AR030277A1 - Composicion promotora de la secrecion biliar y uso de 15-ceto-prostaglandina para producirla - Google Patents
Composicion promotora de la secrecion biliar y uso de 15-ceto-prostaglandina para producirlaInfo
- Publication number
- AR030277A1 AR030277A1 ARP010101663A ARP010101663A AR030277A1 AR 030277 A1 AR030277 A1 AR 030277A1 AR P010101663 A ARP010101663 A AR P010101663A AR P010101663 A ARP010101663 A AR P010101663A AR 030277 A1 AR030277 A1 AR 030277A1
- Authority
- AR
- Argentina
- Prior art keywords
- heterocyclic
- keto
- oxo
- aryl
- hydroxy
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000028327 secretion Effects 0.000 title abstract 2
- 230000001737 promoting effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 210000004185 liver Anatomy 0.000 abstract 3
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004104 aryloxy group Chemical group 0.000 abstract 2
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000004043 oxo group Chemical group O=* 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 210000000941 bile Anatomy 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003248 secreting effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
- A61K31/5585—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19489400P | 2000-04-06 | 2000-04-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR030277A1 true AR030277A1 (es) | 2003-08-20 |
Family
ID=22719290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010101663A AR030277A1 (es) | 2000-04-06 | 2001-04-06 | Composicion promotora de la secrecion biliar y uso de 15-ceto-prostaglandina para producirla |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US6469062B2 (enExample) |
| EP (1) | EP1267883B1 (enExample) |
| JP (2) | JP4183943B2 (enExample) |
| KR (1) | KR100874626B1 (enExample) |
| CN (1) | CN1241570C (enExample) |
| AR (1) | AR030277A1 (enExample) |
| AT (1) | ATE433754T1 (enExample) |
| AU (2) | AU2001244727B2 (enExample) |
| BR (1) | BR0107544A (enExample) |
| CA (1) | CA2404767C (enExample) |
| DE (1) | DE60139002D1 (enExample) |
| MX (1) | MXPA02009915A (enExample) |
| NZ (1) | NZ521784A (enExample) |
| TW (1) | TWI232750B (enExample) |
| WO (1) | WO2001076593A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE433754T1 (de) * | 2000-04-06 | 2009-07-15 | Sucampo Ag | Gallensäurefördernde zusammensetzung für lebertransplantation welche ein 15-keto prostaglandin enthält |
| JP4786866B2 (ja) | 2001-08-31 | 2011-10-05 | スキャンポ・アーゲー | クロライドチャンネルオープナーとしてのプロスタグランジンアナログ |
| AR037524A1 (es) | 2001-11-14 | 2004-11-17 | Sucampo Ag | Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion |
| US7732487B2 (en) * | 2001-11-19 | 2010-06-08 | Sucampo Ag | Method for treating a disease or condition responsive to opening of C1C-2 channel |
| JP4889219B2 (ja) | 2002-12-27 | 2012-03-07 | スキャンポ・アーゲー | 腹部不快感の処置のためのプロスタグランジン誘導体 |
| KR101466980B1 (ko) * | 2005-04-12 | 2014-12-01 | 수캄포 아게 | 위장 장애 치료를 위한 프로스타글란딘 화합물과 양성자펌프 억제제의 병용 |
| WO2007008697A2 (en) * | 2005-07-08 | 2007-01-18 | University Of Chicago | Compositions and methods for refolding of denatured proteins |
| JP5377970B2 (ja) * | 2006-02-28 | 2013-12-25 | スキャンポ・アーゲー | 慢性閉塞性肺疾患を処置するための方法および組成物 |
| WO2014159679A1 (en) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for using lubiprostone to absorb fluid from the subretinal space |
| US11534404B2 (en) | 2016-10-06 | 2022-12-27 | Sucampo Ag | Multilayer beads for pharmaceutical use |
| KR102595299B1 (ko) | 2020-10-12 | 2023-10-26 | 류형준 | 담즙 분비 촉진 효능이 있는 식품 조성물 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58203911A (ja) * | 1982-05-25 | 1983-11-28 | Ono Pharmaceut Co Ltd | プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤 |
