) 2000-12-14
CA2141430A1 (en) 1994-02-17
EP0978570A2 (de) 2000-02-09
AU670116B2 (en) 1996-07-04
EP0978570B1 (de) 2006-11-29
ES2277679T3 (es) 2007-07-16
KR950702999A (ko) 1995-08-23
TW278099B (de) 1996-06-11
NO950381D0 (no) 1995-02-02
WO1994003472A1 (en) 1994-02-17
JPH07509368A (ja) 1995-10-19
CA2141430C (en) 2009-05-12

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