JP3796351B2 - パロキセチン塩酸塩無水和物の乾燥方法 - Google Patents

パロキセチン塩酸塩無水和物の乾燥方法 Download PDF

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Publication number
JP3796351B2
JP3796351B2 JP10105898A JP10105898A JP3796351B2 JP 3796351 B2 JP3796351 B2 JP 3796351B2 JP 10105898 A JP10105898 A JP 10105898A JP 10105898 A JP10105898 A JP 10105898A JP 3796351 B2 JP3796351 B2 JP 3796351B2
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JP
Japan
Prior art keywords
isopropyl alcohol
paroxetine hydrochloride
drying
paroxetine
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP10105898A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001072677A (ja
JP2001072677A5 (enExample
Inventor
充 岡竹
太郎 石橋
義弘 河田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP10105898A priority Critical patent/JP3796351B2/ja
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to PCT/JP1999/001914 priority patent/WO1999052902A1/ja
Priority to PT99945685T priority patent/PT990655E/pt
Priority to CA002294716A priority patent/CA2294716C/en
Priority to AT99945685T priority patent/ATE244237T1/de
Priority to EP99945685A priority patent/EP0990655B1/en
Priority to AU52656/99A priority patent/AU730652B2/en
Priority to DE69909207T priority patent/DE69909207T2/de
Priority to US09/445,598 priority patent/US6541637B1/en
Priority to ES99945685T priority patent/ES2199592T3/es
Publication of JP2001072677A publication Critical patent/JP2001072677A/ja
Publication of JP2001072677A5 publication Critical patent/JP2001072677A5/ja
Application granted granted Critical
Publication of JP3796351B2 publication Critical patent/JP3796351B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP10105898A 1998-04-13 1998-04-13 パロキセチン塩酸塩無水和物の乾燥方法 Expired - Fee Related JP3796351B2 (ja)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP10105898A JP3796351B2 (ja) 1998-04-13 1998-04-13 パロキセチン塩酸塩無水和物の乾燥方法
US09/445,598 US6541637B1 (en) 1998-04-13 1999-04-12 Method for drying anhydrous paroxetine hydrochloride
CA002294716A CA2294716C (en) 1998-04-13 1999-04-12 Method for drying anhydrous paroxetine hydrochloride
AT99945685T ATE244237T1 (de) 1998-04-13 1999-04-12 Verfahren zur trocknung von paroxetinhydrochlorid
EP99945685A EP0990655B1 (en) 1998-04-13 1999-04-12 Method for drying anhydrous paroxetine hydrochloride
AU52656/99A AU730652B2 (en) 1998-04-13 1999-04-12 Method for drying anhydrous paroxetine hydrochloride
PCT/JP1999/001914 WO1999052902A1 (en) 1998-04-13 1999-04-12 Method for drying anhydrous paroxetine hydrochloride
PT99945685T PT990655E (pt) 1998-04-13 1999-04-12 Metodo de secagem de cloridrato de paroxetina anidro
ES99945685T ES2199592T3 (es) 1998-04-13 1999-04-12 Procedimiento para secar hidrocloruro de paroxetina anhidro.
DE69909207T DE69909207T2 (de) 1998-04-13 1999-04-12 Verfahren zur trocknung von paroxetinhydrochlorid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10105898A JP3796351B2 (ja) 1998-04-13 1998-04-13 パロキセチン塩酸塩無水和物の乾燥方法

Publications (3)

Publication Number Publication Date
JP2001072677A JP2001072677A (ja) 2001-03-21
JP2001072677A5 JP2001072677A5 (enExample) 2005-02-03
JP3796351B2 true JP3796351B2 (ja) 2006-07-12

Family

ID=14290525

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10105898A Expired - Fee Related JP3796351B2 (ja) 1998-04-13 1998-04-13 パロキセチン塩酸塩無水和物の乾燥方法

Country Status (10)

Country Link
US (1) US6541637B1 (enExample)
EP (1) EP0990655B1 (enExample)
JP (1) JP3796351B2 (enExample)
AT (1) ATE244237T1 (enExample)
AU (1) AU730652B2 (enExample)
CA (1) CA2294716C (enExample)
DE (1) DE69909207T2 (enExample)
ES (1) ES2199592T3 (enExample)
PT (1) PT990655E (enExample)
WO (1) WO1999052902A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1394160A1 (en) 1996-06-13 2004-03-03 SUMIKA FINE CHEMICALS Co., Ltd. Process for preparing crystalline paroxetin hydrochloride
DK1100796T3 (da) * 1998-08-07 2003-08-25 Smithkline Beecham Plc Fremgangsmåde til fremstilling af en ikke-krystallinsk anhydratform af paroxetinhydrochlorid
GB9826176D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
US20080033050A1 (en) * 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK283608B6 (sk) 1995-02-06 2003-10-07 Smithkline Beecham Plc Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie
US5856493A (en) * 1995-02-06 1999-01-05 Smithkline Beecham Corporation Process for making novel form of paroxeting hydrochloride anhydrate
EP1394160A1 (en) * 1996-06-13 2004-03-03 SUMIKA FINE CHEMICALS Co., Ltd. Process for preparing crystalline paroxetin hydrochloride
JP3819532B2 (ja) 1996-06-13 2006-09-13 住友化学株式会社 ピペリジン誘導体およびその製造方法
DK1100796T3 (da) * 1998-08-07 2003-08-25 Smithkline Beecham Plc Fremgangsmåde til fremstilling af en ikke-krystallinsk anhydratform af paroxetinhydrochlorid

Also Published As

Publication number Publication date
EP0990655A1 (en) 2000-04-05
JP2001072677A (ja) 2001-03-21
EP0990655A4 (en) 2001-10-04
PT990655E (pt) 2003-11-28
CA2294716A1 (en) 1999-10-21
ES2199592T3 (es) 2004-02-16
ATE244237T1 (de) 2003-07-15
AU730652B2 (en) 2001-03-08
DE69909207D1 (de) 2003-08-07
CA2294716C (en) 2004-08-03
DE69909207T2 (de) 2004-04-22
EP0990655B1 (en) 2003-07-02
AU5265699A (en) 1999-11-01
WO1999052902A1 (en) 1999-10-21
US6541637B1 (en) 2003-04-01

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