JP4183943B2 - 15−ケトプロスタグランジンを含む胆汁分泌促進剤組成物 - Google Patents

15−ケトプロスタグランジンを含む胆汁分泌促進剤組成物 Download PDF

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Publication number
JP4183943B2
JP4183943B2 JP2001574111A JP2001574111A JP4183943B2 JP 4183943 B2 JP4183943 B2 JP 4183943B2 JP 2001574111 A JP2001574111 A JP 2001574111A JP 2001574111 A JP2001574111 A JP 2001574111A JP 4183943 B2 JP4183943 B2 JP 4183943B2
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Prior art keywords
keto
group
composition
compound
prostaglandin
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JP2001574111A
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Japanese (ja)
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JP2004519412A5 (enExample
JP2004519412A (ja
Inventor
隆司 上野
誠 末松
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Sucampo GmbH
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Sucampo GmbH
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2001574111A 2000-04-06 2001-04-05 15−ケトプロスタグランジンを含む胆汁分泌促進剤組成物 Expired - Fee Related JP4183943B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19489400P 2000-04-06 2000-04-06
PCT/JP2001/002938 WO2001076593A2 (en) 2000-04-06 2001-04-05 Bile secretion promoting composition a 15-keto prostaglandin

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008148107A Division JP5073588B2 (ja) 2000-04-06 2008-06-05 15−ケトプロスタグランジンを含む胆汁分泌促進剤組成物

Publications (3)

Publication Number Publication Date
JP2004519412A JP2004519412A (ja) 2004-07-02
JP2004519412A5 JP2004519412A5 (enExample) 2005-06-30
JP4183943B2 true JP4183943B2 (ja) 2008-11-19

Family

ID=22719290

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2001574111A Expired - Fee Related JP4183943B2 (ja) 2000-04-06 2001-04-05 15−ケトプロスタグランジンを含む胆汁分泌促進剤組成物
JP2008148107A Expired - Fee Related JP5073588B2 (ja) 2000-04-06 2008-06-05 15−ケトプロスタグランジンを含む胆汁分泌促進剤組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008148107A Expired - Fee Related JP5073588B2 (ja) 2000-04-06 2008-06-05 15−ケトプロスタグランジンを含む胆汁分泌促進剤組成物

Country Status (15)

Country Link
US (2) US6469062B2 (enExample)
EP (1) EP1267883B1 (enExample)
JP (2) JP4183943B2 (enExample)
KR (1) KR100874626B1 (enExample)
CN (1) CN1241570C (enExample)
AR (1) AR030277A1 (enExample)
AT (1) ATE433754T1 (enExample)
AU (2) AU4472701A (enExample)
BR (1) BR0107544A (enExample)
CA (1) CA2404767C (enExample)
DE (1) DE60139002D1 (enExample)
MX (1) MXPA02009915A (enExample)
NZ (1) NZ521784A (enExample)
TW (1) TWI232750B (enExample)
WO (1) WO2001076593A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4183943B2 (ja) * 2000-04-06 2008-11-19 スキャンポ・アーゲー 15−ケトプロスタグランジンを含む胆汁分泌促進剤組成物
EP1420794B1 (en) 2001-08-31 2017-12-27 Sucampo AG Prostaglandin analogs as chloride channel openers
AR037524A1 (es) 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
US7732487B2 (en) 2001-11-19 2010-06-08 Sucampo Ag Method for treating a disease or condition responsive to opening of C1C-2 channel
MXPA05006981A (es) * 2002-12-27 2005-12-14 Sucampo Ag Derivados de prostaglandinas para el tratamiento de la molestia abdominal.
CA2602812C (en) * 2005-04-12 2014-11-18 Sucampo Ag Combined use of prostaglandin compound and proton pump inhibitor for the treatment of gastrointestinal disorders
US8815557B2 (en) * 2005-07-08 2014-08-26 University Of Chicago Compositions and methods for refolding of denatured proteins
AU2007223469B2 (en) * 2006-02-28 2012-06-07 Sucampo Ag Method and composition for treating chronic obstructive pulmonary disease
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
US11534404B2 (en) 2016-10-06 2022-12-27 Sucampo Ag Multilayer beads for pharmaceutical use
KR102595299B1 (ko) 2020-10-12 2023-10-26 류형준 담즙 분비 촉진 효능이 있는 식품 조성물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58203911A (ja) * 1982-05-25 1983-11-28 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤
JPS6327433A (ja) 1986-07-21 1988-02-05 Teijin Ltd 肝疾患治療剤
US5166174A (en) 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
CA1322749C (en) 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
US5221763A (en) 1987-04-30 1993-06-22 R-Tech Ueno, Ltd. Prostaglandins of the F series
US5076569A (en) * 1989-09-15 1991-12-31 Gootter Steven M Contoured grip for exercising the hand
CA2027814C (en) * 1989-10-20 1996-07-30 Ryuji Ueno Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
TW249226B (enExample) 1990-04-04 1995-06-11 Aderk Ueno Kk
EP0455448B1 (en) * 1990-05-01 1998-12-09 R-Tech Ueno Ltd. Treatment of pancreatic disease with 15-keto-prostaglandin E compounds
JPH069404A (ja) 1992-06-23 1994-01-18 Ono Pharmaceut Co Ltd 臓器移植用薬剤
CA2150287C (en) * 1994-06-03 2004-08-10 Ryuji Ueno Agent for treating hepato-biliary diseases
JP3183615B2 (ja) * 1994-06-03 2001-07-09 株式会社アールテック・ウエノ 肝・胆道系疾患処置剤
JP4183943B2 (ja) * 2000-04-06 2008-11-19 スキャンポ・アーゲー 15−ケトプロスタグランジンを含む胆汁分泌促進剤組成物

Also Published As

Publication number Publication date
EP1267883A2 (en) 2003-01-02
CA2404767A1 (en) 2001-10-18
EP1267883B1 (en) 2009-06-17
KR20020087123A (ko) 2002-11-21
BR0107544A (pt) 2005-01-11
MXPA02009915A (es) 2003-03-27
US20030060506A1 (en) 2003-03-27
CA2404767C (en) 2010-12-07
US20020004524A1 (en) 2002-01-10
WO2001076593A3 (en) 2002-07-11
JP2004519412A (ja) 2004-07-02
DE60139002D1 (de) 2009-07-30
US6469062B2 (en) 2002-10-22
KR100874626B1 (ko) 2008-12-17
AU2001244727B2 (en) 2006-08-10
ATE433754T1 (de) 2009-07-15
AU4472701A (en) 2001-10-23
JP5073588B2 (ja) 2012-11-14
CN1241570C (zh) 2006-02-15
JP2008291033A (ja) 2008-12-04
CN1450899A (zh) 2003-10-22
NZ521784A (en) 2005-04-29
WO2001076593A2 (en) 2001-10-18
AR030277A1 (es) 2003-08-20
TWI232750B (en) 2005-05-21

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