CN1582332A - 转染gfp的克隆猪、敲除gt的克隆猪及其生产方法 - Google Patents

转染gfp的克隆猪、敲除gt的克隆猪及其生产方法 Download PDF

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Publication number
CN1582332A
CN1582332A CNA018239196A CN01823919A CN1582332A CN 1582332 A CN1582332 A CN 1582332A CN A018239196 A CNA018239196 A CN A018239196A CN 01823919 A CN01823919 A CN 01823919A CN 1582332 A CN1582332 A CN 1582332A
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gene
pig
porcine
gfp
nuclear
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Chinese (zh)
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黄寓锡
李柄千
姜成根
韩在容
林正默
李昌奎
李殷松
郑义培
赵钟基
金大暎
玄尚桓
李甲相
金惠洙
李昭炫
李成哲
廉受清
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Seoul National University Industry Foundation
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Seoul National University Industry Foundation
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8778—Swine embryos

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
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  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CNA018239196A 2001-12-29 2001-12-29 转染gfp的克隆猪、敲除gt的克隆猪及其生产方法 Pending CN1582332A (zh)

Applications Claiming Priority (1)

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PCT/KR2001/002304 WO2003089632A1 (en) 2001-12-29 2001-12-29 Gfp-transfected clon pig, gt knock-out clon pig and methods for production thereof

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CN1582332A true CN1582332A (zh) 2005-02-16

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CNA018239196A Pending CN1582332A (zh) 2001-12-29 2001-12-29 转染gfp的克隆猪、敲除gt的克隆猪及其生产方法

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US (2) US20050076399A1 (https=)
EP (1) EP1465986A4 (https=)
JP (1) JP4153878B2 (https=)
CN (1) CN1582332A (https=)
AU (1) AU2002217606A1 (https=)
CA (1) CA2472040A1 (https=)
WO (1) WO2003089632A1 (https=)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100404675C (zh) * 2006-02-22 2008-07-23 李宁 一种生产体细胞克隆猪的方法
CN101805402B (zh) * 2007-06-28 2012-10-03 北京大学 抗阿片肽的一种活性片段
CN101798338B (zh) * 2007-06-28 2012-10-03 北京大学 一种抗阿片肽的拮抗肽与该拮抗肽的应用
CN104774871A (zh) * 2011-02-14 2015-07-15 雷维维科公司 用于血管化异种移植物及其衍生物的异种移植的遗传修饰的猪
CN106172237A (zh) * 2016-08-08 2016-12-07 贵州大学 Ghr基因敲除纯合香猪的选育方法
CN111955422A (zh) * 2020-08-21 2020-11-20 五邑大学 一种可用于异种器官移植的供体猪的构建方法
CN115003817A (zh) * 2019-07-23 2022-09-02 致优制药有限公司 猪内源性逆转录病毒包膜C为阴性、GGTA1、CMAH、iGb3s及β4GalNT2基因被敲除并且表达人类CD46及TBM基因的异种器官移植用转基因克隆猪及其制备方法

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WO2000013102A1 (en) 1998-08-31 2000-03-09 Sony Corporation Natural language processing device and method
WO2005009134A1 (en) 2003-07-21 2005-02-03 Lifecell Corporation ACELLULAR TISSUE MATRICES MADE FROM GALACTOSE α-1,3-GALACTOSE-DEFICIENT TISSUE
NZ554824A (en) * 2004-10-22 2010-10-29 Revivicor Inc Porcines that lack endogenous antibody chains and express exogenous immunoglobulins
JP2006129736A (ja) * 2004-11-02 2006-05-25 Nippon Dobutsu Kogaku Kenkyusho:Kk 異種移植用豚細胞、その選抜方法及び異種移植用豚
US20060148080A1 (en) * 2004-12-30 2006-07-06 Paul Diamond Methods for supporting and producing human cells and tissues in non-human mammal hosts
US20060147429A1 (en) * 2004-12-30 2006-07-06 Paul Diamond Facilitated cellular reconstitution of organs and tissues
DK2993234T3 (en) 2013-04-30 2019-01-07 Univ Konkuk Ind Coop Corp Vector Targeted CMP Acetylneuramic Acid Hydroxylase, Transgenic Animal for Xenotransplantation Introduced with the Vector and Method of Preparation thereof
EP3065790B1 (en) 2013-11-04 2020-10-28 LifeCell Corporation Methods of removing alpha-galactose
CN116411022B (zh) * 2022-11-21 2024-06-21 华中农业大学 一种指示猪体细胞克隆胚胎基因组激活程度的载体及细胞