| JPS6327433A (ja) | 1986-07-21 | 1988-02-05 | Teijin Ltd | 肝疾患治療剤 |
| US5166174A (en) | 1987-01-28 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti-ulcers containing same |
| CA1322749C (en) | 1987-01-28 | 1993-10-05 | Ryuzo Ueno | Prostaglandins of the d series, and tranquilizers and soporifics containing the same |
| US5221763A (en) | 1987-04-30 | 1993-06-22 | R-Tech Ueno, Ltd. | Prostaglandins of the F series |
| US5076569A (en) * | 1989-09-15 | 1991-12-31 | Gootter Steven M | Contoured grip for exercising the hand |
| CA2027814C (en) * | 1989-10-20 | 1996-07-30 | Ryuji Ueno | Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds |
| TW249226B (enExample) | 1990-04-04 | 1995-06-11 | Aderk Ueno Kk | |
| DE69130586T2 (de) * | 1990-05-01 | 1999-06-17 | R-Tech Ueno, Ltd., Osaka | Behandlung von Pankreaskrankheit mit 15-keto-Prostaglandin E-Derivaten |
| JPH069404A (ja) | 1992-06-23 | 1994-01-18 | Ono Pharmaceut Co Ltd | 臓器移植用薬剤 |
| JP3183615B2 (ja) * | 1994-06-03 | 2001-07-09 | 株式会社アールテック・ウエノ | 肝・胆道系疾患処置剤 |
| CA2150287C (en) * | 1994-06-03 | 2004-08-10 | Ryuji Ueno | Agent for treating hepato-biliary diseases |
| ATE433754T1 (de) * | 2000-04-06 | 2009-07-15 | Sucampo Ag | Gallensäurefördernde zusammensetzung für lebertransplantation welche ein 15-keto prostaglandin enthält |
-
2001
- 2001-04-05 AT AT01917828T patent/ATE433754T1/de not_active IP Right Cessation
- 2001-04-05 MX MXPA02009915A patent/MXPA02009915A/es active IP Right Grant
- 2001-04-05 NZ NZ521784A patent/NZ521784A/en not_active IP Right Cessation
- 2001-04-05 WO PCT/JP2001/002938 patent/WO2001076593A2/en not_active Ceased
- 2001-04-05 CA CA2404767A patent/CA2404767C/en not_active Expired - Fee Related
- 2001-04-05 JP JP2001574111A patent/JP4183943B2/ja not_active Expired - Fee Related
- 2001-04-05 BR BR0107544-6A patent/BR0107544A/pt not_active Application Discontinuation
- 2001-04-05 KR KR1020027013275A patent/KR100874626B1/ko not_active Expired - Fee Related
- 2001-04-05 DE DE60139002T patent/DE60139002D1/de not_active Expired - Lifetime
- 2001-04-05 AU AU2001244727A patent/AU2001244727B2/en not_active Ceased
- 2001-04-05 CN CNB018105831A patent/CN1241570C/zh not_active Expired - Fee Related
- 2001-04-05 AU AU4472701A patent/AU4472701A/xx active Pending
- 2001-04-05 EP EP01917828A patent/EP1267883B1/en not_active Expired - Lifetime
- 2001-04-06 US US09/827,375 patent/US6469062B2/en not_active Expired - Lifetime
- 2001-04-06 TW TW090108254A patent/TWI232750B/zh not_active IP Right Cessation
- 2001-04-06 AR ARP010101663A patent/AR030277A1/es not_active Application Discontinuation
-
2002
- 2002-07-18 US US10/197,403 patent/US20030060506A1/en not_active Abandoned
-
2008
- 2008-06-05 JP JP2008148107A patent/JP5073588B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| TWI232750B (en) | 2005-05-21 |
| KR20020087123A (ko) | 2002-11-21 |
| US20030060506A1 (en) | 2003-03-27 |
| WO2001076593A2 (en) | 2001-10-18 |
| ATE433754T1 (de) | 2009-07-15 |
| KR100874626B1 (ko) | 2008-12-17 |
| CA2404767A1 (en) | 2001-10-18 |
| EP1267883B1 (en) | 2009-06-17 |
| CA2404767C (en) | 2010-12-07 |
| JP2004519412A (ja) | 2004-07-02 |
| JP4183943B2 (ja) | 2008-11-19 |
| US6469062B2 (en) | 2002-10-22 |
| CN1241570C (zh) | 2006-02-15 |
| JP2008291033A (ja) | 2008-12-04 |
| NZ521784A (en) | 2005-04-29 |
| WO2001076593A3 (en) | 2002-07-11 |
| BR0107544A (pt) | 2005-01-11 |
| JP5073588B2 (ja) | 2012-11-14 |
| EP1267883A2 (en) | 2003-01-02 |
| DE60139002D1 (de) | 2009-07-30 |
| AU4472701A (en) | 2001-10-23 |
| US20020004524A1 (en) | 2002-01-10 |
| CN1450899A (zh) | 2003-10-22 |
| MXPA02009915A (es) | 2003-03-27 |
| AU2001244727B2 (en) | 2006-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |