CA2294716C - Method for drying anhydrous paroxetine hydrochloride - Google Patents

Method for drying anhydrous paroxetine hydrochloride Download PDF

Info

Publication number
CA2294716C
CA2294716C CA002294716A CA2294716A CA2294716C CA 2294716 C CA2294716 C CA 2294716C CA 002294716 A CA002294716 A CA 002294716A CA 2294716 A CA2294716 A CA 2294716A CA 2294716 C CA2294716 C CA 2294716C
Authority
CA
Canada
Prior art keywords
paroxetine hydrochloride
isopropyl alcohol
drying
weight
anhydrite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002294716A
Other languages
English (en)
French (fr)
Other versions
CA2294716A1 (en
Inventor
Mitsuru Okatake
Taro Ishibashi
Yoshihiro Kawata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumika Fine Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumika Fine Chemicals Co Ltd filed Critical Sumika Fine Chemicals Co Ltd
Publication of CA2294716A1 publication Critical patent/CA2294716A1/en
Application granted granted Critical
Publication of CA2294716C publication Critical patent/CA2294716C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002294716A 1998-04-13 1999-04-12 Method for drying anhydrous paroxetine hydrochloride Expired - Fee Related CA2294716C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10105898A JP3796351B2 (ja) 1998-04-13 1998-04-13 パロキセチン塩酸塩無水和物の乾燥方法
JP10/101058 1998-04-13
PCT/JP1999/001914 WO1999052902A1 (en) 1998-04-13 1999-04-12 Method for drying anhydrous paroxetine hydrochloride

Publications (2)

Publication Number Publication Date
CA2294716A1 CA2294716A1 (en) 1999-10-21
CA2294716C true CA2294716C (en) 2004-08-03

Family

ID=14290525

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002294716A Expired - Fee Related CA2294716C (en) 1998-04-13 1999-04-12 Method for drying anhydrous paroxetine hydrochloride

Country Status (10)

Country Link
US (1) US6541637B1 (enExample)
EP (1) EP0990655B1 (enExample)
JP (1) JP3796351B2 (enExample)
AT (1) ATE244237T1 (enExample)
AU (1) AU730652B2 (enExample)
CA (1) CA2294716C (enExample)
DE (1) DE69909207T2 (enExample)
ES (1) ES2199592T3 (enExample)
PT (1) PT990655E (enExample)
WO (1) WO1999052902A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1394160A1 (en) 1996-06-13 2004-03-03 SUMIKA FINE CHEMICALS Co., Ltd. Process for preparing crystalline paroxetin hydrochloride
DK1100796T3 (da) * 1998-08-07 2003-08-25 Smithkline Beecham Plc Fremgangsmåde til fremstilling af en ikke-krystallinsk anhydratform af paroxetinhydrochlorid
GB9826176D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
US20080033050A1 (en) * 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK283608B6 (sk) 1995-02-06 2003-10-07 Smithkline Beecham Plc Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie
US5856493A (en) * 1995-02-06 1999-01-05 Smithkline Beecham Corporation Process for making novel form of paroxeting hydrochloride anhydrate
EP1394160A1 (en) * 1996-06-13 2004-03-03 SUMIKA FINE CHEMICALS Co., Ltd. Process for preparing crystalline paroxetin hydrochloride
JP3819532B2 (ja) 1996-06-13 2006-09-13 住友化学株式会社 ピペリジン誘導体およびその製造方法
DK1100796T3 (da) * 1998-08-07 2003-08-25 Smithkline Beecham Plc Fremgangsmåde til fremstilling af en ikke-krystallinsk anhydratform af paroxetinhydrochlorid

Also Published As

Publication number Publication date
EP0990655A1 (en) 2000-04-05
JP2001072677A (ja) 2001-03-21
EP0990655A4 (en) 2001-10-04
PT990655E (pt) 2003-11-28
CA2294716A1 (en) 1999-10-21
ES2199592T3 (es) 2004-02-16
ATE244237T1 (de) 2003-07-15
AU730652B2 (en) 2001-03-08
DE69909207D1 (de) 2003-08-07
JP3796351B2 (ja) 2006-07-12
DE69909207T2 (de) 2004-04-22
EP0990655B1 (en) 2003-07-02
AU5265699A (en) 1999-11-01
WO1999052902A1 (en) 1999-10-21
US6541637B1 (en) 2003-04-01

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MKLA Lapsed

Effective date: 20130412