AU2001244727B2 - Bile secretion promoting composition - Google Patents

Bile secretion promoting composition Download PDF

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Publication number
AU2001244727B2
AU2001244727B2 AU2001244727A AU2001244727A AU2001244727B2 AU 2001244727 B2 AU2001244727 B2 AU 2001244727B2 AU 2001244727 A AU2001244727 A AU 2001244727A AU 2001244727 A AU2001244727 A AU 2001244727A AU 2001244727 B2 AU2001244727 B2 AU 2001244727B2
Authority
AU
Australia
Prior art keywords
keto
compound
prostaglandin
alkyl
prostaglandin compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2001244727A
Other languages
English (en)
Other versions
AU2001244727A2 (en
AU2001244727A1 (en
Inventor
Makoto Suematsu
Ryuji Ueno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucampo GmbH
Original Assignee
Sucampo GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sucampo GmbH filed Critical Sucampo GmbH
Publication of AU2001244727A1 publication Critical patent/AU2001244727A1/en
Publication of AU2001244727A2 publication Critical patent/AU2001244727A2/en
Application granted granted Critical
Publication of AU2001244727B2 publication Critical patent/AU2001244727B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2001244727A 2000-04-06 2001-04-05 Bile secretion promoting composition Ceased AU2001244727B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19489400P 2000-04-06 2000-04-06
US60/194,894 2000-04-06
PCT/JP2001/002938 WO2001076593A2 (en) 2000-04-06 2001-04-05 Bile secretion promoting composition a 15-keto prostaglandin

Publications (3)

Publication Number Publication Date
AU2001244727A1 AU2001244727A1 (en) 2002-01-10
AU2001244727A2 AU2001244727A2 (en) 2003-06-05
AU2001244727B2 true AU2001244727B2 (en) 2006-08-10

Family

ID=22719290

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001244727A Ceased AU2001244727B2 (en) 2000-04-06 2001-04-05 Bile secretion promoting composition
AU4472701A Pending AU4472701A (en) 2000-04-06 2001-04-05 Bile secretion promoting composition

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU4472701A Pending AU4472701A (en) 2000-04-06 2001-04-05 Bile secretion promoting composition

Country Status (15)

Country Link
US (2) US6469062B2 (enExample)
EP (1) EP1267883B1 (enExample)
JP (2) JP4183943B2 (enExample)
KR (1) KR100874626B1 (enExample)
CN (1) CN1241570C (enExample)
AR (1) AR030277A1 (enExample)
AT (1) ATE433754T1 (enExample)
AU (2) AU2001244727B2 (enExample)
BR (1) BR0107544A (enExample)
CA (1) CA2404767C (enExample)
DE (1) DE60139002D1 (enExample)
MX (1) MXPA02009915A (enExample)
NZ (1) NZ521784A (enExample)
TW (1) TWI232750B (enExample)
WO (1) WO2001076593A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60139002D1 (de) * 2000-04-06 2009-07-30 Sucampo Ag Gallensäurefördernde zusammensetzung für lebertransplantation welche ein 15-keto prostaglandin enthält
MXPA04002006A (es) 2001-08-31 2004-06-07 Sucampo Ag Analogos de prostagladina como abridor del canal de cloruro.
AR037524A1 (es) 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
US7732487B2 (en) 2001-11-19 2010-06-08 Sucampo Ag Method for treating a disease or condition responsive to opening of C1C-2 channel
ES2591252T3 (es) * 2002-12-27 2016-11-25 Sucampo Ag Derivados de prostaglandinas para tratar el síndrome de colon irritable y/o la dispepsia funcional
CN101198334B (zh) * 2005-04-12 2013-02-06 苏坎波公司 前列腺素化合物和质子泵抑制剂用于治疗肠胃病的联合应用
WO2007008697A2 (en) * 2005-07-08 2007-01-18 University Of Chicago Compositions and methods for refolding of denatured proteins
MX2008011148A (es) * 2006-02-28 2008-09-08 Sucampo Ag Metodo y composicion para tratar enfermedad pulmonar obstructiva cronica.
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
WO2018065826A1 (en) * 2016-10-06 2018-04-12 Sucampo Ag Multilayer beads for pharmaceutical use
KR102595299B1 (ko) 2020-10-12 2023-10-26 류형준 담즙 분비 촉진 효능이 있는 식품 조성물

