AU2001244727B2 - Bile secretion promoting composition - Google Patents

Bile secretion promoting composition Download PDF

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Publication number
AU2001244727B2
AU2001244727B2 AU2001244727A AU2001244727A AU2001244727B2 AU 2001244727 B2 AU2001244727 B2 AU 2001244727B2 AU 2001244727 A AU2001244727 A AU 2001244727A AU 2001244727 A AU2001244727 A AU 2001244727A AU 2001244727 B2 AU2001244727 B2 AU 2001244727B2
Authority
AU
Australia
Prior art keywords
keto
compound
prostaglandin
alkyl
prostaglandin compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2001244727A
Other languages
English (en)
Other versions
AU2001244727A2 (en
AU2001244727A1 (en
Inventor
Makoto Suematsu
Ryuji Ueno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucampo GmbH
Original Assignee
Sucampo GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sucampo GmbH filed Critical Sucampo GmbH
Publication of AU2001244727A1 publication Critical patent/AU2001244727A1/en
Publication of AU2001244727A2 publication Critical patent/AU2001244727A2/en
Application granted granted Critical
Publication of AU2001244727B2 publication Critical patent/AU2001244727B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2001244727A 2000-04-06 2001-04-05 Bile secretion promoting composition Ceased AU2001244727B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19489400P 2000-04-06 2000-04-06
US60/194,894 2000-04-06
PCT/JP2001/002938 WO2001076593A2 (en) 2000-04-06 2001-04-05 Bile secretion promoting composition a 15-keto prostaglandin

Publications (3)

Publication Number Publication Date
AU2001244727A1 AU2001244727A1 (en) 2002-01-10
AU2001244727A2 AU2001244727A2 (en) 2003-06-05
AU2001244727B2 true AU2001244727B2 (en) 2006-08-10

Family

ID=22719290

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001244727A Ceased AU2001244727B2 (en) 2000-04-06 2001-04-05 Bile secretion promoting composition
AU4472701A Pending AU4472701A (en) 2000-04-06 2001-04-05 Bile secretion promoting composition

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU4472701A Pending AU4472701A (en) 2000-04-06 2001-04-05 Bile secretion promoting composition

Country Status (15)

Country Link
US (2) US6469062B2 (enExample)
EP (1) EP1267883B1 (enExample)
JP (2) JP4183943B2 (enExample)
KR (1) KR100874626B1 (enExample)
CN (1) CN1241570C (enExample)
AR (1) AR030277A1 (enExample)
AT (1) ATE433754T1 (enExample)
AU (2) AU2001244727B2 (enExample)
BR (1) BR0107544A (enExample)
CA (1) CA2404767C (enExample)
DE (1) DE60139002D1 (enExample)
MX (1) MXPA02009915A (enExample)
NZ (1) NZ521784A (enExample)
TW (1) TWI232750B (enExample)
WO (1) WO2001076593A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE433754T1 (de) * 2000-04-06 2009-07-15 Sucampo Ag Gallensäurefördernde zusammensetzung für lebertransplantation welche ein 15-keto prostaglandin enthält
JP4786866B2 (ja) 2001-08-31 2011-10-05 スキャンポ・アーゲー クロライドチャンネルオープナーとしてのプロスタグランジンアナログ
AR037524A1 (es) 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
US7732487B2 (en) * 2001-11-19 2010-06-08 Sucampo Ag Method for treating a disease or condition responsive to opening of C1C-2 channel
JP4889219B2 (ja) 2002-12-27 2012-03-07 スキャンポ・アーゲー 腹部不快感の処置のためのプロスタグランジン誘導体
KR101466980B1 (ko) * 2005-04-12 2014-12-01 수캄포 아게 위장 장애 치료를 위한 프로스타글란딘 화합물과 양성자펌프 억제제의 병용
WO2007008697A2 (en) * 2005-07-08 2007-01-18 University Of Chicago Compositions and methods for refolding of denatured proteins
JP5377970B2 (ja) * 2006-02-28 2013-12-25 スキャンポ・アーゲー 慢性閉塞性肺疾患を処置するための方法および組成物
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
US11534404B2 (en) 2016-10-06 2022-12-27 Sucampo Ag Multilayer beads for pharmaceutical use
KR102595299B1 (ko) 2020-10-12 2023-10-26 류형준 담즙 분비 촉진 효능이 있는 식품 조성물

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096927A (en) * 1989-10-20 1992-03-17 K.K. Ueno Seiyaku Oyo Kenkyujo Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
EP0690049B1 (en) * 1994-06-03 1999-08-04 R-Tech Ueno Ltd. Agent for treating hepato biliary diseases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58203911A (ja) * 1982-05-25 1983-11-28 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤
JPS6327433A (ja) 1986-07-21 1988-02-05 Teijin Ltd 肝疾患治療剤
US5166174A (en) 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
CA1322749C (en) 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
US5221763A (en) 1987-04-30 1993-06-22 R-Tech Ueno, Ltd. Prostaglandins of the F series
US5076569A (en) * 1989-09-15 1991-12-31 Gootter Steven M Contoured grip for exercising the hand
TW249226B (enExample) 1990-04-04 1995-06-11 Aderk Ueno Kk
DE69130586T2 (de) * 1990-05-01 1999-06-17 R-Tech Ueno, Ltd., Osaka Behandlung von Pankreaskrankheit mit 15-keto-Prostaglandin E-Derivaten
JPH069404A (ja) 1992-06-23 1994-01-18 Ono Pharmaceut Co Ltd 臓器移植用薬剤
JP3183615B2 (ja) * 1994-06-03 2001-07-09 株式会社アールテック・ウエノ 肝・胆道系疾患処置剤
ATE433754T1 (de) * 2000-04-06 2009-07-15 Sucampo Ag Gallensäurefördernde zusammensetzung für lebertransplantation welche ein 15-keto prostaglandin enthält

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096927A (en) * 1989-10-20 1992-03-17 K.K. Ueno Seiyaku Oyo Kenkyujo Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
EP0424156B1 (en) * 1989-10-20 1996-01-10 R-Tech Ueno Ltd. Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
EP0690049B1 (en) * 1994-06-03 1999-08-04 R-Tech Ueno Ltd. Agent for treating hepato biliary diseases

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Beckh et al. Direct Regulation of Bile Secretion by Prostaglandins in Perfused Rat Liver (1994) Hepatology, vol 19(5), pg 1208-1213 *
Lou et al. Inhibition of Leukocyte Adherence and Transendothelial Migration in Cultured Human Liver Vascular Endothelial Cells by Prostaglandin E1 (1998) Hepatology, vol 27(3), pg 822-828 *

Also Published As

Publication number Publication date
TWI232750B (en) 2005-05-21
KR20020087123A (ko) 2002-11-21
US20030060506A1 (en) 2003-03-27
WO2001076593A2 (en) 2001-10-18
AR030277A1 (es) 2003-08-20
ATE433754T1 (de) 2009-07-15
KR100874626B1 (ko) 2008-12-17
CA2404767A1 (en) 2001-10-18
EP1267883B1 (en) 2009-06-17
CA2404767C (en) 2010-12-07
JP2004519412A (ja) 2004-07-02
JP4183943B2 (ja) 2008-11-19
US6469062B2 (en) 2002-10-22
CN1241570C (zh) 2006-02-15
JP2008291033A (ja) 2008-12-04
NZ521784A (en) 2005-04-29
WO2001076593A3 (en) 2002-07-11
BR0107544A (pt) 2005-01-11
JP5073588B2 (ja) 2012-11-14
EP1267883A2 (en) 2003-01-02
DE60139002D1 (de) 2009-07-30
AU4472701A (en) 2001-10-23
US20020004524A1 (en) 2002-01-10
CN1450899A (zh) 2003-10-22
MXPA02009915A (es) 2003-03-27

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 09 JAN 2003

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired