JP4153878B2 - Ｇｔ遺伝子が除去された複製豚及びその生産方法 - Google Patents

Ｇｔ遺伝子が除去された複製豚及びその生産方法 Download PDF

Info

Publication number
JP4153878B2
JP4153878B2 JP2003586344A JP2003586344A JP4153878B2 JP 4153878 B2 JP4153878 B2 JP 4153878B2 JP 2003586344 A JP2003586344 A JP 2003586344A JP 2003586344 A JP2003586344 A JP 2003586344A JP 4153878 B2 JP4153878 B2 JP 4153878B2
Authority
JP
Japan
Prior art keywords
gene
pig
nuclear
cells
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2003586344A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005519633A (ja
JP2005519633A5 (https=
Inventor
スク ファン，ウー
チョン リー，ビョン
クン カン，ソン
ヨン ハン，ジェ
ムック リム，ジョン
キュ リー，チャン
ソン リー，ウン
ベー ジョン，ウ
キ チョ，ゾン
ヨン キム，デ
ファン ヒョン，サン
サン リー，カップ
ソー キム，ヒュ
ヒュン リー，ソ
チョル リー，ソン
チョン ヨム，ス
Original Assignee
ソウル ナショナル ユニバーシティー インダストリー ファウンデーション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ソウル ナショナル ユニバーシティー インダストリー ファウンデーション filed Critical ソウル ナショナル ユニバーシティー インダストリー ファウンデーション
Publication of JP2005519633A publication Critical patent/JP2005519633A/ja
Publication of JP2005519633A5 publication Critical patent/JP2005519633A5/ja
Application granted granted Critical
Publication of JP4153878B2 publication Critical patent/JP4153878B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8778—Swine embryos

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2003586344A 2001-12-29 2001-12-29 Ｇｔ遺伝子が除去された複製豚及びその生産方法 Expired - Fee Related JP4153878B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2001/002304 WO2003089632A1 (en) 2001-12-29 2001-12-29 Gfp-transfected clon pig, gt knock-out clon pig and methods for production thereof

Publications (3)

Publication Number Publication Date
JP2005519633A JP2005519633A (ja) 2005-07-07
JP2005519633A5 JP2005519633A5 (https=) 2005-12-22
JP4153878B2 true JP4153878B2 (ja) 2008-09-24

Family

ID=29244661

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003586344A Expired - Fee Related JP4153878B2 (ja) 2001-12-29 2001-12-29 Ｇｔ遺伝子が除去された複製豚及びその生産方法

Country Status (7)

Country Link
US (2) US20050076399A1 (https=)
EP (1) EP1465986A4 (https=)
JP (1) JP4153878B2 (https=)
CN (1) CN1582332A (https=)
AU (1) AU2002217606A1 (https=)
CA (1) CA2472040A1 (https=)
WO (1) WO2003089632A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7912696B1 (en) 1998-08-31 2011-03-22 Sony Corporation Natural language processing apparatus and natural language processing method
WO2014178485A1 (ko) 2013-04-30 2014-11-06 건국대학교 산학협력단 Ｃｍｐ-아세틸뉴라미닌산 히드록실라아제 타겟팅 벡터, 그 벡터가 도입된 이종간 이식용 형질전환 동물 및 그 제조방법

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005009134A1 (en) 2003-07-21 2005-02-03 Lifecell Corporation ACELLULAR TISSUE MATRICES MADE FROM GALACTOSE α-1,3-GALACTOSE-DEFICIENT TISSUE
NZ554824A (en) * 2004-10-22 2010-10-29 Revivicor Inc Porcines that lack endogenous antibody chains and express exogenous immunoglobulins
JP2006129736A (ja) * 2004-11-02 2006-05-25 Nippon Dobutsu Kogaku Kenkyusho:Kk 異種移植用豚細胞、その選抜方法及び異種移植用豚
US20060148080A1 (en) * 2004-12-30 2006-07-06 Paul Diamond Methods for supporting and producing human cells and tissues in non-human mammal hosts
US20060147429A1 (en) * 2004-12-30 2006-07-06 Paul Diamond Facilitated cellular reconstitution of organs and tissues
CN100404675C (zh) * 2006-02-22 2008-07-23 李宁 一种生产体细胞克隆猪的方法
CN101805402B (zh) * 2007-06-28 2012-10-03 北京大学 抗阿片肽的一种活性片段
CN101798338B (zh) * 2007-06-28 2012-10-03 北京大学 一种抗阿片肽的拮抗肽与该拮抗肽的应用
CN103492576A (zh) 2011-02-14 2014-01-01 雷维维科公司 用于血管化异种移植物及其衍生物的异种移植的遗传修饰的猪
EP3065790B1 (en) 2013-11-04 2020-10-28 LifeCell Corporation Methods of removing alpha-galactose
CN106172237B (zh) * 2016-08-08 2019-05-10 贵州大学 Ghr基因敲除纯合香猪的选育方法
KR102176161B1 (ko) * 2019-07-23 2020-11-09 주식회사 옵티팜 돼지 내인성 레트로바이러스 Envlope C 음성, GGTA1, CMAH, iGb3s, β4GalNT2 유전자가 넉아웃되고, 인간 CD46 및 TBM 유전자를 발현하는 이종장기이식을 위한 형질전환 복제돼지 및 이의 제조방법
CN111955422A (zh) * 2020-08-21 2020-11-20 五邑大学 一种可用于异种器官移植的供体猪的构建方法
CN116411022B (zh) * 2022-11-21 2024-06-21 华中农业大学 一种指示猪体细胞克隆胚胎基因组激活程度的载体及细胞