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096927A (en) * 1989-10-20 1992-03-17 K.K. Ueno Seiyaku Oyo Kenkyujo Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
EP0690049B1 (en) * 1994-06-03 1999-08-04 R-Tech Ueno Ltd. Agent for treating hepato biliary diseases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58203911A (ja) * 1982-05-25 1983-11-28 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤
JPS6327433A (ja) 1986-07-21 1988-02-05 Teijin Ltd 肝疾患治療剤
CA1322749C (en) 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
US5166174A (en) 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
US5221763A (en) 1987-04-30 1993-06-22 R-Tech Ueno, Ltd. Prostaglandins of the F series
US5076569A (en) * 1989-09-15 1991-12-31 Gootter Steven M Contoured grip for exercising the hand
CA2039420C (en) 1990-04-04 1996-12-10 Ryuji Ueno Treatment of cataract with 15-keto-prostaglandin compounds
EP0455448B1 (en) * 1990-05-01 1998-12-09 R-Tech Ueno Ltd. Treatment of pancreatic disease with 15-keto-prostaglandin E compounds
JPH069404A (ja) 1992-06-23 1994-01-18 Ono Pharmaceut Co Ltd 臓器移植用薬剤
JP3183615B2 (ja) * 1994-06-03 2001-07-09 株式会社アールテック・ウエノ 肝・胆道系疾患処置剤
DE60139002D1 (de) * 2000-04-06 2009-07-30 Sucampo Ag Gallensäurefördernde zusammensetzung für lebertransplantation welche ein 15-keto prostaglandin enthält

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096927A (en) * 1989-10-20 1992-03-17 K.K. Ueno Seiyaku Oyo Kenkyujo Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
EP0424156B1 (en) * 1989-10-20 1996-01-10 R-Tech Ueno Ltd. Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
EP0690049B1 (en) * 1994-06-03 1999-08-04 R-Tech Ueno Ltd. Agent for treating hepato biliary diseases

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Beckh et al. Direct Regulation of Bile Secretion by Prostaglandins in Perfused Rat Liver (1994) Hepatology, vol 19(5), pg 1208-1213 *
Lou et al. Inhibition of Leukocyte Adherence and Transendothelial Migration in Cultured Human Liver Vascular Endothelial Cells by Prostaglandin E1 (1998) Hepatology, vol 27(3), pg 822-828 *

Also Published As

Publication number Publication date
NZ521784A (en) 2005-04-29
WO2001076593A2 (en) 2001-10-18
KR20020087123A (ko) 2002-11-21
AR030277A1 (es) 2003-08-20
US6469062B2 (en) 2002-10-22
CA2404767A1 (en) 2001-10-18
TWI232750B (en) 2005-05-21
WO2001076593A3 (en) 2002-07-11
JP2008291033A (ja) 2008-12-04
KR100874626B1 (ko) 2008-12-17
DE60139002D1 (de) 2009-07-30
CN1450899A (zh) 2003-10-22
CA2404767C (en) 2010-12-07
CN1241570C (zh) 2006-02-15
EP1267883A2 (en) 2003-01-02
JP4183943B2 (ja) 2008-11-19
EP1267883B1 (en) 2009-06-17
JP2004519412A (ja) 2004-07-02
US20030060506A1 (en) 2003-03-27
AU4472701A (en) 2001-10-23
US20020004524A1 (en) 2002-01-10
BR0107544A (pt) 2005-01-11
JP5073588B2 (ja) 2012-11-14
MXPA02009915A (es) 2003-03-27
ATE433754T1 (de) 2009-07-15

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Legal Events

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 09 JAN 2003

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired