JP4268036B2 - 移植前の臓器の貯蔵および灌流用溶液 - Google Patents

移植前の臓器の貯蔵および灌流用溶液 Download PDF

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Publication number
JP4268036B2
JP4268036B2 JP2003504747A JP2003504747A JP4268036B2 JP 4268036 B2 JP4268036 B2 JP 4268036B2 JP 2003504747 A JP2003504747 A JP 2003504747A JP 2003504747 A JP2003504747 A JP 2003504747A JP 4268036 B2 JP4268036 B2 JP 4268036B2
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Japan
Prior art keywords
carnitine
acid
solution according
solution
organ
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JP2003504747A
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Japanese (ja)
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JP2004529205A5 (enExample
JP2004529205A (ja
Inventor
アルドゥイーノ・アルドゥイーニ
トンマソ・アウレーリ
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Sigma Tau Industrie Farmaceutiche Riunite SpA
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Sigma Tau Industrie Farmaceutiche Riunite SpA
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2003504747A 2001-06-14 2002-06-13 移植前の臓器の貯蔵および灌流用溶液 Expired - Fee Related JP4268036B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001RM000337A ITRM20010337A1 (it) 2001-06-14 2001-06-14 Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.
PCT/IT2002/000391 WO2002102149A1 (en) 2001-06-14 2002-06-13 Solution for the storage and perfusion of organs awaiting transplantation

Publications (3)

Publication Number Publication Date
JP2004529205A JP2004529205A (ja) 2004-09-24
JP2004529205A5 JP2004529205A5 (enExample) 2006-01-05
JP4268036B2 true JP4268036B2 (ja) 2009-05-27

Family

ID=11455594

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003504747A Expired - Fee Related JP4268036B2 (ja) 2001-06-14 2002-06-13 移植前の臓器の貯蔵および灌流用溶液

Country Status (15)

Country Link
US (3) US7422844B2 (enExample)
EP (1) EP1401270B1 (enExample)
JP (1) JP4268036B2 (enExample)
KR (1) KR100844191B1 (enExample)
AT (1) ATE336166T1 (enExample)
CA (1) CA2450623C (enExample)
CY (1) CY1106202T1 (enExample)
DE (1) DE60213990T2 (enExample)
DK (1) DK1401270T3 (enExample)
ES (1) ES2271290T3 (enExample)
IT (1) ITRM20010337A1 (enExample)
MX (1) MXPA03011461A (enExample)
PL (1) PL206312B1 (enExample)
PT (1) PT1401270E (enExample)
WO (1) WO2002102149A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20010337A1 (it) * 2001-06-14 2002-12-16 Sigma Tau Ind Farmaceuti Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.
JP2005095152A (ja) * 2003-08-29 2005-04-14 Japan Tissue Engineering:Kk 培養組織の保存方法
WO2006026304A1 (en) * 2004-08-25 2006-03-09 Ivax Corporation Cardioprotective formulations and uses thereof
TWI388318B (zh) * 2005-03-10 2013-03-11 西格瑪 陶製藥廠 具有改良之生物相容性的含有肉毒鹼之腹膜透析溶液
JP2006347935A (ja) * 2005-06-15 2006-12-28 Masanori Ogata 炎症性サイトカインの産生が関与する疾患の予防及び／又は治療のための医薬
GB0612877D0 (en) * 2006-06-29 2006-08-09 Univ Edinburgh Organ preservation solution
EP2543249B1 (en) 2007-02-17 2018-05-23 President and Fellows of Harvard College Compositions and method for tissue preservation
CN102088968A (zh) 2008-02-15 2011-06-08 哈佛学院董事会 血液替代溶液
JP5201218B2 (ja) * 2009-06-15 2013-06-05 トヨタ自動車株式会社 無細胞タンパク質合成溶液、無細胞タンパク質合成キット及びタンパク質合成方法
RU2707532C1 (ru) * 2018-10-11 2019-11-27 Российская Федерация, от имени которой выступает ФОНД ПЕРСПЕКТИВНЫХ ИССЛЕДОВАНИЙ Способ повышения безопасности и эффективности хранения и транспортировки трансплантируемого органа под давлением консервирующей газовой смеси и устройство на его основе
CN109511650B (zh) * 2018-11-21 2021-06-15 嘉兴莱普晟医疗科技有限公司 一种可以扩大供肝来源的常温机械灌注液
IT201900007446A1 (it) * 2019-05-29 2020-11-29 Giuseppe Castellano Composizione comprendente citrato e carnitina in grado di attivare la produzione della proteina klotho
WO2021183653A1 (en) * 2020-03-10 2021-09-16 University Of Florida Research Foundation, Incorporated Compositions for extending viable preservation and shelf-life of organs and tissues

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498427A (en) 1990-11-20 1996-03-12 Pasteur Merieux Serums Et Vaccines Solutions for the perfusion, preservation and reperfusion of organs
IT1261695B (it) * 1993-06-02 1996-05-29 Sigma Tau Ind Farmaceuti Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono.
WO1996018293A1 (en) * 1994-12-12 1996-06-20 Charlotte-Mecklenburg Hospital Authority Organ transplant solutions and method for transplanting an organ
US5707971A (en) * 1995-06-07 1998-01-13 Life Resuscitation Technologies, Inc. Modulation of glycolytic ATP production
US5834178C1 (en) * 1997-07-09 2002-04-23 Univ Wayne State Flush-storage solution for donor organs
CA2352485A1 (en) * 1998-11-26 2000-06-02 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of fumarate salt of l-carnitine or its alkanoyl derivatives in ischaemia
HUP0203441A3 (en) 1999-10-11 2004-01-28 Sigma Tau Ind Farmaceuti Use of l-carnitine and its alkanoyl derivatives as osmotic agents and solutions for medical use
ITRM20010337A1 (it) 2001-06-14 2002-12-16 Sigma Tau Ind Farmaceuti Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.

Also Published As

Publication number Publication date
KR100844191B1 (ko) 2008-07-04
CY1106202T1 (el) 2011-06-08
ES2271290T3 (es) 2007-04-16
JP2004529205A (ja) 2004-09-24
WO2002102149A1 (en) 2002-12-27
CA2450623C (en) 2011-05-10
US8007993B2 (en) 2011-08-30
DE60213990D1 (de) 2006-09-28
ITRM20010337A1 (it) 2002-12-16
KR20040010712A (ko) 2004-01-31
EP1401270A1 (en) 2004-03-31
US20080199844A1 (en) 2008-08-21
US7989158B2 (en) 2011-08-02
DE60213990T2 (de) 2007-03-15
ATE336166T1 (de) 2006-09-15
DK1401270T3 (da) 2006-12-27
US20080166695A1 (en) 2008-07-10
US20040156990A1 (en) 2004-08-12
PL206312B1 (pl) 2010-07-30
CA2450623A1 (en) 2002-12-27
PL367837A1 (en) 2005-03-07
US7422844B2 (en) 2008-09-09
EP1401270B1 (en) 2006-08-16
MXPA03011461A (es) 2004-07-01
ITRM20010337A0 (it) 2001-06-14
PT1401270E (pt) 2006-10-31

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