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960705209A (ko) * 1993-09-10 1996-10-09 잭 엠. 그랜노위츠 녹색 형광 단백의 용도
US5576201A (en) * 1994-01-14 1996-11-19 Alexion Pharmaceuticals, Inc. Retroviral vector particles for transducing non-proliferating cells
US6235969B1 (en) * 1997-01-10 2001-05-22 University Of Massachusetts Cloning pigs using donor nuclei from non-quiescent differentiated cells
US6258998B1 (en) * 1998-11-24 2001-07-10 Infigen, Inc. Method of cloning porcine animals
US6700037B2 (en) * 1998-11-24 2004-03-02 Infigen, Inc. Method of cloning porcine animals
WO2001000795A1 (en) * 1999-06-30 2001-01-04 Hwang, Woo-Suk A method for producing cloned cows
AU753209B2 (en) * 1999-06-30 2002-10-10 Seoul National University Industry Foundation Method for producing cloned tigers by employing inter-species nuclear transplantation technique
US20010044937A1 (en) * 1999-12-17 2001-11-22 Gerald Schatten Methods for producing transgenic animals
JP5580505B2 (ja) * 2001-08-30 2014-08-27 ディスカヴァーエックス コーポレイション 遺伝子構築細胞モニターシステム
US7547816B2 (en) * 2001-12-21 2009-06-16 The Curators Of The University Of Missouri α(1,3)-galactosyltransferase knockout swine, tissues and organs

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7912696B1 (en) 1998-08-31 2011-03-22 Sony Corporation Natural language processing apparatus and natural language processing method
WO2014178485A1 (ko) 2013-04-30 2014-11-06 건국대학교 산학협력단 Ｃｍｐ-아세틸뉴라미닌산 히드록실라아제 타겟팅 벡터, 그 벡터가 도입된 이종간 이식용 형질전환 동물 및 그 제조방법

Also Published As

Publication number Publication date
WO2003089632A1 (en) 2003-10-30
EP1465986A1 (en) 2004-10-13
CA2472040A1 (en) 2003-10-30
CN1582332A (zh) 2005-02-16
US20050076399A1 (en) 2005-04-07
AU2002217606A1 (en) 2003-11-03
JP2005519633A (ja) 2005-07-07
EP1465986A4 (en) 2005-01-26
US20100115641A1 (en) 2010-05-06

Similar Documents

Publication Publication Date Title
US20100115641A1 (en) Gfp-transfected clon pig, gt knock-out clon pig and methods for productions thereof
RU2216592C2 (ru) Способ получения эмбрионов животных и способ выращивания животного из эмбрионов
JP2002511732A (ja) トランスジェニック動物を発生させるための組成物および方法
US20190032086A1 (en) Method for preparing a gene knock-out canine with somatic cell cloning technology
JP5817955B2 (ja) 血友病ａモデルブタの作出
KR100733012B1 (ko) 복제된 개과 동물 및 이의 생산 방법
Singh et al. Biotechnology in livestock reproduction
JP2010517563A (ja) イヌ科動物の体細胞核移植産子の生産効率を向上させる方法
JP5145553B2 (ja) ＥｎｄｏＧａｌＣ−ｈＤＡＦダブルトランスジェニックブタ
JP2011508600A (ja) 形質転換された複製犬の生産方法
KR101763343B1 (ko) 체세포 또는 줄기세포의 핵 이식을 이용한 복제개의 생산방법
KR100829426B1 (ko) 복제개의 생산 방법
KR101025707B1 (ko) 사람 알파1-안티트립신을 생산하는 형질전환 복제소 및이것의 생산 방법
US7351876B2 (en) Efficient nuclear transfer with primordial gametes
KR20040074108A (ko) 지에프피 유전자가 발현되는 돼지, 또는 지티 유전자가제거된 복제돼지 및 이들의 생산방법
AU747070B2 (en) Efficient nuclear transfer using primordial germ cells
KR20090115081A (ko) 개과 동물의 복제 생산 방법
KR101832485B1 (ko) 목적유전자를 조건적으로 발현하는 복제된 개과동물의 생산방법
KR20100081805A (ko) 체세포 또는 줄기세포의 핵 이식을 이용한 복제개의 생산방법
KR100824218B1 (ko) 복제늑대의 생산방법
CN115960958A (zh) 一种改变猫毛色的遗传修饰方法
JP2004016115A (ja) 効率的に体細胞から動物個体を生産する方法
Spell et al. 15 Somatic Cell Cloning in the Beef
KR20040016426A (ko) 사람 프로유로키나제를 생산하는 형질전환 복제 소 및이의 생산 방법

Legal Events

Date Code Title Description
A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20061219

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070219

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20070731

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20071025

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20071025

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20071025

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20071203

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20071227

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20080109

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080131

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20080617

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20080704

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110711

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110711

Year of fee payment: 3

LAPS Cancellation because of no payment of annual fees