JP4189048B2 - 複素環化合物 - Google Patents
複素環化合物 Download PDFInfo
- Publication number
- JP4189048B2 JP4189048B2 JP36788797A JP36788797A JP4189048B2 JP 4189048 B2 JP4189048 B2 JP 4189048B2 JP 36788797 A JP36788797 A JP 36788797A JP 36788797 A JP36788797 A JP 36788797A JP 4189048 B2 JP4189048 B2 JP 4189048B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- carbon atoms
- substituted
- alkyl
- same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 **c(nc1[n]2Cc3ccccc3)nc(N)c1nc2O Chemical compound **c(nc1[n]2Cc3ccccc3)nc(N)c1nc2O 0.000 description 3
- BQGDDAYSNFLDLH-UHFFFAOYSA-N CC(C)CSc1nc(N)c2nc[n](Cc3ccccc3)c2n1 Chemical compound CC(C)CSc1nc(N)c2nc[n](Cc3ccccc3)c2n1 BQGDDAYSNFLDLH-UHFFFAOYSA-N 0.000 description 1
- CTFPXLSBZGGGJG-UHFFFAOYSA-N CCCSc(nc1[n]2Cc3ccccc3)nc(N)c1nc2Br Chemical compound CCCSc(nc1[n]2Cc3ccccc3)nc(N)c1nc2Br CTFPXLSBZGGGJG-UHFFFAOYSA-N 0.000 description 1
- VGSBMDOWAWHTIU-UHFFFAOYSA-N CCSc(nc1N)nc([n]2Cc3ccccc3)c1nc2O Chemical compound CCSc(nc1N)nc([n]2Cc3ccccc3)c1nc2O VGSBMDOWAWHTIU-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP36788797A JP4189048B2 (ja) | 1997-12-26 | 1997-12-26 | 複素環化合物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP36788797A JP4189048B2 (ja) | 1997-12-26 | 1997-12-26 | 複素環化合物 |
Publications (3)
Publication Number | Publication Date |
---|---|
JPH11193282A JPH11193282A (ja) | 1999-07-21 |
JPH11193282A5 JPH11193282A5 (enrdf_load_html_response) | 2005-09-02 |
JP4189048B2 true JP4189048B2 (ja) | 2008-12-03 |
Family
ID=18490454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP36788797A Expired - Fee Related JP4189048B2 (ja) | 1997-12-26 | 1997-12-26 | 複素環化合物 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP4189048B2 (enrdf_load_html_response) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1386923B1 (en) | 2001-04-17 | 2008-08-13 | Dainippon Sumitomo Pharma Co., Ltd. | Novel adenine derivatives |
NZ539064A (en) | 2002-09-27 | 2007-09-28 | Dainippon Sumitomo Pharma Co | Novel adenine compound and use thereof |
ATE465742T1 (de) * | 2003-09-05 | 2010-05-15 | Anadys Pharmaceuticals Inc | Tlr7-liganden zur behandlung von hepatitis c |
US8012964B2 (en) | 2004-03-26 | 2011-09-06 | Dainippon Sumitomo Pharma Co., Ltd. | 9-substituted 8-oxoadenine compound |
CA2620182A1 (en) | 2005-08-22 | 2007-03-01 | Dennis A. Carson | Tlr agonists |
AU2007216247A1 (en) | 2006-02-17 | 2007-08-23 | Pfizer Limited | 3 -deazapurine derivatives as TLR7 modulators |
EP2041135A4 (en) | 2006-07-05 | 2010-12-01 | Astrazeneca Ab | As TLR7 MODULATORS, 8-OXOADENINE DERIVATIVES WORK |
TW200831105A (en) | 2006-12-14 | 2008-08-01 | Astrazeneca Ab | Novel compounds |
CA2677733A1 (en) | 2007-02-07 | 2008-09-25 | The Regents Of The University Of California | Conjugates of synthetic tlr agonists and uses therefor |
SI2132209T1 (sl) | 2007-03-19 | 2014-05-30 | Astrazeneca Ab | Spojine 9-substituiranega-8-okso-adenina, kot modulatorji Toll-like receptorja (TLR7) |
US8063051B2 (en) | 2007-03-19 | 2011-11-22 | Astrazeneca Ab | 9-substituted-8-oxo-adenine compounds as toll-like receptor (TLR7) modulators |
TW200902018A (en) * | 2007-03-20 | 2009-01-16 | Dainippon Sumitomo Pharma Co | Novel adenine compound |
EP2138497A4 (en) | 2007-03-20 | 2012-01-04 | Dainippon Sumitomo Pharma Co | NEW ADENINE CONNECTION |
BRPI0811125A2 (pt) | 2007-05-08 | 2017-05-09 | Astrazeneca Ab | imidazoquinolinas com propriedades imunomoduladoras |
PE20091236A1 (es) | 2007-11-22 | 2009-09-16 | Astrazeneca Ab | Derivados de pirimidina como immunomoduladores de tlr7 |
PE20091156A1 (es) | 2007-12-17 | 2009-09-03 | Astrazeneca Ab | Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo |
WO2009091032A1 (ja) | 2008-01-17 | 2009-07-23 | Dainippon Sumitomo Pharma Co., Ltd. | アデニン化合物の製造方法 |
WO2010088924A1 (en) | 2009-02-06 | 2010-08-12 | Telormedix Sa | Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration |
AU2010250923A1 (en) | 2009-05-21 | 2011-11-17 | Astrazeneca Ab | Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases |
GB0908772D0 (en) | 2009-05-21 | 2009-07-01 | Astrazeneca Ab | New salts 756 |
PT2491035T (pt) | 2009-10-22 | 2017-10-30 | Gilead Sciences Inc | Derivados de purina ou deazapurina úteis para o tratamento de (entre outros) infeções virais |
US9050319B2 (en) | 2010-04-30 | 2015-06-09 | Telormedix, Sa | Phospholipid drug analogs |
WO2011134668A1 (en) | 2010-04-30 | 2011-11-03 | Telormedix Sa | Phospholipid drug analogs |
CN103370317B (zh) | 2010-12-16 | 2015-10-07 | 阿斯利康(瑞典)有限公司 | 可用于治疗的咪唑并[4,5-c]喹啉-1-基衍生物 |
JP5978226B2 (ja) | 2010-12-17 | 2016-08-24 | 大日本住友製薬株式会社 | プリン誘導体 |
CN104302628B (zh) | 2012-05-18 | 2017-06-23 | 大日本住友制药株式会社 | 羧酸化合物 |
SI3294740T1 (sl) * | 2015-05-08 | 2019-12-31 | F. Hoffmann-La Roche Ag | Nove sulfonimidoilpurinonske spojine in derivati za zdravljenje virusne okužbe in zaščito pred njo |
US11697851B2 (en) | 2016-05-24 | 2023-07-11 | The Regents Of The University Of California | Early ovarian cancer detection diagnostic test based on mRNA isoforms |
RU2751349C2 (ru) * | 2016-08-29 | 2021-07-13 | Ф. Хоффманн-Ля Рош Аг | 7-замещенные сульфонимидоилпуриноны для лечения и профилактики вирусной инфекции |
KR102497701B1 (ko) | 2016-09-13 | 2023-02-09 | 에프. 호프만-라 로슈 아게 | Tlr7 작용제 및 hbv 캡시드 조립 억제제의 병용 치료 |
EP3752505B1 (en) | 2018-02-12 | 2023-01-11 | F. Hoffmann-La Roche AG | Novel sulfone compounds and derivatives for the treatment and prophylaxis of virus infection |
RU2020131012A (ru) | 2018-02-28 | 2022-03-28 | Ф. Хоффманн-Ля Рош Аг | 7-замещенные соединения сульфонимидоилпуринонов и их производные для лечения и профилактики рака печени |
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1997
- 1997-12-26 JP JP36788797A patent/JP4189048B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH11193282A (ja) | 1999-07-21 |
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