JP4223814B2 - 四級アンモニウム化合物、シランおよび他の殺菌剤をフラノンとともに含有する抗菌性組成物 - Google Patents
四級アンモニウム化合物、シランおよび他の殺菌剤をフラノンとともに含有する抗菌性組成物 Download PDFInfo
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- JP4223814B2 JP4223814B2 JP2002578725A JP2002578725A JP4223814B2 JP 4223814 B2 JP4223814 B2 JP 4223814B2 JP 2002578725 A JP2002578725 A JP 2002578725A JP 2002578725 A JP2002578725 A JP 2002578725A JP 4223814 B2 JP4223814 B2 JP 4223814B2
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- Prior art keywords
- furanone
- quaternary ammonium
- composition
- formulation
- ammonium compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
- A01N43/08—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with oxygen as the ring hetero atom
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- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Detergent Compositions (AREA)
- Cleaning In General (AREA)
- Cleaning By Liquid Or Steam (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Description
本出願は、米国仮出願第60/249,253号(2000年11月17日出願)の利益を主張をする。
A3-xBxSiD
式中、
Aは−OH基または加水分解性の基であり、
Bは、炭素原子が1個から4個のアルキル基であり、
Xは0または1または2の値を有し、かつ
Dは、(i)炭素原子が1個から4個の炭化水素基、(ii)フェニル基、または(iii)少なくとも1つの窒素基を含有する非イオン性もしくはカチオン性の置換炭化水素基またはそのような置換炭化水素基の塩である。
使用菌類:Alternaria alternata、Aureobasidium pullulans、Cladosporium cladosporioides、Penicillium digitatum
方法:A、B、CおよびDに対する基本配合物を、下記の表1に記載されるように調製した。
・減少する濃度での混合物としてのフラノン26およびフラノン27(表2Aから表2Dでは、「26/27」として示される)、
・フラノンの添加がない配合物A単独(表2Aから表2Dでは、「A」として示される)、
・フラノンの添加がない配合物B単独(表2Aから表2Dでは、「B」として示される)、
・配合物Aまたは配合物Bを伴う、減少する濃度でのフラノン30(表2Aから表2Dでは、「30+A」または「30+B」として示される)、および
・配合物Aまたは配合物Bを伴う、減少する濃度での混合物としてのフラノン26およびフラノン27(表2Aから表2Dでは、「26/27+A」または「26/27+B」として示される)。
目的:四級化有機シラン単独もしくはフラノン単独の組成物、または四級アンモニウム化合物と組み合わせた四級化有機シランの組成物を比較対象として、フラノンと、四級化有機シランと、四級アンモニウム化合物とを含む本発明の組成物のStaphylococcus aureusに対する有効性を明らかにすること。
1.フラノン単独および四級化有機シラン単独(配合物Gおよび配合物E)は、非常に低い濃度では細菌の増殖を抑制することができなかった。(ガラス製スライドガラスに吸着された量は不明である)。
使用生物:Staphylococcus aureus
方法:滅菌されたろ紙を寒天平板(TSA)の上に置き、Staphylococus aureusの希釈された(10%)オーバーナイトカルチャーの1mlを接種した。ガラス製スライドガラス(1インチ×2インチ)の一方の側を、(実施例2に示される)表3における配合に従って調製された配合物E、F、GまたはHで湿らせた。
使用生物:Aspergillus niger
方法:試験配合物を、上記の表3に示されるように調製した。
2日目:
・配合物Eおよび配合物Gは効果を示さなかった。Aspergillus nigerの胞子が発芽し、増殖により、TLCプレートの試験表面を含む表面全体が覆われた。
・配合物Eおよび配合物Gは完全に過増殖し、処理の効果は全く認められなかった。
Claims (2)
- (a)フラノン30又は混合物としてのフラノン26およびフラノン27から選ばれる少量の少なくとも1つのフラノンと、
(b)少量の塩化3−(トリメトキシシリル)プロピルジメチルオクタデシルアンモニウムと、
(c)塩化ベンザルコニウムおよび塩化エチルベンザルコニウムの混合物又は塩化ジデシルジメチルアンモニウムから選ばれる少量の少なくとも1つの四級アンモニウム化合物と、
を含み、成分(a)、成分(b)および成分(c)の量はそれぞれ、組み合わせにより相乗的な抗菌性組成物を形成するために十分である、組成物。 - 表面、または液体で満たされる容器もしくは導管を清浄化する方法であって、
(a)フラノン30又は混合物としてのフラノン26およびフラノン27から選ばれる少量の少なくとも1つのフラノンと、
(b)少量の塩化3−(トリメトキシシリル)プロピルジメチルオクタデシルアンモニウムと、
(c)塩化ベンザルコニウムおよび塩化エチルベンザルコニウムの混合物又は塩化ジデシルジメチルアンモニウムから選ばれる少量の少なくとも1つの四級アンモニウム化合物と、
を含む相乗的な抗菌性組成物を、清浄化される表面または容器または導管に適用することを含む方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24925300P | 2000-11-17 | 2000-11-17 | |
US09/986,301 US6528472B2 (en) | 2000-11-17 | 2001-11-08 | Antimicrobial compositions containing quaternary ammonium compounds, silanes and other disinfectants with furanones |
PCT/US2001/043886 WO2002080677A1 (en) | 2000-11-17 | 2001-11-16 | Antimicrobial compositions containing quaternary ammonium compounds, silanes and other disinfectants with furanones |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2004524367A JP2004524367A (ja) | 2004-08-12 |
JP2004524367A5 JP2004524367A5 (ja) | 2005-12-22 |
JP4223814B2 true JP4223814B2 (ja) | 2009-02-12 |
Family
ID=26939928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2002578725A Expired - Fee Related JP4223814B2 (ja) | 2000-11-17 | 2001-11-16 | 四級アンモニウム化合物、シランおよび他の殺菌剤をフラノンとともに含有する抗菌性組成物 |
Country Status (11)
Country | Link |
---|---|
US (1) | US6528472B2 (ja) |
EP (1) | EP1349454B1 (ja) |
JP (1) | JP4223814B2 (ja) |
AR (1) | AR031478A1 (ja) |
AT (1) | ATE308243T1 (ja) |
CA (1) | CA2428789A1 (ja) |
DE (1) | DE60114665T2 (ja) |
ES (1) | ES2247011T3 (ja) |
MX (1) | MXPA03004359A (ja) |
TW (1) | TWI244394B (ja) |
WO (1) | WO2002080677A1 (ja) |
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-
2001
- 2001-11-08 US US09/986,301 patent/US6528472B2/en not_active Expired - Lifetime
- 2001-11-16 JP JP2002578725A patent/JP4223814B2/ja not_active Expired - Fee Related
- 2001-11-16 ES ES01273631T patent/ES2247011T3/es not_active Expired - Lifetime
- 2001-11-16 WO PCT/US2001/043886 patent/WO2002080677A1/en active IP Right Grant
- 2001-11-16 DE DE60114665T patent/DE60114665T2/de not_active Expired - Fee Related
- 2001-11-16 CA CA002428789A patent/CA2428789A1/en not_active Abandoned
- 2001-11-16 MX MXPA03004359A patent/MXPA03004359A/es unknown
- 2001-11-16 AT AT01273631T patent/ATE308243T1/de not_active IP Right Cessation
- 2001-11-16 EP EP01273631A patent/EP1349454B1/en not_active Expired - Lifetime
- 2001-11-19 TW TW090128625A patent/TWI244394B/zh not_active IP Right Cessation
- 2001-11-19 AR ARP010105393A patent/AR031478A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
ATE308243T1 (de) | 2005-11-15 |
US20020111282A1 (en) | 2002-08-15 |
EP1349454A1 (en) | 2003-10-08 |
JP2004524367A (ja) | 2004-08-12 |
DE60114665D1 (de) | 2005-12-08 |
CA2428789A1 (en) | 2002-10-17 |
US6528472B2 (en) | 2003-03-04 |
DE60114665T2 (de) | 2006-07-20 |
TWI244394B (en) | 2005-12-01 |
WO2002080677A1 (en) | 2002-10-17 |
MXPA03004359A (es) | 2005-04-19 |
AR031478A1 (es) | 2003-09-24 |
ES2247011T3 (es) | 2006-03-01 |
EP1349454B1 (en) | 2005-11-02 |
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