JP4128453B2 - 新規分子機能の進化 - Google Patents

新規分子機能の進化 Download PDF

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Publication number
JP4128453B2
JP4128453B2 JP2002574322A JP2002574322A JP4128453B2 JP 4128453 B2 JP4128453 B2 JP 4128453B2 JP 2002574322 A JP2002574322 A JP 2002574322A JP 2002574322 A JP2002574322 A JP 2002574322A JP 4128453 B2 JP4128453 B2 JP 4128453B2
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template
sequence
oligonucleotide
dna
reactive
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Japanese (ja)
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JP2004536162A (ja
JP2004536162A5 (enExample
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デイビッド アール． リウ，
ゼヴ ジェイ． ガートナー，
マシュー ダブリュー． カナン，
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Harvard University
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Harvard University
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Steroid Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Peptides Or Proteins (AREA)
JP2002574322A 2001-03-19 2002-03-19 新規分子機能の進化 Expired - Fee Related JP4128453B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27709401P 2001-03-19 2001-03-19
US27708101P 2001-03-19 2001-03-19
US30669101P 2001-07-20 2001-07-20
PCT/US2002/008546 WO2002074929A2 (en) 2001-03-19 2002-03-19 Evolving new molecular function
US10/101,030 US7070928B2 (en) 2001-03-19 2002-03-19 Evolving new molecular function

Related Child Applications (1)

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JP2008042250A Division JP4384229B2 (ja) 2001-03-19 2008-02-22 新規分子機能の進化

Publications (3)

Publication Number Publication Date
JP2004536162A JP2004536162A (ja) 2004-12-02
JP2004536162A5 JP2004536162A5 (enExample) 2006-01-12
JP4128453B2 true JP4128453B2 (ja) 2008-07-30

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JP2002574322A Expired - Fee Related JP4128453B2 (ja) 2001-03-19 2002-03-19 新規分子機能の進化
JP2008042250A Expired - Fee Related JP4384229B2 (ja) 2001-03-19 2008-02-22 新規分子機能の進化
JP2009169425A Withdrawn JP2009232869A (ja) 2001-03-19 2009-07-17 新規分子機能の進化
JP2012165977A Expired - Fee Related JP5509270B2 (ja) 2001-03-19 2012-07-26 新規分子機能の進化

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JP2008042250A Expired - Fee Related JP4384229B2 (ja) 2001-03-19 2008-02-22 新規分子機能の進化
JP2009169425A Withdrawn JP2009232869A (ja) 2001-03-19 2009-07-17 新規分子機能の進化
JP2012165977A Expired - Fee Related JP5509270B2 (ja) 2001-03-19 2012-07-26 新規分子機能の進化

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US (7) US7070928B2 (enExample)
EP (3) EP1832567A3 (enExample)
JP (4) JP4128453B2 (enExample)
AT (1) ATE335754T1 (enExample)
AU (2) AU2002306777C1 (enExample)
CA (1) CA2441820C (enExample)
DE (1) DE60213826T3 (enExample)
DK (1) DK1423400T4 (enExample)
ES (1) ES2271306T5 (enExample)
IL (4) IL158000A0 (enExample)
PT (1) PT1423400E (enExample)
WO (1) WO2002074929A2 (enExample)

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