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960705209A (ko) * 1993-09-10 1996-10-09 잭 엠. 그랜노위츠 녹색 형광 단백의 용도
US5576201A (en) * 1994-01-14 1996-11-19 Alexion Pharmaceuticals, Inc. Retroviral vector particles for transducing non-proliferating cells
US6235969B1 (en) * 1997-01-10 2001-05-22 University Of Massachusetts Cloning pigs using donor nuclei from non-quiescent differentiated cells
US6258998B1 (en) * 1998-11-24 2001-07-10 Infigen, Inc. Method of cloning porcine animals
US6700037B2 (en) * 1998-11-24 2004-03-02 Infigen, Inc. Method of cloning porcine animals
WO2001000795A1 (en) * 1999-06-30 2001-01-04 Hwang, Woo-Suk A method for producing cloned cows
AU753209B2 (en) * 1999-06-30 2002-10-10 Seoul National University Industry Foundation Method for producing cloned tigers by employing inter-species nuclear transplantation technique
US20010044937A1 (en) * 1999-12-17 2001-11-22 Gerald Schatten Methods for producing transgenic animals
JP5580505B2 (ja) * 2001-08-30 2014-08-27 ディスカヴァーエックス コーポレイション 遺伝子構築細胞モニターシステム
US7547816B2 (en) * 2001-12-21 2009-06-16 The Curators Of The University Of Missouri α(1,3)-galactosyltransferase knockout swine, tissues and organs

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100404675C (zh) * 2006-02-22 2008-07-23 李宁 一种生产体细胞克隆猪的方法
CN101805402B (zh) * 2007-06-28 2012-10-03 北京大学 抗阿片肽的一种活性片段
CN101798338B (zh) * 2007-06-28 2012-10-03 北京大学 一种抗阿片肽的拮抗肽与该拮抗肽的应用
CN104774871A (zh) * 2011-02-14 2015-07-15 雷维维科公司 用于血管化异种移植物及其衍生物的异种移植的遗传修饰的猪
US11179496B2 (en) 2011-02-14 2021-11-23 Revivicor, Inc. Genetically modified pigs for xenotransplantation of vascularized xenografts and derivatives thereof
US12569592B2 (en) 2011-02-14 2026-03-10 Revivicor, Inc. Genetically modified pigs for xenotransplantation of vascularized xenografts and derivatives thereof
CN106172237A (zh) * 2016-08-08 2016-12-07 贵州大学 Ghr基因敲除纯合香猪的选育方法
CN106172237B (zh) * 2016-08-08 2019-05-10 贵州大学 Ghr基因敲除纯合香猪的选育方法
CN115003817A (zh) * 2019-07-23 2022-09-02 致优制药有限公司 猪内源性逆转录病毒包膜C为阴性、GGTA1、CMAH、iGb3s及β4GalNT2基因被敲除并且表达人类CD46及TBM基因的异种器官移植用转基因克隆猪及其制备方法
CN111955422A (zh) * 2020-08-21 2020-11-20 五邑大学 一种可用于异种器官移植的供体猪的构建方法

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Publication number Publication date
WO2003089632A1 (en) 2003-10-30
EP1465986A1 (en) 2004-10-13
CA2472040A1 (en) 2003-10-30
US20050076399A1 (en) 2005-04-07
AU2002217606A1 (en) 2003-11-03
JP4153878B2 (ja) 2008-09-24
JP2005519633A (ja) 2005-07-07
EP1465986A4 (en) 2005-01-26
US20100115641A1 (en) 2010-05-06

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